[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr17:58,828,402-63,353,913

Best TWAS P=1.15e-24 · Best GWAS P=6.52e-22 conditioned to 0.0193

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ACE	0.08	0.05	lasso	4	0.04	1.0e-05	5.092	6.1	9.8e-10	-0.06	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MARCH10	0.08	0.00	bslmm	252	0.02	2.3e-03	3.206	-5.8	5.8e-09	0.02	0.03	0.60	TRUE
3	GTEx	Adipose Visceral Omentum	TBX2	0.19	0.04	lasso	4	0.10	1.0e-05	-9.071	-6.5	7.4e-11	-0.12	0.01	0.93	FALSE
4	GTEx	Adipose Visceral Omentum	RP11-332H18.4	0.22	0.07	lasso	7	0.05	9.0e-04	-9.071	-8.6	1.0e-17	-0.10	0.01	0.98	FALSE
5	GTEx	Artery Tibial	DDX5	0.12	0.13	lasso	2	0.12	1.5e-09	-7.226	7.2	6.1e-13	-0.12	1.00	0.00	TRUE
6	GTEx	Artery Tibial	TEX2	0.07	0.03	lasso	4	0.03	1.7e-03	-8.804	-10.3	1.2e-24	0.78	0.25	0.66	TRUE
7	GTEx	Artery Tibial	RP11-332H18.4	0.18	0.15	lasso	1	0.14	4.5e-11	-9.071	-9.1	1.2e-19	-0.09	0.00	1.00	FALSE
8	GTEx	Cells Transformed fibroblasts	MRC2	0.10	0.02	enet	17	0.02	1.5e-02	4.263	-5.1	2.8e-07	0.04	0.08	0.55	FALSE
9	GTEx	Cells Transformed fibroblasts	RP11-332H18.4	0.19	0.16	lasso	4	0.14	1.7e-10	-9.071	-9.0	1.6e-19	-0.09	0.00	1.00	FALSE
10	GTEx	Colon Sigmoid	CD79B	0.17	0.00	lasso	9	0.08	9.7e-04	0.093	5.8	6.5e-09	-0.47	0.04	0.56	FALSE
11	GTEx	Colon Transverse	ACE	0.31	0.28	lasso	2	0.28	1.8e-13	7.543	-7.0	3.0e-12	0.01	0.00	1.00	FALSE
12	GTEx	Esophagus Mucosa	TEX2	0.17	0.08	enet	12	0.11	6.2e-08	-5.491	-7.7	9.7e-15	0.52	0.70	0.23	FALSE
13	GTEx	Esophagus Mucosa	MIR5047	0.06	0.01	lasso	5	0.00	3.4e-01	-7.428	8.2	2.2e-16	-0.55	0.10	0.24	FALSE
14	GTEx	Esophagus Mucosa	RP11-332H18.4	0.19	0.09	lasso	4	0.04	9.6e-04	-9.071	-9.2	4.1e-20	-0.09	0.00	0.99	TRUE
15	GTEx	Lung	TEX2	0.04	0.02	enet	13	0.01	5.0e-02	-8.549	-6.6	3.8e-11	0.41	0.09	0.44	FALSE
16	GTEx	Lung	RP11-332H18.4	0.10	0.04	enet	3	0.07	6.8e-06	-9.071	-8.1	8.1e-16	-0.08	0.01	0.99	FALSE
17	GTEx	Testis	TBX2	0.20	0.18	lasso	3	0.15	4.8e-07	-9.071	-9.1	7.3e-20	-0.09	0.00	1.00	FALSE
18	GTEx	Testis	RP11-332H18.4	0.19	0.19	lasso	2	0.16	1.6e-07	-9.003	-9.2	4.4e-20	-0.08	0.01	0.99	FALSE
19	GTEx	Thyroid	TBX2	0.10	0.09	lasso	2	0.06	1.7e-05	-9.071	-9.1	1.2e-19	-0.09	0.00	0.99	FALSE
20	GTEx	Vagina	SMURF2	0.32	0.00	enet	1	0.06	1.4e-02	-5.455	-5.5	4.9e-08	0.03	0.03	0.16	FALSE
21	NTR	Blood	DDX5	0.10	0.04	lasso	3	0.04	5.2e-13	-7.226	7.1	1.4e-12	-0.12	1.00	0.00	FALSE
22	YFS	Blood	DDX5	0.42	0.21	bslmm	215	0.21	7.7e-68	-7.226	6.8	7.2e-12	-0.08	1.00	0.00	FALSE
23	YFS	Blood	ERN1	0.01	0.00	bslmm	309	0.00	5.9e-02	-8.804	6.2	4.3e-10	-0.36	0.02	0.05	FALSE
24	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C17orf82	0.03	0.02	blup	42	0.00	1.3e-01	-6.350	8.0	1.4e-15	0.06	0.06	0.58	FALSE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	ACE	0.02	0.01	enet	3	0.01	1.3e-03	4.712	6.0	1.8e-09	0.01	0.00	0.98	FALSE
26	The Cancer Genome Atlas	Colon Adenocarcinoma	ACE	0.34	0.22	lasso	5	0.22	6.5e-13	4.712	-6.2	4.8e-10	-0.01	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ACE	0.16	0.08	lasso	2	0.07	5.8e-05	4.712	-6.4	1.7e-10	-0.01	0.00	1.00	FALSE
28	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TEX2	0.02	0.00	blup	42	0.01	4.4e-02	-7.428	-8.5	2.2e-17	0.60	0.02	0.74	FALSE
29	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TEX2	0.06	0.01	blup	42	0.01	3.9e-02	-6.063	-8.1	4.1e-16	0.50	0.01	0.82	FALSE
30	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ACE	0.13	0.14	lasso	1	0.10	6.6e-05	7.543	-7.5	4.6e-14	0.00	0.00	1.00	TRUE
31	The Cancer Genome Atlas	Rectum Adenocarcinoma	ACE	0.16	0.14	lasso	6	0.13	5.1e-04	7.543	-7.5	6.9e-14	0.03	0.00	0.88	FALSE