Best TWAS P=9.18e-11 · Best GWAS P=3.16e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | HSPA4 | 0.15 | 0.07 | lasso | 3 | 0.05 | 1.0e-04 | -5.8 | -5.7 | 9.9e-09 | 0.89 | 0.04 | 0.95 | FALSE |
| 2 | GTEx | Testis | HSPA4 | 0.13 | 0.13 | lasso | 2 | 0.12 | 9.1e-06 | -5.8 | -5.8 | 7.5e-09 | 0.92 | 0.07 | 0.91 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HSPA4 | 0.03 | 0.02 | blup | 50 | 0.02 | 5.8e-05 | -6.2 | 6.2 | 6.5e-10 | -0.93 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZCCHC10 | 0.03 | 0.02 | blup | 30 | 0.02 | 1.3e-05 | -6.2 | 6.5 | 9.2e-11 | -0.97 | 0.01 | 0.99 | TRUE |