Hub : Genes

HSPA4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Muscle Skeletal	0.1275	0.0340	1.3e-06	0.086	NA	0.095	NA	0.081	8.0e-09	NA	1.5e-09	NA	2.5e-08
2	GTEx	Nerve Tibial	0.1493	0.0569	1.3e-03	0.072	NA	0.026	NA	0.054	7.9e-06	NA	5.4e-03	NA	1.0e-04
3	GTEx	Testis	0.1290	0.0510	4.8e-03	0.133	NA	0.084	NA	0.115	1.7e-06	NA	1.4e-04	NA	9.1e-06
4	METSIM	Adipose	0.0938	0.0291	5.9e-06	0.016	0.034	0.022	0.038	0.024	1.6e-03	6.5e-06	2.5e-04	1.7e-06	1.2e-04
5	YFS	Blood	0.1687	0.0320	0.0e+00	0.024	0.088	0.085	0.087	0.054	1.8e-08	2.8e-27	2.0e-26	6.6e-27	4.0e-17
6	TCGA	Breast Invasive Carcinoma	0.0259	0.0147	7.4e-05	0.020	0.019	0.009	NA	0.014	5.2e-05	5.8e-05	5.1e-03	NA	4.8e-04
7	TCGA	Brain Lower Grade Glioma	0.0870	0.0363	1.0e-05	0.008	0.047	0.035	NA	0.016	3.9e-02	4.1e-06	6.1e-05	NA	5.8e-03
8	TCGA	Lung Adenocarcinoma	0.0710	0.0396	4.0e-03	0.002	0.005	0.003	NA	0.009	1.9e-01	8.1e-02	1.5e-01	NA	3.0e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.2	2.0	5.1	-1.0	-1.9	-1.7	-2.3	0.0	1.3	-1.2	0.0
Bipolar Disorder or Schizophrenia	1.4	3.4	6.3	-1.1	-2.5	-2.4	-2.3	0.4	2.3	-1.7	0.0
Depressed Affect (Nagel 2018)	0.2	0.5	1.8	0.5	-0.2	-0.4	-0.6	-0.8	1.3	0.1	0.8
Depression (Nagel 2018)	2.4	3.6	6.7	-2.3	-2.6	-2.4	-1.9	0.1	2.0	-1.8	0.4
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.2	0.2	0.5	0.0	-1.1	1.5	0.2	-0.8	-0.6
Neuroticism (Nagel 2018)	0.3	0.7	2.7	-0.1	-0.3	-0.8	-0.6	-0.2	1.6	0.3	1.2
Schizophrenia (2018)	0.8	1.6	3.5	-0.7	-1.7	-1.8	-1.1	0.4	1.9	-1.3	0.0
Schizophrenia vs Biploar Disorder	2.1	2.8	8.2	2.1	1.7	0.8	2.4	-0.4	0.0	2.9	0.0
Worry (Nagel 2018)	0.2	0.3	0.8	0.5	0.3	-0.4	0.7	0.3	0.9	0.7	0.7
Alzheimer’s Disease (in mother)	0.6	0.6	2.0	1.0	0.8	1.0	0.6	-0.5	-0.1	1.4	0.1
Alzheimer’s Disease (in father)	2.4	2.6	5.0	1.9	2.2	2.2	0.1	-1.3	-2.1	0.8	-0.1
Alzheimer’s Disease (including proxy)	3.2	4.6	8.4	2.4	2.8	2.9	1.5	-2.0	-2.2	1.9	-0.3
Crohns Disease (2017)	1.9	4.2	8.9	1.7	1.7	2.2	1.2	-2.2	-3.0	-0.3	-2.7
Irritable Bowel Disease (IBD)	1.4	3.4	6.5	1.7	1.8	2.0	1.1	-1.8	-2.5	-0.2	-2.5
Ulcerative Colitis (UC)	0.5	0.9	1.9	1.0	1.1	1.0	0.8	-0.7	-1.0	0.1	-1.4
Major Depression (MDD)	1.1	1.4	6.0	-1.3	-0.8	-1.0	-0.4	2.5	0.8	-0.2	0.7
Reaction Time	0.6	1.1	2.9	1.3	1.0	0.6	-0.3	-1.6	0.0	0.5	1.7
Verbal and Numeric Reasoning (VNR)	0.3	0.8	3.5	0.5	1.1	0.8	0.9	1.9	-0.3	-0.2	-0.1
Breast Cancer	7.0	16.8	32.4	4.6	5.5	5.7	0.9	-2.8	-5.2	3.8	0.1
Ovarian Cancer	0.4	0.5	1.1	0.2	0.5	1.1	-0.4	-0.8	-1.0	0.4	0.7
Prostate Cancer	2.2	3.1	6.2	-1.6	-1.9	-2.4	-1.2	2.1	2.5	-1.0	-0.2
Age at First Birth	0.6	0.9	1.8	1.2	1.1	1.1	0.3	-1.3	-1.1	0.4	-0.1
Bipolar Disorder (2011)	1.1	1.1	2.2	-0.8	-1.1	-1.1	-1.5	1.2	0.8	-1.2	0.0
Body Mass Index (BMI) (2010)	1.0	1.4	3.2	-1.0	-1.4	-1.5	-1.2	0.8	1.0	-1.8	-0.6
Coronary Artery Disease (CAD)	0.3	0.3	0.8	-0.9	-0.6	-0.2	0.2	-0.8	0.0	-0.8	0.0
Crohns Disease (2012)	0.5	0.7	2.3	0.5	0.6	1.1	0.4	-1.3	-1.5	-0.3	0.0
Mean Putamen Volume	0.3	0.3	1.2	-0.0	-0.2	-0.3	-0.7	-0.7	0.2	0.3	1.1
Fasting Glucose	0.1	0.1	0.5	0.0	-0.2	-0.1	-0.1	-0.3	0.3	-0.2	0.7
HbA1C	0.6	0.6	1.8	-0.5	-1.4	-1.2	-0.5	0.6	0.7	-0.4	0.5
HDL Cholesterol	1.1	1.9	3.3	1.8	1.6	1.8	0.2	-0.2	-1.8	-0.5	-1.6
LDL Cholesterol	0.6	0.9	5.3	0.2	0.7	0.6	0.0	-2.3	-1.0	-0.4	0.2
Lupus	4.2	6.3	10.0	-2.7	-2.5	-2.9	-1.1	3.0	3.2	-2.7	-1.1
Neuroticism (2016)	0.5	0.7	1.6	1.3	0.7	0.4	0.8	0.8	0.7	0.9	0.8
Primary Biliary Cirrhosis	0.6	0.9	3.5	-0.1	-0.3	-0.5	1.2	1.2	0.6	-0.3	-1.9
Rheumatoid Arthritis	0.4	0.5	1.2	0.9	0.8	0.5	0.6	0.9	-0.1	1.1	-0.5
Schizophrenia (2014)	1.3	2.8	7.3	-0.7	-2.2	-2.6	-1.2	0.5	2.7	-1.0	0.0
Triglycerides	2.4	3.9	8.3	-2.5	-2.6	-2.7	-0.3	1.5	2.9	-0.5	0.5
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.8	-1.1	-0.3	-0.1	0.3	1.3	-0.3	0.2	0.0
Ulcerative Colitis	0.4	0.6	1.4	0.5	0.9	1.2	1.0	0.2	-1.1	-0.2	0.0
Blood Eosinophil Count	1.9	14.8	47.7	3.4	3.6	2.7	-6.9	-1.9	-2.7	4.8	2.3
Blood Platelet Count	0.9	10.2	18.9	3.3	4.0	3.4	3.1	-1.5	-2.8	4.3	2.0
Blood Red Count	0.1	0.8	2.5	-0.9	-0.4	-0.1	0.5	-1.1	0.4	1.2	1.6
Blood White Count	0.6	4.4	9.2	-2.4	-2.4	-2.8	-0.8	0.0	3.0	0.9	2.2
Heel T-Score	7.9	62.9	112.4	9.7	10.6	10.2	4.5	-6.4	-9.2	6.9	-0.7
BMI	0.2	1.0	1.6	-0.7	-1.1	-1.3	-0.9	-0.6	1.2	-0.6	1.2
Height	0.2	3.1	8.1	1.5	1.4	1.8	1.3	-1.4	-1.5	-1.8	-2.8
Waist Hip Ratio (WHR)	9.4	42.2	68.6	-7.4	-8.3	-8.1	-3.7	5.8	8.1	-6.0	-0.1
Systolic Blood Pressure	4.3	21.3	38.2	-5.0	-5.7	-5.8	-3.0	4.9	6.2	-2.5	1.7
Smoking Status	0.1	0.3	1.3	-0.3	-0.1	-0.2	-0.6	-0.4	-0.2	0.3	1.2
Allergy or Eczema	1.7	4.5	12.0	1.5	3.5	3.2	-0.0	-0.7	-2.4	2.3	0.1
Cardiovascular Disease	5.0	16.6	32.9	-4.2	-5.1	-5.4	-2.9	3.1	5.7	-2.7	1.3
Hypothyroidism (self reported)	0.3	0.7	1.3	0.7	0.9	0.8	0.9	-1.1	-0.5	0.3	-1.1
Respiratory disease	1.3	2.9	6.7	1.4	2.6	2.4	-1.3	-1.1	-2.0	1.3	-0.0
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.4	-0.3	-0.5	-0.5	-1.2	-0.9	0.5	-0.5	0.2
Lung FEV1/FVC ratio	6.7	34.0	64.3	-5.6	-8.0	-7.6	-3.2	3.7	7.7	-6.0	-0.4
Lung FVC	3.2	16.0	37.5	-3.7	-4.4	-4.9	0.5	6.1	5.6	-0.7	1.3
Neuroticism	0.2	0.6	2.1	-0.1	-0.6	-1.0	-0.4	0.8	1.5	0.2	0.5
Chronotype (morning person)	1.3	3.0	7.7	1.5	1.9	1.9	1.0	-1.3	-2.8	1.7	-1.1
Hair Pigment	0.1	4.1	7.8	2.5	2.8	2.4	2.3	-0.9	-1.7	1.4	-1.3
Tanning	0.1	0.9	2.9	-0.1	0.4	1.0	-0.4	-1.4	-1.7	-0.7	-0.6
Hand grip strength (left)	1.3	3.5	10.7	1.0	2.0	2.6	0.5	-2.1	-3.3	-0.1	-0.7
Number of treatments/medications taken	3.8	6.8	11.7	-3.0	-3.4	-3.3	-3.4	0.6	2.8	-1.9	-0.2
Average weekly spirits intake	4.3	5.3	10.1	-2.3	-2.4	-2.7	-1.4	3.2	2.8	-2.0	0.3
Sensitivity / hurt feelings	1.6	2.7	7.9	-1.7	-1.5	-2.1	-0.9	1.2	2.8	-0.1	1.5
Frequency of depressed mood in last 2 weeks	1.4	2.0	3.1	-0.6	-1.7	-1.7	-1.8	-0.7	1.5	-1.2	1.7
Hearing difficulty/problems: Yes	0.6	0.9	2.0	-0.8	0.9	1.3	0.6	-0.7	-1.4	0.9	-0.4
Relative age of first facial hair	5.7	11.7	23.5	4.8	4.5	4.3	1.6	-1.4	-4.1	3.2	0.0
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	8.5	0.6	-0.1	-0.0	-2.9	-1.4	-0.2	-1.4	-0.5
Ever used hormone-replacement therapy (HRT)	1.5	1.9	5.3	-0.7	-1.9	-1.9	-0.9	-0.0	2.3	-0.9	0.8
Ever had hysterectomy (womb removed)	2.3	2.6	6.9	-0.6	-1.7	-2.0	-0.4	-0.6	2.6	0.6	2.4
Systolic blood pressure, automated reading	1.0	2.8	6.3	-1.3	-2.5	-2.4	-1.2	0.8	2.5	-0.7	0.6
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.6	-0.2	-0.7	-0.6	-1.6	-1.0	0.9	-0.6	0.7
Angina	1.9	2.5	5.0	-1.7	-2.2	-1.9	-1.7	0.8	1.4	-1.6	-0.6
Medication for hormone replacement therapy	0.8	0.9	2.0	-1.0	-1.4	-1.4	0.3	0.6	1.3	-0.4	-0.4
Vitamin and mineral supplements	0.2	0.3	1.0	0.1	-0.1	0.2	-0.2	0.6	-1.0	0.2	-0.7
Supplements: Zinc	1.1	1.2	5.4	-0.7	0.5	0.1	-1.3	-1.3	0.4	0.5	2.3
Medication: Co-codamol	0.3	0.4	1.5	-0.2	0.2	0.7	-0.9	-1.2	-0.2	0.1	0.3
Medication: Metformin	0.5	0.8	3.0	-0.4	-0.8	-0.7	-1.1	-0.6	0.6	-0.1	1.7
Diabetes (father)	0.2	0.3	0.9	-0.6	-0.2	-0.5	-0.1	0.9	0.6	0.5	-0.1
Diabetes (mother)	1.1	1.4	3.6	-1.4	-1.1	-1.2	-1.3	0.3	1.9	-1.0	0.5
Severe depression (siblings)	2.0	2.2	3.4	-0.6	-1.5	-1.4	-1.4	1.9	1.7	-1.7	-1.3
Pack years adult smoking proportion	3.6	5.5	9.1	-3.0	-2.8	-2.7	-2.6	1.6	2.1	-2.5	0.5
Impedance of leg (right)	0.8	4.1	10.2	1.5	2.4	2.5	1.1	0.5	-3.2	0.1	-2.6
Leg fat-free mass (left)	0.1	0.6	1.9	-0.4	-0.6	-0.7	-0.6	-1.4	0.9	-0.5	0.5
Trunk fat percentage	0.2	1.0	2.3	-0.7	-0.9	-0.8	-0.9	-1.0	0.3	-1.5	-1.3
Hand grip strength (right)	1.3	3.4	9.7	1.2	2.0	2.6	0.2	-2.1	-3.1	-0.6	-0.7
Townsend deprivation index at recruitment	0.9	1.2	3.9	-0.5	-1.4	-1.7	0.4	0.3	2.0	0.4	0.8
Current tobacco smoking	0.5	0.9	2.6	-1.6	-1.0	-1.1	-0.7	0.2	0.7	0.0	0.9
Average weekly fortified wine intake	1.2	1.5	2.8	-1.4	-1.2	-1.3	-1.7	0.6	0.9	-1.6	0.3
Maternal smoking around birth	0.1	0.1	0.4	0.0	0.1	0.2	-0.3	-0.5	-0.7	0.2	0.1
Fed-up feelings	0.4	0.8	3.4	0.9	-0.2	-0.2	-0.6	-1.8	1.1	0.3	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.5	3.8	-1.9	-1.9	-1.9	-1.5	0.2	1.9	-1.6	0.4
Relative age voice broke	4.2	6.5	10.3	3.0	3.2	3.2	2.1	-2.0	-2.5	2.7	0.4
Taking other prescription medications	0.3	0.5	1.8	-0.5	-0.5	-0.5	-1.3	-0.9	0.5	0.2	0.8
Age when periods started (menarche)	1.5	3.6	6.2	2.5	2.2	2.2	1.8	-2.0	-1.6	1.7	-0.3
Bilateral oophorectomy (both ovaries removed)	1.9	2.2	4.9	-1.2	-1.8	-1.9	-0.5	0.3	2.0	-0.3	2.2
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.4	6.2	2.5	2.5	2.4	1.3	-1.5	-2.0	0.8	-0.8
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.4	-0.4	-0.4	-0.3	-1.1	-0.5	0.2	-1.2	-0.4
Qualifications: CSEs or equivalent	2.6	3.5	5.1	1.5	2.1	2.0	2.1	-2.1	-1.8	2.3	0.8
Serious illness, injury or assault to yourself	1.7	2.1	4.7	-1.6	-1.2	-0.8	-1.9	-1.9	0.4	-2.2	0.6
High blood pressure	3.5	9.9	19.3	-3.6	-4.4	-4.3	-2.1	2.2	4.2	-0.8	0.7
Hayfever, allergic rhinitis or eczema	1.7	3.8	9.9	1.7	3.1	2.7	-0.2	-0.6	-1.9	2.3	0.9
Multivitamins +/- minerals	0.7	0.9	2.3	1.2	1.5	1.3	0.6	-1.1	-0.6	0.4	0.4
Stomach or abdominal pain in last month	4.0	5.0	8.5	-2.1	-2.9	-2.6	-2.1	-0.4	2.9	-2.5	1.3
Supplements: Glucosamine	0.6	0.7	1.5	0.9	1.2	1.2	0.9	-0.2	-0.5	0.1	-0.9
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	3.6	0.7	1.6	1.6	-0.7	-1.1	-1.9	0.1	-0.6
Medication: Atenolol	2.5	3.1	6.6	-2.6	-2.0	-1.8	-1.4	1.7	1.4	-1.9	-0.4
Medication: Levothyroxine sodium	0.3	0.5	1.3	-0.6	-0.1	-0.3	1.1	0.3	1.1	-0.2	-1.1
Sitting height	0.0	0.3	1.0	0.0	0.6	0.5	1.0	-0.1	-0.4	-0.3	-0.9
Chronic bronchitis/emphysema (father)	0.6	0.7	3.1	-0.5	-0.4	-0.5	-1.8	0.1	-0.5	-0.5	-1.1
High blood pressure (mother)	0.2	0.3	0.8	0.1	-0.4	-0.3	0.9	0.1	0.9	0.9	0.3
Body mass index (BMI)	0.1	0.6	2.6	0.1	-0.6	-0.8	-0.6	-1.6	0.8	-0.0	0.6
Impedance of leg (left)	0.8	3.8	8.7	1.5	2.4	2.5	1.5	0.6	-3.0	0.1	-2.2
Leg predicted mass (left)	0.1	0.6	2.0	-0.5	-0.7	-0.7	-0.7	-1.4	1.0	-0.5	0.6
Trunk fat mass	0.2	0.8	1.9	-0.3	-0.6	-0.5	-0.7	-1.4	0.1	-1.3	-1.2
Waist circumference	1.8	6.5	12.5	-2.6	-3.5	-3.5	-1.4	1.0	3.5	-2.3	0.1
Number of incorrect matches in round	0.1	0.2	0.8	-0.2	-0.9	-0.4	0.0	-0.3	0.3	0.2	0.6
Past tobacco smoking	0.1	0.2	0.5	-0.4	-0.7	-0.7	0.5	-0.1	0.5	-0.3	-0.4
Alcohol usually taken with meals	0.2	0.4	0.7	0.3	0.7	0.8	0.2	-0.2	-0.7	0.7	0.7
Nervous feelings	0.6	1.1	4.0	0.3	0.3	-0.4	0.3	-0.9	1.0	1.7	2.0
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.4	0.1	-0.3	-0.4	-1.2	-0.2	0.8	-0.5	0.9
Hearing difficulty/problems with background noise	0.2	0.4	1.3	-1.0	-0.4	-0.4	-1.1	-0.0	0.0	-0.3	-0.2
Hair/balding pattern: Pattern 2	2.0	2.5	5.1	0.7	2.1	2.1	0.8	-1.9	-2.3	1.2	0.1
Had menopause	0.9	1.1	4.1	0.8	0.2	0.0	-0.6	-2.0	0.8	1.2	1.2
Had other major operations	0.7	0.9	2.8	-0.8	-1.0	-0.7	-1.7	-0.0	0.4	-1.3	0.5
Forced vital capacity (FVC)	1.6	6.1	17.3	-2.3	-2.6	-2.9	0.3	4.2	3.1	-0.5	1.1
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.5	8.7	3.0	2.6	2.4	1.1	-0.6	-1.8	0.8	-1.3
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	2.3	-1.0	-0.9	-0.9	-1.1	-0.1	0.7	-1.5	-0.4
Qualifications: None of the above	0.2	0.4	1.1	0.9	0.2	0.3	0.5	-0.4	-0.8	1.1	-0.3
Financial difficulties in last 2 years	0.7	1.0	3.2	-0.3	-0.8	-1.3	-0.3	0.8	1.8	-1.1	-0.3
Mouth/teeth dental problems	0.1	0.2	0.9	0.1	-0.3	-0.2	-0.0	1.0	-0.3	0.2	-0.1
Heart attack	0.3	0.4	1.0	0.8	-0.3	0.0	1.0	0.5	-0.5	0.5	-0.5
Allergy	3.4	7.7	17.3	-2.7	-4.2	-3.9	-0.3	1.9	3.2	-2.9	-0.1
Pain all over the body in last month	0.3	0.3	1.0	-0.1	-0.1	0.3	1.0	-0.4	0.2	0.9	0.2
Diabetes (self-reported)	0.3	0.5	2.2	-0.2	-0.6	-0.3	-1.5	-0.9	-0.2	-0.1	0.8
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	3.2	-1.0	0.2	0.0	-0.0	1.8	0.3	-0.1	0.1
Medication: Ramipril	1.1	1.4	5.1	-0.7	-0.9	-0.8	0.6	2.3	1.0	-0.8	-1.5
Medication: Simvastatin	6.2	9.1	17.6	-3.1	-4.2	-3.6	-2.8	1.7	3.0	-3.5	-0.2
Fluid intelligence score	0.9	1.8	8.4	-1.0	-1.0	-1.3	-0.4	2.9	1.3	-0.9	-0.1
Illnesses of siblings	2.2	3.1	5.4	1.6	2.2	2.3	2.3	0.0	-2.2	0.8	-1.2
Neuroticism score	0.2	0.5	1.9	1.0	0.3	-0.3	-0.0	0.2	1.4	0.4	0.6
Weight	0.1	0.4	2.2	0.1	-0.2	-0.3	-0.2	-1.5	0.4	-0.4	0.0
Impedance of arm (right)	1.1	5.3	8.0	-2.7	-2.7	-2.1	-1.2	2.8	1.4	-2.8	-1.8
Arm fat percentage (right)	0.5	2.1	4.0	-1.5	-2.0	-1.8	-1.5	-0.4	1.3	-1.7	-0.8
Trunk fat-free mass	0.1	0.9	1.9	1.3	1.2	1.0	0.3	-1.4	-0.7	0.4	0.3
Hip circumference	0.1	0.4	2.7	0.7	0.3	0.1	0.3	-1.6	-0.1	0.5	0.2
Time employed in main current job	0.4	0.5	1.7	1.3	1.1	0.6	-0.1	-0.9	-0.0	0.2	0.0
Alcohol intake versus 10 years previously	2.5	3.8	10.0	1.7	2.4	1.8	1.2	-3.2	-1.7	2.1	-0.0
Father’s age at death	0.6	0.9	2.5	0.0	0.2	0.5	-1.4	0.2	-1.3	-0.5	-1.6
Worrier / anxious feelings	0.3	0.5	2.2	0.7	0.8	-0.0	-0.1	0.0	1.5	0.0	0.8
Frequency of tiredness / lethargy in last 2 weeks	5.0	8.2	12.0	-3.1	-3.4	-3.2	-3.4	0.7	3.5	-2.6	1.8
Falls in the last year	0.5	0.7	2.9	-0.4	-1.0	-0.9	0.1	-0.6	1.7	-0.2	0.4
Hair/balding pattern: Pattern 3	2.2	3.3	7.4	-1.3	-2.3	-2.3	-1.1	1.8	2.7	-1.4	-0.1
Number of live births	0.7	0.9	3.1	0.5	0.5	1.2	0.6	-1.1	-1.8	0.1	-0.9
Forced expiratory volume in 1-second (FEV1)	3.4	11.6	23.8	-3.2	-4.1	-4.2	-0.2	4.5	4.9	-1.6	1.1
Pulse rate	2.1	3.6	6.8	-1.9	-2.1	-2.1	-1.5	-1.8	1.9	-0.6	2.6
Happiness	0.6	0.7	2.4	-0.6	-0.8	-0.8	-0.7	-0.1	0.8	-1.5	-0.8
Noisy workplace	0.4	0.5	1.9	-0.5	-0.0	0.1	-1.1	0.0	0.1	-1.4	-0.9
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.6	0.0	-0.2	-0.7	-0.4	1.0	1.3	-1.1	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.7	1.0	0.5	0.6	-1.1	-1.6	-0.3	-0.6	0.2
Mouth/teeth dental problems: Dentures	0.9	1.5	2.6	1.4	1.4	1.4	-0.2	-1.2	-1.6	-0.1	-1.5
Asthma	3.0	6.0	13.3	2.3	3.7	3.3	-0.3	-1.8	-3.2	2.3	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.8	-0.1	-0.9	-0.1	-0.6	-0.6	-0.2	0.0	-0.2
Medication: Cholesterol lowering	1.7	2.6	5.8	-1.7	-2.4	-2.0	-1.2	0.1	1.8	-1.7	-0.3
Depression (self-reported)	0.5	0.6	1.6	-0.7	-0.8	-1.1	-0.3	1.3	0.9	0.2	-0.1
Medication: Lansoprazole	0.5	0.5	1.7	0.0	0.2	0.2	-0.7	-1.3	-1.1	-0.1	-0.9
Prospective memory result	0.9	1.1	3.5	-0.9	-1.4	-0.6	-1.2	-0.5	-0.2	-1.9	-0.4
Lung cancer (father)	0.3	0.4	1.1	0.4	0.2	0.3	1.0	-0.8	-0.4	0.2	-1.0
Illnesses of mother	0.9	1.1	4.2	-1.0	-0.7	-0.7	0.3	2.1	0.5	-1.3	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	3.7	11.8	22.4	-3.3	-4.2	-4.3	-0.4	4.6	4.7	-1.6	1.3
Pulse wave Arterial Stiffness index	1.7	2.0	5.5	-1.7	-2.3	-2.1	-0.4	0.2	1.5	-0.8	0.5
Impedance of arm (left)	1.0	4.7	7.3	-2.6	-2.5	-2.1	-0.8	2.7	1.5	-2.5	-1.8
Arm fat mass (right)	0.3	1.1	2.0	-0.9	-1.4	-1.3	-1.1	-1.0	0.9	-1.2	-0.2
Trunk predicted mass	0.2	0.9	1.8	1.3	1.2	1.0	0.3	-1.4	-0.7	0.4	0.2
Standing height	0.0	0.4	0.9	0.1	0.7	0.8	0.5	-0.2	-0.6	-1.0	-0.8
Length of working week for main job	0.1	0.2	0.5	0.0	0.2	0.2	0.3	-0.5	0.4	-0.7	-0.1
Exposure to tobacco smoke at home	0.6	0.7	1.4	1.2	0.2	0.7	-0.7	-1.0	-1.1	1.1	-0.2
Breastfed as a baby	0.6	0.7	4.4	0.2	-0.2	-0.1	2.1	-0.1	1.0	0.3	-0.4
Tense / ‘highly strung’	0.2	0.4	0.7	0.5	-0.1	-0.5	-0.7	0.8	0.5	-0.6	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	5.5	0.1	-0.4	-0.8	-1.0	-0.5	1.2	0.4	2.3
Hair/balding pattern: Pattern 4	4.8	11.6	20.9	-4.0	-4.6	-4.2	-0.9	4.3	3.9	-2.1	0.4
Birth weight of first child	0.3	0.5	0.9	-0.9	-0.8	-0.9	0.4	0.6	0.9	-0.4	0.4
Peak expiratory flow (PEF)	3.6	8.2	15.9	-3.6	-3.7	-3.6	-0.7	2.1	4.0	-2.0	1.1
Pulse wave reflection index	0.5	0.7	2.2	-0.8	-0.6	-0.6	0.5	1.5	0.6	1.0	0.2
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.6	-0.8	-0.4	-0.5	-0.5	-0.3	0.1	-0.2	0.2
Loud music exposure frequency	0.8	0.9	2.4	0.9	1.5	1.2	-0.4	0.2	-1.4	0.4	-0.2
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	2.6	0.7	0.6	0.4	0.7	1.6	0.8	-0.9	-1.3
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	6.4	0.6	0.7	0.6	2.5	-0.5	0.7	1.4	1.0
Blood clot in the leg (DVT)	0.9	1.2	2.8	-1.4	-1.6	-1.0	-0.6	-0.3	0.7	-1.7	-0.8
Medication: Paracetamol	0.8	1.4	4.2	0.0	-0.3	-0.4	-1.6	-2.0	0.7	0.2	1.8
Headache pain in last month	4.3	7.4	13.7	-3.2	-3.7	-3.5	-1.3	1.3	3.5	-2.6	0.7
Medication for cholesterol, blood pressure or diabetes	4.7	7.8	17.2	3.1	4.1	3.8	1.4	-1.3	-3.5	2.2	0.3
Glaucoma (self-reported)	0.4	0.5	1.9	-0.1	-0.4	-0.3	-1.4	-1.2	0.1	-0.2	0.6
Gout (self-reported)	1.4	1.9	4.7	1.3	1.2	1.4	-0.7	-2.0	-2.2	-0.4	-0.7
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	1.3	0.6	1.1	1.1	0.8	-1.1	-0.9	0.9	-1.0
Medication: Amlodipine	2.7	3.7	7.7	-1.9	-2.5	-2.5	-1.5	0.3	2.8	-0.9	1.7
Medication: Ventolin 100micrograms inhaler	0.8	1.1	2.2	0.9	1.5	1.2	-1.4	-0.7	-1.0	0.3	-0.7
Birth weight	2.8	6.2	13.7	2.1	2.8	3.4	0.6	-2.8	-3.7	0.4	-1.9
Chronic bronchitis/emphysema (mother)	1.8	2.1	3.6	-1.6	-1.5	-1.3	-0.4	1.9	1.2	-1.9	-1.1
High blood pressure (siblings)	3.8	5.5	9.5	-2.4	-2.7	-3.1	-2.9	-0.4	2.8	-1.2	1.9
Forced vital capacity (FVC), Best measure	1.4	5.2	14.8	-2.2	-2.5	-2.6	0.1	3.9	2.8	-0.6	0.6
Body fat percentage	0.2	0.6	2.0	-0.1	-0.3	-0.2	-0.6	-1.4	-0.3	-0.9	-1.3
Leg fat percentage (right)	0.4	1.3	3.3	1.0	1.1	1.0	0.0	-1.8	-1.6	0.4	-1.2
Arm fat-free mass (right)	0.5	2.6	7.3	1.8	2.0	1.7	0.6	-2.7	-1.3	1.1	0.6
Exposure to tobacco smoke outside home	1.0	1.3	5.2	0.3	0.5	0.9	-1.0	-2.3	-1.5	-0.9	-0.4
Comparative body size at age 10	0.2	0.6	1.0	0.5	1.0	1.0	-0.9	0.1	-0.9	-0.7	-0.6
Number of full brothers	0.7	0.9	3.6	-1.0	-0.7	-0.2	-0.4	0.1	-0.3	-1.9	-1.4
Worry too long after embarrassment	2.2	3.7	9.3	-1.5	-1.5	-2.3	-1.9	1.0	3.1	-0.9	2.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	2.6	-0.8	-1.1	-1.0	-1.5	0.1	1.6	-1.0	0.6
Wheeze or whistling in the chest in last year	2.1	3.8	9.6	1.4	2.1	2.5	-1.4	-3.1	-2.4	0.3	-0.5
Number of children fathered	0.9	1.0	3.4	-0.2	0.2	0.2	-1.1	-0.0	-1.1	-1.5	-1.8
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.3	1.0	0.8	0.6	0.3	-0.9	-1.1	0.0	0.2
Age at first live birth	1.7	2.9	6.7	-2.2	-1.5	-1.2	-1.1	2.6	0.7	-2.2	-1.1
Pulse wave peak to peak time	1.6	1.8	5.0	1.5	2.2	2.0	0.4	0.1	-1.5	0.6	-0.6
Health satisfaction	0.3	0.4	1.2	-0.5	-0.7	-0.5	-0.4	-0.6	0.7	-1.1	-0.1
Shortness of breath walking on level ground	0.7	0.8	4.2	-0.0	0.9	0.9	-0.0	-2.0	-0.4	0.3	-0.6
Qualifications: College or University degree	1.7	5.4	8.2	-2.5	-2.9	-2.7	-1.7	2.2	2.8	-2.3	0.6
Eye problems/disorders: None of the above	1.4	1.7	6.9	0.8	0.5	0.3	1.0	2.6	-0.0	-1.0	-1.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.7	0.3	-0.3	-0.9	0.7	-0.2	1.3	0.1	1.1
Emphysema/chronic bronchitis	0.9	1.0	6.4	0.7	0.3	0.5	-0.6	-2.5	-0.4	-0.7	-0.2
Medication for pain relief, constipation, heartburn	0.7	1.3	3.0	1.5	1.7	1.3	0.8	0.3	-1.4	0.4	-0.5
Neck or shoulder pain in last month	0.5	0.8	2.5	1.2	0.3	0.3	-0.6	-1.1	-0.4	0.5	1.6
Medication: Blood pressure	4.7	8.2	16.7	-3.3	-4.1	-3.7	-1.7	2.3	2.8	-2.5	-1.5
Angina (self-reported)	1.9	2.4	4.8	-1.7	-2.2	-1.9	-1.7	0.9	1.4	-1.5	-0.6
Migraine (self-reported)	0.6	0.8	1.4	-1.0	-1.0	-1.0	-0.6	0.9	1.2	-0.0	0.7
Medication: Ibuprofen	0.2	0.2	0.7	-0.3	-0.8	-0.1	-0.5	-0.6	-0.3	0.1	-0.5
Medication: Allopurinol	1.7	2.3	6.1	0.9	1.3	1.7	-0.5	-2.5	-2.5	-0.6	-0.0
Medication: Omeprazole	1.7	2.1	5.8	-0.7	-1.5	-1.5	-0.7	-0.4	2.3	0.0	2.4
Medication: Seretide 50 evohaler	8.3	9.6	18.1	3.7	4.2	4.1	1.1	-2.3	-3.5	3.0	-0.7
Mean time to correctly identify matches	0.2	0.4	1.0	0.9	0.5	0.2	-0.1	-1.0	0.7	0.4	0.6
Heart disease (mother)	0.7	0.8	1.2	1.1	1.0	1.0	1.0	-1.0	-0.6	1.0	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.1	5.9	0.8	1.6	1.4	0.7	-2.4	-1.7	1.6	0.1
Whole body fat mass	0.1	0.5	3.0	0.1	-0.2	-0.2	-0.4	-1.7	-0.0	-0.7	-0.8
Leg fat mass (right)	0.2	0.9	4.8	0.6	0.5	0.5	-0.2	-2.2	-0.9	-0.1	-0.9
Arm predicted mass (right)	0.4	2.2	5.8	1.7	1.8	1.5	0.6	-2.4	-1.1	1.0	0.7
Pulse rate, automated reading	2.9	9.3	18.4	-3.6	-4.3	-4.3	-2.9	0.4	3.1	-2.1	1.8
Alcohol intake frequency.	2.1	5.0	16.2	1.6	1.8	1.2	1.4	-4.0	-0.2	3.5	1.5
Comparative height size at age 10	0.1	0.6	3.8	-0.0	-0.2	0.4	0.2	0.7	-0.4	-0.6	-2.0
Number of full sisters	1.5	1.8	4.6	-1.5	-1.7	-2.1	-0.3	0.9	1.5	-1.0	0.5
Suffer from ‘nerves’	0.0	0.1	0.2	0.5	-0.0	-0.2	-0.3	-0.1	0.1	0.0	0.5
Overall health rating	1.6	3.4	9.3	-1.7	-2.3	-2.3	-1.1	0.1	3.0	-0.5	1.8
Chest pain or discomfort	1.9	2.8	6.6	-1.6	-2.0	-1.6	-2.6	-0.6	1.4	-1.8	0.9
Had major operations	1.9	2.2	4.3	-1.9	-2.1	-2.0	-0.9	1.3	1.6	-0.7	0.4
Age at last live birth	3.2	4.6	8.4	-2.3	-2.9	-2.6	-1.7	1.3	2.2	-2.7	0.4
Family relationship satisfaction	0.2	0.2	0.7	0.8	0.2	0.3	-0.4	0.3	-0.1	-0.9	-0.1
Leg pain on walking	1.7	2.1	4.4	-1.6	-1.7	-1.7	-1.5	-0.7	2.1	-1.1	0.1
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	3.5	0.7	1.0	0.9	0.2	-1.7	-1.2	1.2	1.9
Commuting to job workplace: Car/motor vehicle	1.2	1.4	4.4	-0.7	0.3	0.7	1.5	1.0	-1.3	-0.7	-2.1
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	3.3	-0.5	-0.4	-0.7	-0.0	1.8	0.9	0.3	0.7
Medication: Aspirin	2.4	3.1	6.2	-2.5	-2.4	-2.1	-0.9	1.8	1.4	-1.3	-1.1
Supplements: Vitamin C	2.3	2.7	8.8	-0.8	-1.1	-1.4	0.7	0.6	2.6	1.2	3.0
Knee pain experienced in last month	1.5	2.3	4.9	-1.2	-1.8	-1.9	-0.1	1.1	2.2	-1.6	-1.3
Hypertension (Self-reported)	3.7	10.2	19.7	-3.6	-4.4	-4.4	-2.6	1.9	4.2	-1.0	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.9	-0.3	-0.5	-0.5	0.2	-1.3	1.4	0.0	0.7
Illnesses of father: Heart disease	0.8	1.2	2.3	-1.3	-1.3	-1.4	-0.7	0.7	1.5	-0.7	0.5
Illnesses of siblings: Diabetes	0.2	0.2	0.7	-0.2	0.1	0.2	-0.5	-0.8	0.0	0.3	-0.7
Smoking status: Previous	0.3	0.4	0.7	0.7	0.8	0.8	-0.6	-0.4	-0.5	0.4	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.8	-0.5	-0.5	-0.3	0.9	-0.8	0.6	0.4	0.7
Whole body fat-free mass	0.1	0.5	2.4	0.7	0.6	0.4	-0.1	-1.6	-0.1	0.2	0.5
Leg fat-free mass (right)	0.2	0.8	1.8	-0.7	-0.9	-1.0	-0.6	-1.0	1.4	-0.5	0.9
Arm fat percentage (left)	0.4	1.7	3.2	-1.4	-1.8	-1.6	-1.2	-0.7	1.2	-1.5	-0.8
Average weekly red wine intake	0.5	0.8	1.9	-1.2	-0.7	-1.0	-0.6	1.4	0.7	-0.3	0.4
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.9	-0.1	-0.1	-0.4	0.6	-0.4	0.7	0.9	0.6
Mood swings	0.4	0.7	1.5	1.2	0.5	0.2	-0.5	-1.2	0.9	0.4	1.1
Loneliness, isolation	0.5	0.7	2.5	0.5	-0.6	-1.1	0.7	-0.1	1.6	-0.3	-0.8
Long-standing illness, disability or infirmity	0.6	0.9	3.9	-0.9	-0.5	-0.5	-2.0	-0.8	0.3	-0.7	0.7
Ever had bowel cancer screening	0.8	1.0	3.8	-0.1	-0.8	-1.0	0.2	1.5	1.9	-0.1	0.2
Diabetes diagnosed by doctor	0.3	0.4	1.6	0.4	-0.1	0.2	-1.3	-1.2	-0.4	-0.1	0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	3.2	-1.8	-1.2	-1.0	-0.7	0.4	1.2	-1.4	-0.5
Friendships satisfaction	0.6	0.8	3.8	0.6	0.2	0.7	2.0	0.5	0.0	0.1	-1.1
Qualifications: nursing, teaching	0.7	1.0	3.8	-0.5	-0.6	-0.7	-0.1	-0.1	0.9	-1.6	-2.0
Commuting to job workplace: Walk	0.4	0.4	1.2	0.4	-0.6	-0.7	-0.7	-0.2	1.1	0.0	0.6
Eye problems/disorders: Cataract	1.4	1.6	4.1	-2.0	-1.6	-1.8	-0.8	-0.1	1.3	0.2	0.6
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	4.2	-1.4	-1.1	-1.2	-2.1	0.3	0.8	-1.4	0.4
Medication for cholesterol	4.9	7.5	14.7	2.7	3.8	3.8	1.1	-2.2	-3.8	1.6	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.8	1.8	0.6	0.9	1.2	1.3	-0.0	-0.1	-0.1	-1.4
Back pain experienced in last month	1.0	1.5	4.2	-0.4	-0.6	-0.8	-1.2	0.7	0.6	-2.0	-2.1
Mineral and other dietary supplements	0.5	0.7	3.2	-0.0	-0.5	-0.2	0.2	1.8	-0.2	-0.6	-1.2
Breast cancer (self-reported)	0.6	0.7	3.5	-0.4	-0.7	-0.9	-0.3	0.0	1.9	-0.4	0.3
Asthma (self-reported)	2.7	5.3	11.4	2.1	3.4	3.1	-0.3	-1.9	-3.1	2.1	-0.3
Osteoporosis (self-reported)	0.8	1.0	4.8	0.4	0.1	-0.0	1.4	-0.2	0.4	2.2	1.0
Osteoarthritis (self-reported)	0.5	0.7	1.1	-0.9	-0.9	-0.9	-0.8	0.3	0.9	-0.7	-1.1
Medication: Aspirin	2.7	3.5	7.0	-2.6	-2.6	-2.2	-0.9	1.7	1.4	-1.4	-1.1
Medication: Gliclazide	0.8	0.9	3.0	-0.8	-0.8	-0.7	-1.7	0.8	-0.2	-1.4	0.4
Illnesses of father: None of the above (group 1)	5.9	7.3	10.8	2.8	2.9	3.3	3.3	-2.6	-3.0	2.3	-0.4
Smoking status: Current	0.2	0.3	1.1	-1.0	-0.4	-0.4	-0.2	0.0	-0.1	0.5	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.8	5.9	13.8	-2.1	-3.0	-3.2	1.0	3.0	3.7	-0.1	0.3
Whole body water mass	0.1	0.5	2.5	0.7	0.6	0.4	-0.2	-1.6	-0.1	0.1	0.6
Leg predicted mass (right)	0.2	0.8	1.6	-0.6	-0.9	-0.9	-0.6	-1.1	1.3	-0.5	0.9
Arm fat mass (left)	0.2	1.0	1.7	-0.8	-1.3	-1.2	-1.1	-1.1	0.9	-1.1	-0.3
Number of self-reported non-cancer illnesses	2.9	5.0	9.0	-2.0	-2.5	-2.9	-2.9	1.2	3.0	-1.3	-0.8
Average weekly champagne plus white wine intake	0.1	0.1	0.4	-0.5	-0.3	-0.1	0.0	-0.6	-0.1	0.0	0.2
Miserableness	0.3	0.5	1.8	1.4	0.9	0.5	0.4	0.2	0.9	0.5	0.0
Guilty feelings	0.2	0.3	0.7	0.3	0.2	-0.0	-0.5	0.4	0.6	0.8	0.8
Wears glasses or contact lenses	1.2	1.4	7.3	0.8	-0.2	0.2	0.3	1.7	-0.0	-0.3	-2.7
Ever taken oral contraceptive pill	0.4	0.4	1.2	0.3	0.6	1.1	0.1	0.1	-1.1	-0.4	-0.7
Hearing aid user	1.3	1.5	6.1	0.0	0.5	0.8	1.8	1.1	-0.6	-0.5	-2.5
Mother’s age at death	0.9	1.1	2.8	1.0	1.5	1.7	0.3	-1.3	-0.8	0.2	-0.7
Financial situation satisfaction	0.8	0.9	5.6	-0.3	-0.3	-0.4	0.1	-2.4	0.6	-1.1	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.8	0.3	0.5	0.3	-0.4	-0.9	0.1	0.3	-0.5
Commuting to job workplace: Public transport	1.3	1.6	5.4	-0.0	-0.7	-1.3	-0.9	-0.1	2.3	0.3	2.0
Eye problems/disorders: Glaucoma	0.5	0.6	2.6	-0.5	-0.0	0.5	-1.0	-1.6	-0.9	0.4	0.2
Medication: Blood pressure	2.7	5.1	12.9	-2.0	-2.6	-3.0	-1.8	1.8	3.6	-0.7	1.0
Pain type(s) experienced in last month: Hip pain	1.1	1.4	4.9	0.6	0.1	0.5	-2.2	-2.1	-0.9	-0.8	-0.0
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.9	-0.0	0.4	0.4	-0.6	-1.7	-0.0	0.4	1.2
High cholesterol (Self-reported)	2.1	3.8	7.3	-1.7	-2.7	-2.4	-1.5	1.3	2.2	-2.2	-0.6
Medication: Bendroflumethiazide	1.9	2.9	8.4	-1.8	-1.7	-2.1	1.0	1.8	2.9	-0.3	-0.4
Medication: Paracetamol	0.8	1.3	3.7	0.4	-0.0	-0.1	-1.9	-1.6	0.1	0.5	1.9
Medication: Lisinopril	1.2	1.5	3.5	-0.8	-1.9	-1.7	-1.4	-0.3	1.2	-1.1	-0.6
Medication: Atorvastatin	0.6	0.8	1.6	-0.9	-1.3	-1.0	-0.9	-0.8	0.6	-1.0	0.1
Illnesses of father: High blood pressure	2.7	3.3	6.3	-2.0	-1.9	-2.1	-1.8	2.5	1.9	-1.1	0.0
Alcohol drinker status: Never	0.6	0.7	2.0	0.3	0.8	0.5	0.3	-1.1	-0.5	1.4	0.9
Ever smoked	0.3	0.5	1.9	-0.5	-0.1	-0.3	-1.1	1.4	0.4	-0.6	0.3
Basal metabolic rate	0.1	0.4	2.4	0.6	0.5	0.3	-0.0	-1.6	-0.1	0.1	0.4
Leg fat percentage (left)	0.4	1.5	4.3	1.2	1.2	1.1	0.3	-2.1	-1.4	0.5	-1.0
Arm fat-free mass (left)	0.4	2.3	5.6	1.8	1.7	1.5	0.4	-2.4	-1.3	1.2	1.0
Number of operations (self-reported)	5.2	7.7	14.5	-2.9	-3.8	-3.8	-2.1	1.1	3.6	-2.2	0.7
Average weekly beer plus cider intake	0.6	0.9	1.8	-0.7	-1.4	-1.2	-1.2	0.2	0.4	-1.2	-0.3
Irritability	2.2	3.8	9.7	3.1	2.6	2.4	0.4	-1.0	-2.3	0.9	-0.9
Risk taking	2.4	3.5	8.1	2.2	2.4	2.0	0.4	-1.3	-1.9	-0.4	-2.8
Ever had prostate specific antigen (PSA) test	0.4	0.4	1.6	1.2	0.1	-0.0	-0.2	-1.3	0.4	0.0	0.3
Fractured/broken bones in last 5 years	0.5	0.6	2.6	-1.0	0.1	0.3	-0.2	-0.9	0.1	0.4	1.6
Age started oral contraceptive pill	0.5	0.7	2.6	-0.3	-0.6	-0.9	0.2	-0.8	1.6	0.6	0.6
Diastolic blood pressure, automated reading	2.4	7.4	14.3	-2.8	-3.7	-3.8	-2.1	1.8	3.7	-0.8	1.6
Ever depressed for a whole week	0.4	0.5	1.3	0.3	-0.7	-0.7	-0.8	1.1	0.5	-0.8	-0.3
Unable to work because of sickness or disability	0.1	0.2	0.6	0.1	-0.3	-0.3	-0.8	-0.1	0.6	-0.2	0.2
Commuting to job workplace: Cycle	0.6	0.7	1.3	-0.5	-0.8	-0.9	0.7	0.7	1.1	0.4	1.2
Myopia	1.0	1.4	4.7	-0.4	-1.2	-1.7	-0.3	1.2	2.2	-0.6	0.3
Vascular/heart problems diagnosed by doctor	4.0	11.0	22.2	3.7	4.7	4.6	1.9	-2.7	-4.3	1.2	-0.4
Cholesterol lowering medication	4.5	6.6	12.8	-2.5	-3.6	-3.3	-2.2	1.9	3.0	-2.2	0.6
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	4.1	-0.6	-1.0	-1.1	-1.0	-0.7	1.6	-0.3	2.0
Pain experienced in last month	3.3	5.5	10.9	2.5	3.3	3.1	1.4	-1.5	-3.0	1.8	0.4
Supplements: Calcium	0.4	0.4	1.4	0.4	0.3	0.2	-0.0	-1.0	-0.0	1.2	0.9
Basal cell carcinoma (self-reported)	2.1	2.5	6.4	-1.6	-1.9	-1.8	-2.5	-0.7	0.9	-1.6	0.5
Heart attack/myocardial infarction (self-reported)	0.3	0.3	0.8	0.9	-0.3	0.0	0.9	0.3	-0.6	0.6	-0.5
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	3.0	-1.4	-1.7	-1.2	-0.3	0.2	0.9	-1.5	-0.8
Heart disease (siblings)	1.4	1.7	3.1	-1.6	-1.8	-1.7	-1.2	-0.1	1.6	-0.8	0.5
Alcohol drinker status: Previous	0.2	0.2	0.5	-0.2	-0.2	-0.2	0.3	-0.6	0.7	0.7	0.1
Pack years of smoking	3.8	5.6	8.9	-3.0	-3.0	-2.8	-2.6	1.3	2.3	-2.4	0.6
Impedance of whole body	0.3	1.4	4.5	-0.8	-0.5	-0.1	0.3	1.9	-0.5	-1.5	-2.1
Leg fat mass (left)	0.3	1.1	6.0	0.8	0.7	0.7	0.1	-2.5	-0.9	-0.0	-0.8
Arm predicted mass (left)	0.3	1.6	4.5	1.5	1.5	1.3	0.4	-2.1	-1.0	0.9	0.6