Best TWAS P=3.84e-10 · Best GWAS P=3.16e-11 conditioned to 0.0181
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PHACTR1 | 0.19 | 0.09 | enet | 25 | 0.12 | 5.7e-07 | -6.6 | 5.8 | 5.7e-09 | -0.86 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | RP1-257A7.5 | 0.11 | 0.14 | lasso | 3 | 0.13 | 1.7e-07 | -6.6 | 5.6 | 1.8e-08 | -0.95 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Coronary | RP1-257A7.5 | 0.25 | 0.07 | lasso | 5 | 0.09 | 5.5e-04 | 4.9 | 6.3 | 3.8e-10 | -0.88 | 0.00 | 0.99 | TRUE |
| 4 | GTEx | Artery Tibial | RP1-257A7.5 | 0.16 | 0.10 | enet | 14 | 0.11 | 7.6e-09 | 5.0 | 5.4 | 7.9e-08 | -0.81 | 0.01 | 0.99 | FALSE |