[Hub]/) : Traits : Systolic Blood Pressure :

chr9:115,471,346-117,517,897

Best TWAS P=5.19e-10 · Best GWAS P=5e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere ZNF618 0.48 0.24 enet 10 0.17 4.4e-05 6.6 6.2 5.2e-10 0.96 0.01 0.99 TRUE
2 GTEx Esophagus Muscularis POLE3 0.16 0.16 lasso 4 0.16 7.2e-10 -5.4 5.4 7.1e-08 0.02 0.01 0.99 FALSE
3 GTEx Spleen POLE3 0.37 0.22 lasso 5 0.22 2.7e-06 -5.4 5.2 1.5e-07 0.03 0.02 0.94 FALSE
4 GTEx Whole Blood RGS3 0.26 0.14 lasso 5 0.12 1.6e-11 -5.4 5.5 5.1e-08 0.02 0.53 0.47 FALSE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma POLE3 0.10 0.04 lasso 5 0.03 7.9e-05 -5.5 5.8 6.5e-09 0.03 0.00 0.99 TRUE
6 The Cancer Genome Atlas Brain Lower Grade Glioma POLE3 0.09 0.07 lasso 2 0.05 1.8e-06 -5.4 5.4 6.9e-08 0.02 0.00 1.00 FALSE