TWAS hub - ZNF585B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0850	0.0340	1.4e-07	0.065	0.077	0.092	0.082	0.074	2.3e-08	1.2e-09	2.6e-11	3.8e-10	2.5e-09
2	GTEx	Adipose Subcutaneous	0.1030	0.0380	4.4e-09	0.099	NA	0.113	NA	0.115	1.7e-08	NA	1.8e-09	NA	1.2e-09
3	GTEx	Adipose Visceral Omentum	0.0640	0.0350	8.7e-03	0.022	NA	0.002	NA	0.001	2.5e-02	NA	2.5e-01	NA	2.7e-01
4	GTEx	Artery Aorta	0.0930	0.0500	3.5e-03	0.035	NA	0.052	NA	0.030	4.9e-03	NA	7.4e-04	NA	8.8e-03
5	GTEx	Artery Tibial	0.1741	0.0451	0.0e+00	0.140	NA	0.211	NA	0.218	4.6e-11	NA	1.9e-16	NA	5.6e-17
6	GTEx	Brain Cerebellum	0.1190	0.0690	6.4e-03	0.002	NA	-0.010	NA	0.001	2.7e-01	NA	9.4e-01	NA	2.9e-01
7	GTEx	Cells EBV-transformed lymphocytes	0.1340	0.0650	8.4e-04	0.096	NA	0.133	NA	0.085	5.0e-04	NA	4.3e-05	NA	1.0e-03
8	GTEx	Cells Transformed fibroblasts	0.1740	0.0520	2.7e-14	0.195	NA	0.223	NA	0.205	1.3e-14	NA	1.2e-16	NA	2.7e-15
9	GTEx	Esophagus Mucosa	0.0960	0.0470	7.3e-05	0.037	NA	0.050	NA	0.052	1.6e-03	NA	2.9e-04	NA	2.2e-04
10	GTEx	Esophagus Muscularis	0.1430	0.0510	3.6e-07	0.064	NA	0.117	NA	0.077	1.0e-04	NA	1.4e-07	NA	2.0e-05
11	GTEx	Lung	0.0631	0.0299	1.1e-04	0.081	NA	0.046	NA	0.068	9.2e-07	NA	1.9e-04	NA	7.0e-06
12	GTEx	Skin Sun Exposed Lower leg	0.1120	0.0550	5.9e-05	0.046	NA	0.041	NA	0.043	1.1e-04	NA	2.3e-04	NA	1.8e-04
13	GTEx	Stomach	0.0730	0.0410	4.8e-03	0.070	NA	0.049	NA	0.054	3.1e-04	NA	2.3e-03	NA	1.4e-03
14	GTEx	Thyroid	0.0360	0.0200	6.5e-03	0.034	NA	0.008	NA	0.012	1.3e-03	NA	7.6e-02	NA	4.0e-02
15	YFS	Blood	0.0404	0.0184	2.1e-04	0.003	0.012	0.015	0.013	0.009	2.2e-02	7.0e-05	9.7e-06	3.4e-05	4.8e-04
16	TCGA	Breast Invasive Carcinoma	0.0287	0.0164	4.2e-04	0.016	0.009	0.025	NA	0.011	2.8e-04	4.6e-03	5.4e-06	NA	2.4e-03
17	TCGA	Kidney Renal Clear Cell Carcinoma	0.1103	0.0665	5.7e-05	0.036	0.063	0.050	NA	0.044	5.6e-05	1.3e-07	2.3e-06	NA	1.0e-05
18	TCGA	Brain Lower Grade Glioma	0.1281	0.0579	1.5e-07	0.031	0.066	0.082	NA	0.070	1.5e-04	5.7e-08	1.5e-09	NA	2.3e-08
19	TCGA	Lung Adenocarcinoma	0.0479	0.0251	3.5e-04	0.005	0.032	0.024	NA	0.019	8.3e-02	1.1e-04	7.4e-04	NA	2.1e-03
20	TCGA	Lung Squamous Cell Carcinoma	0.0228	0.0137	4.5e-03	0.014	0.020	0.013	NA	0.014	9.3e-03	2.4e-03	1.2e-02	NA	7.9e-03
21	TCGA	Prostate Adenocarcinoma	0.1165	0.0587	3.4e-06	0.035	0.040	0.072	NA	0.035	1.3e-04	4.9e-05	5.5e-08	NA	1.4e-04
22	TCGA	Thyroid Carcinoma	0.0710	0.0340	2.2e-07	0.060	0.068	0.068	NA	0.067	1.7e-06	3.8e-07	3.4e-07	NA	3.9e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Shortness of breath walking on level ground	7.3	8.6	23.6	2.4	3.1	3.1	2.8	3.0	1.6	1.9	2.7	2.6	2.7	3.1	1.9	3.4	3.5	2.0	4.0	3.6	3.6	3.1	-0.0	4.9	2.0
Multivitamins +/- minerals	6.3	8.1	16.2	1.9	3.2	3.3	2.8	3.6	0.5	1.7	3.3	2.3	2.9	3.6	1.5	3.2	4.0	3.5	3.5	1.3	3.0	2.8	-1.2	3.2	2.8
Irritability	6.0	10.1	18.0	-3.5	-3.4	-4.0	-3.4	-3.2	-1.2	-3.7	-4.2	-3.8	-3.2	-3.1	-3.1	-4.2	-3.1	1.1	-3.0	-2.4	-2.5	-3.0	0.6	-2.7	-4.0
Crohns Disease (2017)	5.9	13.0	20.9	-3.4	-3.7	-4.5	-4.6	-4.1	-1.8	-3.8	-4.4	-3.7	-4.3	-3.9	-2.8	-4.2	-4.2	-1.7	-3.5	-2.7	-3.6	-3.2	1.2	-3.6	-3.9
Crohns Disease (2012)	5.8	9.3	18.5	-3.6	-2.7	-3.2	-4.3	-3.5	-1.7	-2.5	-3.7	-3.0	-3.8	-2.6	-2.3	-3.2	-3.1	-2.1	-3.4	-1.6	-2.9	-3.7	0.8	-3.4	-3.5
Blood clot in the leg (DVT)	5.8	7.5	13.7	2.6	2.6	3.4	2.0	3.7	-0.5	1.6	3.3	1.8	2.7	3.1	0.7	3.3	3.5	1.5	2.9	3.1	3.4	2.1	-2.0	3.5	3.4
Deep venous thrombosis (DVT) (self-reported)	5.8	7.5	13.4	2.6	2.7	3.4	2.1	3.7	-0.2	1.6	3.3	1.8	2.6	3.1	0.8	3.2	3.5	1.8	2.9	3.1	3.5	2.1	-2.0	3.5	3.3
Medication: Lisinopril	5.7	7.4	11.2	-3.3	-2.8	-3.1	-3.0	-2.9	-1.8	-3.0	-3.3	-3.0	-3.0	-2.8	-2.4	-3.0	-2.6	-1.5	-2.8	-2.4	-2.8	-2.9	0.3	-2.6	-2.9
Comparative height size at age 10	5.6	31.1	54.3	-5.4	-6.5	-6.9	-4.3	-6.2	-1.9	-5.8	-6.8	-6.0	-5.7	-6.5	-4.4	-7.4	-6.2	1.6	-5.6	-6.3	-5.5	-4.5	1.4	-5.9	-6.1
Average weekly red wine intake	5.5	8.2	14.8	-2.8	-2.9	-3.2	-2.1	-3.1	-1.0	-2.5	-3.1	-2.7	-2.6	-2.9	-1.9	-3.4	-3.4	-2.6	-3.7	-3.4	-3.3	-2.9	0.4	-3.9	-2.7
Hand grip strength (left)	5.1	13.5	25.8	-2.1	-3.4	-4.0	-3.0	-4.9	-0.3	-2.1	-4.5	-2.6	-4.9	-4.0	-1.4	-4.0	-4.8	-3.3	-5.1	-3.3	-5.1	-3.0	2.4	-4.9	-3.2
Happiness	5.1	6.2	11.3	-2.8	-2.3	-2.8	-1.2	-2.3	-0.7	-3.2	-2.9	-3.0	-2.1	-2.1	-2.5	-3.2	-2.4	-0.1	-3.4	-2.6	-2.9	-3.0	-0.2	-2.9	-2.2
Exposure to tobacco smoke outside home	5.0	6.6	13.9	3.2	2.3	2.9	2.1	2.2	1.5	2.5	2.5	2.8	2.3	2.1	2.4	2.8	2.5	-0.2	3.5	3.2	3.7	2.9	-0.0	3.2	2.2
Hand grip strength (right)	4.7	12.7	26.7	-1.6	-3.4	-3.5	-2.2	-4.8	0.1	-2.4	-4.2	-2.3	-4.7	-4.1	-1.0	-3.8	-4.5	-4.4	-5.2	-2.9	-5.1	-3.0	2.2	-4.7	-2.8
Falls in the last year	4.7	6.4	11.4	1.6	2.8	2.9	3.4	2.7	1.0	1.6	2.7	2.4	2.3	3.1	1.8	3.0	3.2	3.1	3.2	1.3	2.7	2.6	-0.5	2.9	2.4
Pulse wave reflection index	4.5	5.5	11.7	1.9	2.4	2.4	1.2	3.3	-1.3	1.5	2.5	0.7	2.8	3.1	-0.3	2.9	3.4	1.4	2.5	2.5	3.4	1.9	-1.6	3.0	2.4
Height	4.4	85.7	148.8	-9.3	-10.3	-11.3	-6.3	-11.1	-0.9	-10.2	-11.0	-9.2	-9.8	-10.6	-6.3	-12.2	-11.0	-1.7	-10.2	-9.4	-9.0	-8.6	2.7	-10.6	-10.3
Chronic bronchitis/emphysema (mother)	4.2	4.8	13.2	1.5	2.6	1.6	1.3	1.4	1.9	2.5	1.4	2.5	1.0	2.5	2.4	2.0	2.4	3.6	3.6	1.2	2.3	3.0	1.5	2.5	0.3
Mood swings	4.0	7.2	16.2	-4.0	-2.8	-3.0	-2.3	-2.1	-2.0	-3.8	-3.3	-3.6	-2.4	-2.1	-3.3	-3.2	-2.7	0.1	-2.7	-1.0	-2.1	-3.5	-0.7	-1.4	-2.7
Vitamin and mineral supplements	3.9	5.3	12.9	-0.9	-2.1	-2.2	-1.5	-3.2	0.4	-1.0	-2.4	-1.0	-2.3	-2.7	-0.2	-2.5	-3.1	-3.5	-3.2	-1.2	-2.9	-2.3	1.5	-3.6	-2.1
Primary Biliary Cirrhosis	3.8	5.5	15.3	-2.2	-1.7	-2.8	-3.1	-3.2	1.5	-0.6	-2.8	-1.2	-3.2	-2.1	-0.5	-2.4	-2.4	-2.5	-1.8	-1.0	-2.1	-1.7	2.8	-2.3	-3.9
Systolic Blood Pressure	3.8	19.3	37.5	-5.3	-4.9	-4.1	-4.3	-3.9	-4.7	-5.0	-4.1	-4.7	-4.3	-4.5	-4.3	-4.4	-4.5	-2.8	-5.2	-3.1	-4.0	-6.1	-1.9	-5.2	-3.1
Supplements: Fish oil (including cod liver oil)	3.8	5.0	8.9	2.2	2.6	2.5	1.4	2.1	0.8	2.8	2.2	2.4	2.0	2.5	1.7	2.8	2.6	-0.1	2.8	2.5	2.4	2.2	-0.2	3.0	2.1
Irritable Bowel Disease (IBD)	3.7	8.7	14.3	-2.7	-3.5	-3.7	-3.2	-3.1	-1.8	-3.8	-3.5	-3.4	-2.6	-3.5	-3.0	-3.6	-3.4	-0.9	-2.9	-2.2	-2.7	-2.7	0.3	-2.5	-3.0
Illnesses of father: High blood pressure	3.7	4.6	9.2	-1.4	-2.8	-2.3	-1.6	-1.8	-2.1	-2.6	-2.1	-2.2	-1.3	-3.0	-1.8	-2.7	-3.0	0.3	-2.3	-2.4	-2.0	-2.3	-1.0	-2.6	-1.2
Sitting height	3.6	25.7	44.5	-4.5	-6.0	-6.3	-3.8	-5.4	-2.0	-5.8	-5.8	-5.1	-4.7	-6.3	-3.4	-6.7	-6.6	0.4	-5.3	-5.7	-4.9	-4.4	0.6	-6.0	-5.1
High blood pressure (mother)	3.5	4.9	10.9	-2.1	-2.9	-1.9	-1.3	-1.0	-2.5	-3.0	-1.6	-2.9	-0.3	-2.5	-2.6	-2.5	-2.5	0.3	-2.5	-1.9	-1.1	-3.3	-2.5	-2.7	-0.7
Back pain experienced in last month	3.4	5.0	13.9	1.5	2.2	2.0	2.1	1.8	1.4	2.4	2.1	2.5	1.7	2.1	2.1	2.4	2.1	0.9	3.7	1.8	2.9	3.0	0.7	3.5	1.1
Alcohol usually taken with meals	3.3	5.4	8.9	-1.9	-2.7	-2.9	-2.0	-2.3	-1.4	-1.7	-2.7	-2.9	-1.7	-2.5	-2.4	-3.0	-2.6	-2.0	-2.9	-1.7	-2.6	-2.4	0.2	-2.5	-2.1
Standing height	3.3	32.4	56.1	-5.8	-6.7	-7.0	-3.9	-6.3	-1.9	-6.6	-6.8	-6.4	-5.5	-6.6	-4.8	-7.5	-6.5	-0.2	-6.1	-5.8	-5.4	-5.2	0.9	-6.0	-6.1
Tense / ‘highly strung’	3.3	5.4	10.8	-2.8	-2.7	-3.0	-1.3	-2.2	-0.5	-2.9	-2.8	-3.0	-2.1	-2.3	-2.5	-3.3	-2.3	1.2	-2.2	-1.9	-2.0	-2.1	0.5	-1.8	-2.9
Smoking status: Previous	3.3	4.9	14.4	-2.6	-2.5	-2.9	-3.8	-2.3	-1.0	-1.2	-2.3	-2.3	-2.9	-2.7	-1.9	-2.7	-2.9	-0.2	-1.6	-1.9	-1.7	-1.4	0.4	-1.6	-2.2
Bipolar Disorder (2011)	2.9	2.8	5.9	1.5	2.2	2.1	1.5	0.8	1.7	1.9	1.3	2.4	0.7	2.2	2.4	2.0	2.3	-1.0	1.5	1.4	1.2	1.6	1.1	1.2	1.0
Had menopause	2.9	3.6	8.2	-2.0	-2.4	-1.9	-1.3	-1.2	-1.8	-2.9	-1.5	-2.7	-0.8	-2.0	-2.5	-2.4	-2.2	-0.7	-2.2	-1.0	-1.1	-2.5	-1.6	-1.8	-0.9
Neuroticism score	2.8	5.9	17.0	-3.5	-2.7	-2.5	-0.4	-1.6	-1.3	-4.1	-2.5	-3.4	-1.6	-2.1	-3.1	-3.2	-2.1	1.9	-2.6	-2.0	-1.7	-2.8	-1.0	-1.6	-2.1
Hypertension (Self-reported)	2.8	7.7	21.7	-3.5	-3.6	-2.6	-3.4	-1.4	-4.7	-3.0	-2.6	-3.8	-1.1	-3.0	-4.1	-2.7	-2.7	0.2	-2.2	-0.7	-1.3	-3.7	-2.3	-1.8	-1.4
Relative age voice broke	2.7	4.1	7.3	2.4	2.7	2.2	1.4	1.6	2.2	2.4	2.0	2.3	1.0	2.5	2.0	2.4	2.4	0.4	2.1	1.8	1.8	2.5	0.6	2.0	1.7
Mineral and other dietary supplements	2.7	3.7	8.4	-2.0	-2.0	-2.0	-1.5	-1.9	-0.7	-2.1	-1.9	-1.9	-1.8	-1.8	-1.4	-2.2	-2.1	-0.5	-2.6	-2.1	-2.2	-2.3	0.2	-2.9	-1.9
Vascular/heart problems diagnosed by doctor	2.7	7.3	24.6	3.6	3.4	2.5	2.9	1.2	5.0	2.9	2.3	3.7	1.2	2.8	4.0	2.5	2.6	-0.9	2.0	1.2	1.5	3.5	2.5	1.5	1.2
Blood Eosinophil Count	2.6	19.7	38.9	-2.8	-5.0	-5.4	-3.5	-5.9	0.9	-3.3	-4.9	-3.1	-4.6	-5.9	-1.4	-5.9	-5.6	-2.2	-4.8	-4.7	-4.5	-3.5	2.6	-6.2	-5.1
Qualifications: CSEs or equivalent	2.6	3.5	6.7	1.5	2.0	2.5	1.7	1.9	0.2	1.9	2.2	1.9	1.8	1.9	1.4	2.6	2.3	-1.4	1.8	2.3	1.5	1.3	-0.5	2.5	1.9
Arm fat percentage (right)	2.6	10.3	22.2	3.2	3.6	3.5	2.1	3.4	1.2	2.4	3.7	2.9	2.7	3.8	2.3	3.5	3.6	3.0	4.4	3.1	4.7	3.3	-0.9	3.8	2.8
Comparative body size at age 10	2.6	7.1	17.1	2.9	2.0	3.0	2.0	3.3	-1.2	0.9	3.1	1.9	2.6	2.4	1.2	2.8	2.9	4.1	3.5	2.0	3.7	2.5	-2.3	2.6	3.1
Ever had stillbirth, spontaneous miscarriage or termination	2.6	2.8	5.0	1.6	2.2	1.7	2.1	1.4	1.6	1.3	2.0	2.1	0.9	2.2	2.2	1.7	1.6	2.1	1.9	0.1	1.6	2.0	0.3	0.7	1.2
Lupus	2.5	3.8	16.1	-2.2	-2.3	-1.3	-0.5	-0.1	-3.0	-4.0	-1.0	-2.9	-0.5	-1.6	-3.0	-1.7	-1.4	0.2	-1.6	-1.3	-0.5	-2.5	-2.7	-1.2	-0.4
Chest pain or discomfort	2.5	3.7	8.5	1.0	1.6	2.5	2.3	2.6	0.1	0.5	2.9	1.3	2.6	2.0	0.7	2.3	2.2	2.9	1.4	1.0	1.7	0.9	-1.7	1.5	2.5
Forced expiratory volume in 1-second (FEV1), predicted	2.5	5.3	8.0	-2.5	-2.4	-2.6	-1.7	-2.2	-1.0	-2.8	-2.6	-2.6	-2.2	-2.5	-2.0	-2.7	-2.3	-0.1	-2.7	-2.8	-2.7	-2.3	-0.1	-2.4	-2.4
Arm fat percentage (left)	2.5	10.1	24.7	3.0	3.5	3.4	1.7	3.4	0.9	2.2	3.6	2.7	2.5	3.8	2.1	3.5	3.6	3.0	4.5	3.3	5.0	3.1	-1.0	3.8	2.7
High blood pressure	2.3	6.4	20.3	-3.2	-3.2	-2.3	-3.1	-1.0	-4.5	-2.8	-2.2	-3.6	-0.9	-2.6	-3.9	-2.4	-2.4	0.4	-1.8	-0.5	-0.9	-3.3	-2.4	-1.3	-1.1
Waist circumference	2.3	8.4	23.6	2.8	2.9	3.0	1.7	2.8	1.1	1.9	3.0	2.3	1.8	3.0	1.9	2.9	3.1	3.1	4.4	3.6	4.9	3.1	-0.7	4.0	2.2
Leg fat percentage (right)	2.3	8.3	16.3	2.9	3.2	3.4	2.1	2.9	0.9	2.0	3.0	2.8	1.8	3.2	2.1	3.4	3.2	2.5	3.8	3.4	4.0	2.8	-0.7	3.7	2.8
Number of full sisters	2.3	2.8	8.1	1.6	1.1	2.0	0.9	2.1	-0.2	0.8	2.0	1.4	1.1	1.2	0.6	2.0	1.4	2.9	1.9	1.7	1.9	1.6	-1.2	2.1	2.6
Body fat percentage	2.2	8.6	22.9	2.7	3.2	3.0	1.1	3.0	1.0	2.0	3.0	2.4	2.0	3.4	1.8	3.1	3.4	3.0	4.5	3.5	4.8	3.1	-0.5	3.9	2.0
Ever had bowel cancer screening	2.2	2.5	5.8	1.4	1.9	1.2	1.6	1.3	1.2	1.9	1.6	2.0	1.6	1.8	1.9	1.6	1.7	2.4	2.0	0.3	1.0	2.1	1.1	1.1	0.5
Wears glasses or contact lenses	2.2	2.5	4.5	-1.5	-2.0	-2.0	-0.8	-1.6	-1.4	-1.1	-2.1	-1.6	-0.4	-1.9	-1.2	-2.0	-1.7	-0.6	-1.5	-2.1	-1.9	-1.4	0.2	-1.9	-1.8
Fractured/broken bones in last 5 years	2.2	2.9	9.1	1.0	0.3	2.0	2.7	2.5	-1.4	-0.3	2.0	0.2	2.9	0.7	-0.6	1.3	0.8	0.8	0.8	1.7	1.7	-0.1	-3.0	1.5	2.8
Neuroticism	2.1	5.0	15.3	-3.2	-2.4	-2.3	-0.1	-1.3	-1.7	-3.9	-2.3	-3.3	-1.2	-1.9	-3.1	-3.0	-2.0	1.7	-2.3	-1.4	-1.2	-2.8	-1.4	-1.2	-1.6
Current tobacco smoking	2.0	3.3	8.1	1.1	2.1	2.1	2.8	1.4	1.5	1.6	1.7	2.0	0.7	2.0	1.8	1.9	2.3	2.3	2.2	0.6	1.7	2.2	0.5	2.0	1.2
Average weekly beer plus cider intake	2.0	2.9	5.7	1.5	2.4	2.0	0.4	1.5	0.9	2.0	2.0	2.3	1.2	2.2	2.0	2.4	2.0	-0.7	2.0	1.0	1.7	1.9	0.3	1.6	1.4
Risk taking	2.0	3.0	7.8	0.8	2.3	0.9	2.3	0.7	2.4	1.2	0.9	1.8	0.8	2.1	2.2	1.1	1.8	2.2	2.3	-0.2	1.2	2.8	2.1	1.9	-0.4
Illnesses of mother	1.9	2.4	5.6	1.8	1.9	1.8	1.3	1.6	1.2	1.4	1.5	1.5	1.0	1.9	1.2	1.9	1.9	0.4	1.3	1.6	1.1	1.9	0.3	2.4	1.5
Angina (self-reported)	1.9	2.5	6.1	0.6	1.4	2.1	1.7	2.1	-1.0	0.7	2.3	1.3	1.5	1.5	0.7	1.9	1.6	2.4	1.3	0.7	1.0	0.8	-1.8	1.4	2.5
Leg fat percentage (left)	1.9	6.9	15.6	2.3	2.7	3.0	1.5	2.7	0.6	1.5	2.6	2.2	1.5	2.9	1.5	3.0	3.0	2.9	3.7	3.3	4.0	2.5	-0.8	3.6	2.4
Neuroticism (Nagel 2018)	1.8	4.2	10.7	-3.1	-2.1	-2.2	-1.2	-1.4	-0.8	-3.3	-2.3	-2.7	-1.5	-1.6	-2.4	-2.8	-1.7	1.9	-2.0	-1.5	-1.0	-2.6	-0.8	-1.5	-2.1
Reaction Time	1.8	3.4	7.9	0.7	1.3	2.3	0.7	2.8	-1.0	-0.6	2.1	0.1	2.0	2.3	-0.8	2.2	2.7	1.2	1.2	2.4	2.6	-0.1	-2.8	1.7	2.3
Trunk fat percentage	1.8	7.2	20.2	2.4	2.9	2.5	0.9	2.6	1.1	1.9	2.7	2.1	1.8	3.1	1.7	2.6	3.0	3.2	4.3	3.0	4.5	3.0	-0.2	3.5	1.4
Body mass index (BMI)	1.8	7.7	15.3	3.3	3.1	3.4	2.4	2.9	1.0	1.5	3.2	2.7	2.0	3.2	2.2	3.0	2.9	1.9	3.3	3.0	3.9	2.5	-1.2	3.0	3.1
Number of incorrect matches in round	1.8	3.1	7.6	-1.4	-2.1	-2.4	-2.8	-2.0	-0.6	-0.6	-2.4	-1.8	-2.0	-2.3	-1.4	-2.2	-2.0	0.1	-1.5	-1.0	-1.5	-1.2	0.7	-1.4	-2.1
Peak expiratory flow (PEF)	1.8	4.2	9.4	-1.1	-2.6	-2.2	-3.1	-2.2	-2.2	-1.2	-3.0	-2.0	-1.7	-2.6	-1.8	-2.0	-2.3	-2.4	-2.3	-0.2	-2.2	-1.9	0.3	-1.4	-1.5
Smoking status: Current	1.8	2.8	7.7	1.1	2.0	1.9	2.8	1.2	1.5	1.6	1.6	1.8	0.5	1.9	1.6	1.7	2.1	2.1	2.0	0.6	1.5	2.0	0.5	2.0	1.1
Worry (Nagel 2018)	1.7	3.7	7.5	-2.6	-2.4	-2.3	-0.8	-1.5	-1.3	-2.7	-2.4	-2.7	-0.9	-1.9	-2.5	-2.6	-1.8	1.2	-1.6	-1.8	-1.1	-1.9	-0.6	-1.3	-2.0
Type 2 Diabetes (T2D) (2012)	1.7	1.9	4.0	-1.2	-1.6	-1.5	-0.1	-1.7	0.6	-1.4	-1.4	-0.9	-1.0	-1.8	-0.4	-1.7	-2.0	0.4	-1.7	-1.8	-1.7	-1.3	0.6	-1.9	-1.5
Hearing difficulty/problems: Yes	1.7	2.6	5.5	0.8	1.9	1.9	1.0	2.3	-1.2	1.3	1.9	0.9	1.6	2.3	0.3	2.1	2.3	0.9	1.6	1.3	1.6	1.0	-1.3	2.1	1.8
Systolic blood pressure, automated reading	1.7	5.0	13.1	-2.4	-2.0	-1.6	-2.7	-1.8	-3.2	-2.8	-1.8	-2.0	-2.7	-1.8	-1.8	-2.0	-1.9	-2.0	-2.6	-1.2	-1.6	-3.6	-1.7	-2.9	-1.3
High blood pressure (siblings)	1.7	2.5	4.4	-1.8	-1.7	-1.5	-1.5	-1.8	-1.3	-1.8	-1.6	-1.4	-2.1	-1.8	-1.1	-1.8	-1.9	0.4	-1.4	-1.4	-1.1	-2.0	-0.5	-2.0	-1.2
Number of full brothers	1.7	2.2	3.4	1.7	1.4	1.7	1.5	1.5	1.4	0.3	1.7	1.8	1.7	1.4	1.8	1.1	1.7	1.9	1.6	0.7	1.8	1.4	-0.2	1.2	1.4
Medication: Blood pressure	1.7	3.1	9.4	-1.9	-2.4	-1.5	-2.2	-0.6	-3.1	-1.8	-1.3	-2.3	-0.1	-2.1	-2.6	-1.5	-1.6	-0.9	-1.7	-0.7	-1.0	-2.3	-1.7	-1.4	-0.4
Ever had prostate specific antigen (PSA) test	1.7	1.9	4.4	1.0	2.1	1.0	0.9	0.9	1.8	1.8	1.0	1.7	0.2	2.1	1.6	1.2	1.6	1.4	1.7	1.0	0.9	1.6	1.2	1.4	0.3
Maternal smoking around birth	1.6	2.3	8.5	0.3	1.6	1.4	2.3	1.3	1.6	1.2	1.1	1.3	1.8	1.5	1.0	1.5	1.8	2.9	1.5	-0.1	0.5	2.0	0.6	1.9	0.9
Nervous feelings	1.6	3.0	6.9	-2.3	-1.7	-2.5	-1.6	-2.0	0.3	-1.4	-2.6	-1.9	-1.7	-1.6	-1.6	-2.1	-1.5	1.0	-0.9	-2.0	-1.0	-0.8	1.0	-1.2	-2.6
Illnesses of father: None of the above (group 1)	1.6	1.9	6.5	0.7	1.8	1.3	2.5	0.7	2.5	1.1	0.9	1.2	0.6	2.1	1.2	1.2	2.0	-0.1	0.8	1.1	0.6	1.5	1.1	1.7	0.6
Cholesterol lowering medication	1.6	2.4	5.7	1.1	1.7	1.5	0.1	0.8	1.5	2.3	1.4	2.2	-0.1	1.4	2.0	1.6	1.4	2.0	2.4	1.2	1.6	1.9	0.8	1.6	0.6
Ovarian Cancer	1.5	1.9	9.0	-1.3	0.4	-1.3	-1.9	-1.8	0.8	1.3	-1.6	0.1	-2.4	0.1	0.5	-0.6	-0.4	-1.9	0.3	0.5	-0.6	0.1	3.0	-0.1	-2.7
Age at First Birth	1.5	2.2	7.0	-0.9	-1.5	-1.2	-2.7	-1.3	-0.7	-2.0	-1.9	-1.5	-1.2	-1.5	-1.6	-1.6	-1.3	-1.4	-2.0	0.1	-0.9	-2.1	-0.4	-1.3	-0.9
Waist Hip Ratio (WHR)	1.5	6.8	16.7	1.8	3.1	2.4	1.1	2.3	1.4	3.4	2.8	2.5	1.7	2.8	2.2	3.0	2.9	1.4	4.1	2.7	3.3	3.2	0.6	3.7	1.3
Respiratory disease	1.5	3.4	6.8	-1.6	-2.3	-2.4	-2.6	-1.6	-0.7	-1.7	-1.7	-2.0	-1.1	-2.4	-1.6	-2.4	-2.3	0.6	-1.5	-2.3	-1.4	-1.5	0.0	-2.2	-2.2
Medication: Co-codamol	1.5	1.8	5.1	1.1	1.0	0.9	1.7	-0.1	2.2	1.5	0.6	1.9	-0.5	0.6	2.2	0.7	0.8	1.4	1.7	1.0	0.8	1.9	1.8	1.2	0.2
Diabetes (mother)	1.5	1.9	4.6	-1.6	-1.1	-1.5	-0.6	-1.7	-0.4	-1.9	-1.6	-0.8	-2.2	-1.3	-0.3	-1.6	-1.5	1.1	-0.7	-1.9	-1.0	-0.8	0.9	-1.5	-1.8
Townsend deprivation index at recruitment	1.5	2.1	9.5	-1.0	-0.2	-1.3	0.5	-1.7	2.0	0.8	-1.2	0.2	-2.1	-0.4	0.6	-0.8	-0.8	1.9	-0.4	-2.3	-2.0	1.0	3.1	-0.7	-2.0
Fed-up feelings	1.5	2.7	12.5	-2.7	-1.1	-1.2	-0.3	-0.4	-0.8	-2.9	-1.0	-2.4	-0.8	-0.5	-2.3	-1.9	-0.8	3.5	-1.4	-1.0	-0.2	-2.1	-1.5	-0.9	-1.1
Forced vital capacity (FVC)	1.5	5.6	9.9	-2.3	-2.2	-2.3	-2.9	-2.5	-1.4	-2.5	-3.1	-2.6	-2.8	-2.0	-2.1	-2.4	-2.1	-2.7	-3.1	-1.4	-2.5	-2.7	0.2	-2.4	-2.2
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	4.0	-1.4	-2.0	-1.6	-1.1	-1.2	-0.9	-1.7	-1.6	-1.9	-1.2	-1.9	-1.6	-1.8	-1.8	0.2	-1.4	-0.4	-0.9	-1.7	-0.6	-1.0	-1.2
Birth weight	1.5	3.3	7.6	-1.6	-1.8	-2.0	-1.1	-1.6	-0.8	-2.8	-1.8	-1.6	-1.4	-1.7	-1.0	-2.4	-2.1	-0.7	-2.0	-2.7	-1.9	-1.7	0.1	-2.7	-1.6
Forced vital capacity (FVC), Best measure	1.5	5.6	10.1	-2.3	-2.2	-2.5	-2.8	-2.6	-1.4	-2.6	-3.2	-2.5	-2.9	-2.0	-1.9	-2.6	-2.1	-2.0	-2.9	-1.6	-2.4	-2.6	0.3	-2.5	-2.5
Wheeze or whistling in the chest in last year	1.5	2.7	11.3	0.6	1.5	1.1	1.5	1.4	0.3	1.6	1.4	1.3	1.4	1.5	1.0	1.6	1.9	3.4	2.6	-0.0	1.9	2.4	0.7	2.2	0.2
Asthma (self-reported)	1.5	2.9	6.3	-1.4	-2.4	-2.1	-2.4	-1.3	-1.1	-1.8	-1.3	-1.8	-0.7	-2.5	-1.5	-2.1	-2.5	0.9	-1.4	-1.7	-1.0	-1.4	-0.5	-1.8	-1.6
Angina	1.4	1.9	6.5	0.3	1.2	1.8	1.4	1.8	-0.9	0.5	2.0	1.1	1.1	1.3	0.6	1.6	1.3	2.5	1.1	0.4	0.8	0.6	-1.7	1.1	2.1
Trunk fat-free mass	1.4	7.9	20.9	-1.9	-3.5	-2.6	-0.4	-2.7	-1.2	-4.6	-3.0	-3.2	-2.3	-3.3	-2.3	-3.7	-3.5	-0.3	-4.0	-2.7	-2.7	-3.3	-1.1	-3.3	-1.4
Worrier / anxious feelings	1.4	2.6	10.3	-2.7	-1.5	-1.0	-0.6	-0.2	-2.2	-3.2	-1.2	-2.5	-0.3	-0.7	-2.5	-1.6	-0.5	0.1	-1.2	-0.8	-0.1	-2.5	-2.3	-0.5	-0.9
Trunk predicted mass	1.4	8.1	21.4	-2.0	-3.5	-2.6	-0.4	-2.7	-1.2	-4.6	-3.0	-3.2	-2.3	-3.3	-2.4	-3.8	-3.5	-0.2	-4.0	-2.8	-2.7	-3.3	-1.2	-3.3	-1.4
Had major operations	1.4	1.6	6.3	-1.5	-1.4	-1.3	-0.9	0.0	-1.7	-2.1	-0.9	-1.8	0.4	-1.0	-1.9	-1.2	-0.9	2.5	-0.3	-1.0	0.0	-0.8	-1.2	-0.4	-0.6
Alzheimer’s Disease (in mother)	1.3	1.5	5.8	-1.2	-0.9	-1.1	0.2	-1.3	0.3	-0.7	-1.1	-0.7	-1.1	-1.0	-0.3	-1.4	-1.2	-0.1	-2.0	-2.0	-2.4	-1.0	0.9	-1.8	-0.9
Breast Cancer	1.3	3.1	8.0	1.9	1.7	1.7	1.3	2.0	-0.0	2.1	1.7	1.4	2.2	1.7	0.7	2.3	2.0	0.6	2.3	1.6	1.5	2.1	-0.4	2.8	1.6
Rheumatoid Arthritis	1.3	1.7	5.2	0.6	1.0	1.1	0.2	2.1	-0.1	-0.0	1.3	0.0	2.1	1.5	-0.3	1.0	1.8	1.7	1.6	1.3	2.3	0.9	-1.2	1.8	0.9
Cardiovascular Disease	1.3	4.3	13.1	-2.7	-2.8	-1.8	-2.8	-1.2	-3.6	-2.2	-2.1	-2.6	-1.4	-2.4	-2.9	-1.8	-2.1	0.6	-1.0	0.1	-0.3	-2.7	-1.6	-0.8	-1.4
Lung FEV1/FVC ratio	1.3	6.4	23.1	1.5	1.1	3.3	2.8	3.5	-1.9	-0.4	2.7	0.8	4.8	2.0	-0.2	2.7	2.7	1.2	1.1	2.7	2.6	-0.0	-3.8	2.4	3.9
Pack years adult smoking proportion	1.3	1.9	4.7	0.4	1.2	1.2	1.6	1.6	-0.5	1.6	1.5	1.0	2.1	1.2	0.6	1.5	1.6	2.1	2.2	-0.6	1.5	1.5	-0.8	1.4	0.9
Hair/balding pattern: Pattern 2	1.3	1.7	7.0	-0.6	-1.6	-0.6	0.1	0.0	-2.6	-1.6	-0.6	-1.9	0.5	-1.2	-2.2	-0.8	-0.7	-0.6	-1.6	-0.7	-1.2	-1.7	-2.1	-0.8	0.5
Leg pain on walking	1.3	1.7	4.7	0.7	0.3	1.1	1.4	1.7	-0.4	-0.3	1.2	0.4	1.8	0.8	-0.2	0.9	1.1	2.2	1.7	1.9	1.8	0.6	-1.4	2.1	1.1
Financial situation satisfaction	1.3	1.6	6.9	-1.5	-0.9	0.0	0.6	0.1	-2.3	-2.4	-0.3	-1.1	0.5	-0.5	-1.4	-0.4	-0.5	-1.5	-1.4	0.2	-0.5	-2.6	-2.1	-1.0	0.4
HbA1C	1.2	1.4	5.6	-0.6	-0.1	-0.6	-1.2	-1.6	1.6	0.6	-0.4	0.8	-2.4	-0.4	1.3	-0.7	-0.9	-1.0	-0.7	-1.2	-1.6	0.2	2.1	-1.3	-1.1
BMI	1.2	7.0	15.8	3.0	2.7	3.4	2.0	2.7	0.6	1.6	3.2	2.4	1.7	2.9	1.9	3.0	2.9	1.9	3.1	3.1	4.0	2.3	-1.4	3.0	3.2
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	9.2	-0.1	-0.5	0.6	-0.0	1.0	-1.1	-0.6	0.3	-0.7	1.1	0.1	-1.4	0.5	0.8	3.0	0.4	1.9	1.5	-0.4	-1.8	1.4	1.0
Father’s age at death	1.2	1.6	3.1	-1.3	-1.4	-1.5	-0.8	-0.9	-1.3	-0.8	-1.2	-1.7	-0.0	-1.2	-1.6	-1.4	-1.2	-1.3	-1.5	-1.8	-1.0	-1.3	-0.6	-1.5	-1.0
Asthma	1.2	2.4	5.4	-1.2	-2.2	-1.9	-2.3	-1.1	-1.3	-1.6	-1.1	-1.6	-0.4	-2.3	-1.5	-1.8	-2.3	0.6	-1.1	-1.7	-0.8	-1.3	-0.6	-1.7	-1.4
Arm fat mass (right)	1.2	5.1	11.7	2.4	2.5	2.5	1.8	2.3	0.8	1.1	2.5	2.0	1.7	2.7	1.7	2.4	2.4	2.5	3.0	2.2	3.4	2.2	-0.8	2.6	2.0
Pulse wave peak to peak time	1.2	1.4	4.4	-0.0	0.2	-0.3	0.3	-1.5	1.9	1.0	-0.8	1.3	-0.9	-0.4	2.1	-0.6	-0.9	-1.2	-0.8	-1.5	-2.0	-0.2	1.8	-1.7	-1.1
Migraine (self-reported)	1.2	1.5	3.8	-0.8	-1.3	-1.3	-0.1	-1.7	0.5	-0.7	-1.2	-0.3	-1.1	-1.8	0.3	-1.6	-1.8	-0.3	-0.9	-2.0	-1.6	-0.5	0.9	-1.7	-1.2
Breast cancer (self-reported)	1.2	1.4	3.6	-1.1	-1.0	-1.7	-1.6	-1.5	0.9	-0.6	-1.2	-1.1	-1.1	-1.2	-0.7	-1.4	-1.1	-1.0	-0.8	-1.5	-1.3	-0.2	1.4	-0.8	-1.9
Pack years of smoking	1.2	1.8	5.5	0.2	1.0	0.9	1.2	1.5	-0.8	1.6	1.2	0.8	2.1	1.1	0.4	1.4	1.5	2.2	2.3	-0.5	1.6	1.6	-0.7	1.6	0.6
Depressed Affect (Nagel 2018)	1.1	2.4	6.2	-2.5	-1.1	-1.6	-0.6	-1.0	-0.3	-2.5	-1.5	-2.0	-1.5	-0.7	-1.7	-2.1	-1.4	2.2	-1.7	-0.8	-1.1	-2.1	-0.4	-1.1	-1.5
Prostate Cancer	1.1	1.5	5.8	1.4	1.4	1.0	1.4	-0.4	1.8	1.2	0.5	2.0	-0.7	0.8	2.4	0.9	1.0	-1.6	0.6	-0.1	0.0	1.3	1.8	0.2	0.1
Blood Platelet Count	1.1	12.4	34.1	2.8	3.5	5.3	5.8	4.5	0.8	1.1	4.9	3.4	4.4	3.8	2.2	4.2	3.7	0.0	1.7	1.8	2.4	1.5	-3.2	2.7	5.6
Hayfever, allergic rhinitis or eczema	1.1	2.4	5.8	-0.8	-1.7	-2.0	-0.3	-2.4	1.3	-0.6	-2.0	-0.8	-2.2	-2.1	-0.3	-2.0	-2.3	-0.8	-1.3	-0.5	-1.6	-0.4	1.9	-0.8	-2.0
Past tobacco smoking	1.1	2.1	4.2	1.9	1.6	2.1	2.0	1.5	0.6	0.2	1.5	1.6	1.7	1.8	1.3	1.8	1.8	-0.6	0.6	1.9	1.2	0.4	-0.4	0.6	1.7
Medication: Lansoprazole	1.1	1.2	2.7	0.3	1.4	0.7	0.6	0.6	1.3	1.2	0.8	1.4	0.1	1.2	1.4	1.0	1.2	1.6	1.6	0.5	0.3	1.6	1.2	1.5	-0.2
Pulse wave Arterial Stiffness index	1.1	1.3	6.6	-0.6	-0.9	-0.4	-0.7	0.8	-2.0	-1.6	0.0	-1.9	0.2	-0.3	-2.6	-0.2	0.2	1.4	0.1	0.9	1.3	-0.3	-1.7	1.1	0.5
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	4.0	-1.7	-1.4	-1.6	-2.0	-0.9	-1.2	-0.6	-1.5	-1.6	-0.4	-1.3	-1.6	-1.1	-1.0	-0.3	-0.7	-0.6	-0.7	-0.9	0.0	-0.5	-1.4
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	6.3	1.7	1.9	1.2	1.7	0.6	2.5	1.1	1.1	1.6	0.4	1.8	1.8	1.3	1.5	-0.2	1.0	0.3	0.5	1.9	1.3	1.0	0.4
Mean time to correctly identify matches	1.1	2.0	7.3	0.2	0.5	1.4	0.1	2.1	-1.3	-1.4	1.2	-0.8	1.6	1.4	-1.5	1.1	1.6	0.5	0.3	2.4	2.0	-0.9	-2.7	1.0	1.7
Leg fat mass (right)	1.1	4.4	12.3	2.2	2.1	2.6	1.4	2.2	0.3	0.7	2.3	1.7	1.2	2.3	1.2	2.3	2.2	2.1	2.8	2.6	3.5	1.8	-1.2	2.6	2.2
Supplements: Vitamin C	1.1	1.3	4.0	0.1	1.0	0.7	0.1	1.4	-0.2	0.7	1.1	0.2	1.3	1.3	-0.1	0.9	1.3	1.8	1.9	0.9	1.8	1.3	-0.2	2.0	0.2
Commuting to job workplace: Walk	1.1	1.2	4.3	-0.5	-1.4	-1.4	-0.1	-0.7	-0.9	-1.0	-0.9	-1.1	-0.6	-1.3	-1.0	-1.3	-1.4	-1.1	-1.2	-2.1	-1.3	-0.9	-0.6	-1.2	-0.6
Arm fat mass (left)	1.1	4.5	12.7	2.2	2.3	2.3	1.4	2.0	0.9	0.9	2.3	1.8	1.3	2.5	1.6	2.1	2.2	2.3	3.0	2.3	3.6	2.1	-0.7	2.5	1.8
Average weekly spirits intake	1.0	1.2	3.9	-0.6	-1.0	-1.4	-1.5	-1.1	-0.7	-0.9	-1.0	-0.8	-1.2	-1.3	-0.5	-1.1	-1.7	-0.5	-1.0	-1.4	-1.2	-0.8	0.2	-2.0	-0.8
Hair/balding pattern: Pattern 3	1.0	1.5	5.8	0.7	0.8	1.4	0.5	1.6	0.2	-0.3	1.4	0.5	1.2	1.1	0.0	1.2	1.4	1.5	1.0	2.4	1.8	0.5	-1.0	1.6	1.6
Prospective memory result	1.0	1.2	4.7	0.5	1.5	1.0	-0.7	0.9	0.7	0.6	0.9	0.8	0.1	1.8	0.5	1.1	1.3	-0.2	1.4	2.2	1.8	0.6	0.2	1.1	0.4
Medication: Ventolin 100micrograms inhaler	1.0	1.3	3.5	-0.5	-1.6	-1.3	-1.4	-1.1	-0.3	-1.7	-1.1	-0.7	-0.6	-1.9	-0.4	-1.4	-1.8	-1.2	-0.9	-1.0	-0.7	-1.0	-0.0	-1.1	-1.1
Family relationship satisfaction	1.0	1.2	5.7	-1.7	-0.4	-0.9	0.2	-0.8	0.5	-2.4	-1.0	-1.2	-1.1	-0.2	-1.0	-1.4	-0.5	1.4	-1.2	-1.3	-0.6	-1.2	-0.2	-1.2	-0.8
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	4.7	0.5	-0.5	-1.3	-1.1	-1.0	0.4	-0.4	-1.1	-0.6	-0.6	-0.7	-0.1	-1.0	-1.2	-1.9	-1.4	-1.5	-1.4	-0.7	0.5	-2.2	-0.9
Guilty feelings	1.0	1.6	4.4	-1.7	-1.2	-1.0	-0.9	-0.4	-1.0	-2.1	-1.3	-1.9	-0.5	-0.9	-2.0	-1.3	-0.9	-1.2	-1.5	-0.1	-0.5	-2.0	-1.0	-0.5	-0.7
Eye problems/disorders: Glaucoma	1.0	1.2	5.6	-0.6	-1.0	-0.9	-0.5	-1.2	0.1	-0.2	-0.8	-0.5	-0.2	-1.2	-0.0	-1.2	-1.4	-2.4	-1.6	-0.2	-1.2	-1.6	0.4	-1.7	-1.0
Verbal and Numeric Reasoning (VNR)	0.9	2.1	9.4	0.7	0.0	1.5	0.6	2.2	-1.9	-1.0	1.6	-0.5	2.1	0.7	-1.3	1.0	1.2	2.4	-0.6	-0.2	0.5	-0.6	-3.1	-0.5	2.6
HDL Cholesterol	0.9	1.4	3.9	-0.3	-1.3	-1.7	-1.6	-1.6	-0.3	0.2	-2.0	-0.9	-1.6	-1.4	-0.5	-1.4	-1.3	-0.0	-0.6	-0.9	-1.2	-0.2	1.6	-0.8	-1.8
Allergy or Eczema	0.9	2.3	6.9	-0.1	-1.4	-2.1	-0.1	-2.3	1.7	-0.1	-2.0	-0.6	-1.6	-1.9	0.0	-1.8	-2.1	-1.6	-1.2	-0.3	-1.9	0.1	2.6	-0.5	-2.1
Taking other prescription medications	0.9	1.4	7.2	-1.9	-1.5	-1.0	-0.9	-0.4	-1.5	-1.6	-0.6	-1.4	-0.6	-1.3	-1.5	-1.1	-1.0	2.7	0.0	0.0	0.1	-1.0	-1.2	0.4	-0.6
Serious illness, injury or assault to yourself	0.9	1.1	2.6	1.0	0.6	1.0	1.6	0.3	1.5	0.8	1.0	1.6	0.3	0.1	1.6	0.8	0.3	1.4	1.4	0.1	0.9	1.6	0.8	1.0	0.4
Supplements: Glucosamine	0.9	1.2	3.2	1.0	0.9	1.0	1.1	1.3	-0.4	0.8	0.9	0.6	1.8	1.0	0.4	0.9	1.4	1.2	1.5	0.3	0.9	1.5	-0.5	1.6	1.1
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	2.5	-1.1	-1.4	-1.2	-0.3	-0.8	-1.3	-0.7	-1.3	-1.5	-0.1	-1.1	-1.6	-1.1	-0.9	0.4	-1.0	-0.7	-1.2	-0.9	-0.1	-0.6	-0.7
Medication: Ramipril	0.9	1.1	7.1	0.2	-0.3	0.6	0.0	1.4	-2.7	0.1	0.7	-0.0	1.9	-0.1	-0.6	0.8	-0.0	1.2	0.9	0.5	0.8	-0.1	-2.0	0.8	1.5
Fluid intelligence score	0.9	1.8	9.9	0.6	-0.5	0.9	0.6	1.8	-1.9	-1.4	1.2	-0.9	1.7	0.1	-1.4	0.3	0.6	2.1	-0.7	-0.4	0.4	-0.9	-3.1	-0.6	2.2
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	6.7	-0.0	0.9	1.3	2.1	1.2	0.1	-0.6	1.3	0.4	1.1	1.2	0.5	0.7	1.3	2.6	1.2	1.2	1.9	0.1	-1.1	1.1	0.8
Depression (self-reported)	0.9	1.1	5.0	0.3	1.1	0.2	1.3	0.2	1.1	1.5	0.5	1.1	0.2	0.9	1.3	0.7	0.7	2.2	1.6	-0.7	0.5	1.8	1.1	0.9	-0.1
Length of working week for main job	0.9	0.9	4.1	0.2	0.9	0.8	0.3	1.2	-0.3	0.1	0.6	-0.2	0.9	1.5	-0.4	0.7	1.6	2.0	0.8	1.3	1.3	0.6	-0.5	1.5	0.5
Eye problems/disorders: None of the above	0.9	1.0	3.1	0.7	1.2	1.0	0.5	1.2	-0.1	1.8	0.8	0.6	1.0	1.4	0.1	1.3	1.7	0.7	1.1	0.1	0.5	1.4	-0.0	1.1	0.8
Knee pain experienced in last month	0.9	1.5	4.8	1.2	1.1	0.9	0.4	0.4	2.1	0.4	0.8	1.3	-0.5	0.8	1.3	0.8	0.9	1.0	1.9	1.3	1.5	1.8	0.7	2.2	0.5
Friendships satisfaction	0.9	1.1	3.4	-1.1	-0.8	-0.9	0.5	-1.2	0.3	-1.7	-1.1	-0.8	-1.4	-0.7	-0.4	-1.4	-0.9	1.1	-1.5	-0.6	-1.0	-1.4	0.2	-1.8	-0.9
Whole body water mass	0.9	5.3	16.2	-1.4	-2.9	-2.1	-0.5	-2.2	-1.2	-4.0	-2.3	-2.8	-1.9	-2.7	-2.1	-3.1	-2.9	-0.3	-3.1	-1.9	-1.8	-2.7	-1.2	-2.6	-1.0
Alcohol drinker status: Never	0.9	1.1	3.3	-0.6	-0.8	-0.7	-0.1	-1.2	1.3	-0.9	-0.7	-0.3	-1.6	-1.1	0.3	-1.0	-1.3	0.6	-1.5	-1.5	-1.6	-0.9	0.4	-1.8	-0.7
Ever depressed for a whole week	0.9	1.1	11.0	-0.6	0.2	0.2	1.1	1.1	-0.9	-1.0	0.0	-0.8	1.2	0.7	-1.2	0.1	1.0	3.3	0.1	-0.5	0.3	-0.0	-1.2	0.9	0.5
Leg fat mass (left)	0.9	3.5	11.3	1.7	1.7	2.1	1.0	1.9	0.1	0.2	1.9	1.2	0.9	2.0	0.8	1.9	2.0	2.4	2.6	2.4	3.4	1.5	-1.2	2.5	1.8
Alzheimer’s Disease (in father)	0.8	0.9	3.1	0.7	0.6	1.1	0.2	1.5	-1.3	0.0	1.3	0.6	1.6	0.6	0.1	1.1	0.6	-0.0	0.9	-0.1	1.0	0.3	-1.8	0.2	1.6
Blood White Count	0.8	6.1	13.0	2.1	2.7	3.6	2.1	2.8	1.7	1.7	2.7	2.5	2.1	2.9	1.8	3.0	2.8	0.7	1.8	3.0	2.4	1.4	-1.5	2.9	3.5
Medication for hormone replacement therapy	0.8	0.9	3.2	0.2	1.2	0.5	1.3	0.4	1.8	0.9	0.4	0.9	0.8	1.0	1.1	0.3	1.0	1.1	1.2	-0.3	0.8	1.6	1.1	1.1	0.0
Age when periods started (menarche)	0.8	1.9	7.3	0.6	1.6	1.7	0.1	1.1	0.7	1.2	1.2	1.4	0.6	1.6	1.1	1.5	1.6	-1.7	1.4	2.7	1.6	0.6	0.0	2.2	0.9
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	5.1	0.2	0.1	0.7	1.8	1.1	-0.1	-1.6	0.4	-0.3	1.3	0.4	-0.7	0.3	0.8	2.2	-0.2	-0.4	0.2	-0.2	-1.7	0.7	1.2
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.3	-1.0	-1.2	-0.8	-0.9	-0.6	-1.0	-1.5	-1.1	-1.2	-0.3	-1.0	-1.2	-1.0	-0.9	-0.6	-1.4	-0.0	-0.9	-1.4	-0.3	-0.4	-0.4
Mouth/teeth dental problems: Dentures	0.8	1.3	4.1	1.4	0.9	0.8	1.5	0.7	1.6	0.8	1.0	1.4	0.5	0.5	1.4	0.8	0.8	1.6	1.3	0.1	0.7	2.0	0.8	1.3	0.7
Lung cancer (father)	0.8	0.9	6.4	0.5	0.7	1.3	2.5	1.1	-0.2	-0.2	1.0	0.4	0.7	1.0	0.2	0.8	0.9	0.5	-0.0	0.3	0.1	-0.0	-1.3	0.7	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	5.6	-1.5	-1.4	-1.2	-1.3	-1.3	-1.7	-2.0	-2.0	-1.8	-1.2	-1.1	-1.6	-1.3	-1.1	-1.7	-2.4	-1.0	-2.0	-2.1	-0.5	-1.5	-1.0
Glaucoma (self-reported)	0.8	1.0	2.6	-0.6	-1.0	-0.9	-0.5	-1.2	-0.3	-0.4	-1.0	-0.5	-0.2	-1.2	0.0	-1.1	-1.3	-1.5	-1.3	0.0	-1.2	-1.6	0.4	-1.4	-1.1
Qualifications: College or University degree	0.8	2.6	5.3	-0.4	-2.3	-1.8	-0.7	-1.5	-1.0	-1.7	-1.4	-1.8	-1.3	-2.3	-1.4	-2.2	-2.3	-0.6	-2.0	-1.8	-1.7	-1.4	-0.7	-2.1	-0.6
Mouth/teeth dental problems: Loose teeth	0.8	1.0	3.3	0.1	1.1	0.9	1.8	0.9	0.1	0.5	0.9	0.9	1.7	1.1	0.9	1.0	1.0	0.7	1.3	0.5	0.7	1.0	0.1	1.3	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	5.1	0.9	0.2	-0.4	-0.5	-0.9	0.6	1.9	-0.6	1.1	-0.5	-0.4	1.7	-0.1	-0.3	-1.1	0.8	0.3	-0.3	1.3	2.3	0.6	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	3.1	0.3	1.6	0.9	-0.5	0.6	0.6	0.8	0.4	0.9	-0.6	1.8	0.6	1.3	1.8	0.2	0.9	1.1	0.7	0.9	0.8	1.4	0.2
Whole body fat-free mass	0.8	4.8	15.4	-1.4	-2.8	-2.0	-0.4	-2.0	-1.2	-3.9	-2.2	-2.7	-1.8	-2.5	-2.0	-2.9	-2.7	-0.2	-2.9	-1.8	-1.6	-2.6	-1.3	-2.4	-0.9
Medication for cholesterol	0.8	1.2	4.1	-0.1	-1.1	-0.3	0.8	0.3	-1.2	-1.4	0.1	-1.3	0.8	-0.7	-1.5	-0.5	-0.7	-2.0	-2.0	-0.5	-1.2	-1.4	-1.8	-1.0	0.9
Unable to work because of sickness or disability	0.8	1.0	2.9	0.6	0.5	0.8	1.3	0.4	1.0	1.6	0.8	1.5	0.7	0.4	1.6	0.9	0.7	1.7	1.4	-0.1	0.3	1.3	0.9	0.8	0.2
Supplements: Calcium	0.8	0.9	3.1	-1.1	-1.1	-1.4	-1.1	-1.1	-0.7	-0.3	-1.8	-1.1	-0.9	-1.1	-1.1	-1.1	-0.9	1.0	0.0	-0.1	-0.4	-0.4	0.5	-0.0	-1.4
Intelligence (Savage-Jansen 2018)	0.7	2.1	11.0	0.4	-0.2	1.4	1.0	1.8	-1.9	-1.3	1.5	-0.4	1.9	0.4	-0.8	0.7	0.8	2.5	-1.0	-0.9	-0.1	-1.0	-3.3	-1.0	2.5
Major Depression (MDD)	0.7	0.8	6.7	-0.0	0.4	-0.1	0.2	0.2	1.3	0.0	-0.2	-0.2	0.1	0.6	-0.1	-0.1	0.7	2.6	1.0	1.1	1.4	1.0	0.9	1.2	-0.5
Tanning	0.7	8.3	14.3	2.7	3.7	3.2	3.8	2.4	2.3	3.7	3.2	3.7	2.3	3.5	3.6	3.3	3.5	1.5	3.0	0.5	2.0	3.4	1.2	1.7	1.9
Number of treatments/medications taken	0.7	1.2	11.6	-1.6	-0.9	-0.9	-1.1	-0.4	-1.4	0.0	-0.8	-0.5	-0.3	-1.0	-0.5	-0.5	-0.4	3.4	1.3	0.0	0.3	0.0	0.0	1.0	-1.2
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.4	-0.6	-1.1	-1.1	-0.2	-0.8	-1.1	-1.2	-1.3	-1.3	-0.4	-0.8	-0.9	-1.6	-0.8	0.6	-1.0	-1.1	-0.7	-0.9	-0.5	-1.0	-0.7
Severe depression (siblings)	0.7	0.8	3.6	-1.5	-0.5	-0.1	-0.1	0.4	-1.8	-0.4	-0.2	-0.9	0.5	0.0	-1.1	-0.1	0.1	1.9	-0.4	-0.7	-0.2	-1.3	-1.4	-0.8	-0.0
Average weekly fortified wine intake	0.7	0.8	2.1	1.3	1.1	1.0	0.7	0.2	1.5	0.7	0.6	1.3	-0.1	0.7	1.4	0.8	0.9	-0.9	0.4	0.3	0.3	1.0	0.7	0.4	0.7
Medication: Levothyroxine sodium	0.7	1.1	6.8	-0.5	-0.6	-0.1	-0.8	1.0	-2.6	-1.7	-0.1	-1.1	0.8	-0.2	-1.6	-0.1	0.0	0.6	0.9	0.4	1.1	-0.4	-2.1	1.0	0.5
Trunk fat mass	0.7	2.8	11.3	1.5	1.5	1.5	0.4	1.6	0.4	0.3	1.6	0.9	0.8	1.7	0.7	1.3	1.7	2.8	2.7	2.0	3.4	1.7	-0.7	2.3	1.0
Number of live births	0.7	1.0	4.6	0.5	0.8	0.9	2.1	1.3	0.7	0.5	1.1	0.3	2.1	0.8	0.0	0.9	0.7	0.5	0.3	0.7	0.1	0.9	-0.3	1.8	1.2
Exposure to tobacco smoke at home	0.7	0.8	3.5	0.9	-0.2	1.0	0.4	1.0	-1.1	-0.0	0.8	0.2	0.8	-0.4	-0.1	0.8	0.0	-0.7	0.2	1.3	1.0	-0.2	-1.9	0.6	1.8
Breastfed as a baby	0.7	0.8	4.4	0.5	1.5	1.0	0.5	0.6	1.0	0.5	1.1	1.2	0.5	1.2	1.2	1.0	0.5	-2.1	-0.1	0.2	0.2	-0.1	0.1	-0.5	0.7
Loud music exposure frequency	0.7	0.7	5.9	-0.2	-0.5	0.1	0.2	0.1	-1.9	-0.8	-0.3	-0.5	0.2	-0.5	-0.8	0.1	-0.3	-2.4	-0.5	0.7	-0.3	-1.0	-1.3	0.9	0.5
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.1	-1.4	-1.1	-0.7	-0.4	-0.4	-1.8	-1.5	-0.7	-1.4	-0.1	-1.0	-1.4	-0.8	-0.7	-0.2	-1.3	-1.1	-1.1	-1.3	-0.9	-1.0	-0.3
Arm fat-free mass (right)	0.7	3.8	12.5	-1.4	-2.4	-1.6	-0.8	-1.9	-1.1	-3.5	-2.1	-2.4	-2.0	-2.2	-1.8	-2.5	-2.4	-0.4	-2.5	-1.0	-1.3	-2.5	-1.0	-1.9	-0.9
Medication for pain relief, constipation, heartburn	0.7	1.1	4.1	0.3	-0.3	-1.1	-1.1	-1.5	0.7	-0.2	-1.0	-0.1	-1.9	-0.5	0.5	-1.0	-0.9	-2.0	-0.6	0.0	-0.4	-0.2	1.7	-1.5	-1.5
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.6	0.1	1.0	1.1	-0.2	0.6	0.3	0.8	0.8	0.9	0.6	1.0	0.8	1.1	1.0	0.1	1.3	1.6	1.3	0.5	0.2	1.1	0.2
Number of self-reported non-cancer illnesses	0.7	1.1	6.1	-1.5	-1.5	-1.0	-0.0	-0.5	-1.6	-1.2	-0.5	-1.0	-0.3	-1.4	-0.8	-1.2	-1.3	2.5	-0.1	-0.5	-0.3	-0.9	-0.7	-0.3	-0.7
Miserableness	0.7	1.2	6.2	-2.5	-0.4	-1.0	-0.0	-0.5	-0.6	-1.6	-0.9	-1.3	-0.7	-0.0	-1.2	-1.1	-0.3	1.5	-1.0	-1.1	-1.0	-1.4	0.0	-0.5	-1.5
Body Mass Index (BMI) (2010)	0.6	0.8	2.2	0.4	1.1	0.7	0.3	0.8	1.5	0.5	1.0	0.9	1.0	1.2	0.8	0.8	1.3	0.9	0.8	0.2	0.8	1.1	0.5	0.8	0.3
Coronary Artery Disease (CAD)	0.6	0.7	2.6	-1.1	-0.1	0.6	0.7	0.9	-0.4	-1.4	0.8	-0.5	0.6	0.4	-0.8	0.3	0.5	0.0	-1.1	0.6	-0.2	-1.6	-1.6	-0.2	0.6
Hypothyroidism (self reported)	0.6	1.5	6.7	-1.0	-1.3	-1.3	-1.4	0.2	-2.6	-1.5	-1.1	-1.9	0.2	-1.1	-2.0	-1.0	-0.7	1.6	0.4	-1.1	0.0	-0.3	-1.3	0.1	-0.6
Sensitivity / hurt feelings	0.6	1.0	3.2	0.1	0.2	0.9	1.8	1.4	-0.7	-0.4	0.8	-0.1	1.5	0.5	-0.5	0.8	0.9	1.6	0.8	0.4	1.1	0.3	-1.7	1.5	1.2
Ever had hysterectomy (womb removed)	0.6	0.6	3.2	0.8	0.5	0.6	1.5	-0.3	1.6	0.7	0.2	1.5	-0.3	0.2	1.8	0.3	-0.1	0.2	0.2	-0.1	-0.6	0.6	0.9	0.0	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	4.5	0.9	1.0	0.4	1.0	-0.3	1.9	2.0	0.3	1.7	-0.1	0.6	1.8	0.9	0.4	-0.9	1.0	0.0	-0.1	1.7	2.1	0.6	-0.2
Stomach or abdominal pain in last month	0.6	0.7	2.0	-1.3	-0.9	-1.1	-0.1	-0.6	0.0	-1.4	-0.9	-1.1	-0.7	-0.8	-0.8	-1.1	-1.1	0.9	-0.2	-0.2	-0.1	-0.6	0.2	-0.0	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	5.4	-1.8	-0.9	-0.6	0.5	0.1	-1.2	-1.2	-0.4	-1.4	-0.0	-0.3	-1.7	-0.8	-0.1	2.3	-0.2	0.2	0.1	-0.8	-0.8	0.7	-0.4
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	5.1	-1.3	-1.4	-0.8	-1.6	-0.9	-1.8	-1.7	-1.7	-1.8	-0.7	-1.0	-1.8	-0.9	-0.8	-1.7	-2.3	-0.5	-1.5	-2.0	-0.9	-1.2	-0.5
Birth weight of first child	0.6	1.0	3.5	1.2	-0.6	-0.6	0.0	-1.2	1.5	-0.9	-0.6	0.4	-0.8	-1.1	1.0	-1.3	-1.4	0.2	-1.0	-1.5	-1.2	0.1	1.0	-1.9	-0.5
Gout (self-reported)	0.6	0.8	7.1	0.3	0.4	0.4	-0.7	1.2	-1.2	0.2	0.5	-0.2	0.9	0.7	-0.4	0.5	0.9	2.7	0.9	0.6	1.1	0.5	-0.8	0.8	0.7
Medication: Ibuprofen	0.6	0.7	2.4	-0.5	-0.0	0.7	1.4	1.1	-0.7	-0.3	0.6	-0.2	1.6	0.4	-0.8	0.8	0.8	1.3	0.6	0.1	0.6	0.3	-1.1	1.2	0.8
Whole body fat mass	0.6	2.7	10.6	1.4	1.6	1.6	0.4	1.6	0.5	0.2	1.6	0.9	0.7	1.9	0.7	1.4	1.7	2.3	2.6	2.2	3.2	1.5	-0.8	2.3	1.1
Arm predicted mass (right)	0.6	3.0	10.5	-0.9	-2.2	-1.3	-0.3	-1.6	-1.1	-3.2	-1.8	-2.1	-1.6	-2.1	-1.5	-2.2	-2.2	-0.2	-2.3	-0.9	-1.2	-2.1	-1.1	-1.6	-0.5
Overall health rating	0.6	1.3	7.8	-1.3	-0.7	0.2	-0.2	0.9	-1.8	-1.0	0.2	-0.7	0.8	-0.2	-1.2	0.3	0.3	2.8	1.3	1.2	1.7	-0.4	-1.5	1.5	0.1
Qualifications: nursing, teaching	0.6	1.0	5.5	1.5	0.4	0.1	1.4	-0.7	2.4	0.8	-0.1	1.0	-0.4	-0.1	1.3	0.2	-0.0	0.2	-0.2	-0.3	-1.2	1.5	1.9	0.4	0.3
Eye problems/disorders: Cataract	0.6	0.7	3.1	-0.7	-1.1	-0.4	-0.9	-0.7	-0.6	-1.8	-0.5	-0.9	-0.8	-1.0	-0.7	-0.9	-1.1	0.0	-0.9	0.8	-0.1	-1.5	-0.5	-0.7	-0.3
Commuting to job workplace: Public transport	0.6	0.7	3.5	1.2	0.1	0.9	0.7	1.2	-1.1	0.3	1.3	0.1	1.2	0.1	-0.1	0.6	0.2	0.3	0.0	0.2	0.4	0.3	-1.6	0.1	1.9
Myopia	0.6	0.9	2.6	-1.4	-0.2	-0.8	-1.6	-1.0	-1.3	-0.8	-0.9	-0.5	-1.3	0.0	-0.2	-0.6	-0.1	-1.1	-0.7	-0.6	-1.0	-0.9	0.7	-1.1	-1.3
Ulcerative Colitis (UC)	0.5	0.9	3.5	-0.6	-1.3	-1.1	-0.7	-0.8	-0.4	-1.9	-1.0	-1.3	0.0	-1.3	-1.3	-1.2	-1.0	-0.2	-1.2	-0.7	-0.7	-0.9	-0.4	-0.8	-0.7
Triglycerides	0.5	0.9	3.1	0.2	1.1	1.0	0.1	0.1	1.8	0.5	1.1	1.2	-0.5	0.9	1.2	0.7	1.1	0.6	0.6	1.5	1.3	0.6	0.5	0.8	0.5
Chronotype (morning person)	0.5	1.1	3.9	-0.4	-1.2	-1.2	-0.7	-1.0	-0.3	-0.9	-0.9	-0.7	-1.0	-1.6	-0.3	-1.2	-1.7	-2.0	-0.8	-1.7	-1.3	-0.2	0.4	-1.2	-0.7
Had other major operations	0.5	0.6	5.5	-0.8	-0.4	-0.7	0.5	-0.6	0.8	-0.7	-0.5	-0.4	-0.6	-0.1	-0.1	-1.0	-0.1	2.3	0.1	-1.0	-0.3	0.5	0.8	0.0	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	3.6	0.9	1.1	0.5	1.4	-0.3	1.9	1.9	0.4	1.6	-0.1	0.6	1.6	1.1	0.4	-0.9	0.8	-0.3	-0.4	1.8	1.9	0.6	0.0
Qualifications: None of the above	0.5	1.1	3.6	0.6	0.8	0.1	1.0	-0.1	1.9	1.1	0.3	1.1	0.4	0.5	1.2	0.3	0.3	0.4	1.8	1.2	1.7	1.5	1.4	1.6	-0.5
Medication: Simvastatin	0.5	0.7	4.0	0.5	0.7	0.6	-0.1	0.3	-0.5	2.0	0.1	1.1	0.4	0.5	0.9	0.9	0.7	0.9	1.3	1.6	0.4	0.5	0.7	1.0	-0.0
Noisy workplace	0.5	0.6	3.1	0.2	0.6	0.6	0.1	0.7	0.3	0.0	0.2	0.3	0.1	0.8	-0.2	0.8	0.9	1.0	0.9	1.2	0.9	0.9	0.1	1.8	0.6
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	6.8	-0.6	-0.9	-0.6	-0.7	0.5	-2.6	-1.6	-0.5	-1.3	0.5	-0.7	-1.5	-0.6	-0.4	0.6	0.4	-0.3	0.3	-0.6	-1.7	0.3	-0.0
Emphysema/chronic bronchitis	0.5	0.6	2.5	-0.1	0.7	0.5	0.2	0.4	0.6	0.7	0.5	0.7	0.3	0.5	0.8	0.7	0.5	1.3	1.6	0.5	1.3	0.8	0.3	0.8	-0.3
Medication: Omeprazole	0.5	0.6	3.1	-0.6	0.4	0.6	-0.4	1.1	-1.1	0.5	0.9	0.1	0.8	0.6	-0.3	0.7	0.8	1.8	0.9	0.2	0.8	0.1	-0.9	0.8	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	5.1	-0.7	-0.2	-0.2	-0.6	0.4	0.1	-0.1	-0.1	-0.4	-0.2	0.1	-0.4	-0.3	0.1	2.3	1.2	0.7	1.0	0.3	-0.3	1.4	-0.5
Leg fat-free mass (right)	0.5	2.7	10.1	-0.9	-2.0	-1.5	-0.7	-1.4	-1.0	-3.2	-1.5	-2.2	-1.4	-1.8	-1.7	-2.3	-2.0	-0.1	-1.9	-1.2	-0.6	-2.0	-1.3	-1.8	-0.7
Handedness (chirality/laterality): Left-handed	0.5	0.6	3.9	-0.1	-0.2	0.1	-0.1	0.1	0.1	-1.5	0.3	-0.6	-0.3	0.2	-0.5	-0.5	0.2	0.9	-1.6	-0.6	-0.2	-1.4	-0.9	-2.0	0.0
Long-standing illness, disability or infirmity	0.5	0.8	9.3	-0.2	-0.7	0.0	0.6	0.5	-1.1	-0.9	0.3	-0.2	0.4	-0.7	-0.4	-0.0	-0.5	3.1	1.0	-0.3	0.6	0.4	-1.1	1.0	0.4
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.5	-0.6	-1.1	-1.6	-0.4	-1.1	0.3	0.1	-1.2	-0.9	-0.1	-1.2	-0.6	-1.2	-1.0	-1.3	0.1	0.0	-0.2	0.2	1.3	0.4	-1.6
Medication: Aspirin	0.5	0.7	3.4	-0.9	-0.5	0.0	-0.7	0.7	-1.8	0.2	0.2	-0.7	0.4	-0.2	-1.1	-0.0	0.1	1.8	0.1	-0.5	0.2	-0.8	-1.9	-0.1	0.6
Leg predicted mass (right)	0.5	2.8	10.4	-1.0	-2.1	-1.5	-0.8	-1.4	-1.1	-3.2	-1.5	-2.3	-1.3	-1.8	-1.8	-2.3	-2.0	-0.1	-1.9	-1.2	-0.6	-2.0	-1.4	-1.8	-0.7
Ever taken oral contraceptive pill	0.5	0.5	2.0	-0.4	-0.4	-0.8	-0.5	-0.9	0.3	0.1	-0.7	-0.2	-0.8	-0.6	0.1	-0.6	-0.5	-1.4	-0.5	-1.0	-1.2	-0.0	1.1	-0.6	-0.9
High cholesterol (Self-reported)	0.5	0.8	3.2	0.4	0.7	0.3	0.1	-0.5	1.0	1.8	0.0	1.4	-0.8	0.3	1.4	0.5	0.2	-0.3	1.1	1.2	0.6	0.7	1.7	0.8	-0.6
Basal metabolic rate	0.5	2.8	11.4	-0.8	-2.1	-1.4	-0.0	-1.5	-0.8	-3.4	-1.6	-2.1	-1.4	-1.9	-1.5	-2.3	-2.1	0.3	-2.1	-1.4	-0.9	-1.9	-1.2	-1.8	-0.6
Arm fat-free mass (left)	0.5	2.7	10.3	-0.8	-2.2	-1.3	0.1	-1.4	-1.0	-3.2	-1.6	-2.0	-1.2	-2.0	-1.5	-2.1	-2.1	0.4	-2.1	-1.1	-1.0	-1.9	-1.2	-1.5	-0.4
Number of operations (self-reported)	0.5	0.7	6.9	-1.0	-0.7	-0.8	0.5	-0.5	0.6	-0.8	-0.6	-0.5	0.3	-0.7	-0.3	-1.1	-0.4	2.6	0.3	-0.8	-0.0	0.4	0.4	0.5	-0.8
Arm predicted mass (left)	0.5	2.6	10.6	-0.7	-2.1	-1.2	0.3	-1.3	-1.0	-3.3	-1.5	-2.0	-1.1	-1.9	-1.5	-2.0	-2.0	-0.0	-2.2	-1.1	-1.1	-2.0	-1.3	-1.5	-0.2
Bipolar Disorder or Schizophrenia	0.4	1.0	2.3	0.3	1.5	0.8	0.5	0.1	1.4	1.2	0.2	1.3	0.3	1.5	1.3	1.1	1.2	-0.8	0.8	-0.2	0.3	1.4	1.5	0.7	-0.1
Neuroticism (2016)	0.4	0.6	3.9	-0.4	-0.9	-0.6	0.6	-0.7	-0.5	-1.3	-1.0	-0.7	-0.6	-0.9	-0.3	-1.2	-0.5	2.0	-0.3	-0.2	-0.2	-0.2	0.3	0.0	-0.4
Lung FVC	0.4	1.8	4.2	1.6	1.9	1.4	-1.1	0.8	0.4	2.0	0.6	1.4	-0.3	1.9	1.2	1.7	1.8	-1.0	1.3	2.0	1.2	1.2	0.6	1.4	0.8
Medication: Metformin	0.4	0.5	2.5	0.5	0.2	0.1	-0.1	0.4	0.1	0.8	0.1	0.3	0.1	-0.0	0.2	0.5	0.2	1.2	1.6	0.0	0.9	1.5	0.2	1.5	0.1
Leg fat-free mass (left)	0.4	2.0	8.6	-0.6	-1.7	-1.1	-0.2	-1.0	-1.1	-2.9	-1.1	-1.9	-0.9	-1.5	-1.5	-1.9	-1.7	-0.1	-1.7	-1.1	-0.4	-1.7	-1.4	-1.6	-0.3
Leg predicted mass (left)	0.4	2.1	9.3	-0.7	-1.8	-1.1	-0.2	-1.0	-1.1	-3.0	-1.1	-2.0	-0.9	-1.5	-1.6	-1.9	-1.7	-0.0	-1.7	-1.1	-0.4	-1.8	-1.5	-1.6	-0.3
Heart attack	0.4	0.5	3.2	-0.3	0.2	0.2	0.2	0.8	-1.8	0.5	0.5	-0.1	1.1	0.4	-0.4	0.7	0.6	1.1	0.8	0.6	0.7	-0.0	-0.9	0.6	0.5
Pain all over the body in last month	0.4	0.4	1.9	-0.5	0.5	0.6	0.6	0.7	-0.3	-0.0	0.8	0.1	0.5	0.8	0.0	0.7	0.7	0.6	0.7	1.1	1.4	-0.3	-0.7	0.5	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	3.5	-0.2	-0.2	0.1	1.7	0.6	-1.2	-0.7	0.2	-0.1	1.0	0.2	-0.2	-0.1	0.2	1.9	-0.2	-1.5	-0.4	-0.4	-1.4	-0.4	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	2.8	0.3	0.1	0.3	1.5	0.6	-0.4	0.5	0.5	0.4	1.4	0.1	0.5	0.1	0.4	1.4	0.2	-1.7	-0.1	0.3	-0.7	-0.6	0.4
Number of children fathered	0.4	0.5	2.2	-1.5	-0.5	-0.5	-0.5	-0.5	-0.2	-0.5	-0.2	-0.5	-0.3	-0.5	-0.5	-0.8	-1.0	-1.3	-0.4	-0.5	0.5	-1.1	-0.4	-0.8	-0.4
Medication: Allopurinol	0.4	0.6	3.4	0.5	0.4	0.6	-0.3	1.3	-0.7	0.2	0.7	-0.1	1.5	0.6	-0.4	0.5	0.7	1.8	0.2	0.5	0.6	0.1	-0.9	0.3	0.9
Medication: Aspirin	0.4	0.6	2.5	-0.4	0.1	0.5	-0.5	0.9	-1.6	0.6	0.4	-0.1	0.4	0.4	-0.5	0.5	0.6	1.6	0.7	0.4	0.6	-0.2	-1.4	0.7	0.8
Illnesses of siblings: Diabetes	0.4	0.5	2.3	0.0	-0.3	-0.3	0.4	-1.0	0.6	1.1	-0.3	0.7	-0.8	-0.9	0.8	0.1	-0.3	0.5	0.9	0.1	0.2	0.8	1.5	0.6	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	6.2	-0.1	-0.5	-0.4	-1.5	-0.8	-0.7	-0.2	-1.1	-0.4	-0.7	-0.6	-0.3	-0.3	-0.6	-2.5	-1.4	0.6	-1.1	-1.2	0.1	-0.8	-0.1
Average weekly champagne plus white wine intake	0.4	0.5	2.0	-1.3	0.4	-0.5	-1.4	-0.2	-1.0	0.2	-0.7	-0.6	-1.1	0.7	-0.7	0.1	0.2	0.4	0.7	0.5	0.2	0.0	0.4	0.9	-0.9
Medication: Blood pressure	0.4	0.7	5.1	-0.9	-0.6	-0.5	-1.2	-0.0	-2.1	-0.3	-0.5	-0.7	-0.3	-0.4	-1.0	-0.3	-0.4	2.3	0.4	-0.1	0.4	-0.6	-0.9	-0.0	-0.4
Medication: Atorvastatin	0.4	0.5	4.4	-1.2	-0.2	-0.3	0.3	-0.4	0.0	0.5	0.3	0.2	-0.4	-0.4	0.2	-0.2	-0.1	2.1	0.7	-1.6	0.5	0.3	0.2	-0.5	-0.6
Ever smoked	0.4	0.8	2.9	-1.5	-0.8	-1.2	-0.2	-0.8	-0.3	0.5	-0.5	-0.8	-0.8	-1.0	-0.7	-1.0	-0.9	1.4	0.0	-1.7	-0.6	0.3	0.3	0.1	-1.0
Bipolar Disorder (2018)	0.3	0.4	2.3	0.3	0.8	0.8	0.8	0.1	1.5	0.4	0.3	0.9	0.0	0.7	1.0	0.7	0.6	0.1	-0.1	-0.4	-0.2	0.7	1.2	-0.1	0.2
Schizophrenia (2018)	0.3	0.7	1.9	0.1	1.3	0.4	0.4	0.0	0.6	1.3	0.2	0.9	0.4	1.4	0.9	0.9	1.1	-1.0	1.1	0.1	0.5	1.2	1.0	0.8	-0.3
Schizophrenia vs Biploar Disorder	0.3	0.4	1.4	-1.0	-0.6	-1.0	-0.2	-0.4	-1.2	-0.6	-0.2	-0.7	0.0	-0.6	-0.6	-0.7	-0.9	-0.4	0.1	-0.7	0.0	-0.5	-0.5	-0.3	-0.6
Mean Putamen Volume	0.3	0.3	1.3	0.1	0.3	0.8	0.1	0.4	0.1	-0.3	0.8	0.1	-0.0	0.6	-0.0	0.4	0.6	0.6	-0.3	1.1	0.5	-0.7	-0.7	-0.3	0.9
Ulcerative Colitis	0.3	0.5	1.2	-0.4	-1.1	-0.9	-0.3	-0.5	-0.1	-0.9	-0.8	-0.9	0.3	-1.1	-1.1	-0.9	-0.9	-0.4	-0.4	-0.3	-0.1	-0.5	-0.3	0.3	-0.7
Blood Red Count	0.3	2.7	15.3	1.2	0.8	2.0	-2.2	1.6	-0.8	0.7	1.7	0.7	0.1	1.2	0.0	2.0	1.6	0.9	1.4	3.9	2.6	0.3	-1.5	1.4	1.9
Type 2 Diabetes (T2D) (2018)	0.3	0.5	3.9	-0.3	-0.3	-0.3	-1.1	0.0	-0.9	0.3	-0.5	-0.3	-0.3	-0.4	-0.3	-0.2	-0.0	2.0	1.1	0.7	0.6	0.4	0.2	1.0	-0.6
Frequency of depressed mood in last 2 weeks	0.3	0.4	5.8	-0.8	-0.0	-0.2	0.8	-0.2	0.3	-0.3	-0.3	-0.4	-0.0	0.1	-0.3	-0.4	0.0	2.4	-0.1	0.2	0.0	-0.1	0.0	0.2	-0.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.3	0.4	-0.1	0.4	0.7	0.7	-0.2	0.3	0.6	0.2	1.1	-0.1	0.0	0.4	0.0	0.8	1.1	0.9	1.1	0.6	-0.3	1.1	0.6
Supplements: Zinc	0.3	0.4	1.9	-1.1	0.2	-0.2	-0.0	-0.2	-0.6	-0.5	-0.3	-0.2	-0.9	0.1	-0.2	-0.1	-0.4	1.4	-0.1	-1.4	-0.2	-0.5	-0.4	-0.8	-0.3
Diabetes (father)	0.3	0.4	1.0	0.3	-0.3	-0.6	-0.5	-0.3	-1.0	0.9	-0.4	0.2	0.2	-0.6	0.2	0.1	-0.7	-1.0	1.0	0.3	0.5	0.6	0.7	0.7	-0.7
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.7	0.5	0.2	-0.1	0.1	0.0	0.2	0.2	-0.0	0.7	0.9	0.2	0.8	-0.1	0.5	0.5	1.3	-0.2	1.3	0.9	0.8	0.1	-0.5
Financial difficulties in last 2 years	0.3	0.4	1.5	-1.2	0.3	1.0	0.6	0.6	-0.3	-0.2	0.7	0.2	0.2	0.5	-0.1	0.6	0.7	1.0	0.3	0.8	0.6	-0.8	-1.0	0.7	0.5
Illnesses of siblings	0.3	0.4	1.4	0.4	0.9	0.1	0.6	0.2	1.2	0.6	0.2	0.5	0.4	0.9	0.7	0.5	0.4	-1.0	-0.1	-0.1	-0.6	0.8	1.1	0.5	-0.0
Pulse rate	0.3	0.5	1.8	-0.8	-0.8	-0.4	-1.4	-0.1	-0.9	-1.0	-0.2	-0.8	-0.8	-0.8	-1.0	-0.3	-0.5	0.1	0.4	1.0	0.6	-0.3	-0.4	0.6	-0.3
Medication: Cholesterol lowering	0.3	0.5	4.9	-1.0	-0.8	-0.2	-0.2	-0.1	-2.2	-0.1	-0.2	-0.4	-0.0	-0.7	-0.7	-0.2	-0.4	1.0	-0.0	-0.1	0.1	-1.1	-1.0	-0.6	0.1
Ever highly irritable/argumentative for 2 days	0.3	0.3	3.1	-0.6	0.1	-0.0	-0.2	-0.1	0.3	-1.8	-0.3	-0.4	-0.2	0.2	-0.2	-0.5	0.2	1.0	-0.3	0.4	0.6	-0.9	-0.5	-0.2	-0.3
Medication: Paracetamol	0.3	0.4	1.5	0.6	0.0	0.7	1.0	0.6	0.6	0.5	0.2	0.5	0.9	-0.1	0.3	0.6	0.2	1.2	0.4	-0.3	-0.4	0.8	-0.4	1.2	1.2
Worry too long after embarrassment	0.3	0.5	1.5	-0.9	-0.4	-0.7	1.0	-0.5	0.9	-1.2	-0.6	-0.6	-0.3	-0.3	-0.3	-0.8	-0.4	0.4	-0.6	-1.2	-0.7	-0.1	0.5	-0.1	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.9	-0.4	-0.0	-0.6	0.1	-0.4	-0.3	-0.0	-0.4	0.1	-0.5	-0.1	0.3	-0.4	-0.2	-0.1	-0.2	-1.4	-0.9	0.2	1.1	-0.7	-1.1
Age at first live birth	0.3	0.6	6.0	1.2	0.2	0.4	-1.4	0.1	0.1	-0.2	-0.2	0.3	0.0	0.3	0.2	0.3	0.3	-2.4	0.1	1.3	0.6	-0.2	-0.0	0.1	0.2
Health satisfaction	0.3	0.4	1.5	-0.3	0.3	0.6	0.6	0.7	-0.3	-1.0	0.7	0.0	0.5	0.4	-0.1	0.3	0.3	0.6	0.6	0.8	1.2	-0.3	-0.9	0.7	0.4
Alcohol intake frequency.	0.3	0.8	5.2	0.4	-0.3	-0.0	0.5	-0.8	2.3	0.0	-0.1	0.7	-0.7	-0.6	1.1	-0.5	-0.1	1.8	0.8	0.7	0.6	0.8	1.4	0.4	-0.8
Loneliness, isolation	0.3	0.4	6.6	-0.1	0.4	0.4	0.6	0.3	0.3	-0.1	0.4	0.1	-0.1	0.5	0.1	0.0	0.6	2.6	0.3	0.3	0.6	0.3	-0.0	0.5	0.2
Diabetes diagnosed by doctor	0.3	0.5	5.5	0.2	0.1	0.2	0.1	0.5	-0.3	0.5	0.3	0.3	0.1	-0.1	0.2	0.3	0.1	2.3	1.5	0.4	1.0	1.0	0.1	1.0	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.5	0.2	0.4	0.5	1.2	0.6	-0.2	0.5	0.4	0.7	1.2	0.4	0.6	0.7	0.6	0.8	0.7	-0.2	-0.0	0.8	0.1	0.9	0.4
Osteoporosis (self-reported)	0.3	0.3	2.3	-0.3	-0.5	-0.3	0.5	-0.7	0.6	0.0	-0.3	0.1	-1.2	-0.7	0.2	-0.3	-0.4	1.5	0.1	-0.0	-0.5	0.4	0.7	0.3	-0.3
Osteoarthritis (self-reported)	0.3	0.4	1.5	-1.2	-0.6	-0.9	-0.5	-0.2	-0.8	-0.6	-0.9	-1.1	0.3	-0.1	-1.1	-0.6	-0.2	-0.4	-0.0	-0.5	-0.3	-0.3	-0.2	0.5	-0.6
Age started oral contraceptive pill	0.3	0.3	4.8	0.3	-0.1	-0.2	0.3	-0.2	-0.1	-0.7	0.1	0.1	0.0	-0.2	0.2	-0.3	-0.5	-2.2	-0.6	0.0	-0.9	-0.4	-0.0	-0.3	0.1
Diastolic blood pressure, automated reading	0.3	1.0	4.2	-0.1	0.1	1.1	-0.4	0.3	-1.7	-1.4	1.0	0.2	-0.9	0.1	0.3	0.3	0.0	-1.4	-0.9	0.2	0.2	-1.8	-2.1	-1.6	1.2
Commuting to job workplace: Cycle	0.3	0.3	1.3	0.4	-0.6	-0.2	0.7	0.1	-0.6	-0.7	-0.2	-0.3	0.4	-0.7	-0.3	-0.1	-0.2	-0.4	-0.9	-1.1	-1.1	-0.3	-0.4	-0.6	0.2
Heart attack/myocardial infarction (self-reported)	0.3	0.4	4.0	-0.6	-0.1	-0.1	-0.2	0.5	-2.0	0.2	0.2	-0.4	0.9	0.1	-0.7	0.3	0.3	0.9	0.4	0.2	0.4	-0.4	-1.0	0.2	0.4
Alcohol drinker status: Previous	0.3	0.3	1.6	0.4	0.2	0.6	0.3	0.5	1.1	-0.0	0.7	0.4	0.4	0.2	0.4	0.1	0.4	1.3	0.6	0.7	0.8	0.4	-0.0	0.4	0.3
Depression (Nagel 2018)	0.2	0.4	3.2	-0.4	0.6	0.1	0.8	-0.2	0.8	0.3	-0.1	0.4	0.1	0.5	0.5	0.1	0.5	1.8	0.1	0.8	0.1	0.1	0.9	0.3	-0.4
Alzheimer’s Disease (including proxy)	0.2	0.3	1.6	0.2	-0.0	0.2	0.5	0.2	-0.1	-0.2	0.2	0.1	0.5	-0.1	0.2	-0.1	-0.5	-0.4	-0.9	-1.3	-1.2	-0.2	-0.4	-1.0	0.8
Smoking Status	0.2	0.4	2.3	-1.1	-0.4	-0.6	-0.4	-0.5	-0.0	0.4	-0.3	-0.3	-1.1	-0.5	-0.3	-0.5	-0.7	1.2	0.3	-1.5	-0.3	0.4	0.1	-0.2	-0.4
Relative age of first facial hair	0.2	0.5	2.7	0.6	0.1	-0.5	-0.3	-0.6	1.6	-0.0	-0.5	-0.1	-1.2	-0.1	0.1	-0.5	-0.1	1.4	-0.1	0.0	-0.4	0.8	1.2	0.2	-0.4
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.8	-0.1	0.6	0.3	-0.4	-0.1	0.4	0.9	0.4	0.6	-0.2	0.5	0.6	0.7	0.3	-0.6	0.2	0.2	0.1	0.3	0.7	-0.3	-0.1
Impedance of leg (right)	0.2	0.7	4.5	-1.2	-0.2	-0.9	-0.3	-0.8	0.6	1.0	-1.0	0.2	-0.6	-0.5	0.2	-0.1	-0.1	0.8	0.3	-0.5	-1.1	0.7	2.1	0.5	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	2.1	-0.8	0.1	0.2	0.9	-0.2	0.2	-0.4	-0.0	-0.1	-0.6	0.3	0.0	-0.1	0.3	1.5	-0.3	0.8	-0.1	-0.6	0.2	0.2	-0.2
Impedance of leg (left)	0.2	1.2	5.5	-1.7	-0.4	-1.2	-1.1	-1.1	0.6	0.7	-1.3	-0.2	-1.2	-0.7	-0.2	-0.3	-0.1	1.3	0.6	-0.1	-0.8	0.6	2.3	0.8	-2.2
Mouth/teeth dental problems	0.2	0.3	1.6	-0.2	0.1	0.1	-0.1	-0.2	-0.4	-0.4	-0.1	-0.3	-0.4	0.3	-0.2	-0.1	-0.1	-0.6	-1.1	-0.3	-0.5	-1.3	-0.6	-1.2	0.1
Allergy	0.2	0.5	1.6	-0.1	0.8	1.0	-0.1	1.1	-0.9	-0.1	0.6	0.1	1.0	1.1	-0.2	0.9	1.1	-0.5	0.1	0.2	0.4	-0.3	-1.2	0.1	1.3
Diabetes (self-reported)	0.2	0.3	1.6	0.1	-0.0	-0.1	-0.3	0.2	-0.8	0.4	0.0	0.1	0.1	-0.2	0.1	0.1	0.1	1.0	1.3	0.5	1.0	0.6	0.1	0.7	-0.2
Impedance of arm (right)	0.2	0.9	5.1	-1.3	-0.2	-1.5	-1.3	-0.5	0.6	0.7	-0.5	-0.3	-0.0	-0.3	-0.2	-0.6	-0.0	1.2	0.7	-1.1	-0.2	0.6	1.8	-0.2	-2.3
Hip circumference	0.2	0.7	4.8	0.7	0.3	0.6	-0.0	0.4	0.4	-0.8	0.6	-0.0	-0.4	0.4	0.1	0.0	0.4	1.9	1.1	1.2	2.2	0.3	-0.8	0.8	0.3
Time employed in main current job	0.2	0.2	1.0	0.2	0.3	0.1	-1.0	-0.0	0.6	0.7	-0.0	0.3	-0.5	0.2	0.1	0.4	0.6	-0.6	0.5	0.8	0.3	0.1	0.5	0.7	-0.5
Alcohol intake versus 10 years previously	0.2	0.3	1.6	-0.3	-0.6	-0.1	-0.8	0.3	-1.3	-0.4	-0.3	-0.5	0.5	-0.3	-0.9	0.0	0.1	0.5	0.2	0.2	0.0	-0.3	-0.7	0.3	-0.0
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.7	0.3	-0.4	-0.5	0.4	-0.7	0.4	-0.6	-0.2	-0.2	-0.3	-0.8	0.2	-0.8	-1.1	-1.3	-0.9	-0.2	-0.9	-0.4	0.2	-0.7	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.5	-0.7	-0.4	0.1	0.8	0.4	-0.4	-0.7	-0.0	-0.5	0.7	-0.1	-0.9	0.2	0.2	1.2	0.1	-0.1	0.1	-0.0	-0.7	0.8	0.1
Impedance of arm (left)	0.2	1.1	6.7	-1.5	-0.2	-1.6	-1.9	-0.6	0.6	0.7	-0.6	-0.5	-0.3	-0.3	-0.4	-0.7	-0.0	1.1	1.0	-0.8	0.2	0.7	1.9	0.1	-2.6
Headache pain in last month	0.2	0.3	1.7	0.4	0.1	-0.3	0.1	-0.4	0.8	0.5	-0.4	0.3	-0.1	-0.1	0.6	-0.4	0.1	1.3	0.8	-0.4	0.3	0.9	1.2	0.1	-0.8
Medication: Seretide 50 evohaler	0.2	0.3	0.9	0.7	0.3	0.2	-0.6	0.0	1.0	-0.2	0.1	0.5	-0.0	-0.0	0.7	0.1	0.4	0.9	0.6	0.4	0.6	0.7	0.3	0.8	-0.1
Heart disease (mother)	0.2	0.3	0.9	0.1	0.5	0.1	-0.4	-0.2	1.0	0.6	-0.1	0.7	-0.3	0.3	0.6	0.4	0.4	0.7	0.4	0.1	-0.2	0.7	0.9	0.2	-0.2
Pulse rate, automated reading	0.2	0.5	1.8	-0.5	0.1	-0.1	-1.3	-0.3	0.6	0.3	-0.2	0.1	-1.3	-0.1	0.0	0.0	0.2	0.7	1.4	0.6	1.1	1.0	0.9	1.0	-0.8
Suffer from ‘nerves’	0.2	0.3	1.2	-0.1	-0.6	0.0	1.0	-0.0	-0.6	-0.9	-0.2	-0.4	0.3	-0.6	-0.2	-0.3	-0.1	1.1	-0.2	-1.0	0.2	-0.3	-0.9	-0.6	0.3
Age at last live birth	0.2	0.3	4.7	0.4	0.3	0.2	-0.6	0.5	-0.3	-0.3	0.2	-0.1	0.5	0.4	-0.3	0.4	0.1	-2.2	-0.5	0.3	-0.2	-0.4	-0.4	-0.1	0.5
Illnesses of father: Heart disease	0.2	0.3	1.6	-0.8	-0.1	0.5	-0.9	0.4	-1.3	0.4	0.3	-0.0	0.4	-0.1	-0.4	0.6	0.0	0.1	0.2	0.2	0.4	-0.7	-1.0	-0.3	0.5
Medication: Gliclazide	0.2	0.2	1.3	0.4	-0.3	0.2	0.1	0.3	0.3	-0.3	0.5	0.1	0.1	-0.6	0.1	0.0	-0.4	0.7	0.4	1.2	0.6	0.2	-0.3	0.4	0.5
Hearing aid user	0.2	0.2	1.5	-0.6	-0.3	-0.5	0.4	-0.2	-1.2	-0.2	-0.4	-0.1	-0.2	-0.3	-0.0	-0.2	-0.6	-0.0	0.0	-1.0	-0.7	-0.3	-0.1	-0.3	-0.3
Mother’s age at death	0.2	0.3	1.4	-0.3	0.0	0.0	-0.9	0.4	0.4	0.5	0.2	-0.4	0.4	0.4	-0.6	0.1	0.8	-0.2	0.5	1.2	0.7	0.3	0.1	0.9	-0.1
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.5	0.7	-0.1	0.3	0.0	0.6	-0.1	-0.8	0.1	-0.3	0.4	-0.2	-0.4	0.1	0.1	-0.5	0.0	1.0	0.3	-0.0	-0.7	1.2	0.7
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.3	-0.4	-0.6	0.1	0.9	0.3	-0.6	-0.6	0.2	-0.5	0.3	-0.4	-0.7	0.0	0.1	1.1	0.0	-0.3	0.0	0.0	-1.1	0.7	0.7
Medication: Bendroflumethiazide	0.2	0.3	2.1	-0.3	-0.4	-0.7	-1.4	-0.2	-0.9	0.6	-0.4	-0.3	-0.3	-0.5	-0.4	-0.2	-0.6	-0.2	0.3	-1.1	-0.3	0.1	-0.0	-0.6	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.8	-0.8	0.2	0.1	-0.4	0.5	-0.8	0.5	0.2	-0.0	0.4	0.4	-0.2	0.2	0.7	1.4	0.7	-0.3	0.2	0.1	-0.2	0.5	-0.2
Pain experienced in last month	0.2	0.3	1.7	-0.0	-0.1	-0.1	-0.7	0.1	-0.7	-0.1	-0.1	-0.6	0.1	0.1	-0.6	-0.2	0.0	-0.7	-1.2	-0.7	-0.7	-0.9	-0.7	-1.3	0.2
Basal cell carcinoma (self-reported)	0.2	0.2	0.8	-0.0	0.2	0.6	0.0	0.5	0.2	-0.5	0.3	0.0	0.6	0.4	-0.0	0.2	0.5	0.0	-0.1	0.8	0.5	-0.4	-0.9	0.4	0.7
Impedance of whole body	0.2	1.2	6.8	-1.7	-0.4	-1.6	-1.8	-0.8	0.5	0.8	-1.0	-0.4	-0.6	-0.5	-0.3	-0.5	-0.1	1.4	0.9	-0.5	-0.3	0.7	2.2	0.4	-2.6
Fasting Glucose	0.1	0.1	0.9	-0.2	-0.0	0.1	0.1	0.1	0.9	-0.2	0.2	0.4	-0.1	0.3	0.3	-0.1	0.3	-0.5	-0.8	-0.2	-0.5	-0.4	0.1	-0.6	0.2
LDL Cholesterol	0.1	0.1	0.7	-0.5	0.1	0.2	0.2	-0.0	-0.6	0.1	0.1	0.1	-0.1	0.1	0.1	0.3	0.4	0.8	0.3	-0.0	0.1	-0.2	-0.2	0.1	-0.2
Schizophrenia (2014)	0.1	0.2	0.9	-0.9	0.5	-0.5	-0.1	-0.4	0.1	0.2	-0.5	-0.1	-0.3	0.5	-0.0	0.0	0.1	-0.6	0.3	-0.9	-0.1	0.4	0.7	0.3	-0.8
Hair Pigment	0.1	4.0	13.0	-0.5	-0.8	-2.6	-2.6	-3.0	1.3	0.6	-3.0	-0.4	-2.5	-1.6	0.6	-2.0	-2.1	-2.4	-0.7	-1.0	-1.5	0.0	3.6	-1.5	-3.4
Medication: Atenolol	0.1	0.1	2.0	-0.0	0.2	0.1	0.1	0.2	0.5	-0.4	0.3	0.1	-0.0	0.2	0.0	0.2	0.1	1.4	0.4	-0.2	0.2	0.4	-0.2	-0.1	0.4
Chronic bronchitis/emphysema (father)	0.1	0.1	0.8	0.3	-0.1	0.3	-0.7	-0.1	0.1	0.5	-0.5	0.2	-0.0	-0.1	0.1	0.2	0.4	0.2	-0.4	0.9	-0.4	-0.2	0.3	0.4	0.0
Hearing difficulty/problems with background noise	0.1	0.1	0.8	-0.2	0.4	-0.2	0.1	0.4	-0.9	0.2	0.0	-0.2	0.2	0.5	-0.3	0.2	0.1	0.3	0.2	-0.3	-0.1	0.4	-0.1	0.8	0.2
Weight	0.1	0.5	3.2	0.6	-0.1	0.2	0.6	0.0	0.1	-1.5	0.1	-0.3	-0.4	0.1	-0.0	-0.4	-0.1	1.8	0.5	0.4	1.4	0.1	-0.8	0.3	0.2
Hair/balding pattern: Pattern 4	0.1	0.2	1.2	-0.3	0.1	-0.1	-0.1	-0.1	-0.7	0.9	-0.3	0.1	0.4	0.0	0.0	0.3	-0.2	-1.1	0.1	-1.1	-0.6	0.2	0.0	-0.3	-0.0
Medication: Amlodipine	0.1	0.2	0.6	-0.6	-0.4	-0.0	0.1	0.2	-0.7	-0.5	0.3	-0.5	0.5	-0.3	-0.7	-0.2	-0.1	-0.0	-0.5	0.2	-0.4	-0.4	-0.8	0.1	0.7
Neck or shoulder pain in last month	0.1	0.2	0.7	-0.0	-0.2	-0.3	-0.6	0.2	-0.8	-0.3	-0.4	-0.2	0.4	-0.2	-0.5	0.2	-0.4	-0.5	0.6	0.4	0.1	0.3	-0.0	0.9	0.1
Medication: Paracetamol	0.1	0.2	1.3	0.3	-0.2	0.2	0.3	0.1	0.5	0.5	-0.1	0.3	0.4	-0.4	0.2	0.1	-0.1	1.1	0.1	-0.8	-0.6	0.6	-0.1	0.6	0.6
Heart disease (siblings)	0.1	0.1	0.4	0.1	-0.1	-0.0	0.5	-0.1	0.4	0.1	-0.1	0.2	0.6	-0.1	0.2	-0.0	0.2	-0.0	0.5	0.1	0.6	0.4	0.3	0.5	-0.1
Heel T-Score	0.0	0.4	1.8	-0.7	-0.4	-0.2	0.7	-0.3	-1.3	-0.6	-0.8	-0.5	-0.4	-0.1	-0.7	-0.0	-0.5	0.1	-0.8	0.3	-0.9	-0.9	-0.4	-0.1	0.4

Hub : Genes

ZNF585B

Models

Trait associations