Best TWAS P=4.74e-08 · Best GWAS P=4.42e-10 conditioned to 0.000107
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RSL1D1 | 0.08 | 0.05 | lasso | 5 | 0.03 | 1.6e-03 | 5.5 | -5.2 | 1.5e-07 | -0.78 | 0.03 | 0.96 | FALSE |
| 2 | GTEx | Brain Cortex | RP11-166B2.1 | 0.64 | 0.46 | enet | 19 | 0.44 | 1.1e-13 | 4.9 | 5.4 | 6.4e-08 | 0.61 | 0.36 | 0.64 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Female) | RP11-166B2.1 | 0.39 | 0.40 | lasso | 2 | 0.38 | 1.9e-12 | 4.9 | 5.2 | 2.2e-07 | 0.53 | 0.18 | 0.82 | FALSE |
| 4 | GTEx | Stomach | RP11-166B2.1 | 0.46 | 0.29 | lasso | 9 | 0.27 | 1.7e-13 | 4.9 | 5.5 | 4.7e-08 | 0.55 | 0.13 | 0.87 | TRUE |
| 5 | GTEx | Testis | RP11-166B2.1 | 0.39 | 0.30 | lasso | 3 | 0.29 | 1.7e-13 | 4.9 | 5.2 | 2.3e-07 | 0.47 | 0.81 | 0.19 | FALSE |