Best TWAS P=9.07e-10 · Best GWAS P=1.98e-07 conditioned to 0.446
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNF585B | 0.09 | 0.06 | enet | 20 | 0.09 | 2.6e-11 | -4.6 | -5.3 | 1.4e-07 | -0.64 | 0.14 | 0.82 | FALSE |
| 2 | GTEx | Brain Hippocampus | ZNF568 | 0.19 | -0.01 | enet | 10 | 0.03 | 7.9e-02 | -3.8 | -5.1 | 2.9e-07 | -0.36 | 0.07 | 0.30 | FALSE |
| 3 | GTEx | Muscle Skeletal | ZNF781 | 0.06 | 0.02 | enet | 15 | 0.03 | 8.4e-04 | 5.1 | 5.5 | 4.6e-08 | 0.77 | 0.01 | 0.94 | FALSE |
| 4 | YFS | Blood | ZNF571 | 0.00 | 0.00 | bslmm | 295 | 0.00 | 6.3e-02 | -3.0 | 5.8 | 9.1e-09 | 0.52 | 0.05 | 0.24 | FALSE |
| 5 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ZNF607 | 0.09 | 0.00 | blup | 40 | 0.01 | 2.0e-02 | 3.5 | 5.1 | 2.8e-07 | 0.52 | 0.00 | 0.00 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZNF585B | 0.03 | 0.02 | enet | 4 | 0.02 | 5.4e-06 | -4.5 | -5.2 | 2.0e-07 | -0.76 | 0.01 | 0.85 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF585B | 0.05 | 0.00 | blup | 32 | 0.03 | 1.1e-04 | -4.5 | -6.1 | 9.1e-10 | -0.77 | 0.00 | 0.74 | TRUE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SIPA1L3 | 0.12 | 0.08 | blup | 123 | 0.09 | 1.6e-09 | -2.9 | -5.6 | 1.9e-08 | -0.35 | 0.11 | 0.72 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZNF585B | 0.12 | 0.04 | enet | 9 | 0.07 | 5.6e-08 | -4.5 | -5.2 | 1.9e-07 | -0.79 | 0.02 | 0.94 | FALSE |