TWAS hub - GOPC

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.12400	0.0310	4.7e-08	0.109	0.070	0.087	0.084	0.093	3.4e-13	6.9e-09	1.1e-10	1.8e-10	2.2e-11
2	GTEx	Artery Aorta	0.10500	0.0360	3.6e-04	0.093	NA	0.118	NA	0.087	7.9e-06	NA	4.7e-07	NA	1.5e-05
3	GTEx	Artery Tibial	0.10940	0.0344	9.2e-05	0.076	NA	0.089	NA	0.093	1.5e-06	NA	1.8e-07	NA	8.9e-08
4	GTEx	Breast Mammary Tissue (Male)	0.04920	0.0745	3.0e-01	0.034	NA	0.054	NA	0.038	5.7e-02	NA	2.2e-02	NA	4.7e-02
5	GTEx	Breast Mammary Tissue (Female)	0.00494	0.0379	4.6e-01	0.010	NA	0.019	NA	0.009	1.5e-01	NA	8.9e-02	NA	1.7e-01
6	GTEx	Nerve Tibial	0.12340	0.0413	4.3e-04	0.058	NA	0.061	NA	0.020	6.3e-05	NA	3.7e-05	NA	1.3e-02
7	GTEx	Thyroid	0.10900	0.0350	3.2e-05	0.015	NA	0.018	NA	0.009	2.2e-02	NA	1.6e-02	NA	6.0e-02
8	ROSMAP	Brain Pre-frontal Cortex	0.12800	0.0275	4.7e-15	0.157	0.134	0.156	0.150	0.155	1.2e-19	7.1e-17	1.5e-19	8.8e-19	2.1e-19
9	TCGA	Breast Invasive Carcinoma	0.01680	0.0086	9.5e-03	0.022	0.010	0.012	NA	0.016	2.2e-05	3.6e-03	1.3e-03	NA	2.1e-04
10	TCGA	Thyroid Carcinoma	0.18500	0.0480	4.6e-12	0.124	0.121	0.109	NA	0.121	4.4e-12	9.1e-12	9.3e-11	NA	8.4e-12

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	6	7	8	9	10
Systolic blood pressure, automated reading	9.7	28.2	59.1	5.1	-5.6	-5.7	-4.7	-6.1	-7.7	5.6	-5.4	-3.9
Systolic Blood Pressure	7.8	39.0	88.4	6.0	-6.4	-6.6	-5.7	-6.5	-9.4	6.6	-6.0	-5.1
Commuting to job workplace: Walk	5.1	5.5	9.2	2.6	-2.4	-3.0	-2.4	-2.4	-2.2	2.8	-2.7	-1.2
Height	4.1	79.2	118.8	10.0	-9.6	-10.9	-6.7	-10.5	-9.9	10.8	-9.3	-5.0
Medication: Ramipril	4.1	5.3	17.7	1.6	-2.3	-2.2	-1.3	-1.9	-4.2	2.5	-2.0	-2.7
Crohns Disease (2012)	4.0	6.4	12.6	-2.5	2.6	3.2	1.1	3.2	3.6	-3.1	2.2	1.6
High blood pressure	4.0	11.2	27.7	2.9	-3.2	-3.6	-2.7	-4.2	-5.3	3.3	-2.9	-3.0
Happiness	4.0	4.9	10.4	-3.0	1.6	3.2	2.6	2.3	0.0	-2.6	2.8	-0.2
Hypertension (Self-reported)	3.9	10.7	27.1	3.1	-3.0	-3.6	-2.8	-4.0	-5.2	3.2	-2.9	-2.5
Bipolar Disorder or Schizophrenia	3.7	9.0	14.5	-2.5	3.4	3.0	3.4	3.5	3.8	-3.1	2.6	2.9
Standing height	3.6	35.3	55.4	7.0	-6.2	-7.4	-4.7	-6.7	-6.7	7.4	-6.1	-2.9
Medication for hormone replacement therapy	3.5	3.9	7.7	-1.3	2.2	2.1	1.5	2.8	2.6	-1.9	1.8	2.0
Comparative height size at age 10	3.5	19.3	34.7	5.9	-4.2	-5.9	-3.1	-4.8	-3.7	5.9	-4.4	-2.2
Medication: Bendroflumethiazide	3.5	5.4	8.4	2.2	-2.9	-2.2	-2.2	-2.9	-2.9	2.3	-2.1	-2.2
Vascular/heart problems diagnosed by doctor	3.5	9.4	27.6	-2.6	3.0	3.1	2.4	3.6	5.3	-2.9	2.5	2.8
Stomach or abdominal pain in last month	3.3	4.1	6.4	-1.7	2.3	1.8	2.4	2.4	2.5	-2.2	2.5	1.0
Illnesses of mother	3.2	3.9	6.1	-2.0	2.5	2.3	2.4	2.2	1.8	-2.1	2.1	1.0
Bipolar Disorder (2018)	3.1	5.0	12.3	-2.2	2.4	2.3	1.7	1.6	2.4	-2.7	1.6	3.5
Pack years adult smoking proportion	3.1	4.8	10.3	2.1	-1.9	-2.7	-2.7	-2.5	-1.6	2.4	-3.2	0.8
Medication: Aspirin	3.0	3.9	17.7	0.8	-2.2	-1.2	-1.8	-1.7	-4.2	1.1	-1.4	-2.2
Forced expiratory volume in 1-second (FEV1), predicted	3.0	6.1	11.5	3.1	-2.2	-3.4	-2.6	-2.6	-2.4	3.1	-2.3	-1.0
Crohns Disease (2017)	2.9	6.3	11.9	-2.7	2.7	2.9	0.2	2.8	2.9	-3.2	1.4	3.5
Type 2 Diabetes (T2D) (2018)	2.9	5.4	9.6	2.6	-2.6	-2.7	-2.4	-3.1	-1.7	2.5	-3.0	-0.5
Eye problems/disorders: Diabetes related eye disease	2.9	3.2	5.2	2.1	-2.0	-2.1	-1.6	-1.6	-1.7	2.3	-1.7	-1.6
Medication for cholesterol, blood pressure or diabetes	2.9	4.8	10.9	-1.2	2.3	1.9	2.8	2.5	3.3	-1.8	2.1	2.2
Commuting to job workplace: Car/motor vehicle	2.9	3.4	7.9	-1.3	2.4	1.8	0.6	2.5	2.8	-2.0	1.3	1.7
Pack years of smoking	2.9	4.3	8.9	1.9	-1.7	-2.5	-2.9	-2.4	-1.2	2.1	-3.0	1.0
Sitting height	2.8	19.7	46.1	4.2	-4.8	-4.9	-3.9	-4.6	-6.8	4.8	-4.7	-2.1
Forced expiratory volume in 1-second (FEV1)	2.8	9.5	18.7	3.3	-2.9	-3.4	-2.0	-3.0	-4.3	3.9	-2.1	-3.5
High cholesterol (Self-reported)	2.7	4.7	7.8	2.4	-2.1	-2.5	-2.8	-2.5	-2.4	2.2	-2.2	-1.1
Ever unenthusiastic/disinterested for a whole week	2.6	3.1	5.3	-0.9	2.2	1.8	2.2	1.9	1.7	-1.8	2.3	1.7
Medication: Aspirin	2.6	3.4	13.8	0.9	-2.0	-1.3	-1.8	-1.7	-3.7	1.1	-1.5	-1.9
Medication: Omeprazole (e.g. Zanprol)	2.6	3.2	6.1	-2.2	2.0	1.9	0.6	1.5	1.5	-2.5	1.7	2.3
Pulse wave reflection index	2.5	3.1	4.9	-1.8	2.0	2.2	1.8	2.1	0.4	-2.1	2.0	1.5
Waist Hip Ratio (WHR)	2.4	10.9	19.7	4.2	-3.2	-4.4	-2.3	-3.5	-2.6	4.2	-4.4	-1.0
Lung cancer (father)	2.4	2.8	9.1	0.7	-2.0	-1.6	-1.2	-3.0	-0.9	1.7	-2.3	-0.7
Ever had bowel cancer screening	2.4	2.8	4.4	-1.9	2.1	2.0	1.2	1.9	1.5	-2.1	1.8	0.8
Schizophrenia (2018)	2.3	4.8	10.0	-1.4	2.4	2.1	2.9	3.2	3.0	-1.8	2.1	0.8
Neuroticism (2016)	2.3	3.3	6.9	0.4	2.6	0.8	2.0	2.6	2.2	-1.0	2.3	1.9
Lung FEV1/FVC ratio	2.3	11.8	35.0	2.2	-3.5	-2.8	-1.2	-3.8	-5.2	3.5	-1.8	-5.9
Diabetes (mother)	2.3	2.9	5.9	2.4	-1.1	-2.1	-1.4	-2.3	-1.2	1.9	-2.2	0.8
Medication: Blood pressure	2.3	4.1	8.9	1.5	-1.7	-2.1	-2.2	-2.5	-3.0	1.8	-2.0	-1.9
Irritable Bowel Disease (IBD)	2.2	5.3	15.6	-2.2	2.5	2.5	-0.7	1.9	2.7	-2.8	0.7	3.9
Supplements: Zinc	2.2	2.4	4.8	1.3	-1.5	-2.0	-1.7	-1.6	-1.1	1.9	-2.2	-1.0
Medication: Simvastatin	2.2	3.2	8.2	1.1	-1.8	-1.8	-2.2	-1.9	-2.9	1.6	-1.4	-1.7
Cardiovascular Disease	2.1	6.9	23.4	2.0	-2.5	-2.5	-3.0	-2.8	-4.8	2.2	-2.3	-1.5
Chronotype (morning person)	2.1	4.8	9.7	2.1	-2.6	-2.4	-2.3	-1.0	-2.7	2.1	-1.8	-3.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.8	13.8	2.7	-2.4	-3.0	-1.6	-2.5	-3.7	3.3	-1.5	-3.2
Medication: Ventolin 100micrograms inhaler	2.1	2.7	8.2	-2.2	1.5	1.5	1.3	1.1	1.4	-1.9	0.9	2.9
Commuting to job workplace: Public transport	2.1	2.5	7.5	0.6	-2.0	-1.1	-0.5	-1.6	-2.7	1.5	-1.1	-2.5
Lupus	2.0	3.0	6.1	-1.1	2.1	1.2	2.5	1.8	2.0	-1.5	1.8	2.1
Average weekly fortified wine intake	1.9	2.2	6.0	0.6	-2.1	-1.5	-1.3	-2.4	-0.9	1.5	-2.0	-0.6
High blood pressure (mother)	1.9	2.6	7.7	1.1	-1.8	-1.6	-2.8	-1.4	-1.4	1.3	-2.4	-0.5
Hair/balding pattern: Pattern 2	1.9	2.4	4.3	-1.1	1.5	1.6	1.3	1.4	1.7	-2.1	1.6	2.1
Peak expiratory flow (PEF)	1.9	4.5	12.2	2.2	-1.5	-2.3	-1.9	-1.7	-3.5	2.5	-1.0	-2.6
Medication: Amlodipine	1.9	2.7	4.7	1.6	-1.6	-1.7	-2.0	-2.1	-2.2	1.6	-1.3	-1.0
Diabetes diagnosed by doctor	1.9	3.2	5.8	1.9	-2.2	-2.0	-1.8	-2.4	-1.7	1.9	-1.9	-0.5
Risk taking	1.9	2.7	5.2	-1.6	1.9	1.7	1.3	2.1	2.3	-1.7	1.9	1.0
Major Depression (MDD)	1.8	2.1	5.6	-0.5	1.6	1.1	2.4	1.8	0.9	-1.3	2.2	1.2
Frequency of depressed mood in last 2 weeks	1.8	2.5	6.0	-0.8	2.0	1.4	2.4	1.9	1.1	-1.2	2.4	0.8
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.0	7.2	-2.0	1.9	2.7	1.7	2.3	1.8	-2.7	2.6	0.2
Heart attack	1.8	2.3	4.0	-1.0	1.9	1.6	1.4	1.9	-0.4	-1.7	2.0	1.7
Trunk fat-free mass	1.8	10.2	17.1	3.8	-3.4	-4.1	-2.6	-3.8	-3.3	3.7	-3.6	0.4
Emphysema/chronic bronchitis	1.8	2.0	3.3	1.5	-1.7	-1.8	-1.6	-1.2	-1.3	1.8	-1.5	-1.0
Chest pain or discomfort	1.8	2.7	10.4	-1.0	1.7	1.4	0.7	1.7	1.7	-1.7	0.9	3.2
Number of operations (self-reported)	1.8	2.7	4.5	1.6	-1.7	-1.9	-2.1	-1.4	-2.1	1.6	-2.1	-0.3
Trunk predicted mass	1.7	9.5	15.9	3.6	-3.3	-4.0	-2.5	-3.7	-3.3	3.5	-3.5	0.4
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	4.5	2.0	-1.6	-1.5	-0.8	-1.7	-0.6	1.5	-0.9	-2.1
Medication: Blood pressure	1.7	3.3	14.7	1.2	-1.8	-1.4	-1.3	-1.8	-3.8	1.4	-1.1	-1.9
Heart attack/myocardial infarction (self-reported)	1.7	2.2	3.7	-1.1	1.8	1.6	1.2	1.9	-0.1	-1.8	1.9	1.8
Bipolar Disorder (2011)	1.6	1.5	3.3	-1.6	1.2	1.2	0.0	0.6	1.8	-1.3	1.1	1.7
Rheumatoid Arthritis	1.6	2.2	4.1	1.9	-1.4	-1.7	-2.0	-1.4	-0.5	1.7	-2.0	0.3
Diabetes (father)	1.6	2.0	4.2	1.1	-1.9	-1.3	-1.6	-1.5	-1.2	1.5	-2.1	-0.7
Medication: Allopurinol	1.6	2.1	4.2	-1.0	2.0	1.6	0.8	1.1	2.1	-1.7	1.6	1.2
Had major operations	1.6	1.9	5.2	1.3	-1.3	-1.5	-2.3	-1.5	-0.6	1.2	-1.9	0.3
Depression (Nagel 2018)	1.5	2.2	3.7	-1.4	1.9	1.7	1.9	1.7	1.0	-1.5	1.4	1.3
Forced vital capacity (FVC)	1.5	5.8	10.1	2.9	-2.4	-2.9	-1.9	-2.3	-3.1	3.2	-1.9	-1.6
Diabetes (self-reported)	1.5	2.3	4.2	1.6	-2.1	-1.8	-0.8	-1.9	-1.7	1.6	-1.4	-1.1
Medication: Cholesterol lowering	1.5	2.3	7.2	0.6	-1.4	-1.2	-2.7	-1.6	-2.2	1.1	-1.3	-1.4
Shortness of breath walking on level ground	1.5	1.8	3.5	-1.9	1.6	1.4	1.1	0.4	1.1	-1.7	1.3	1.6
Forced vital capacity (FVC), Best measure	1.4	5.0	8.9	2.5	-2.2	-2.7	-1.9	-2.1	-3.0	2.9	-1.7	-1.8
Age at first live birth	1.4	2.4	7.0	-1.2	1.5	1.6	1.8	2.6	1.7	-1.3	1.7	0.5
Pulse wave peak to peak time	1.4	1.6	2.8	1.6	-1.4	-1.6	-0.9	-1.4	0.5	1.7	-1.5	-1.1
Qualifications: College or University degree	1.4	4.4	11.0	-1.9	1.6	2.3	1.7	2.1	2.6	-2.2	1.6	3.3
Handedness (chirality/laterality): Left-handed	1.4	1.7	3.8	-1.6	1.6	1.2	0.6	1.2	1.3	-1.5	1.0	2.0
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	6.3	-0.9	2.0	0.8	1.2	1.4	2.5	-1.2	1.3	1.8
Mother’s age at death	1.4	1.8	3.6	-1.1	1.8	1.4	0.9	1.9	1.1	-1.4	0.9	1.7
Fractured/broken bones in last 5 years	1.4	1.8	4.3	0.8	-1.8	-1.3	-0.5	-2.1	-1.4	1.5	-1.3	-1.4
Schizophrenia vs Biploar Disorder	1.3	1.7	8.6	0.8	-1.5	-0.7	-0.2	-0.3	-1.8	1.2	-0.6	-2.9
Ulcerative Colitis (UC)	1.3	2.3	8.4	-1.0	1.8	1.6	-0.6	0.9	2.0	-1.8	0.4	2.9
Breast Cancer	1.3	3.1	6.0	-1.9	1.2	2.4	2.0	2.4	0.9	-2.2	2.2	-0.0
Ulcerative Colitis	1.3	1.9	5.0	-1.3	1.6	1.5	-0.3	0.7	2.1	-1.7	0.4	2.2
Mouth/teeth dental problems	1.3	2.0	5.4	1.9	-1.2	-1.4	0.9	-1.5	-0.8	2.0	-0.2	-2.3
Gout (self-reported)	1.3	1.8	3.6	-0.8	1.7	1.6	0.9	1.8	1.0	-1.7	1.9	0.3
Medication: Omeprazole	1.3	1.6	3.9	-1.7	1.1	1.3	-0.4	1.0	0.9	-1.8	1.0	2.0
Whole body fat-free mass	1.3	7.3	12.3	3.1	-2.8	-3.5	-2.1	-3.3	-3.1	3.0	-3.0	0.7
Whole body water mass	1.3	7.3	12.4	3.1	-2.8	-3.5	-2.1	-3.3	-3.2	3.0	-3.0	0.6
Miserableness	1.3	2.3	6.4	-1.7	1.6	1.8	1.3	2.5	1.0	-1.7	1.5	0.6
Alzheimer’s Disease (in mother)	1.2	1.4	2.6	1.4	-1.2	-1.5	0.4	-1.3	-1.2	1.6	-0.4	-1.5
LDL Cholesterol	1.2	1.9	4.2	1.2	-1.6	-1.4	-1.9	-2.0	-0.8	1.3	-1.2	-1.2
Schizophrenia (2014)	1.2	2.7	6.2	-1.3	1.7	1.8	2.3	2.5	2.0	-1.4	1.2	0.7
Age when periods started (menarche)	1.2	2.9	7.6	0.8	-2.8	-1.3	-1.3	-2.1	-2.5	1.4	-1.6	-1.6
Blood clot in the leg (DVT)	1.2	1.6	4.8	0.4	-1.0	-1.2	-1.6	-1.7	-2.2	0.9	-1.1	-1.1
High blood pressure (siblings)	1.2	1.8	7.6	0.8	-1.5	-0.7	-0.9	-1.9	-2.8	0.6	-0.7	-1.2
Alcohol intake frequency.	1.2	2.7	6.0	-1.1	2.3	1.2	0.1	2.1	2.4	-1.6	1.0	2.3
Basal metabolic rate	1.2	6.7	11.6	3.0	-2.5	-3.4	-2.0	-3.2	-3.1	2.9	-2.8	0.6
Diastolic blood pressure, automated reading	1.2	3.8	16.1	1.5	-1.9	-1.4	-1.5	-1.9	-4.0	1.4	-1.1	-2.2
Number of treatments/medications taken	1.1	2.1	7.8	1.2	-0.9	-1.4	-1.7	-1.8	-2.8	1.0	-1.1	0.2
Ever used hormone-replacement therapy (HRT)	1.1	1.4	3.4	0.3	1.8	0.5	1.3	1.1	1.5	-0.7	1.3	1.8
Severe depression (siblings)	1.1	1.2	2.4	-1.3	1.1	0.9	-1.6	0.9	1.4	-1.2	0.6	1.1
Leg fat-free mass (left)	1.1	5.7	10.8	2.7	-2.3	-3.1	-1.7	-2.9	-3.3	2.6	-2.4	0.3
Fed-up feelings	1.1	1.9	4.2	-0.7	1.6	1.3	2.0	2.0	0.9	-1.3	1.8	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	3.3	-0.8	1.8	1.0	1.3	1.1	0.8	-1.1	1.2	1.8
Leg predicted mass (left)	1.1	5.7	10.6	2.7	-2.3	-3.0	-1.8	-2.9	-3.3	2.6	-2.4	0.3
Fluid intelligence score	1.1	2.2	5.6	0.8	-2.1	-1.4	-1.7	-1.0	-2.4	1.3	-1.9	-0.3
Alcohol intake versus 10 years previously	1.1	1.7	3.1	-1.4	1.8	1.2	1.1	1.6	1.4	-1.3	0.9	1.5
Ever highly irritable/argumentative for 2 days	1.1	1.3	3.3	-1.8	1.3	1.3	0.8	0.3	1.4	-1.3	0.7	1.1
Eye problems/disorders: None of the above	1.1	1.3	5.8	-1.2	0.5	1.5	-0.5	0.3	0.2	-1.6	-0.2	2.4
Leg predicted mass (right)	1.1	5.8	12.4	2.6	-2.4	-3.1	-1.8	-2.8	-3.5	2.6	-2.5	0.3
Number of self-reported non-cancer illnesses	1.1	1.9	5.2	1.4	-1.0	-1.5	-1.4	-2.3	-1.8	1.2	-1.4	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	4.2	-1.5	1.5	2.0	1.7	1.5	1.4	-2.0	1.7	0.5
Time employed in main current job	1.0	1.2	5.0	-0.1	-1.4	-0.2	-0.2	-0.3	-1.9	0.3	-0.9	-2.2
Falls in the last year	1.0	1.4	3.1	1.5	-1.0	-1.7	-0.9	-1.8	-0.9	1.2	-1.3	0.2
Asthma	1.0	1.9	3.7	-1.9	0.9	1.8	1.7	1.4	0.5	-1.9	0.9	1.5
Headache pain in last month	1.0	1.7	3.4	-1.1	1.8	1.2	1.8	1.4	0.8	-1.5	1.6	0.7
Health satisfaction	1.0	1.3	3.2	0.8	-1.5	-0.9	-1.3	-1.8	-1.4	0.8	-1.4	-0.0
Pulse rate, automated reading	1.0	3.2	7.4	2.7	-1.5	-2.5	-0.7	-1.3	-1.1	2.1	-0.8	-2.6
Illness, injury, bereavement, stress in last 2 years	1.0	1.3	3.3	0.5	-0.9	-1.2	-0.8	-1.2	-1.8	1.2	-1.4	-1.3
Illnesses of father: Heart disease	1.0	1.4	3.1	-1.8	1.5	1.4	0.6	1.6	0.3	-1.4	1.0	0.8
Leg fat-free mass (right)	1.0	5.6	11.7	2.6	-2.3	-3.0	-1.8	-2.7	-3.4	2.5	-2.5	0.4
Illnesses of father: None of the above (group 1)	1.0	1.3	2.5	1.3	-1.2	-1.3	-0.7	-1.6	0.4	1.5	-1.0	-1.2
Tinnitus: Yes, now most or all of the time	1.0	1.2	2.9	1.7	-1.0	-1.4	0.4	-1.7	-0.4	1.4	-0.7	-0.7
Alcohol drinker status: Never	1.0	1.2	2.2	-1.4	1.0	1.5	0.2	1.2	1.2	-1.5	0.9	0.8
Verbal and Numeric Reasoning (VNR)	0.9	2.1	7.3	0.5	-2.1	-1.1	-1.6	-1.3	-2.7	1.2	-1.5	-0.5
Age at First Birth	0.9	1.3	3.5	-1.1	0.7	1.5	1.9	1.5	1.3	-1.1	0.6	-0.1
Primary Biliary Cirrhosis	0.9	1.3	6.6	-0.7	0.9	0.5	-0.4	1.1	1.5	-1.1	-0.5	2.6
Hayfever, allergic rhinitis or eczema	0.9	2.0	5.1	-1.7	1.6	1.5	0.7	1.7	0.7	-1.6	1.0	2.3
Weight	0.9	4.3	7.8	2.6	-1.6	-2.8	-1.1	-2.8	-2.8	2.2	-2.0	0.4
Impedance of arm (right)	0.9	4.1	8.4	2.3	-1.8	-1.9	-1.5	-2.0	-2.5	2.5	-1.3	-2.9
Pulse rate	0.9	1.5	6.5	0.2	-1.5	-0.9	-1.6	-0.5	-1.1	0.8	-0.7	-2.5
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	3.0	-0.4	1.0	0.9	0.5	1.7	1.7	-1.0	1.3	-0.4
Prospective memory result	0.9	1.1	1.9	-1.4	1.0	1.2	0.6	1.4	1.1	-1.3	1.2	-0.1
Worry too long after embarrassment	0.9	1.5	3.9	-1.4	1.1	1.5	0.9	2.0	1.1	-1.2	1.6	-0.1
Neck or shoulder pain in last month	0.9	1.2	6.7	-0.3	1.3	0.5	-0.8	0.4	1.1	-1.1	0.4	2.6
Angina (self-reported)	0.9	1.2	3.2	0.6	-0.6	-1.1	-1.4	-0.8	-1.8	0.5	-1.0	1.7
Qualifications: nursing, teaching	0.9	1.4	2.8	-0.8	1.1	1.4	1.5	1.4	1.5	-0.9	1.7	0.2
Eye problems/disorders: Cataract	0.9	1.1	2.9	-1.0	0.7	0.6	1.7	0.9	1.0	-0.5	1.5	-1.4
Arm fat-free mass (left)	0.9	4.3	7.9	2.2	-1.9	-2.8	-1.6	-2.6	-2.2	2.2	-2.5	1.1
Arm predicted mass (left)	0.9	4.4	7.9	2.2	-2.0	-2.8	-1.6	-2.6	-2.3	2.1	-2.5	1.1
Depressed Affect (Nagel 2018)	0.8	1.7	3.9	-1.6	1.3	1.7	1.0	2.0	0.5	-1.6	1.3	0.7
Alzheimer’s Disease (including proxy)	0.8	1.1	3.2	1.8	-0.5	-1.6	0.5	-0.9	-1.3	1.5	-0.3	-0.5
Ovarian Cancer	0.8	1.0	3.0	-1.7	0.9	1.4	0.7	0.8	-0.0	-1.5	0.9	0.4
HbA1C	0.8	0.9	2.1	1.0	-0.9	-1.1	-0.7	-1.2	-0.8	1.0	-1.5	0.2
HDL Cholesterol	0.8	1.3	3.7	1.9	-1.1	-1.8	0.1	-0.4	-0.4	1.9	-0.7	-0.6
Triglycerides	0.8	1.2	3.4	1.5	-0.5	-1.3	-1.8	-1.2	0.1	0.9	-1.3	0.9
Heel T-Score	0.8	6.7	14.1	-3.2	2.2	3.8	2.2	3.5	0.9	-3.5	2.7	-0.5
Allergy or Eczema	0.8	2.0	8.8	-1.5	1.6	1.1	0.5	1.6	0.6	-1.4	0.2	3.0
Neuroticism	0.8	2.0	4.6	-1.4	1.9	1.6	1.4	2.1	0.5	-1.3	1.8	0.5
Angina	0.8	1.0	4.0	0.6	-0.6	-1.1	-0.9	-0.7	-2.0	0.6	-0.8	1.3
Medication: Metformin	0.8	1.1	2.2	1.0	-1.1	-1.4	-1.0	-1.5	-1.0	1.1	-1.3	-0.0
Maternal smoking around birth	0.8	1.1	4.4	0.2	-1.1	-1.0	-1.3	-2.1	-1.0	0.6	-1.0	-0.6
Taking other prescription medications	0.8	1.3	4.3	1.0	-0.9	-1.4	-0.9	-2.1	-1.1	1.1	-1.2	0.3
Past tobacco smoking	0.8	1.5	2.5	-1.4	1.5	1.6	0.9	1.4	1.4	-1.1	1.4	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.4	2.3	-1.1	1.1	1.4	1.3	1.4	0.2	-1.2	1.3	1.5
Exposure to tobacco smoke at home	0.8	0.9	1.8	-1.1	1.3	1.1	0.4	1.0	1.4	-1.0	0.8	0.4
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	2.9	-1.7	0.4	1.2	-0.8	0.7	-0.3	-1.4	-0.4	1.5
Smoking status: Previous	0.8	1.2	2.0	1.4	-0.9	-1.4	-1.0	-0.9	-1.2	1.1	-1.4	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	6.3	-0.5	1.0	0.6	-0.7	0.0	0.7	-1.0	0.1	2.5
Back pain experienced in last month	0.8	1.1	3.0	-1.7	0.7	1.4	0.6	0.7	0.1	-1.6	0.9	1.4
Mineral and other dietary supplements	0.8	1.0	4.6	2.1	-0.4	-1.6	0.2	-0.2	-0.6	1.6	-0.4	0.0
Asthma (self-reported)	0.8	1.6	3.5	-1.9	0.7	1.7	1.5	1.1	0.1	-1.7	0.8	1.4
Hearing aid user	0.8	0.9	3.4	1.8	-0.3	-1.4	0.2	-1.1	0.1	1.2	-0.7	0.5
Irritability	0.8	1.4	6.9	0.0	0.8	0.7	2.6	1.5	-0.3	-0.4	1.7	-0.1
Ever depressed for a whole week	0.8	1.0	2.4	-1.2	1.0	1.4	-0.6	0.7	0.6	-1.5	0.8	1.1
Neuroticism (Nagel 2018)	0.7	1.6	3.8	-0.9	1.5	1.3	1.1	1.9	1.4	-1.2	1.2	1.3
Alzheimer’s Disease (in father)	0.7	0.7	1.9	1.4	-0.1	-1.1	-0.7	-0.2	-0.5	1.0	-1.3	1.0
Blood Red Count	0.7	6.6	22.3	1.6	-2.6	-2.5	-1.2	-2.4	-3.0	2.7	-2.1	-4.7
Medication: Co-codamol	0.7	0.8	2.5	0.1	1.0	0.5	1.6	0.7	1.3	-0.5	1.3	-0.3
Hearing difficulty/problems with background noise	0.7	1.1	3.1	-0.5	1.3	0.8	1.8	1.0	0.6	-0.8	0.7	1.7
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.7	-0.8	-0.3	0.1	-1.1	-0.5	-1.4	-0.2	-1.1	1.9
Hair/balding pattern: Pattern 3	0.7	1.1	4.6	-0.0	-0.6	-0.5	0.1	-0.9	-2.0	0.9	-0.3	-2.1
Pulse wave Arterial Stiffness index	0.7	0.8	1.2	-0.9	0.9	1.0	0.5	0.8	-1.1	-1.1	1.0	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	2.5	0.0	1.4	0.5	0.7	1.6	-0.2	-0.9	1.6	1.5
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	3.7	0.7	-1.9	-0.8	-1.1	-1.0	-0.7	1.1	-1.6	-0.7
Wheeze or whistling in the chest in last year	0.7	1.2	8.0	-0.9	0.2	0.5	-0.2	0.2	0.4	-0.9	-1.2	2.8
Number of children fathered	0.7	0.8	2.0	0.7	-0.8	-1.1	1.3	-0.6	-0.5	1.1	-0.1	-1.4
Number of full sisters	0.7	0.8	1.6	0.8	-1.0	-0.6	-1.0	-1.3	-1.2	0.7	-1.3	-0.7
Leg pain on walking	0.7	0.9	3.7	-1.3	0.5	0.9	0.1	0.3	0.6	-1.2	0.2	1.9
Illnesses of siblings: Diabetes	0.7	0.8	2.4	-1.6	0.5	1.2	0.1	-0.2	0.0	-1.5	0.6	1.2
Commuting to job workplace: Cycle	0.7	0.8	2.2	0.7	-0.9	-0.7	-1.3	-0.5	-1.5	0.8	-0.4	-1.2
Reaction Time	0.6	1.1	2.4	-0.8	1.4	0.8	1.6	1.1	0.7	-0.6	1.5	-1.1
Fasting Glucose	0.6	0.7	2.1	0.7	-0.7	-1.1	0.6	-0.8	-1.4	0.9	-0.5	-0.8
Respiratory disease	0.6	1.3	3.3	-1.6	0.8	1.4	0.9	1.0	0.9	-1.3	0.3	1.8
Waist circumference	0.6	2.4	4.7	2.1	-0.9	-2.2	-0.7	-2.0	-1.7	1.5	-1.8	1.1
Neuroticism score	0.6	1.2	3.5	-0.7	1.4	1.0	1.3	1.9	0.7	-0.8	1.6	0.2
Exposure to tobacco smoke outside home	0.6	0.8	2.1	-1.4	1.2	1.1	-0.1	0.4	1.4	-1.1	0.4	0.5
Comparative body size at age 10	0.6	1.6	4.1	-1.1	1.4	1.1	1.6	0.9	2.0	-1.0	1.0	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.6	0.3	1.1	0.8	1.2	1.6	0.5	-0.6	1.0	0.6
Migraine (self-reported)	0.6	0.7	2.7	-0.4	1.1	0.4	0.1	-0.1	1.1	-0.8	0.9	1.6
Heart disease (mother)	0.6	0.7	2.8	-0.8	0.4	0.8	0.8	0.8	0.7	-1.0	1.7	-0.1
Mood swings	0.6	1.1	2.9	-0.3	1.3	0.8	1.6	1.7	0.5	-0.7	1.7	0.2
Loneliness, isolation	0.6	0.8	1.8	-1.3	0.8	1.3	-0.2	1.1	0.1	-1.0	1.1	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.2	-0.6	1.0	0.6	1.5	0.9	1.1	-0.4	0.5	-0.0
Friendships satisfaction	0.6	0.8	2.3	-1.5	0.3	1.5	-0.1	0.7	0.1	-1.3	0.1	0.9
Guilty feelings	0.6	0.9	2.9	-0.5	1.0	0.5	1.3	1.1	1.7	-0.4	1.2	-0.5
Wears glasses or contact lenses	0.6	0.7	2.2	0.9	-0.6	-1.1	-0.4	-1.5	-1.0	0.8	-0.8	0.3
Eye problems/disorders: Glaucoma	0.6	0.7	2.1	-0.2	1.2	0.2	0.7	1.4	0.2	-0.6	1.5	0.5
Medication: Lisinopril	0.6	0.8	3.8	0.6	0.2	-0.9	-1.9	-0.3	-0.8	0.2	-1.0	1.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.9	-0.3	-1.3	-0.5	-0.6	-1.1	-0.7	0.5	-1.1	-1.4
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	3.2	0.0	-0.5	-0.7	-1.1	-1.0	-1.8	0.4	-0.6	-0.7
Intelligence (Savage-Jansen 2018)	0.5	1.5	6.9	0.2	-1.9	-0.8	-0.5	-1.4	-2.6	1.0	-1.0	0.2
Body Mass Index (BMI) (2010)	0.5	0.7	5.3	-0.3	0.7	0.2	0.6	0.1	0.2	-0.5	-0.2	2.3
Coronary Artery Disease (CAD)	0.5	0.6	1.4	-0.9	0.6	1.2	0.8	0.7	0.6	-1.0	0.7	0.4
Average weekly spirits intake	0.5	0.6	1.8	0.5	-0.1	-0.8	0.1	-1.3	0.7	0.7	-0.9	1.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.3	0.9	-0.6	-1.1	-0.9	-0.8	0.5	0.8	-1.1	0.4
Chronic bronchitis/emphysema (father)	0.5	0.5	2.9	-0.7	0.7	0.6	-0.4	0.0	-0.2	-0.9	0.1	1.7
Trunk fat mass	0.5	2.0	4.3	2.1	-0.4	-2.1	-0.4	-2.1	-1.9	1.4	-0.9	0.3
Financial difficulties in last 2 years	0.5	0.7	1.8	-0.6	1.2	0.7	1.1	0.6	0.5	-0.8	0.6	1.3
Illnesses of siblings	0.5	0.7	4.9	0.2	0.8	-0.2	0.7	1.0	2.2	0.4	0.3	-0.2
Medication: Lansoprazole	0.5	0.5	1.9	-0.4	0.5	0.6	1.0	0.7	-0.8	-0.7	1.4	0.1
Impedance of arm (left)	0.5	2.4	7.6	1.8	-1.1	-1.3	-0.9	-1.1	-2.1	1.8	-0.5	-2.8
Tense / ‘highly strung’	0.5	0.9	2.0	-0.3	1.3	0.4	1.4	1.3	1.2	-0.6	1.2	0.2
Arm fat-free mass (right)	0.5	2.6	4.7	1.6	-1.5	-2.2	-1.3	-2.0	-1.7	1.4	-1.9	1.4
Number of full brothers	0.5	0.6	1.8	1.3	-0.7	-0.9	0.1	-0.4	-1.1	1.0	-0.1	-0.9
Medication: Ibuprofen	0.5	0.5	1.8	1.3	-0.4	-0.8	-0.6	-0.8	-0.2	0.7	-0.6	1.0
Mean time to correctly identify matches	0.5	1.0	2.2	-0.8	1.2	0.8	1.3	1.1	0.4	-0.7	1.5	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.9	-0.8	0.6	0.6	0.2	0.8	-0.8	-0.7	1.4	-0.9
Arm predicted mass (right)	0.5	2.4	4.3	1.6	-1.3	-2.1	-1.2	-1.9	-1.8	1.4	-1.8	1.4
Myopia	0.5	0.7	1.8	-0.6	-1.1	0.2	-1.2	-0.9	-1.0	-0.1	-1.3	0.3
Blood Platelet Count	0.4	4.1	7.7	-0.9	2.6	1.8	1.9	2.8	2.3	-1.8	2.1	2.3
Hypothyroidism (self reported)	0.4	0.8	3.2	-0.1	1.3	0.6	0.6	0.6	1.0	-0.9	0.7	1.8
Vitamin and mineral supplements	0.4	0.5	1.0	0.4	0.9	0.5	0.9	0.7	1.0	-0.4	1.0	0.5
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.3	-0.3	-1.2	-0.3	-1.1	0.0	-0.6	0.4	-0.9	-0.1
Multivitamins +/- minerals	0.4	0.5	1.7	-1.0	-0.5	-0.0	-1.3	-0.8	-0.3	0.0	-1.0	-0.1
Medication: Atenolol	0.4	0.6	1.9	-0.4	1.3	0.4	0.0	0.2	0.3	-0.8	0.9	1.4
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	3.1	0.6	0.7	-0.2	1.8	0.8	-1.0	0.4	0.9	-0.6
Father’s age at death	0.4	0.6	3.6	0.4	0.6	0.2	1.9	0.6	0.8	-0.1	0.9	0.0
Worrier / anxious feelings	0.4	0.8	1.7	-1.0	1.3	0.8	0.5	1.3	0.4	-0.9	0.9	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.5	1.6	-0.2	-0.9	-0.3	-0.5	-0.3	0.7	-0.3	0.9
Arm fat mass (right)	0.4	1.6	3.4	1.8	-0.4	-1.8	-0.7	-1.8	-1.7	1.1	-1.0	0.8
Birth weight of first child	0.4	0.8	5.2	-0.3	0.6	0.7	0.5	0.5	2.3	-0.7	0.5	0.6
Glaucoma (self-reported)	0.4	0.5	1.3	0.0	1.0	0.2	-0.0	1.1	-0.0	-0.6	1.1	0.9
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.4	-1.2	-0.1	0.7	-0.6	-0.8	-0.1	-0.9	0.7	-0.3
Suffer from ‘nerves’	0.4	0.7	1.7	-0.5	1.3	0.8	-0.2	0.9	0.6	-1.0	1.2	0.7
Age at last live birth	0.4	0.6	2.0	-0.4	0.6	0.5	1.0	1.3	1.4	-0.5	0.5	0.3
Family relationship satisfaction	0.4	0.5	1.6	-1.3	-0.2	1.3	0.6	0.3	-0.3	-0.9	0.5	-0.4
Osteoporosis (self-reported)	0.4	0.5	1.6	-1.3	0.7	0.9	0.6	0.9	0.6	-0.8	0.2	0.5
Osteoarthritis (self-reported)	0.4	0.6	2.8	1.7	-0.3	-1.0	-0.3	-0.8	-0.3	0.8	-0.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	5.8	0.2	-0.2	-0.3	0.6	-0.3	-0.9	0.7	0.9	-2.4
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.1	0.3	-0.3	-0.7	-1.0	-1.1	-0.3	0.6	-1.0	0.9
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.0	-1.4	-0.1	1.1	-0.4	-0.2	0.1	-1.0	0.0	-0.5
Medication: Paracetamol	0.4	0.6	3.1	0.5	0.3	-0.2	-0.3	-1.4	-0.7	-0.2	-0.0	1.8
Medication: Atorvastatin	0.4	0.5	2.7	-0.4	-1.0	0.2	0.2	-0.1	-1.6	0.2	0.0	-0.9
Leg fat percentage (left)	0.4	1.6	4.3	-0.7	2.1	0.9	1.4	0.7	1.0	-1.5	1.4	1.5
Average weekly beer plus cider intake	0.4	0.6	1.2	0.6	-0.6	-1.1	-0.8	-1.1	-1.0	0.9	-0.8	-0.2
Age started oral contraceptive pill	0.4	0.5	2.7	1.6	-0.2	-0.8	-0.1	0.1	-0.8	0.8	-0.3	0.6
Heart disease (siblings)	0.4	0.5	0.9	0.9	-0.7	-0.8	-1.0	-0.6	-0.9	0.2	-0.7	0.8
Alcohol drinker status: Previous	0.4	0.5	2.1	1.4	0.2	-1.1	0.6	0.0	0.0	1.0	-0.4	-0.2
Mean Putamen Volume	0.3	0.3	1.1	-0.1	-0.2	0.5	-1.0	-0.1	-0.8	-0.3	-0.4	0.8
BMI	0.3	2.0	5.3	-0.5	2.3	0.9	1.7	1.0	1.1	-1.6	1.5	2.0
Hair Pigment	0.3	7.4	16.8	-0.6	3.7	1.6	4.1	2.7	2.9	-2.0	3.0	3.5
Hand grip strength (left)	0.3	0.9	1.7	1.2	-0.7	-1.2	-0.7	-0.8	-1.3	1.1	-1.2	-0.1
Hearing difficulty/problems: Yes	0.3	0.5	1.2	0.7	-0.6	-0.7	0.7	-1.1	-1.0	0.8	-0.2	0.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	0.7	0.4	-0.2	-0.5	-0.5	-0.8	0.8	0.4	-0.8	0.7
Ever had hysterectomy (womb removed)	0.3	0.3	0.7	-0.5	0.6	0.8	0.4	0.7	-0.2	-0.7	0.5	0.4
Hand grip strength (right)	0.3	0.8	1.6	1.1	-0.5	-1.3	-0.7	-1.0	-1.2	1.1	-0.9	-0.2
Serious illness, injury or assault to yourself	0.3	0.4	1.1	0.6	-0.6	-1.0	-1.0	-0.8	-0.0	0.7	-0.6	0.1
Allergy	0.3	0.8	2.0	1.4	-0.8	-1.1	-0.1	-0.9	0.2	1.1	-0.3	-1.4
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.0	-0.5	-1.1	0.3	-1.4	-0.5	-0.7	-0.1	-1.1	0.9
Loud music exposure frequency	0.3	0.3	1.2	0.4	-0.3	-0.7	0.7	-0.5	-0.5	0.7	0.1	-1.1
Medication: Paracetamol	0.3	0.6	2.8	0.5	0.4	-0.6	-0.6	-1.2	-0.7	-0.1	-0.2	1.7
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.3	1.1	-0.2	-1.0	-0.8	-0.9	-0.3	0.7	-0.9	1.1
Birth weight	0.3	0.7	2.6	-0.2	0.8	0.2	0.5	1.2	1.6	-0.5	0.9	0.8
Leg fat percentage (right)	0.3	0.9	2.9	-0.3	1.7	0.5	1.1	0.1	0.9	-1.0	1.2	1.3
Mouth/teeth dental problems: Loose teeth	0.3	0.4	0.9	0.1	-0.8	-0.3	-0.9	-0.9	-0.9	0.3	-0.7	-0.3
Medication: Seretide 50 evohaler	0.3	0.3	1.2	0.4	0.0	-0.8	-0.4	-1.1	-0.5	0.6	-0.1	0.4
Whole body fat mass	0.3	1.1	2.6	1.6	0.1	-1.6	-0.2	-1.6	-1.4	0.9	-0.6	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.6	-0.6	-0.1	0.5	-1.2	-0.1	0.4	-0.4	0.2	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.7	-0.5	-0.7	-0.2	-0.6	-1.3	-0.7	-0.1	-0.4	-0.3
Long-standing illness, disability or infirmity	0.3	0.5	3.1	-0.1	0.1	-0.1	-0.6	-0.9	-0.0	-0.2	-0.7	1.8
Medication for cholesterol	0.3	0.4	2.8	-0.1	0.2	-0.0	-0.8	-0.3	1.7	-0.1	-0.1	0.6
Breast cancer (self-reported)	0.3	0.4	1.1	-0.6	0.5	0.5	0.4	0.4	-0.5	-0.5	1.1	1.0
Medication: Gliclazide	0.3	0.3	1.1	0.2	-1.0	-0.2	-0.0	-0.8	-0.2	0.5	-0.4	-0.9
Arm fat mass (left)	0.3	1.0	2.4	1.4	-0.2	-1.4	-0.5	-1.4	-1.6	0.8	-0.6	0.8
Average weekly champagne plus white wine intake	0.3	0.4	2.7	0.3	0.7	-0.1	0.4	-0.0	0.7	-0.0	0.4	1.6
Illnesses of father: High blood pressure	0.3	0.3	0.9	-0.9	0.2	0.3	-0.3	0.4	-0.9	-0.5	0.4	-0.9
Ever smoked	0.3	0.5	1.5	0.6	-1.2	-0.8	0.2	-0.6	-0.8	0.6	-0.6	0.4
Unable to work because of sickness or disability	0.3	0.4	1.6	0.3	0.9	-0.2	-0.3	0.1	0.9	-0.3	0.0	1.3
Pain experienced in last month	0.3	0.6	2.7	0.7	-0.9	-0.5	0.3	-0.0	-0.1	1.0	-0.4	-1.6
Worry (Nagel 2018)	0.2	0.3	1.5	-0.1	0.8	0.4	-0.5	0.3	0.5	-0.5	-0.0	1.2
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.9	0.5	-0.2	-1.0	0.7	-0.2	-0.3	0.6	-0.6	-0.5
Smoking Status	0.2	0.5	2.0	0.5	-0.7	-0.6	-0.4	-0.8	-1.4	0.5	-0.6	-0.2
Sensitivity / hurt feelings	0.2	0.4	0.8	0.7	0.9	-0.3	0.6	0.6	0.1	0.1	0.9	0.8
Relative age of first facial hair	0.2	0.4	1.1	-0.5	0.1	-0.0	1.1	1.0	-0.4	-0.4	1.0	-0.4
Trunk fat percentage	0.2	0.7	1.7	1.1	0.5	-1.2	0.1	-1.3	-1.3	0.6	-0.1	0.2
Townsend deprivation index at recruitment	0.2	0.2	1.4	0.0	-0.4	0.0	0.2	-0.8	-1.2	0.1	0.2	-0.4
Current tobacco smoking	0.2	0.3	1.6	0.1	-0.7	-0.4	-0.2	-0.5	-1.3	0.6	-0.3	-0.2
Relative age voice broke	0.2	0.4	1.8	0.1	-0.2	0.2	1.3	0.3	0.3	-0.2	1.2	0.0
Supplements: Glucosamine	0.2	0.2	0.8	-0.2	0.3	0.5	0.2	0.6	0.9	-0.4	0.0	0.8
Medication: Levothyroxine sodium	0.2	0.3	0.7	0.6	-0.3	-0.6	-0.6	-0.8	-0.2	0.4	-0.5	0.8
Alcohol usually taken with meals	0.2	0.3	1.5	-0.3	0.1	0.2	0.5	0.9	0.6	-0.0	0.4	-1.2
Nervous feelings	0.2	0.3	1.9	0.6	0.6	-0.4	-1.4	0.2	-0.0	0.0	0.2	0.3
Had other major operations	0.2	0.2	1.2	-0.7	-0.3	0.5	1.1	0.3	-0.2	-0.4	0.1	0.4
Qualifications: None of the above	0.2	0.4	1.3	-1.1	0.1	0.4	-0.9	-0.4	-0.8	-0.9	0.1	0.4
Hip circumference	0.2	0.9	3.5	1.0	-0.1	-1.1	-0.4	-1.4	-1.9	0.5	-0.5	0.9
Number of live births	0.2	0.3	2.3	-0.2	0.1	0.2	-0.2	0.0	0.2	-0.7	-0.4	1.5
Noisy workplace	0.2	0.2	0.9	-0.5	-0.1	0.2	0.5	0.4	0.9	-0.3	-0.2	0.8
Mouth/teeth dental problems: Dentures	0.2	0.3	1.7	-0.3	0.2	-0.6	-1.3	-0.2	-0.2	-0.1	-0.6	1.0
Depression (self-reported)	0.2	0.3	0.8	0.7	0.5	-0.4	0.3	0.9	0.1	0.2	0.4	0.7
Breastfed as a baby	0.2	0.3	1.2	-0.5	-0.1	0.6	0.6	1.1	0.0	-0.2	0.4	-0.5
Medication for pain relief, constipation, heartburn	0.2	0.3	2.0	-0.5	-0.2	0.3	-0.0	0.5	1.4	0.0	-0.6	-0.2
Supplements: Vitamin C	0.2	0.2	0.5	0.7	-0.3	-0.7	0.6	-0.2	0.5	0.5	-0.3	-0.4
Average weekly red wine intake	0.2	0.4	1.0	-0.6	-0.5	1.0	0.7	-0.5	0.2	-0.6	0.5	-0.7
Smoking status: Current	0.2	0.3	1.6	-0.1	-0.7	-0.3	-0.1	-0.4	-1.2	0.4	-0.1	-0.3
Ever taken oral contraceptive pill	0.2	0.2	0.8	0.8	-0.0	-0.2	-0.4	0.7	0.5	0.1	0.0	0.9
Cholesterol lowering medication	0.2	0.3	1.4	0.3	-0.8	-0.3	-0.1	-0.4	-1.2	0.2	-0.6	0.2
Basal cell carcinoma (self-reported)	0.2	0.2	1.1	0.4	-0.2	-0.5	1.1	-0.6	0.4	0.4	0.1	0.3
Blood White Count	0.1	0.4	2.0	0.8	-0.1	-0.8	-0.3	-0.4	-1.4	0.6	-0.7	-0.3
Tanning	0.1	1.2	3.1	1.1	-1.3	-1.3	-0.8	-0.7	-0.1	1.5	-1.0	-1.8
Impedance of leg (right)	0.1	0.3	1.1	0.7	0.3	-0.2	-0.4	-0.5	1.0	0.5	0.0	-0.9
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.4	0.2	0.3	0.3	0.7	0.1	-0.2	0.2	0.3	-0.3
Body mass index (BMI)	0.1	0.6	3.1	-0.4	1.1	0.3	0.8	-0.0	0.1	-0.9	0.5	1.8
Impedance of leg (left)	0.1	0.4	2.4	0.1	1.1	0.4	0.1	0.5	1.6	-0.2	0.5	-0.5
Number of incorrect matches in round	0.1	0.2	0.8	0.6	-0.4	-0.2	0.3	-0.0	0.9	0.3	-0.3	-0.5
Had menopause	0.1	0.1	0.6	-0.3	-0.0	-0.0	-0.8	-0.0	-0.8	-0.1	-0.3	0.2
Pain all over the body in last month	0.1	0.1	0.5	-0.3	0.3	0.1	0.2	-0.2	0.7	-0.4	-0.1	0.6
Arm fat percentage (right)	0.1	0.6	1.6	1.1	0.2	-0.9	0.0	-1.2	-1.3	0.5	-0.1	0.4
Length of working week for main job	0.1	0.1	0.2	0.1	0.5	0.2	0.4	-0.4	0.4	-0.2	0.1	0.4
Hair/balding pattern: Pattern 4	0.1	0.4	1.4	0.8	0.2	-0.5	0.8	0.2	1.2	0.6	0.4	0.0
Body fat percentage	0.1	0.4	1.1	0.6	1.1	-0.5	0.6	-0.7	-0.5	-0.1	0.5	0.7
Leg fat mass (right)	0.1	0.4	2.1	0.7	0.8	-0.6	0.2	-0.8	-0.3	-0.0	0.2	1.5
Overall health rating	0.1	0.3	2.0	-0.3	0.3	0.3	0.4	-0.0	0.0	-0.5	-0.1	1.4
Knee pain experienced in last month	0.1	0.1	0.5	-0.3	0.4	0.0	0.7	-0.1	0.3	-0.2	0.1	0.6
Arm fat percentage (left)	0.1	0.3	0.6	0.6	0.7	-0.3	0.5	-0.5	-0.8	-0.2	0.6	0.7
Financial situation satisfaction	0.1	0.2	0.5	0.3	-0.6	-0.1	-0.0	-0.1	-0.7	0.3	-0.3	-0.7
Supplements: Calcium	0.1	0.1	0.5	-0.3	0.2	-0.4	0.5	-0.7	-0.6	-0.0	-0.0	0.1
Impedance of whole body	0.1	0.6	3.3	0.9	-0.0	-0.5	-0.6	-0.4	-0.4	0.8	-0.0	-1.8
Leg fat mass (left)	0.1	0.5	3.0	0.6	1.1	-0.5	0.3	-0.4	-0.2	-0.3	0.3	1.7
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Eosinophil Count	0.0	0.2	1.3	-1.1	0.0	0.6	-0.1	-0.3	0.2	-0.5	-0.0	-0.0
Lung FVC	0.0	0.2	0.9	0.9	-0.3	-0.1	0.4	-0.3	0.4	0.5	0.6	-0.5
Qualifications: CSEs or equivalent	0.0	0.1	0.2	0.1	0.2	0.1	-0.2	-0.3	0.3	-0.1	-0.2	0.4

Hub : Genes

GOPC

Models

Trait associations