[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr19:45,585,167-46,994,833

Best TWAS P=1.95e-14 · Best GWAS P=2.17e-13 conditioned to 0.183

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum DMWD 0.11 0.13 lasso 2 0.16 7.3e-09 4.0 6.0 1.6e-09 -0.85 0.03 0.97 FALSE
2 GTEx Artery Aorta DMWD 0.28 0.19 lasso 3 0.15 1.2e-08 -7.1 6.9 4.0e-12 -0.94 0.01 0.99 FALSE
3 GTEx Artery Tibial DMPK 0.12 0.03 lasso 4 0.03 3.1e-03 4.3 6.8 1.3e-11 -0.70 0.03 0.94 FALSE
4 GTEx Artery Tibial DMWD 0.22 0.17 lasso 8 0.16 6.8e-13 -7.1 7.3 2.7e-13 -0.97 0.01 0.99 FALSE
5 GTEx Artery Tibial AC074212.6 0.14 0.04 lasso 5 0.06 2.4e-05 -7.3 7.7 1.9e-14 -0.87 0.01 0.99 TRUE
6 GTEx Cells Transformed fibroblasts DMPK 0.10 0.07 lasso 6 0.07 1.0e-05 5.3 5.5 4.2e-08 -0.43 0.89 0.02 FALSE
7 GTEx Cells Transformed fibroblasts AC074212.6 0.07 0.05 enet 7 0.05 1.5e-04 5.4 5.3 1.2e-07 -0.44 0.53 0.03 FALSE
8 GTEx Lung DMPK 0.10 0.05 lasso 3 0.05 5.4e-05 4.0 5.3 9.8e-08 -0.77 0.03 0.96 FALSE
9 GTEx Muscle Skeletal DMWD 0.06 0.01 lasso 6 0.01 1.9e-02 -7.1 6.9 5.8e-12 -0.91 0.01 0.97 FALSE
10 GTEx Nerve Tibial DMWD 0.24 0.07 lasso 6 0.06 5.8e-05 -7.1 6.0 1.5e-09 -0.86 0.02 0.98 FALSE
11 GTEx Thyroid DMPK 0.13 0.11 lasso 2 0.12 1.3e-09 4.0 5.4 7.0e-08 -0.78 0.16 0.84 FALSE
12 GTEx Thyroid DMWD 0.11 0.12 lasso 3 0.11 6.7e-09 4.1 5.8 5.1e-09 -0.83 0.02 0.98 FALSE
13 GTEx Thyroid AC074212.6 0.08 0.10 lasso 2 0.09 1.8e-07 -7.1 7.0 1.9e-12 -0.95 0.01 0.99 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma DMWD 0.01 0.00 blup 42 0.01 7.3e-03 3.9 -7.1 1.3e-12 0.83 0.01 0.79 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SIX5 0.05 0.05 lasso 8 0.03 7.6e-03 -7.1 -6.9 4.4e-12 0.98 0.01 0.94 FALSE