Hub : Genes

DMWD

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1150	0.0380	3.7e-04	0.132	NA	0.151	NA	0.164	2.5e-07	NA	2.9e-08	NA	7.3e-09
2	GTEx	Artery Aorta	0.2800	0.0710	1.5e-06	0.189	NA	0.122	NA	0.150	1.1e-10	NA	3.0e-07	NA	1.2e-08
3	GTEx	Artery Tibial	0.2153	0.0467	7.3e-09	0.171	NA	0.161	NA	0.165	2.2e-13	NA	1.3e-12	NA	6.8e-13
4	GTEx	Brain Frontal Cortex BA9	0.2743	0.0978	5.3e-03	-0.007	NA	0.020	NA	0.021	5.6e-01	NA	9.8e-02	NA	9.0e-02
5	GTEx	Breast Mammary Tissue	0.1610	0.0630	7.7e-03	0.006	NA	0.025	NA	0.005	1.5e-01	NA	2.0e-02	NA	1.7e-01
6	GTEx	Breast Mammary Tissue (Male)	0.2948	0.1699	9.5e-02	-0.011	NA	0.027	NA	-0.011	6.9e-01	NA	8.0e-02	NA	6.7e-01
7	GTEx	Breast Mammary Tissue (Female)	0.0578	0.0681	2.5e-01	-0.003	NA	0.002	NA	0.049	4.0e-01	NA	2.8e-01	NA	1.4e-02
8	GTEx	Heart Left Ventricle	0.1567	0.0584	4.4e-03	0.015	NA	0.005	NA	0.019	5.3e-02	NA	1.7e-01	NA	3.3e-02
9	GTEx	Muscle Skeletal	0.0622	0.0232	1.5e-03	0.006	NA	0.010	NA	0.012	7.6e-02	NA	2.9e-02	NA	1.9e-02
10	GTEx	Nerve Tibial	0.2392	0.0519	2.3e-09	0.075	NA	0.048	NA	0.058	5.7e-06	NA	2.4e-04	NA	5.8e-05
11	GTEx	Skin Sun Exposed Lower leg	0.1020	0.0370	7.4e-04	0.071	NA	0.056	NA	0.065	1.6e-06	NA	2.1e-05	NA	4.1e-06
12	GTEx	Testis	0.1880	0.0610	3.4e-04	0.147	NA	0.097	NA	0.128	4.6e-07	NA	4.3e-05	NA	2.7e-06
13	GTEx	Thyroid	0.1070	0.0310	9.6e-06	0.116	NA	0.109	NA	0.112	3.4e-09	NA	1.1e-08	NA	6.7e-09
14	YFS	Blood	0.0553	0.0128	1.3e-13	0.041	0.047	0.047	0.047	0.044	2.2e-13	4.2e-15	3.8e-15	3.9e-15	2.7e-14
15	TCGA	Breast Invasive Carcinoma	0.0140	0.0099	6.5e-03	0.002	0.008	0.004	NA	0.005	1.4e-01	7.3e-03	4.5e-02	NA	2.2e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	0.5	0.8	9.0	0.3	0.2	0.2	3.0	-0.7	-0.8	0.0	0.3	0.3	-0.1	1.0	0.6	0.4	0.6	-0.2
Bipolar Disorder or Schizophrenia	0.5	1.3	5.4	-1.0	-0.9	-1.1	2.3	-0.1	-1.0	0.0	-2.1	-0.7	-1.4	-0.7	-0.7	-1.0	-0.7	0.6
Depressed Affect (Nagel 2018)	0.3	0.6	1.8	-0.7	-0.2	-0.4	-1.3	-0.8	-1.0	-0.8	-1.0	-0.4	0.0	-0.8	-0.8	-0.7	-0.5	0.6
Depression (Nagel 2018)	0.2	0.3	0.9	-0.2	-1.0	-1.0	-0.3	0.0	0.5	-0.4	-0.0	-0.9	0.3	0.5	0.6	-0.1	0.6	0.5
Intelligence (Savage-Jansen 2018)	0.4	1.4	9.7	0.0	-0.2	0.0	-3.1	-1.0	2.7	-0.1	-1.2	0.2	-0.4	0.1	0.3	0.1	0.4	-0.9
Neuroticism (Nagel 2018)	1.0	2.3	4.9	-1.7	-1.6	-1.8	-1.4	-1.3	-1.1	-1.1	-0.8	-1.9	-0.7	-1.6	-1.6	-1.7	-1.1	2.2
Schizophrenia (2018)	1.0	2.1	8.9	-1.6	-1.4	-1.5	0.9	0.3	-0.6	0.0	-3.0	-1.1	-1.8	-1.7	-1.4	-1.6	-1.4	1.0
Schizophrenia vs Biploar Disorder	0.4	0.6	2.3	0.8	0.5	0.4	0.6	1.5	-0.0	0.0	-0.4	0.8	0.5	0.7	0.8	0.8	1.3	-0.4
Worry (Nagel 2018)	1.3	2.6	5.3	-1.9	-2.0	-2.1	-1.4	-1.5	0.0	-0.7	-1.1	-2.1	-1.0	-1.5	-1.7	-1.9	-1.4	2.3
Alzheimer’s Disease (in mother)	0.5	0.5	2.5	0.6	0.3	0.3	-1.1	0.4	1.4	-0.4	1.6	0.0	0.5	0.8	0.6	0.6	0.4	-0.0
Alzheimer’s Disease (in father)	0.8	0.9	3.7	0.4	0.3	0.4	-0.4	-1.9	0.2	-1.4	1.4	0.1	1.1	1.2	0.6	0.5	1.1	0.1
Alzheimer’s Disease (including proxy)	4.2	6.1	18.8	2.8	2.1	2.1	0.0	-0.1	1.6	-1.0	4.3	1.6	3.3	3.4	3.0	2.8	3.1	-1.1
Crohns Disease (2017)	2.7	5.9	10.9	-3.2	-2.6	-3.0	-0.4	-0.6	0.1	-0.5	-2.3	-2.5	-3.2	-2.8	-2.6	-3.1	-3.3	1.9
Irritable Bowel Disease (IBD)	3.4	8.1	13.6	-3.6	-3.0	-3.4	-0.0	-1.8	0.6	-1.2	-3.0	-3.0	-3.3	-3.4	-3.2	-3.7	-3.6	2.3
Ulcerative Colitis (UC)	2.4	4.5	6.9	-2.5	-2.1	-2.2	0.2	-2.6	1.4	-2.0	-2.1	-2.3	-1.7	-2.5	-2.3	-2.6	-2.0	2.0
Major Depression (MDD)	0.6	0.7	3.6	-0.8	-0.5	-0.6	0.1	-0.8	-1.9	0.0	-0.3	-0.7	-0.9	-0.8	-0.7	-0.8	-0.5	1.2
Reaction Time	3.1	6.0	14.1	-2.9	-2.0	-2.2	0.6	-1.0	0.8	0.1	-3.0	-1.8	-3.4	-3.1	-3.2	-3.1	-3.8	2.0
Verbal and Numeric Reasoning (VNR)	0.6	1.4	7.4	-1.0	-1.0	-1.1	-2.7	-1.7	1.0	-0.7	-1.0	-0.8	-1.1	-1.0	-0.9	-1.0	-0.8	0.1
Breast Cancer	0.1	0.3	1.3	-0.3	-0.4	-0.3	0.8	0.5	1.1	-0.3	0.1	-0.7	0.2	0.4	-0.2	-0.3	-0.2	1.0
Ovarian Cancer	0.4	0.5	2.7	0.3	-0.4	-0.3	-0.0	-1.6	-0.9	-0.0	0.5	0.1	-0.1	1.1	0.9	0.5	0.9	-0.3
Prostate Cancer	0.3	0.5	1.9	0.6	0.3	0.8	-0.3	-0.2	1.1	-1.4	0.3	0.1	0.6	0.8	0.6	0.7	0.9	-0.2
Age at First Birth	1.6	2.3	5.4	-2.0	-1.6	-1.5	-0.5	-2.3	-0.3	-1.6	-1.2	-1.3	-1.7	-1.1	-1.6	-1.8	-1.3	1.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.1
Body Mass Index (BMI) (2010)	0.2	0.3	1.9	0.4	0.1	-0.0	0.4	-0.1	1.4	0.0	0.6	-0.1	0.5	0.7	0.7	0.5	0.6	-0.7
Coronary Artery Disease (CAD)	0.2	0.2	3.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.9
Crohns Disease (2012)	2.7	4.3	8.6	-2.5	-1.9	-2.4	-2.0	-0.8	0.6	0.0	-2.6	-1.8	-2.9	-2.3	-2.2	-2.5	-2.7	1.4
Mean Putamen Volume	0.7	0.8	4.0	0.7	1.3	1.3	0.5	2.0	-0.6	0.0	0.6	1.0	0.9	0.6	0.2	0.7	0.4	-0.2
Fasting Glucose	7.7	9.2	15.6	-4.0	-3.5	-3.8	-0.0	-0.1	0.5	0.6	-3.1	-3.6	-3.9	-3.4	-3.5	-3.9	-3.3	2.9
HbA1C	2.1	2.4	6.6	-1.3	-1.1	-1.1	0.2	-1.0	0.7	-0.2	-1.4	-1.1	-1.7	-2.0	-2.6	-2.3	-2.5	1.3
HDL Cholesterol	0.4	0.7	2.6	-0.8	-0.9	-0.9	0.4	0.6	0.2	0.0	1.1	-1.5	0.4	-0.2	-0.4	-0.7	0.5	1.6
LDL Cholesterol	0.4	0.6	3.2	0.4	-0.4	-0.3	-0.1	1.0	1.1	0.0	1.8	-1.1	0.2	0.4	0.5	0.5	0.9	0.6
Lupus	0.5	0.7	3.0	0.7	0.8	1.3	0.0	-1.7	0.4	-0.8	-0.0	1.1	1.0	0.5	0.5	0.8	0.2	-1.0
Neuroticism (2016)	4.3	6.3	14.8	-3.0	-3.6	-3.7	-0.3	-2.1	0.0	0.1	-1.1	-3.8	-2.1	-1.8	-2.2	-3.1	-1.1	3.8
Primary Biliary Cirrhosis	0.2	0.3	0.8	-0.2	-0.6	-0.7	0.9	0.8	-0.1	0.0	-0.2	-0.9	-0.3	0.3	0.3	-0.2	0.8	0.4
Rheumatoid Arthritis	1.0	1.4	8.8	-0.9	-0.6	-0.8	-1.2	0.3	1.6	0.0	-3.0	-0.3	-0.9	-1.1	-1.0	-1.0	-1.4	-0.3
Schizophrenia (2014)	0.8	1.7	5.5	-1.5	-1.2	-1.3	1.3	-0.0	-1.2	0.0	-2.4	-1.0	-1.8	-1.4	-1.3	-1.5	-0.7	1.2
Triglycerides	0.7	1.1	7.0	0.1	0.5	0.5	-0.1	-2.6	-0.5	0.0	-1.6	0.9	-0.5	-0.3	-0.4	-0.0	-1.4	-1.6
Type 2 Diabetes (T2D) (2012)	0.1	0.1	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5
Ulcerative Colitis	2.6	3.8	10.0	-2.2	-1.3	-1.4	0.0	-1.3	2.0	0.0	-3.2	-1.2	-1.5	-2.7	-2.7	-2.4	-2.9	1.0
Blood Eosinophil Count	5.2	40.3	121.0	-7.0	-11.0	-10.5	1.4	-5.3	3.4	-0.1	-1.2	-9.9	-7.7	-2.6	-2.6	-6.5	-0.8	8.3
Blood Platelet Count	4.3	50.3	89.1	9.4	7.9	7.6	-0.3	-0.2	-2.4	-0.8	5.7	8.2	8.4	8.5	8.6	9.4	8.4	-8.0
Blood Red Count	1.3	12.3	37.7	-4.1	-1.3	-1.5	-1.1	-0.4	0.2	-0.5	-3.8	-2.5	-3.4	-6.1	-5.4	-4.3	-5.9	3.0
Blood White Count	0.3	2.4	6.2	-1.6	-1.8	-2.0	-0.0	-1.1	-2.0	2.5	-1.2	-0.9	-2.1	-1.2	-1.1	-1.5	-1.9	0.8
Heel T-Score	1.9	15.3	26.6	4.6	3.9	4.5	2.3	4.2	4.5	-0.0	3.2	2.8	5.2	3.7	4.0	4.5	4.1	-4.1
BMI	0.4	2.1	7.3	-1.4	-0.9	-0.9	-1.1	1.4	2.7	2.0	0.1	-1.8	-0.2	-1.2	-1.4	-1.4	-1.9	0.9
Height	1.3	24.2	40.3	6.3	5.6	5.9	0.1	-0.9	0.2	-3.6	4.0	5.3	5.8	5.9	5.7	6.3	5.3	-5.4
Waist Hip Ratio (WHR)	3.7	16.4	26.3	-5.1	-4.8	-4.9	-1.1	-2.7	-2.0	-1.5	-2.9	-5.0	-4.9	-4.2	-4.3	-5.0	-4.2	4.7
Systolic Blood Pressure	4.7	23.7	53.4	6.0	6.9	7.3	-1.3	3.0	1.8	-1.0	1.5	6.9	6.0	3.4	4.0	5.8	2.1	-7.1
Smoking Status	0.3	0.7	4.6	0.4	1.0	0.6	-1.3	0.0	-2.1	-0.5	0.0	1.0	0.6	0.3	0.2	0.4	0.2	-0.6
Allergy or Eczema	0.3	0.7	1.4	1.1	0.6	1.0	0.8	-1.1	0.3	-0.4	0.4	1.2	1.0	0.5	0.8	1.0	0.3	-1.1
Cardiovascular Disease	0.2	0.6	2.9	0.1	0.2	0.6	-0.8	-0.2	0.3	-1.2	-0.2	0.4	0.9	-0.3	-0.1	0.2	-1.6	-1.7
Hypothyroidism (self reported)	0.2	0.5	2.7	0.6	1.2	1.0	1.6	0.1	0.5	-0.0	-0.1	0.8	0.5	0.5	0.1	0.5	0.4	-0.2
Respiratory disease	5.8	12.9	32.8	4.6	5.5	5.7	0.2	1.3	0.6	0.4	1.3	5.4	4.2	2.7	2.9	4.4	1.7	-4.6
Type 2 Diabetes (T2D) (2018)	4.5	8.4	19.0	-3.6	-2.9	-3.0	0.1	-2.6	1.1	-0.4	-2.9	-2.9	-3.5	-3.1	-3.1	-3.5	-4.4	2.6
Lung FEV1/FVC ratio	15.4	78.0	163.8	-11.5	-12.2	-12.5	0.1	-1.4	2.5	2.3	-4.7	-12.8	-10.2	-8.1	-8.5	-11.2	-6.3	11.2
Lung FVC	0.6	3.0	9.0	1.8	1.4	1.4	1.5	0.1	-1.6	-1.5	3.0	1.5	1.7	1.4	1.7	1.9	2.9	-0.1
Neuroticism	0.9	2.3	4.0	-1.9	-1.6	-1.8	-1.4	-1.0	-1.1	-0.4	-1.3	-1.6	-0.7	-1.4	-1.8	-1.9	-1.6	2.0
Chronotype (morning person)	0.8	1.8	4.5	1.6	1.3	1.1	-0.3	-1.1	-2.1	-0.3	1.5	1.4	1.2	1.2	1.6	1.7	1.8	-0.8
Hair Pigment	0.1	2.1	7.0	1.3	2.6	2.6	-0.5	0.1	-0.7	-0.6	0.7	2.3	2.1	0.2	-0.0	1.0	-0.5	-1.7
Tanning	0.1	1.1	3.9	-1.1	0.1	0.1	-1.1	-0.2	0.1	-0.4	-0.4	-0.4	-0.6	-1.9	-2.0	-1.2	-1.7	1.1
Hand grip strength (left)	1.4	3.6	13.5	2.0	0.8	0.8	0.6	1.0	1.6	-1.4	3.7	0.2	2.0	2.5	2.6	2.1	2.8	-0.6
Number of treatments/medications taken	0.3	0.5	2.7	0.3	0.1	0.2	-1.4	1.6	1.1	0.3	0.5	-0.2	0.4	0.4	0.3	0.3	0.3	-0.1
Average weekly spirits intake	0.6	0.7	4.4	-0.8	-0.9	-0.6	-2.1	-0.2	0.6	0.1	-0.3	-0.5	-1.0	-0.8	-0.9	-0.8	-0.7	0.7
Sensitivity / hurt feelings	0.3	0.5	1.2	-0.8	-0.6	-0.7	-0.2	0.8	-0.4	0.9	-0.6	-0.8	-0.0	-0.2	-0.9	-0.8	-0.3	1.1
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.1	0.5	-0.3	-0.3	-0.4	0.1	-0.5	0.7	0.0	-0.1	0.9	1.0	1.1	0.6	0.7	-0.1
Hearing difficulty/problems: Yes	1.6	2.4	8.2	-1.4	-0.3	-0.4	-2.6	0.1	0.2	-0.7	-1.8	-0.6	-1.1	-2.6	-2.0	-1.5	-2.9	0.3
Relative age of first facial hair	5.4	11.0	19.4	-4.4	-3.5	-3.5	-0.4	-0.3	-1.0	2.8	-3.7	-3.1	-4.1	-3.9	-4.2	-4.4	-3.2	3.3
Other serious medical condition/disability diagnosed by doctor	3.4	4.4	7.2	-2.7	-2.5	-2.5	-1.2	-0.2	-0.4	0.7	-1.2	-2.6	-2.4	-2.4	-2.4	-2.7	-2.5	2.3
Ever used hormone-replacement therapy (HRT)	0.8	1.1	4.1	0.9	1.3	1.4	0.1	0.8	-2.0	-0.0	-0.1	1.7	1.0	0.1	0.2	0.9	0.2	-1.5
Ever had hysterectomy (womb removed)	0.8	1.0	3.0	0.8	1.3	1.3	-1.7	0.6	-1.1	1.1	-0.1	1.1	1.1	0.5	0.2	0.8	0.0	-1.1
Systolic blood pressure, automated reading	3.6	10.4	23.2	4.0	4.7	4.7	-0.8	2.6	0.6	-0.7	1.2	4.5	3.9	2.2	2.6	3.8	1.2	-4.8
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	2.2	-0.6	-0.1	-0.1	-0.6	-1.2	0.2	-0.6	-1.5	-0.0	-0.8	-0.9	-0.7	-0.7	-1.4	-0.2
Angina	4.7	6.1	10.9	-3.0	-2.8	-2.9	-2.3	-1.7	-0.8	-0.9	-0.4	-3.3	-2.8	-2.4	-2.7	-3.0	-2.4	3.2
Medication for hormone replacement therapy	0.3	0.4	2.2	0.4	0.4	0.4	-0.4	0.3	-1.5	1.3	-0.5	0.6	0.0	-0.3	0.0	0.3	0.1	-0.3
Vitamin and mineral supplements	3.6	4.8	10.9	-2.9	-3.1	-3.0	-1.3	-0.3	0.1	0.2	-0.3	-3.3	-2.5	-1.8	-2.1	-2.8	-1.3	3.1
Supplements: Zinc	0.2	0.2	0.8	-0.0	-0.2	-0.1	0.6	0.8	0.9	0.6	-0.5	-0.3	0.6	0.0	0.1	-0.0	0.3	0.4
Medication: Co-codamol	0.4	0.5	1.4	0.7	0.7	0.8	0.3	0.9	-1.2	1.0	0.8	0.6	0.6	0.7	0.4	0.7	0.5	-0.3
Medication: Metformin	2.0	2.9	6.3	-2.0	-1.8	-1.8	-0.1	-1.8	0.4	-0.3	-1.1	-1.7	-2.3	-2.1	-1.6	-2.0	-2.5	1.5
Diabetes (father)	6.1	7.5	15.3	-3.2	-2.4	-2.4	0.1	-2.1	0.7	-0.6	-3.8	-2.1	-3.6	-3.5	-3.4	-3.3	-3.9	2.0
Diabetes (mother)	4.6	5.8	13.3	-3.0	-3.6	-3.3	-0.1	-2.0	1.0	0.5	-2.3	-3.0	-2.9	-2.0	-2.1	-2.9	-2.5	1.9
Severe depression (siblings)	0.2	0.2	1.2	0.1	0.3	0.7	-0.1	0.4	1.1	-0.6	0.3	0.5	0.3	-0.0	-0.4	0.0	-0.3	-0.2
Pack years adult smoking proportion	1.5	2.3	7.3	-1.8	-1.1	-1.0	-0.6	-2.0	-0.7	-0.7	-1.0	-0.9	-1.9	-1.9	-2.1	-1.8	-2.7	0.7
Impedance of leg (right)	0.5	2.5	5.8	1.7	1.6	1.7	0.2	-1.0	-2.4	-1.0	-0.6	2.4	1.5	1.2	1.2	1.6	1.3	-2.3
Leg fat-free mass (left)	0.8	4.0	7.9	2.2	2.3	2.4	-0.4	1.7	2.8	1.0	2.3	1.3	2.6	2.1	2.0	2.3	1.5	-1.6
Trunk fat percentage	0.4	1.6	5.3	0.6	1.4	1.1	-1.4	2.2	1.3	2.3	-0.9	0.9	0.9	0.3	0.0	0.5	-0.9	-1.6
Hand grip strength (right)	2.0	5.5	19.6	2.4	1.2	1.3	1.0	0.6	2.5	-2.0	4.4	0.4	2.4	3.2	3.0	2.5	3.4	-0.5
Townsend deprivation index at recruitment	0.4	0.5	5.8	-0.2	-0.5	-0.5	-0.1	1.0	-2.4	0.3	-0.2	-0.2	-0.2	0.5	0.3	-0.1	0.2	-0.2
Current tobacco smoking	0.7	1.1	5.3	-0.9	-0.1	-0.2	-1.8	-0.5	-2.3	0.3	-0.9	0.3	-0.9	-0.9	-1.2	-0.9	-1.4	-0.2
Average weekly fortified wine intake	0.9	1.1	1.8	1.1	1.2	1.2	1.4	1.0	0.6	1.2	0.9	1.0	1.2	0.5	1.0	1.1	0.5	-1.1
Maternal smoking around birth	0.6	0.9	11.2	0.0	-0.1	-0.2	-1.4	0.1	-3.4	-0.3	-0.2	0.1	-0.4	0.3	0.2	0.1	-0.1	-0.5
Fed-up feelings	0.7	1.3	2.6	-1.4	-1.2	-1.2	-1.6	-0.2	-1.1	0.2	-1.1	-1.4	-0.9	-1.0	-1.1	-1.3	-0.7	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.0	0.0	-0.9	-0.9	-1.0	-0.1	0.4	-0.2	-0.6	-0.6	0.2	0.8	0.8	0.2	0.6	0.3
Relative age voice broke	7.2	10.9	18.4	-4.2	-3.3	-3.4	-0.0	0.3	-1.0	2.8	-3.9	-3.0	-4.3	-4.2	-4.0	-4.2	-3.8	2.5
Taking other prescription medications	0.1	0.2	0.7	0.3	0.1	-0.1	-0.6	0.7	0.2	-0.3	0.9	-0.2	0.3	0.4	0.4	0.3	0.6	0.6
Age when periods started (menarche)	0.3	0.8	1.8	-0.9	-0.3	-0.3	-0.2	-0.3	-1.3	1.3	-0.6	-0.2	-1.0	-1.4	-1.1	-0.9	-1.3	0.2
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	3.0	1.0	0.7	0.7	-1.2	0.9	-0.2	0.9	1.7	0.3	1.2	0.8	0.9	1.0	1.2	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	8.9	1.0	1.5	1.5	1.1	1.8	3.0	-0.5	-0.8	0.9	1.7	-0.2	0.4	0.9	0.3	-1.6
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	3.5	1.5	1.8	1.9	-0.2	1.6	0.8	0.5	-0.2	1.7	1.6	0.9	1.0	1.4	0.9	-1.6
Qualifications: CSEs or equivalent	0.6	0.8	4.2	-0.3	-0.5	-0.4	0.6	1.4	0.8	2.0	-1.6	-0.2	-0.3	0.2	-0.2	-0.3	-0.8	-0.2
Serious illness, injury or assault to yourself	1.8	2.2	4.7	-2.0	-1.3	-1.3	-0.9	0.4	0.3	0.6	-0.9	-1.6	-1.2	-1.8	-2.2	-2.0	-1.9	1.9
High blood pressure	0.3	0.9	4.6	0.5	1.0	1.2	-1.2	0.2	0.1	-0.9	-0.4	1.0	0.7	-0.2	-0.2	0.4	-1.5	-2.1
Hayfever, allergic rhinitis or eczema	0.4	0.8	2.0	1.1	0.5	0.7	0.2	-1.2	0.8	0.4	0.1	1.1	0.6	0.8	1.1	1.1	0.5	-1.4
Multivitamins +/- minerals	1.6	2.1	4.0	1.9	1.8	1.9	1.5	0.5	-0.7	0.3	0.4	2.0	1.3	1.3	1.5	1.8	1.1	-1.9
Stomach or abdominal pain in last month	0.7	0.8	5.2	-0.2	0.2	0.3	2.2	-0.7	-2.3	0.8	-0.4	-0.2	-0.0	-0.2	-0.5	-0.2	-0.6	0.4
Supplements: Glucosamine	0.9	1.2	3.6	1.2	1.9	1.9	1.3	0.1	-0.5	1.0	0.5	1.7	1.1	-0.0	0.2	1.0	0.1	-1.0
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	1.6	-1.2	-0.9	-1.0	0.7	0.4	0.5	0.3	-0.3	-1.0	-1.1	-0.8	-1.3	-1.2	-1.0	1.2
Medication: Atenolol	1.4	1.8	4.2	-1.5	-0.9	-0.9	-0.9	-1.0	-0.9	-0.2	-1.1	-1.1	-1.7	-2.0	-1.8	-1.6	-1.9	1.0
Medication: Levothyroxine sodium	0.3	0.6	1.1	0.9	1.1	0.8	0.7	1.1	0.4	0.3	-0.2	1.0	0.5	0.8	0.7	0.8	1.0	-0.7
Sitting height	5.0	35.2	59.4	7.7	7.3	7.7	1.3	-0.4	0.3	-2.9	5.0	7.0	7.1	6.4	6.7	7.7	5.7	-6.7
Chronic bronchitis/emphysema (father)	0.3	0.4	1.7	0.2	-0.1	-0.2	-0.3	1.3	1.3	0.8	-0.1	-0.0	0.1	0.6	0.7	0.4	0.6	-0.2
High blood pressure (mother)	1.7	2.3	8.6	1.6	2.2	2.3	0.7	-0.5	0.6	-0.3	-1.1	2.3	1.7	0.5	0.7	1.6	-0.1	-2.9
Body mass index (BMI)	0.4	1.6	4.8	-1.0	-0.2	-0.5	-1.0	2.1	2.2	2.2	-0.7	-1.1	-0.2	-1.1	-1.2	-1.0	-1.7	0.3
Impedance of leg (left)	0.6	3.0	5.9	2.0	1.6	1.7	-0.3	-1.3	-2.4	-1.4	-0.1	2.4	1.5	1.7	1.7	1.9	1.8	-2.3
Leg predicted mass (left)	0.7	3.9	7.5	2.2	2.3	2.4	-0.4	1.7	2.7	1.1	2.2	1.3	2.5	2.1	1.9	2.2	1.4	-1.6
Trunk fat mass	0.6	2.4	4.9	1.3	2.0	1.8	-1.4	2.2	2.1	1.8	-0.0	1.3	1.7	1.0	0.8	1.3	-0.1	-2.1
Waist circumference	0.1	0.3	1.8	-0.5	-0.2	-0.4	-1.3	0.3	0.7	0.7	-0.2	-0.7	-0.0	-0.1	-0.4	-0.4	-0.9	-0.0
Number of incorrect matches in round	0.6	0.9	2.1	-1.2	-1.4	-1.3	-0.4	0.0	-1.2	-0.3	-0.3	-1.0	-1.0	-0.8	-0.9	-1.2	-0.7	1.1
Past tobacco smoking	0.3	0.6	2.4	-0.8	-0.6	-0.1	1.0	-0.6	0.3	0.6	-0.4	-0.4	-0.9	-1.2	-1.0	-0.8	-1.6	0.3
Alcohol usually taken with meals	0.8	1.4	2.7	1.6	1.4	1.3	-0.2	-1.2	0.1	-0.6	0.3	1.4	0.8	1.2	1.4	1.6	1.0	-1.5
Nervous feelings	1.6	3.0	5.6	-2.3	-2.4	-2.2	0.3	-1.6	-0.7	-0.6	-1.4	-2.2	-1.5	-1.6	-1.9	-2.2	-1.2	2.2
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.9	5.5	-2.1	-2.2	-2.3	-0.6	-1.0	-1.5	-0.1	-1.6	-2.0	-1.8	-1.5	-1.6	-2.1	-1.6	1.9
Hearing difficulty/problems with background noise	0.1	0.2	0.6	-0.1	0.3	0.2	-0.3	-0.6	-0.5	-0.6	-0.2	0.1	-0.1	-0.7	-0.5	-0.2	-0.7	0.3
Hair/balding pattern: Pattern 2	0.8	1.0	2.4	1.1	1.4	1.3	-1.6	-0.1	-1.0	-0.7	1.0	1.1	1.1	-0.1	0.6	1.0	1.0	-0.8
Had menopause	0.3	0.4	3.2	0.4	0.2	0.3	0.3	0.8	-1.8	0.5	-0.1	0.6	0.1	0.3	0.4	0.4	0.3	-1.0
Had other major operations	1.4	1.7	8.1	-0.3	-0.5	-0.2	2.9	0.6	-2.5	1.8	2.1	-0.5	-0.3	-0.3	-0.2	-0.2	0.1	1.6
Forced vital capacity (FVC)	3.2	12.3	22.5	4.3	3.8	4.1	2.2	-0.3	-0.7	-2.2	4.7	3.4	4.6	3.6	3.7	4.3	4.4	-2.0
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	6.7	1.7	2.2	2.3	1.0	1.6	2.6	-0.2	-0.2	1.8	2.5	0.2	0.8	1.5	0.4	-2.2
Ever unenthusiastic/disinterested for a whole week	1.6	1.9	3.6	-1.6	-1.4	-1.3	-1.9	-1.7	0.6	-1.4	-0.8	-1.7	-0.8	-1.2	-1.3	-1.6	-0.8	1.9
Qualifications: None of the above	0.8	1.7	11.7	-1.2	-0.6	-0.7	-0.8	0.9	-3.4	-0.0	-0.1	-0.9	-0.9	-1.2	-1.6	-1.3	-0.9	1.2
Financial difficulties in last 2 years	0.8	1.1	6.3	-0.9	-0.5	-0.6	-0.5	-1.4	-2.5	-0.5	-0.0	-0.6	-1.0	-0.7	-1.0	-0.8	-0.6	1.4
Mouth/teeth dental problems	0.8	1.3	2.9	1.5	1.0	0.8	0.2	0.6	-0.1	0.6	1.4	1.1	1.0	1.3	1.7	1.6	1.2	-1.1
Heart attack	2.4	3.1	5.1	-2.0	-2.0	-2.1	-1.2	-2.1	0.3	-1.6	-0.4	-2.3	-2.2	-1.5	-1.7	-2.0	-1.4	2.0
Allergy	1.5	3.4	7.6	-2.4	-2.1	-2.5	0.2	0.6	-0.7	-0.9	-0.8	-2.8	-1.9	-1.8	-1.9	-2.4	-1.2	2.7
Pain all over the body in last month	2.9	3.1	7.3	-2.2	-2.4	-2.5	-0.6	1.1	-0.6	1.4	0.6	-2.7	-2.1	-1.1	-1.4	-2.1	-0.6	2.6
Diabetes (self-reported)	2.0	3.1	8.2	-2.0	-1.4	-1.7	-0.9	-2.0	-0.7	-0.7	-1.4	-1.3	-2.2	-2.0	-1.9	-2.0	-2.9	1.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.5	0.6	1.0	1.2	0.6	-1.2	-0.3	-0.4	-0.6	1.1	0.3	0.2	0.0	0.5	-0.5	-0.7
Medication: Ramipril	0.5	0.7	2.1	-0.1	-1.1	-0.9	0.8	0.2	1.5	0.3	0.8	-1.2	0.0	0.9	0.8	-0.0	0.8	1.0
Medication: Simvastatin	8.0	11.8	20.3	-4.5	-4.2	-4.0	1.5	-0.9	0.5	0.2	-1.5	-4.5	-3.8	-4.0	-3.9	-4.4	-3.6	4.4
Fluid intelligence score	0.3	0.7	2.3	-0.7	-0.8	-0.8	-1.0	-1.5	1.1	-0.6	-0.9	-0.4	-0.8	-0.8	-0.6	-0.7	-0.5	-0.1
Illnesses of siblings	1.2	1.7	4.0	1.3	1.8	1.8	0.8	1.5	0.9	0.7	1.7	1.4	2.0	0.5	0.7	1.2	1.2	-0.3
Neuroticism score	0.8	1.7	3.5	-1.7	-1.6	-1.8	-1.2	-1.0	-0.5	-0.5	-1.1	-1.7	-0.6	-0.9	-1.3	-1.6	-0.8	1.9
Weight	0.7	3.5	7.0	2.1	2.5	2.4	-0.8	1.7	2.4	0.7	1.3	1.5	2.6	1.7	1.6	2.1	0.8	-2.3
Impedance of arm (right)	0.2	1.0	6.0	0.8	0.5	0.7	0.0	-1.2	-2.5	-0.4	-0.3	1.4	0.3	1.1	0.8	0.8	0.9	-0.9
Arm fat percentage (right)	0.4	1.4	7.3	-0.4	0.3	0.1	-1.2	2.1	1.9	2.7	-1.2	-0.2	0.0	-0.5	-0.6	-0.4	-1.3	-0.6
Trunk fat-free mass	1.0	5.9	10.8	3.0	2.9	3.0	-0.1	0.6	2.5	-0.7	2.5	2.0	3.3	2.5	2.7	3.1	2.2	-2.4
Hip circumference	1.4	6.2	11.0	3.1	3.3	3.1	-0.6	1.7	1.3	1.2	1.3	2.8	3.3	2.5	2.5	3.0	1.9	-3.2
Time employed in main current job	0.5	0.6	3.4	-0.7	-0.7	-0.6	0.5	-1.4	0.3	-1.8	-0.2	-0.6	-0.6	-0.3	-0.5	-0.6	-0.7	0.2
Alcohol intake versus 10 years previously	2.1	3.1	14.8	-1.8	-1.0	-1.1	0.1	0.4	3.9	-0.2	-2.7	-1.2	-1.1	-1.8	-2.0	-1.8	-2.0	1.1
Father’s age at death	1.8	2.4	5.7	1.9	2.3	2.3	0.6	0.2	2.1	-0.5	0.3	2.4	1.4	0.6	1.0	1.7	0.5	-2.0
Worrier / anxious feelings	0.5	0.9	2.5	-0.7	-1.5	-1.6	0.2	-1.4	-0.7	-0.1	0.4	-1.4	-0.1	0.6	0.0	-0.6	0.7	1.5
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.4	4.1	-1.3	-1.2	-1.3	-0.5	0.4	-0.6	1.2	-2.0	-1.1	-1.2	-1.2	-1.0	-1.2	-1.5	0.7
Falls in the last year	1.6	2.2	3.5	-1.9	-1.6	-1.5	-1.1	-1.6	-0.8	-0.5	-1.9	-1.3	-1.6	-1.2	-1.6	-1.8	-1.8	1.2
Hair/balding pattern: Pattern 3	0.1	0.2	0.9	0.0	-0.1	-0.2	-1.0	-0.4	-0.4	-0.2	-0.7	-0.1	-0.2	0.5	0.1	0.1	-0.4	-0.6
Number of live births	0.4	0.6	3.1	-0.5	-0.3	-0.2	0.8	1.1	-1.8	1.4	-0.3	0.0	-0.7	-0.4	-0.6	-0.5	-0.2	0.1
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	8.7	0.6	-0.1	0.1	2.5	-0.9	-0.1	-1.5	2.9	-0.6	1.2	0.9	1.0	0.7	2.3	1.5
Pulse rate	0.4	0.6	2.9	-0.6	-1.2	-1.1	0.3	-0.3	0.8	1.7	-0.2	-1.0	-0.7	0.1	0.0	-0.5	-0.4	0.7
Happiness	0.6	0.8	2.5	-1.0	-1.6	-1.6	-0.7	-0.6	-0.3	0.1	0.0	-1.4	-0.6	-0.2	-0.2	-0.9	0.1	1.2
Noisy workplace	1.2	1.5	4.6	-1.4	-0.3	-0.3	-0.7	0.5	0.5	-0.2	-1.9	-0.4	-0.8	-2.0	-2.0	-1.5	-2.2	0.4
Qualifications: A levels/AS levels or equivalent	1.0	2.2	4.0	1.7	1.1	1.0	0.3	-1.5	1.6	-1.0	1.9	0.9	1.7	1.7	2.0	1.8	1.9	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.8	-0.2	-0.1	0.2	0.2	-0.5	1.4	0.8	-1.7	0.5	-0.5	0.0	-0.3	-0.1	-0.4	-0.8
Mouth/teeth dental problems: Dentures	0.9	1.5	3.2	-1.5	-0.8	-0.8	0.3	-0.9	-0.5	-0.2	-1.8	-0.6	-1.6	-1.7	-1.8	-1.6	-1.5	0.6
Asthma	6.8	13.5	34.2	4.6	5.6	5.8	-0.1	1.5	-0.7	1.5	1.0	5.8	4.0	2.6	2.7	4.4	1.5	-4.9
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.9	-0.4	-0.3	-0.2	-1.4	0.4	-0.4	0.6	-0.8	-0.4	-0.4	-0.4	-0.5	-0.3	-0.5	0.2
Medication: Cholesterol lowering	2.4	3.7	8.3	-2.3	-2.6	-2.5	0.2	-1.0	2.2	-1.2	-0.1	-2.9	-1.7	-1.5	-1.7	-2.2	-1.6	2.5
Depression (self-reported)	0.7	0.9	1.7	-1.1	-1.1	-0.9	0.7	-0.8	-0.9	0.7	-0.8	-0.8	-0.7	-1.3	-1.1	-1.1	-1.0	0.8
Medication: Lansoprazole	2.2	2.5	9.4	-1.1	-2.0	-2.0	1.4	1.7	-1.3	3.1	0.7	-2.1	-0.9	0.3	-0.1	-1.0	0.8	2.1
Prospective memory result	0.7	0.8	2.7	0.8	1.4	1.5	-0.2	0.0	-0.4	-1.6	0.5	0.9	1.4	0.4	0.1	0.8	0.0	-0.7
Lung cancer (father)	0.8	1.0	4.5	-0.7	-0.2	-0.0	-0.2	2.1	-0.5	2.1	-0.2	-0.3	-0.9	-0.9	-1.2	-0.8	-1.0	0.1
Illnesses of mother	0.3	0.3	1.1	-0.6	-1.0	-1.0	0.2	0.4	0.1	0.1	0.0	-0.7	-0.8	-0.1	-0.0	-0.6	0.4	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	8.2	0.5	-0.1	0.1	2.9	-0.6	-0.1	-1.0	2.6	-0.6	0.9	0.8	0.8	0.5	2.1	1.5
Pulse wave Arterial Stiffness index	0.4	0.5	1.3	0.0	-1.0	-1.1	-0.6	-0.1	0.2	0.1	0.6	-0.9	-0.0	1.0	1.0	0.2	1.2	0.1
Impedance of arm (left)	0.2	1.2	6.4	0.9	0.7	0.9	-0.1	-1.1	-2.5	-0.4	-0.4	1.6	0.3	1.1	0.8	0.9	0.7	-1.1
Arm fat mass (right)	0.3	1.4	4.8	0.5	1.2	1.0	-1.1	2.1	2.2	1.9	-0.4	0.4	1.0	0.3	0.2	0.5	-0.7	-1.3
Trunk predicted mass	1.0	5.8	10.4	3.0	2.9	3.0	-0.1	0.7	2.4	-0.7	2.6	2.0	3.2	2.5	2.7	3.1	2.3	-2.3
Standing height	2.8	27.4	47.3	6.8	6.0	6.3	0.0	-0.4	0.5	-2.7	4.5	5.8	6.4	6.2	6.2	6.9	5.5	-5.7
Length of working week for main job	0.3	0.3	0.7	0.5	-0.1	0.1	0.4	-0.9	-0.2	-0.2	-0.3	0.6	0.3	0.8	0.7	0.5	0.8	-0.7
Exposure to tobacco smoke at home	1.3	1.4	11.0	-0.4	0.3	0.5	0.3	0.8	3.3	0.2	-2.3	0.6	0.4	-1.0	-0.8	-0.4	-1.2	-0.5
Breastfed as a baby	0.9	1.2	2.5	-1.2	-1.1	-0.9	-1.6	-1.5	0.9	-0.5	-1.1	-0.8	-1.2	-0.9	-1.1	-1.3	-0.9	0.7
Tense / ‘highly strung’	1.2	2.0	3.9	-1.5	-1.7	-1.8	0.3	-2.0	-1.1	-1.7	-1.1	-1.6	-1.2	-1.0	-1.1	-1.5	-1.2	1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.2	3.8	-1.9	-1.6	-1.4	-1.3	-1.8	-0.6	-0.4	-1.1	-1.3	-1.3	-1.6	-1.7	-1.9	-1.3	1.9
Hair/balding pattern: Pattern 4	0.4	1.1	4.0	-0.1	-1.0	-1.0	2.0	1.0	0.6	0.8	1.4	-1.3	0.0	0.6	0.7	0.0	1.3	1.4
Birth weight of first child	0.4	0.8	4.8	0.2	-0.3	-0.2	0.2	-0.6	0.5	-0.4	2.2	-0.6	0.7	0.9	0.6	0.3	1.4	1.3
Peak expiratory flow (PEF)	0.8	1.9	5.8	1.1	0.4	0.5	2.3	-0.9	-0.8	-0.5	2.4	0.0	1.5	1.5	1.6	1.1	2.4	0.2
Pulse wave reflection index	0.8	1.0	2.5	-0.6	-1.5	-1.5	-0.3	0.8	1.5	-0.1	0.9	-1.6	-0.4	0.4	0.3	-0.5	1.1	1.1
Ever highly irritable/argumentative for 2 days	2.3	2.8	8.4	-1.9	-1.7	-1.9	-2.9	-0.3	1.0	-0.6	-1.7	-1.7	-2.1	-1.1	-1.6	-1.8	-1.3	1.9
Loud music exposure frequency	1.0	1.1	1.9	-1.4	-1.0	-1.0	-0.5	0.8	-0.2	1.3	-1.0	-1.0	-1.2	-1.3	-1.3	-1.4	-0.7	0.9
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	9.6	-0.2	-0.4	-0.5	-1.1	-2.2	3.1	-2.1	-0.1	-0.7	0.0	-0.2	0.2	-0.1	0.7	0.8
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	4.3	-1.4	-0.8	-0.6	-1.1	-0.5	1.1	-0.2	-2.1	-0.6	-1.2	-1.5	-1.8	-1.5	-1.7	0.5
Blood clot in the leg (DVT)	3.1	4.1	7.7	-2.6	-2.6	-2.4	-0.7	-1.5	0.0	-0.1	-0.2	-2.8	-2.3	-2.0	-2.2	-2.6	-1.5	2.7
Medication: Paracetamol	0.9	1.5	6.7	0.4	1.4	1.2	-1.5	2.6	0.1	2.6	-1.0	0.7	0.7	-0.3	-0.6	0.3	-0.2	-0.2
Headache pain in last month	6.6	11.3	20.5	4.2	4.5	4.5	0.0	2.3	-1.6	0.5	1.4	4.4	4.3	3.4	3.1	4.2	2.3	-4.3
Medication for cholesterol, blood pressure or diabetes	0.9	1.4	4.3	1.3	1.6	1.4	-0.5	-0.0	-2.1	1.3	0.1	1.7	0.9	0.7	0.8	1.2	1.3	-0.9
Glaucoma (self-reported)	0.3	0.4	1.1	-0.6	-0.2	-0.2	-0.3	0.1	0.4	0.2	0.9	-0.3	-0.3	-0.8	-0.8	-0.7	-1.1	1.0
Gout (self-reported)	2.3	3.1	9.4	-2.2	-1.1	-1.4	-1.2	0.5	-0.1	1.3	0.0	-1.7	-1.3	-3.1	-2.5	-2.3	-2.1	2.3
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	2.3	-0.0	0.6	0.3	1.5	0.7	0.4	0.1	-0.4	0.4	-0.2	-0.1	-0.4	-0.1	-0.1	0.1
Medication: Amlodipine	0.4	0.5	2.1	-0.4	-0.2	-0.1	-0.8	1.0	1.5	0.7	-0.7	-0.3	-0.4	-0.6	-0.6	-0.4	-1.0	-0.6
Medication: Ventolin 100micrograms inhaler	3.5	4.5	11.7	2.7	3.2	3.4	0.1	1.6	0.5	1.3	0.6	3.3	2.2	1.1	1.6	2.5	0.9	-2.6
Birth weight	0.4	0.9	2.9	0.9	1.0	1.2	-0.2	-0.9	-1.2	-0.5	1.7	0.7	1.1	0.6	0.5	0.9	1.1	-0.3
Chronic bronchitis/emphysema (mother)	3.3	3.9	7.7	1.9	2.8	2.6	2.6	2.2	-1.9	2.0	0.6	2.4	2.2	1.5	0.9	1.8	0.8	-1.9
High blood pressure (siblings)	0.9	1.4	6.4	-0.9	-0.9	-0.9	-1.3	-2.5	-0.7	-2.0	-1.1	-0.8	-1.3	-0.4	-0.7	-0.8	-1.0	0.0
Forced vital capacity (FVC), Best measure	2.7	9.8	15.9	3.9	3.5	3.8	2.2	-0.4	-0.6	-1.5	4.0	3.2	4.0	3.2	3.3	3.9	3.9	-1.9
Body fat percentage	0.4	1.5	5.3	0.3	1.1	0.8	-1.5	2.2	1.6	2.3	-0.9	0.6	0.8	0.1	-0.1	0.3	-0.9	-1.5
Leg fat percentage (right)	0.3	1.1	4.4	-0.5	0.3	0.1	-1.0	2.0	2.1	1.5	-1.0	-0.4	0.2	-0.7	-0.8	-0.5	-1.3	-0.7
Arm fat-free mass (right)	1.1	5.5	10.4	2.8	3.0	2.9	-0.9	1.7	2.4	0.3	2.3	1.9	3.2	2.3	2.4	2.8	1.8	-2.5
Exposure to tobacco smoke outside home	0.6	0.8	3.6	0.5	0.6	0.7	-1.1	1.9	0.4	1.3	-0.8	0.9	0.3	0.1	0.3	0.5	-0.5	-1.2
Comparative body size at age 10	2.3	6.4	14.3	2.9	1.9	2.0	0.6	1.6	2.1	-0.1	3.8	1.4	3.2	3.4	3.1	3.0	3.7	-1.3
Number of full brothers	0.8	1.0	4.1	-0.6	-0.9	-0.7	-1.8	0.8	-1.4	2.0	-0.0	-0.6	-1.0	-0.4	-0.5	-0.6	-0.7	0.6
Worry too long after embarrassment	1.0	1.7	4.8	-1.7	-1.6	-1.7	0.2	-0.3	-1.4	-0.5	0.0	-1.9	-0.7	-1.2	-1.4	-1.6	-0.7	2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	2.1	2.7	5.4	-1.9	-1.4	-1.5	-1.9	-0.0	-0.8	0.5	-2.2	-1.1	-1.9	-1.5	-2.0	-1.9	-2.3	1.6
Wheeze or whistling in the chest in last year	4.3	7.7	17.6	3.3	4.1	4.2	-1.6	1.2	-2.3	1.8	1.2	4.0	3.1	2.0	1.9	3.1	0.9	-3.7
Number of children fathered	1.0	1.1	2.0	1.4	1.3	1.3	-0.1	0.5	-0.9	0.7	1.0	1.1	1.2	1.1	1.1	1.4	0.7	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.6	0.1	0.2	0.2	0.8	-0.3	0.2	-0.6	-0.1	-0.0	-0.0	-0.3	0.1	0.1	0.4	0.0
Age at first live birth	0.9	1.6	7.1	0.4	-0.5	-0.5	-1.1	-0.9	2.1	-0.2	2.7	-0.7	0.5	1.1	1.1	0.5	1.9	1.4
Pulse wave peak to peak time	0.5	0.6	2.2	0.5	1.4	1.5	0.5	0.1	-0.2	-0.2	-0.3	1.3	0.5	-0.6	-0.4	0.4	-0.7	-0.6
Health satisfaction	0.6	0.7	1.5	-1.0	-0.7	-0.8	-1.2	0.5	0.8	0.6	-0.4	-0.9	-0.5	-0.4	-0.9	-1.0	-1.2	1.2
Shortness of breath walking on level ground	0.1	0.2	0.7	-0.5	-0.2	-0.1	-0.2	0.2	0.4	0.5	-0.2	-0.4	-0.3	-0.5	-0.6	-0.5	-0.8	-0.0
Qualifications: College or University degree	2.2	6.9	12.6	3.3	2.1	2.5	-1.1	-1.7	1.7	-1.5	2.2	2.5	2.8	3.4	3.5	3.4	3.3	-2.5
Eye problems/disorders: None of the above	1.3	1.5	4.6	1.2	0.1	0.6	0.8	-0.6	-1.7	0.0	1.4	0.4	1.0	2.1	1.6	1.3	2.1	-0.7
Mouth/teeth dental problems: Loose teeth	0.8	1.0	4.0	-0.9	-0.9	-0.7	-1.1	0.9	-0.9	2.0	-0.0	-1.0	-0.8	-0.6	-0.7	-0.9	-0.5	1.4
Emphysema/chronic bronchitis	3.1	3.5	7.2	2.4	2.0	1.9	-1.4	1.0	0.7	0.1	0.7	2.1	2.3	2.7	2.2	2.4	1.9	-2.1
Medication for pain relief, constipation, heartburn	1.8	3.0	4.7	2.1	1.7	1.7	1.0	-1.5	0.3	-1.6	1.2	2.1	1.7	2.1	2.2	2.0	2.0	-1.9
Neck or shoulder pain in last month	0.2	0.3	2.2	-0.1	-0.5	-0.5	-0.5	-0.3	-1.5	0.6	-0.5	-0.4	-0.3	0.3	0.3	-0.0	-0.1	-0.2
Medication: Blood pressure	0.5	0.8	4.1	0.8	0.6	0.7	0.4	1.1	2.0	-0.5	0.4	0.6	0.8	0.7	0.7	0.8	-0.3	-1.3
Angina (self-reported)	4.8	6.3	11.2	-3.1	-3.0	-3.0	-2.3	-1.9	-0.6	-1.1	-0.6	-3.4	-2.9	-2.4	-2.7	-3.0	-2.2	3.2
Migraine (self-reported)	0.2	0.2	1.1	0.2	0.1	0.0	0.2	-1.1	-0.6	-0.7	-0.9	0.3	-0.1	0.7	0.1	0.2	0.4	-0.3
Medication: Ibuprofen	0.3	0.3	0.9	-0.5	-0.2	-0.2	-0.8	-0.3	0.1	0.6	-0.9	-0.4	-0.3	-0.7	-0.8	-0.5	-0.8	0.3
Medication: Allopurinol	1.1	1.5	5.7	-1.2	-0.8	-1.1	0.4	1.3	-0.4	2.4	0.6	-1.1	-0.9	-1.6	-1.1	-1.2	-0.9	1.7
Medication: Omeprazole	1.6	1.9	5.2	-1.3	-2.3	-1.9	0.7	-1.1	-1.6	-0.6	1.0	-2.2	-0.8	-0.1	-0.4	-1.1	-0.2	2.2
Medication: Seretide 50 evohaler	2.8	3.2	6.0	2.1	2.1	2.3	-0.3	1.4	-1.3	0.9	2.5	1.9	2.2	1.5	1.8	2.1	1.9	-1.5
Mean time to correctly identify matches	1.6	3.1	7.7	-2.1	-1.4	-1.5	0.8	0.1	0.3	1.0	-1.9	-1.2	-2.4	-2.2	-2.4	-2.2	-2.8	1.5
Heart disease (mother)	0.6	0.8	4.8	-0.3	-0.5	-0.4	-0.8	2.2	-0.2	2.1	0.4	-0.6	-0.1	-0.2	-0.2	-0.3	-0.4	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.4	0.2	-0.4	-0.2	-0.9	-0.8	-1.2	0.1	0.8	0.1	-0.2	0.7	0.5	0.2	0.7	-0.1
Whole body fat mass	0.5	2.2	5.0	1.2	1.8	1.6	-1.3	2.2	2.1	2.0	0.2	1.0	1.7	0.9	0.8	1.2	-0.0	-1.9
Leg fat mass (right)	0.4	1.4	5.8	0.6	1.2	1.0	-1.2	2.2	2.4	1.7	-0.0	0.4	1.2	0.5	0.3	0.6	-0.2	-1.3
Arm predicted mass (right)	1.1	5.6	11.1	2.9	3.1	3.0	-0.7	1.5	2.4	0.1	2.2	2.0	3.3	2.3	2.4	2.9	1.8	-2.6
Pulse rate, automated reading	0.2	0.7	2.1	-0.8	-1.4	-1.4	-0.8	-1.1	0.4	0.0	-1.0	-1.0	-0.7	0.2	0.0	-0.6	-0.7	0.0
Alcohol intake frequency.	0.3	0.7	2.0	-0.8	-0.4	-0.5	1.3	0.8	-0.9	-0.7	-1.4	-0.5	-1.1	-0.5	-0.9	-0.8	-0.8	0.4
Comparative height size at age 10	2.9	16.2	27.9	5.3	4.5	4.7	-0.1	0.8	1.4	-2.2	4.7	4.0	5.0	4.7	4.6	5.2	4.3	-3.3
Number of full sisters	1.1	1.3	7.4	-0.9	-1.1	-1.1	1.3	-1.6	-2.7	-0.1	-1.2	-0.6	-1.3	-0.2	-0.3	-0.8	-0.1	0.3
Suffer from ‘nerves’	0.7	1.1	2.1	-1.3	-1.3	-1.1	-0.7	-1.4	-0.2	-0.5	-1.1	-1.1	-0.6	-1.1	-1.1	-1.3	-1.1	0.8
Overall health rating	1.5	3.1	6.0	-2.2	-2.4	-2.4	-1.5	0.4	-1.8	1.1	-1.4	-2.1	-1.8	-1.3	-1.5	-2.1	-1.9	1.6
Chest pain or discomfort	0.3	0.4	2.1	0.3	0.5	0.7	-0.8	-0.4	-1.4	-0.1	-0.3	0.6	0.3	-0.0	0.1	0.3	-0.3	-1.1
Had major operations	0.1	0.1	0.7	0.1	-0.3	-0.1	0.8	0.2	-0.4	0.5	0.3	-0.1	-0.1	0.5	0.1	0.1	0.2	0.1
Age at last live birth	0.6	0.9	3.3	0.7	0.2	0.3	-0.6	-0.7	1.3	-0.1	1.8	0.1	0.9	1.0	0.9	0.7	1.6	0.9
Family relationship satisfaction	0.8	1.0	3.7	-1.1	-0.8	-0.7	0.3	-1.9	0.6	-1.0	-0.6	-0.9	-0.4	-0.9	-1.0	-1.2	-1.0	1.5
Leg pain on walking	0.9	1.2	9.1	-0.7	0.3	0.1	-3.0	0.1	-0.5	-0.5	-1.3	0.0	-0.7	-0.8	-1.4	-0.8	-1.4	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.2	-0.2	0.1	0.2	0.4	0.3	-0.5	0.8	-1.1	0.8	-0.2	-0.7	-0.4	-0.2	-1.0	-1.0
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.9	0.5	0.4	0.3	-0.7	1.3	0.5	1.4	-0.7	0.9	0.5	0.4	0.6	0.5	-0.3	-1.3
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.2	0.4	0.0	-0.1	1.1	-0.7	1.0	-1.0	0.0	0.2	0.3	0.5	0.7	0.4	0.6	-0.5
Medication: Aspirin	1.2	1.6	4.7	-1.5	-1.4	-1.3	-0.2	0.9	-0.2	0.8	-0.8	-1.1	-1.5	-1.7	-1.5	-1.5	-2.2	0.9
Supplements: Vitamin C	0.5	0.6	3.9	0.6	1.0	1.0	2.0	0.2	0.2	0.7	0.2	1.0	1.1	-0.0	0.0	0.5	-0.4	-0.6
Knee pain experienced in last month	0.4	0.6	2.1	0.4	1.3	1.2	-0.8	-0.7	-0.2	-1.4	0.6	0.9	0.8	-0.0	-0.4	0.2	-0.5	0.3
Hypertension (Self-reported)	0.4	1.1	5.4	0.6	1.0	1.3	-1.5	0.2	-0.2	-0.9	-0.3	1.2	0.8	0.1	-0.0	0.6	-1.4	-2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	5.6	-1.2	-2.4	-1.9	0.9	0.0	0.1	0.8	1.1	-2.2	-1.2	0.3	-0.1	-1.0	0.7	2.1
Illnesses of father: Heart disease	2.5	3.4	10.9	-1.8	-2.7	-2.8	-0.4	-1.8	0.7	-2.6	-0.3	-3.3	-1.7	-0.5	-0.4	-1.6	0.1	2.3
Illnesses of siblings: Diabetes	2.4	2.9	6.1	-1.9	-2.1	-2.0	-1.0	-1.8	-1.4	-0.3	-2.0	-1.5	-2.5	-1.5	-1.4	-1.9	-2.2	0.7
Smoking status: Previous	0.9	1.3	4.5	1.4	0.9	0.6	-0.4	0.6	-0.2	-0.7	0.3	0.8	1.3	1.8	1.7	1.4	2.1	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	2.2	4.7	10.7	2.7	3.2	3.3	0.2	-0.3	0.7	-0.5	1.3	2.9	3.1	2.0	1.8	2.6	1.5	-2.2
Whole body fat-free mass	1.0	5.7	9.9	2.9	2.8	2.9	-0.4	1.1	2.8	-0.1	2.6	1.9	3.1	2.5	2.6	2.9	2.1	-2.2
Leg fat-free mass (right)	0.7	3.7	7.5	2.2	2.1	2.2	-0.5	1.4	2.7	0.5	2.5	1.1	2.3	2.2	2.0	2.2	1.6	-1.4
Arm fat percentage (left)	0.4	1.7	7.5	-0.7	0.1	-0.1	-1.3	2.0	1.9	2.7	-1.6	-0.4	-0.3	-0.8	-1.0	-0.8	-1.7	-0.4
Average weekly red wine intake	2.3	3.4	5.8	2.4	2.1	2.2	-0.7	-1.0	-0.3	-1.1	1.7	2.0	2.3	2.0	2.0	2.3	2.3	-1.7
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.0	-0.3	0.5	0.4	-0.8	-1.1	-1.3	-0.2	-1.4	0.6	-0.3	-1.3	-0.8	-0.3	-1.4	-0.5
Mood swings	0.8	1.5	3.6	-1.5	-0.8	-1.0	-1.4	0.0	-0.2	0.4	-1.9	-0.9	-0.8	-1.6	-1.7	-1.5	-1.5	1.1
Loneliness, isolation	0.6	0.9	3.4	-0.8	-0.8	-0.7	-1.5	-1.8	-1.7	-0.2	-0.9	-0.5	-0.3	-0.5	-0.5	-0.7	-0.7	0.6
Long-standing illness, disability or infirmity	3.2	4.9	10.2	-2.5	-1.8	-2.1	-2.6	-1.2	1.0	-0.3	-2.5	-2.1	-2.3	-2.6	-2.7	-2.6	-3.2	2.0
Ever had bowel cancer screening	0.7	0.9	2.3	-1.1	-1.2	-1.5	-0.1	-0.8	-0.1	-0.9	-1.0	-1.0	-1.3	-0.6	-0.6	-1.0	-0.8	0.5
Diabetes diagnosed by doctor	2.5	4.1	8.7	-2.4	-2.0	-2.1	-1.0	-2.5	-0.2	-1.1	-1.3	-2.0	-2.6	-2.0	-2.0	-2.4	-2.9	2.0
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.3	-0.1	0.6	0.5	-0.8	1.5	-0.9	0.9	0.2	0.4	0.4	-0.6	-0.7	-0.2	-0.9	0.4
Friendships satisfaction	0.8	0.9	3.9	-0.8	-0.5	-0.6	-0.1	-2.0	0.7	-1.8	-0.6	-0.6	-0.4	-1.1	-0.8	-0.8	-0.5	1.2
Qualifications: nursing, teaching	1.5	2.3	6.4	1.7	1.6	1.5	2.5	-0.3	-0.0	-2.0	1.0	1.6	1.6	1.5	1.6	1.7	0.9	-1.6
Commuting to job workplace: Walk	0.6	0.6	2.0	0.8	1.3	1.3	-0.2	-0.1	0.4	-1.0	1.4	0.6	1.0	0.2	0.3	0.8	0.3	-0.4
Eye problems/disorders: Cataract	0.9	1.0	4.0	-0.2	0.8	0.3	-0.2	0.9	0.7	-0.7	-2.0	1.0	-0.3	-1.5	-0.9	-0.3	-1.9	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.1	-0.1	-0.7	-0.4	1.1	-0.4	0.7	-0.6	0.5	-0.7	0.6	0.2	0.3	-0.1	0.7	0.7
Medication for cholesterol	0.7	1.0	5.3	0.9	1.2	0.9	2.3	0.5	1.7	-0.8	0.2	1.0	0.7	0.9	0.7	0.8	0.3	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.9	2.2	6.0	-1.9	-1.9	-1.6	0.8	-1.1	1.0	-0.8	0.2	-2.3	-1.3	-0.8	-1.5	-1.8	-0.8	2.5
Back pain experienced in last month	0.7	1.0	3.7	-0.6	-1.9	-1.7	-0.4	0.2	1.1	-0.4	-0.5	-1.8	-0.8	0.7	0.4	-0.4	0.7	1.0
Mineral and other dietary supplements	1.3	1.8	5.4	-1.3	-2.3	-2.2	-0.8	-0.2	0.7	0.9	0.9	-2.3	-1.3	0.0	-0.2	-1.1	-0.1	1.8
Breast cancer (self-reported)	0.9	1.1	3.9	0.3	-0.8	-0.5	1.2	-0.1	-1.6	0.3	2.0	-0.8	-0.5	0.9	0.9	0.4	1.8	1.0
Asthma (self-reported)	6.6	13.1	33.4	4.5	5.6	5.8	-0.3	1.8	-0.9	1.9	0.8	5.8	3.9	2.4	2.5	4.2	1.3	-4.8
Osteoporosis (self-reported)	0.6	0.7	3.0	-0.2	-1.1	-1.1	-0.9	1.7	-0.3	1.5	-0.5	-0.6	-0.8	0.6	0.6	-0.1	0.6	-0.3
Osteoarthritis (self-reported)	1.1	1.4	3.4	-1.3	-0.5	-0.6	-0.1	0.7	1.8	0.7	-1.5	-0.8	-1.1	-1.8	-1.6	-1.3	-1.5	0.5
Medication: Aspirin	1.7	2.2	5.9	-1.8	-1.5	-1.5	-0.5	0.9	-0.0	1.0	-1.2	-1.3	-1.8	-2.0	-1.8	-1.8	-2.4	1.2
Medication: Gliclazide	2.3	2.6	6.6	-1.5	-0.9	-1.1	-0.4	-2.4	0.1	-1.9	-2.6	-0.8	-1.6	-2.1	-1.6	-1.6	-2.3	0.3
Illnesses of father: None of the above (group 1)	2.5	3.1	7.1	1.9	2.5	2.7	1.3	1.7	-0.7	2.5	1.1	2.5	2.0	1.0	0.9	1.8	0.7	-1.4
Smoking status: Current	0.6	1.0	5.0	-0.8	0.1	-0.1	-2.0	-0.4	-2.2	0.3	-0.5	0.4	-0.8	-0.9	-1.2	-0.8	-1.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.6	7.7	-1.7	-2.0	-2.3	1.9	-0.6	0.7	-1.0	0.8	-2.5	-1.3	-1.4	-1.1	-1.6	-0.2	2.8
Whole body water mass	1.0	6.0	10.4	3.0	2.9	3.0	-0.4	1.2	2.7	0.0	2.7	1.9	3.2	2.6	2.7	3.0	2.2	-2.3
Leg predicted mass (right)	0.7	3.6	7.5	2.1	2.1	2.1	-0.5	1.4	2.7	0.5	2.5	1.1	2.3	2.1	2.0	2.2	1.6	-1.3
Arm fat mass (left)	0.3	1.2	4.8	0.3	0.9	0.7	-1.1	1.9	2.2	2.0	-0.5	0.1	0.7	0.0	-0.0	0.2	-0.8	-1.0
Number of self-reported non-cancer illnesses	0.2	0.4	0.9	-0.7	-0.8	-0.7	0.2	0.3	0.7	0.2	-0.3	-1.0	-0.4	-0.5	-0.6	-0.7	-1.0	0.4
Average weekly champagne plus white wine intake	5.3	7.3	12.6	3.5	3.3	3.3	-0.9	0.0	0.2	-0.2	2.2	3.3	3.3	2.8	3.1	3.5	2.8	-3.1
Miserableness	0.3	0.5	2.0	0.7	0.5	0.5	-0.2	-0.9	-0.3	-1.4	-0.2	0.7	0.7	0.9	0.7	0.7	1.0	-0.6
Guilty feelings	0.8	1.2	6.7	-0.8	-0.9	-1.0	-2.6	-1.7	-1.3	-1.1	-0.1	-0.7	0.1	-0.5	-0.6	-0.7	-0.4	1.2
Wears glasses or contact lenses	0.4	0.5	1.4	-0.7	-0.9	-1.0	-0.0	-1.1	0.3	-0.3	-1.2	-0.6	-1.1	-0.5	-0.3	-0.7	-0.3	0.0
Ever taken oral contraceptive pill	0.6	0.6	2.5	0.6	0.5	0.5	-1.4	0.4	1.6	0.8	0.6	0.5	0.3	0.7	0.8	0.7	0.8	-0.3
Hearing aid user	0.9	1.0	6.9	-0.3	0.7	0.5	-2.6	1.2	-0.5	0.9	-1.1	0.4	-0.3	-0.9	-1.0	-0.4	-1.3	-0.6
Mother’s age at death	0.6	0.7	4.9	-0.7	-0.0	-0.4	-0.3	-0.1	0.3	-0.1	-2.2	0.0	-1.0	-1.2	-1.0	-0.8	-1.1	0.3
Financial situation satisfaction	3.4	4.2	6.8	-2.5	-2.5	-2.6	-2.6	-0.9	-1.1	1.2	-1.5	-2.1	-2.6	-1.6	-1.9	-2.4	-1.5	2.5
Tinnitus: Yes, now most or all of the time	0.5	0.6	5.2	0.5	0.3	0.1	0.1	0.8	-2.3	0.8	1.0	0.1	0.5	0.5	0.7	0.5	0.2	-0.4
Commuting to job workplace: Public transport	0.3	0.3	1.8	0.3	0.7	0.7	0.5	-0.7	-0.9	-1.4	-0.1	0.7	0.1	-0.1	-0.3	0.2	0.1	-0.1
Eye problems/disorders: Glaucoma	2.0	2.3	4.3	-1.9	-1.5	-1.4	-1.1	-0.2	1.2	0.3	-0.2	-1.6	-1.4	-2.1	-1.9	-1.9	-2.1	2.0
Medication: Blood pressure	0.2	0.4	2.7	-0.6	-0.7	-0.5	-1.6	-0.7	-0.6	-0.4	0.1	-0.7	-0.3	-0.2	-0.6	-0.5	-0.4	0.1
Pain type(s) experienced in last month: Hip pain	0.5	0.6	3.1	-0.3	-0.3	-0.3	-1.8	-0.8	-1.0	-1.0	-1.5	-0.2	-0.6	-0.3	-0.1	-0.2	-0.5	-0.8
Supplements: Fish oil (including cod liver oil)	0.6	0.7	3.1	0.5	1.0	0.9	1.3	0.6	-0.1	-0.8	-1.8	1.2	0.2	-0.2	-0.0	0.4	-0.2	-1.3
High cholesterol (Self-reported)	3.7	6.6	12.1	-3.4	-3.4	-3.2	-0.0	-0.6	0.2	0.6	-0.7	-3.5	-2.5	-2.9	-3.0	-3.4	-2.6	3.3
Medication: Bendroflumethiazide	0.8	1.3	3.0	1.1	1.4	1.6	0.3	0.0	1.2	-0.8	1.5	1.2	1.7	0.9	0.6	1.1	0.5	-1.2
Medication: Paracetamol	1.1	1.8	10.1	0.5	1.4	1.3	-1.8	2.6	0.3	3.2	-1.0	0.8	0.6	-0.1	-0.4	0.3	-0.1	-0.3
Medication: Lisinopril	0.5	0.6	3.0	0.2	0.3	0.5	-1.7	-1.0	-0.4	-0.9	-1.2	0.8	0.0	0.1	-0.1	0.1	-0.5	-1.4
Medication: Atorvastatin	0.9	1.1	2.2	-1.1	-1.2	-1.1	-1.5	0.8	-0.6	1.0	0.6	-1.4	-0.6	-0.8	-0.8	-1.1	-1.0	1.2
Illnesses of father: High blood pressure	0.2	0.3	2.4	-0.0	-0.4	-0.5	-0.2	-1.5	-0.3	-1.0	-0.5	-0.2	-0.4	0.2	0.1	-0.0	0.1	-0.2
Alcohol drinker status: Never	1.5	1.8	6.2	1.1	0.1	0.2	0.9	1.6	-1.1	1.1	2.5	0.1	0.7	1.8	1.6	1.2	2.3	0.3
Ever smoked	0.3	0.6	1.4	0.8	0.9	0.6	-1.2	0.3	-0.3	-0.6	-0.0	0.9	0.7	0.8	0.8	0.8	0.8	-1.1
Basal metabolic rate	1.0	5.7	10.5	2.9	3.0	3.0	-0.5	1.3	2.8	0.2	2.4	1.9	3.2	2.4	2.5	2.9	1.9	-2.4
Leg fat percentage (left)	0.3	0.9	4.2	-0.2	0.4	0.2	-1.1	1.9	2.1	1.4	-0.7	-0.2	0.4	-0.4	-0.5	-0.2	-1.0	-0.7
Arm fat-free mass (left)	1.2	6.3	11.9	3.1	3.2	3.1	-0.5	1.4	2.5	-0.1	2.5	2.1	3.4	2.5	2.7	3.1	2.1	-2.6
Number of operations (self-reported)	0.5	0.7	2.9	-0.4	-0.3	-0.2	1.1	0.2	-1.7	1.6	1.3	-0.3	-0.3	-0.2	-0.7	-0.4	-0.1	1.2
Average weekly beer plus cider intake	4.4	6.4	10.8	-3.3	-2.9	-3.1	-0.4	-0.4	-1.7	1.2	-1.7	-2.9	-3.1	-2.8	-2.8	-3.3	-2.4	2.9
Irritability	0.8	1.4	6.1	-1.3	-1.4	-1.7	0.8	-0.8	-0.4	-0.9	0.5	-1.8	-0.7	-0.4	-0.8	-1.2	-0.2	2.5
Risk taking	0.4	0.6	1.9	-0.7	-0.0	-0.3	-0.7	1.0	-0.2	1.2	-0.2	0.2	-1.1	-0.7	-0.9	-0.7	-1.4	0.4
Ever had prostate specific antigen (PSA) test	1.5	1.7	4.5	1.6	0.9	0.9	-0.4	-0.5	-0.8	-1.1	0.9	0.9	1.6	1.9	1.8	1.7	2.1	-0.9
Fractured/broken bones in last 5 years	1.0	1.3	5.4	1.0	0.7	0.6	-2.3	-0.4	-2.0	0.2	0.8	1.1	0.8	1.4	1.0	1.0	0.7	-1.0
Age started oral contraceptive pill	1.7	2.1	6.2	-1.5	-1.0	-0.9	-1.4	-2.5	-0.9	-2.0	-0.1	-1.1	-1.2	-1.9	-1.6	-1.6	-1.1	1.3
Diastolic blood pressure, automated reading	0.5	1.6	4.2	1.1	1.5	1.4	-1.5	1.8	2.0	0.0	-0.2	1.1	1.5	0.7	0.8	1.1	-0.0	-1.8
Ever depressed for a whole week	1.8	2.2	4.2	-1.8	-1.8	-1.6	-1.0	-1.4	1.4	-1.1	-0.9	-1.9	-1.1	-1.4	-1.4	-1.8	-1.1	2.0
Unable to work because of sickness or disability	1.6	2.0	3.4	-1.7	-1.8	-1.7	-1.6	0.8	-0.6	1.7	-0.9	-1.7	-1.5	-1.1	-1.3	-1.6	-1.1	1.5
Commuting to job workplace: Cycle	0.5	0.6	2.7	0.0	-0.1	0.1	0.1	-1.6	-0.4	-1.4	1.3	-0.6	0.6	0.1	-0.1	-0.0	0.8	1.2
Myopia	0.6	0.9	2.4	1.0	0.6	0.7	-0.7	1.0	-0.6	0.7	1.6	0.7	0.9	1.0	1.1	1.1	1.2	-0.4
Vascular/heart problems diagnosed by doctor	0.3	0.9	3.8	0.5	-0.1	-0.2	1.8	0.6	-0.3	1.4	0.9	0.1	0.2	0.9	1.0	0.5	2.0	1.1
Cholesterol lowering medication	7.4	10.9	19.5	-4.4	-3.9	-3.8	-1.1	-1.4	-1.2	0.2	-1.4	-4.2	-3.3	-4.1	-3.9	-4.4	-3.5	4.0
Medication: Omeprazole (e.g. Zanprol)	2.5	3.1	7.5	-2.1	-2.7	-2.5	0.8	-1.1	-1.5	-0.8	0.0	-2.7	-1.5	-1.1	-1.3	-1.9	-0.9	2.6
Pain experienced in last month	0.2	0.3	1.2	-0.6	-0.3	-0.3	1.0	-0.2	1.1	0.6	-0.6	-0.1	-0.5	-0.8	-0.5	-0.5	-0.4	0.2
Supplements: Calcium	0.4	0.4	1.9	0.5	-0.3	-0.1	0.7	1.4	0.2	0.8	-0.4	0.0	0.1	0.8	0.9	0.6	0.8	-0.1
Basal cell carcinoma (self-reported)	0.2	0.2	1.4	0.1	-0.1	-0.1	-0.5	-0.2	0.0	1.2	-0.5	0.3	-0.1	-0.1	0.4	0.1	0.1	-0.8
Heart attack/myocardial infarction (self-reported)	3.4	4.4	7.6	-2.5	-2.5	-2.7	-1.3	-2.3	0.4	-1.7	-0.7	-2.8	-2.7	-1.8	-2.0	-2.5	-1.6	2.5
Deep venous thrombosis (DVT) (self-reported)	3.3	4.3	8.1	-2.7	-2.8	-2.5	-0.4	-1.6	-0.3	-0.2	-0.3	-2.8	-2.5	-2.0	-2.2	-2.7	-1.6	2.7
Heart disease (siblings)	2.1	2.6	8.5	-1.9	-2.9	-2.7	0.5	-0.5	-0.5	0.3	-1.1	-2.7	-2.0	-0.5	-0.7	-1.7	-0.4	1.6
Alcohol drinker status: Previous	0.7	0.8	2.8	-0.8	-1.0	-1.1	1.3	-0.5	-1.7	-0.7	0.2	-0.9	-0.8	-0.5	-0.3	-0.8	-0.1	0.9
Pack years of smoking	1.9	2.8	7.7	-2.0	-1.3	-1.2	-0.7	-2.2	-1.0	-0.9	-0.8	-1.1	-2.0	-2.0	-2.3	-2.0	-2.8	1.0
Impedance of whole body	0.3	1.6	7.1	1.2	0.9	1.1	-0.3	-1.1	-2.7	-0.6	-0.5	1.9	0.7	1.3	1.1	1.2	1.0	-1.6
Leg fat mass (left)	0.4	1.6	5.5	0.8	1.3	1.1	-1.3	2.1	2.4	1.6	0.2	0.5	1.4	0.7	0.5	0.8	-0.1	-1.4
Arm predicted mass (left)	1.2	6.1	11.5	3.0	3.0	3.0	-0.6	1.4	2.6	-0.2	2.5	2.0	3.4	2.5	2.6	3.0	2.1	-2.5