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chr5:126,587,995-128,220,643

Best TWAS P=2.54e-14 · Best GWAS P=9.82e-24 conditioned to 2.1e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	CTC-228N24.3	0.24	0.15	enet	16	0.20	3.4e-16	-5.59	5.3	1.4e-07	0.21	1.00	0.00	FALSE
2	GTEx	Adipose Visceral Omentum	CTC-228N24.3	0.24	0.16	enet	19	0.16	1.8e-08	-5.59	7.3	2.1e-13	0.39	0.93	0.02	FALSE
3	GTEx	Artery Aorta	CTC-228N24.3	0.20	0.04	lasso	8	0.07	7.4e-05	-4.04	5.3	9.0e-08	0.16	0.77	0.01	FALSE
4	GTEx	Artery Coronary	CTC-228N24.3	0.31	0.10	lasso	3	0.10	2.9e-04	-5.33	5.9	3.0e-09	0.17	0.10	0.05	FALSE
5	GTEx	Artery Tibial	CTC-228N24.3	0.20	0.16	lasso	7	0.14	3.0e-11	-5.59	6.3	3.0e-10	0.20	1.00	0.00	FALSE
6	GTEx	Brain Caudate basal ganglia	CTC-228N24.3	0.28	-0.01	enet	50	0.05	1.2e-02	2.18	7.2	5.7e-13	0.36	0.07	0.23	FALSE
7	GTEx	Brain Cerebellar Hemisphere	SLC12A2	0.45	-0.01	enet	20	0.01	2.1e-01	-4.94	7.5	8.8e-14	0.43	0.05	0.19	TRUE
8	GTEx	Brain Cerebellar Hemisphere	CTC-228N24.3	0.25	0.00	lasso	6	0.05	2.2e-02	0.78	6.2	7.2e-10	0.26	0.08	0.08	FALSE
9	GTEx	Cells Transformed fibroblasts	CTC-228N24.3	0.24	0.16	enet	26	0.16	8.6e-12	-5.59	6.8	1.3e-11	0.19	1.00	0.00	FALSE
10	GTEx	Esophagus Mucosa	CTC-228N24.3	0.18	0.14	enet	11	0.14	9.8e-10	-5.59	5.6	2.8e-08	0.19	1.00	0.00	FALSE
11	GTEx	Esophagus Muscularis	CTC-228N24.3	0.24	0.08	enet	29	0.14	1.4e-08	-5.33	7.3	2.3e-13	0.25	0.95	0.00	FALSE
12	GTEx	Heart Atrial Appendage	CTC-228N24.3	0.22	0.07	lasso	5	0.07	4.1e-04	-5.20	6.7	1.6e-11	0.24	0.46	0.12	FALSE
13	GTEx	Heart Left Ventricle	CTC-228N24.3	0.24	0.15	lasso	7	0.19	1.9e-10	-5.30	6.2	7.2e-10	0.15	0.98	0.00	FALSE
14	GTEx	Lung	CTC-228N24.3	0.18	0.14	enet	16	0.14	3.2e-11	-5.59	6.1	1.1e-09	0.22	1.00	0.00	FALSE
15	GTEx	Muscle Skeletal	CTC-228N24.3	0.25	0.20	lasso	5	0.21	1.6e-20	-5.59	6.3	3.5e-10	0.19	1.00	0.00	FALSE
16	GTEx	Nerve Tibial	CTC-228N24.3	0.32	0.18	lasso	10	0.16	1.6e-11	-5.33	6.1	8.7e-10	0.23	1.00	0.00	FALSE
17	GTEx	Pancreas	CTC-228N24.3	0.14	0.19	lasso	2	0.17	1.1e-07	-5.59	5.6	2.2e-08	0.18	0.89	0.01	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	CTC-228N24.3	0.29	0.21	lasso	7	0.22	1.7e-12	-5.59	6.2	4.2e-10	0.30	1.00	0.00	FALSE
19	GTEx	Skin Sun Exposed Lower leg	CTC-228N24.3	0.29	0.17	enet	12	0.22	4.3e-18	-5.20	5.2	1.6e-07	0.17	1.00	0.00	FALSE
20	GTEx	Spleen	CTC-228N24.3	0.26	0.03	enet	15	0.05	1.8e-02	-4.04	5.6	2.2e-08	0.09	0.08	0.05	FALSE
21	GTEx	Testis	CTC-228N24.3	0.30	0.16	lasso	6	0.14	1.1e-06	-5.59	7.6	2.5e-14	0.36	0.78	0.04	TRUE
22	GTEx	Thyroid	CTC-228N24.3	0.31	0.15	enet	32	0.18	4.6e-14	-5.59	5.7	1.0e-08	0.16	1.00	0.00	FALSE
23	METSIM	Adipose	CTC-228N24.3	0.17	0.19	lasso	6	0.18	1.9e-26	-5.59	5.6	2.6e-08	0.18	1.00	0.00	FALSE
24	The Cancer Genome Atlas	Colon Adenocarcinoma	FBN2	0.08	0.10	enet	16	0.09	5.4e-06	4.11	5.5	3.9e-08	0.60	0.52	0.43	FALSE
25	The Cancer Genome Atlas	Glioblastoma Multiforme	FLJ33630	0.38	0.20	lasso	5	0.17	6.5e-06	-5.59	5.5	3.7e-08	0.18	0.00	0.99	TRUE
26	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FLJ33630	0.10	0.07	lasso	3	0.08	7.0e-09	-5.33	5.6	2.4e-08	0.20	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	FLJ33630	0.19	0.16	enet	4	0.16	1.2e-17	-5.61	5.6	2.6e-08	0.18	0.00	1.00	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	FLJ33630	0.07	0.05	lasso	1	0.04	1.3e-05	-5.33	5.3	9.9e-08	0.17	0.01	0.99	FALSE
29	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FLJ33630	0.09	0.08	lasso	4	0.09	4.9e-10	-5.59	5.5	3.4e-08	0.18	0.00	1.00	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC12A2	0.04	0.02	enet	17	0.02	3.3e-03	-5.33	-5.6	2.9e-08	-0.17	0.02	0.66	FALSE
31	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FLJ33630	0.26	0.14	lasso	3	0.13	2.2e-05	-5.59	5.3	1.3e-07	0.16	0.00	0.99	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	FLJ33630	0.10	0.10	lasso	2	0.09	5.3e-09	-5.61	5.5	3.6e-08	0.19	0.00	1.00	FALSE