[Hub]/) : Traits : Systolic Blood Pressure :

chr17:55,704,465-58,660,283

Best TWAS P=2.98e-11 · Best GWAS P=7.47e-10 conditioned to 0.229

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere AC099850.1 0.14 0.03 lasso 6 0.03 5.0e-02 -6.1 -6.7 3.0e-11 -0.78 0.06 0.46 TRUE
2 GTEx Heart Atrial Appendage SKA2 0.10 0.06 enet 4 0.04 5.5e-03 -6.1 -6.0 1.7e-09 -0.69 0.03 0.86 FALSE
3 GTEx Muscle Skeletal SKA2 0.04 0.02 enet 12 0.04 1.0e-04 5.7 -5.2 1.9e-07 -0.57 0.07 0.84 FALSE
4 GTEx Nerve Tibial RPS6KB1 0.05 0.01 lasso 4 0.00 1.6e-01 4.7 -5.5 2.9e-08 -0.04 0.04 0.47 TRUE
5 GTEx Nerve Tibial SKA2 0.10 0.08 lasso 6 0.09 4.4e-07 5.4 -5.2 2.5e-07 -0.65 0.06 0.94 FALSE
6 GTEx Pituitary BZRAP1-AS1 0.16 0.04 enet 8 0.02 8.0e-02 4.9 5.2 1.5e-07 0.47 0.08 0.20 FALSE
7 METSIM Adipose TEX14 0.05 0.05 lasso 2 0.04 4.1e-07 5.7 5.7 1.3e-08 0.63 0.05 0.95 FALSE