Best TWAS P=3.71e-11 · Best GWAS P=1.28e-11 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Frontal Cortex BA9 | CPEB4 | 0.39 | 0.00 | lasso | 6 | 0.03 | 5.0e-02 | -5.8 | 5.8 | 5.6e-09 | -0.67 | 0.04 | 0.61 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | CPEB4 | 0.10 | 0.07 | lasso | 2 | 0.06 | 1.3e-08 | -6.8 | 6.3 | 2.8e-10 | -0.97 | 0.00 | 1.00 | FALSE |
3 | YFS | Blood | CPEB4 | 0.58 | 0.72 | bslmm | 632 | 0.73 | 0.0e+00 | -6.8 | -6.6 | 3.7e-11 | 0.99 | 0.00 | 1.00 | TRUE |