Best TWAS P=2.64e-09 · Best GWAS P=2.4e-06 conditioned to 0.171
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | RNF130 | 0.23 | 0.19 | enet | 25 | 0.23 | 4.2e-17 | -2.9 | 5.2 | 2.4e-07 | -0.37 | 0.14 | 0.09 | FALSE |
| 2 | GTEx | Esophagus Mucosa | RNF130 | 0.11 | 0.00 | lasso | 8 | 0.00 | 7.3e-01 | -3.2 | 6.0 | 2.6e-09 | -0.61 | 0.02 | 0.40 | TRUE |