Best TWAS P=8.52e-14 · Best GWAS P=9.84e-13 conditioned to 0.0808
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ARHGAP12 | 0.14 | 0.03 | lasso | 5 | 0.05 | 1.2e-03 | 3.2 | 5.4 | 5.3e-08 | 0.66 | 0.03 | 0.72 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | KIF5B | 0.17 | 0.10 | lasso | 6 | 0.05 | 1.0e-02 | 7.0 | 7.5 | 8.5e-14 | 0.82 | 0.03 | 0.75 | TRUE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | CCDC7 | 0.14 | 0.00 | enet | 22 | 0.02 | 8.9e-02 | 2.7 | 5.2 | 2.5e-07 | 0.45 | 0.04 | 0.44 | FALSE |
| 4 | GTEx | Muscle Skeletal | KIF5B | 0.09 | 0.04 | lasso | 6 | 0.05 | 1.2e-05 | 6.8 | 6.8 | 1.4e-11 | 0.78 | 0.03 | 0.97 | FALSE |