[Hub]/) : Traits : Systolic Blood Pressure :

chr5:126,587,995-128,220,643

Best TWAS P=2.54e-14 · Best GWAS P=9.82e-24 conditioned to 2.1e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CTC-228N24.3 0.24 0.15 enet 16 0.20 3.4e-16 -5.59 5.3 1.4e-07 0.21 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum CTC-228N24.3 0.24 0.16 enet 19 0.16 1.8e-08 -5.59 7.3 2.1e-13 0.39 0.93 0.02 FALSE
3 GTEx Artery Aorta CTC-228N24.3 0.20 0.04 lasso 8 0.07 7.4e-05 -4.04 5.3 9.0e-08 0.16 0.77 0.01 FALSE
4 GTEx Artery Coronary CTC-228N24.3 0.31 0.10 lasso 3 0.10 2.9e-04 -5.33 5.9 3.0e-09 0.17 0.10 0.05 FALSE
5 GTEx Artery Tibial CTC-228N24.3 0.20 0.16 lasso 7 0.14 3.0e-11 -5.59 6.3 3.0e-10 0.20 1.00 0.00 FALSE
6 GTEx Brain Caudate basal ganglia CTC-228N24.3 0.28 -0.01 enet 50 0.05 1.2e-02 2.18 7.2 5.7e-13 0.36 0.07 0.23 FALSE
7 GTEx Brain Cerebellar Hemisphere SLC12A2 0.45 -0.01 enet 20 0.01 2.1e-01 -4.94 7.5 8.8e-14 0.43 0.05 0.19 TRUE
8 GTEx Brain Cerebellar Hemisphere CTC-228N24.3 0.25 0.00 lasso 6 0.05 2.2e-02 0.78 6.2 7.2e-10 0.26 0.08 0.08 FALSE
9 GTEx Cells Transformed fibroblasts CTC-228N24.3 0.24 0.16 enet 26 0.16 8.6e-12 -5.59 6.8 1.3e-11 0.19 1.00 0.00 FALSE
10 GTEx Esophagus Mucosa CTC-228N24.3 0.18 0.14 enet 11 0.14 9.8e-10 -5.59 5.6 2.8e-08 0.19 1.00 0.00 FALSE
11 GTEx Esophagus Muscularis CTC-228N24.3 0.24 0.08 enet 29 0.14 1.4e-08 -5.33 7.3 2.3e-13 0.25 0.95 0.00 FALSE
12 GTEx Heart Atrial Appendage CTC-228N24.3 0.22 0.07 lasso 5 0.07 4.1e-04 -5.20 6.7 1.6e-11 0.24 0.46 0.12 FALSE
13 GTEx Heart Left Ventricle CTC-228N24.3 0.24 0.15 lasso 7 0.19 1.9e-10 -5.30 6.2 7.2e-10 0.15 0.98 0.00 FALSE
14 GTEx Lung CTC-228N24.3 0.18 0.14 enet 16 0.14 3.2e-11 -5.59 6.1 1.1e-09 0.22 1.00 0.00 FALSE
15 GTEx Muscle Skeletal CTC-228N24.3 0.25 0.20 lasso 5 0.21 1.6e-20 -5.59 6.3 3.5e-10 0.19 1.00 0.00 FALSE
16 GTEx Nerve Tibial CTC-228N24.3 0.32 0.18 lasso 10 0.16 1.6e-11 -5.33 6.1 8.7e-10 0.23 1.00 0.00 FALSE
17 GTEx Pancreas CTC-228N24.3 0.14 0.19 lasso 2 0.17 1.1e-07 -5.59 5.6 2.2e-08 0.18 0.89 0.01 FALSE
18 GTEx Skin Not Sun Exposed Suprapubic CTC-228N24.3 0.29 0.21 lasso 7 0.22 1.7e-12 -5.59 6.2 4.2e-10 0.30 1.00 0.00 FALSE
19 GTEx Skin Sun Exposed Lower leg CTC-228N24.3 0.29 0.17 enet 12 0.22 4.3e-18 -5.20 5.2 1.6e-07 0.17 1.00 0.00 FALSE
20 GTEx Spleen CTC-228N24.3 0.26 0.03 enet 15 0.05 1.8e-02 -4.04 5.6 2.2e-08 0.09 0.08 0.05 FALSE
21 GTEx Testis CTC-228N24.3 0.30 0.16 lasso 6 0.14 1.1e-06 -5.59 7.6 2.5e-14 0.36 0.78 0.04 TRUE
22 GTEx Thyroid CTC-228N24.3 0.31 0.15 enet 32 0.18 4.6e-14 -5.59 5.7 1.0e-08 0.16 1.00 0.00 FALSE
23 METSIM Adipose CTC-228N24.3 0.17 0.19 lasso 6 0.18 1.9e-26 -5.59 5.6 2.6e-08 0.18 1.00 0.00 FALSE
24 The Cancer Genome Atlas Colon Adenocarcinoma FBN2 0.08 0.10 enet 16 0.09 5.4e-06 4.11 5.5 3.9e-08 0.60 0.52 0.43 FALSE
25 The Cancer Genome Atlas Glioblastoma Multiforme FLJ33630 0.38 0.20 lasso 5 0.17 6.5e-06 -5.59 5.5 3.7e-08 0.18 0.00 0.99 TRUE
26 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FLJ33630 0.10 0.07 lasso 3 0.08 7.0e-09 -5.33 5.6 2.4e-08 0.20 0.00 1.00 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma FLJ33630 0.19 0.16 enet 4 0.16 1.2e-17 -5.61 5.6 2.6e-08 0.18 0.00 1.00 FALSE
28 The Cancer Genome Atlas Lung Adenocarcinoma FLJ33630 0.07 0.05 lasso 1 0.04 1.3e-05 -5.33 5.3 9.9e-08 0.17 0.01 0.99 FALSE
29 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FLJ33630 0.09 0.08 lasso 4 0.09 4.9e-10 -5.59 5.5 3.4e-08 0.18 0.00 1.00 FALSE
30 The Cancer Genome Atlas Prostate Adenocarcinoma SLC12A2 0.04 0.02 enet 17 0.02 3.3e-03 -5.33 -5.6 2.9e-08 -0.17 0.02 0.66 FALSE
31 The Cancer Genome Atlas Testicular Germ Cell Tumors FLJ33630 0.26 0.14 lasso 3 0.13 2.2e-05 -5.59 5.3 1.3e-07 0.16 0.00 0.99 FALSE
32 The Cancer Genome Atlas Thyroid Carcinoma FLJ33630 0.10 0.10 lasso 2 0.09 5.3e-09 -5.61 5.5 3.6e-08 0.19 0.00 1.00 FALSE