Best TWAS P=3.19e-09 · Best GWAS P=4.76e-33 conditioned to 3.34e-36
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | SGCD | 0.26 | 0.09 | enet | 29 | 0.18 | 2.2e-10 | -4.4 | -5.9 | 3.2e-09 | -0.03 | 0.14 | 0.85 | TRUE |
| 2 | GTEx | Artery Tibial | SGCD | 0.12 | 0.03 | lasso | 3 | 0.04 | 7.8e-04 | -5.1 | -5.4 | 6.5e-08 | -0.06 | 0.05 | 0.95 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | LSM11 | 0.05 | 0.00 | blup | 537 | 0.02 | 3.8e-03 | -1.2 | 5.2 | 1.7e-07 | 0.08 | 0.13 | 0.03 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SGCD | 0.07 | 0.04 | lasso | 5 | 0.05 | 1.8e-06 | -5.2 | -5.3 | 9.8e-08 | -0.07 | 0.08 | 0.92 | FALSE |