[Hub]/) : Traits : Systolic Blood Pressure :

chr22:37,394,391-38,907,849

Best TWAS P=3.53e-09 · Best GWAS P=5.23e-08 conditioned to 0.677

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TRIOBP 0.20 0.20 bslmm 501 0.21 4.3e-25 5.2 -5.2 1.6e-07 -0.95 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous TRIOBP 0.13 0.14 lasso 7 0.14 3.9e-11 5.4 -5.5 4.0e-08 -0.97 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous GCAT 0.16 0.12 lasso 5 0.12 9.2e-10 5.3 5.5 3.7e-08 0.92 0.01 0.99 FALSE
4 GTEx Adipose Visceral Omentum TRIOBP 0.16 0.14 enet 28 0.12 5.6e-07 5.4 -5.5 3.9e-08 -0.91 0.01 0.99 FALSE
5 GTEx Artery Aorta TRIOBP 0.13 0.10 lasso 8 0.11 1.1e-06 5.4 -5.4 6.1e-08 -0.97 0.01 0.99 FALSE
6 GTEx Artery Aorta GCAT 0.16 0.15 lasso 2 0.14 5.4e-08 5.4 5.4 6.8e-08 0.95 0.01 0.99 FALSE
7 GTEx Breast Mammary Tissue TRIOBP 0.11 0.10 enet 13 0.09 3.3e-05 5.4 -5.3 1.1e-07 -0.96 0.01 0.99 FALSE
8 GTEx Cells Transformed fibroblasts TRIOBP 0.08 0.03 enet 11 0.09 3.0e-07 5.2 -5.1 2.7e-07 -0.94 0.02 0.98 FALSE
9 GTEx Colon Sigmoid TRIOBP 0.28 0.22 lasso 6 0.22 2.7e-08 5.3 -5.4 8.5e-08 -0.90 0.01 0.99 FALSE
10 GTEx Esophagus Muscularis GCAT 0.11 0.12 lasso 3 0.12 1.1e-07 5.4 5.2 2.5e-07 0.93 0.02 0.98 FALSE
11 GTEx Heart Atrial Appendage TRIOBP 0.15 0.13 lasso 6 0.11 1.3e-05 5.2 -5.4 8.5e-08 -0.99 0.01 0.99 FALSE
12 GTEx Heart Left Ventricle TRIOBP 0.16 0.04 lasso 4 0.08 6.2e-05 5.2 -5.3 1.2e-07 -0.92 0.02 0.97 FALSE
13 GTEx Lung TRIOBP 0.16 0.10 enet 10 0.12 8.7e-10 5.2 -5.2 1.9e-07 -0.95 0.01 0.99 FALSE
14 GTEx Lung GCAT 0.10 0.09 lasso 2 0.07 9.7e-06 5.4 5.4 6.1e-08 0.95 0.01 0.99 FALSE
15 GTEx Nerve Tibial TRIOBP 0.20 0.18 lasso 7 0.22 9.1e-16 5.4 -5.3 1.4e-07 -0.95 0.01 0.99 FALSE
16 GTEx Pancreas GCAT 0.32 0.23 lasso 6 0.26 2.4e-11 5.0 -5.3 9.9e-08 -0.71 0.07 0.93 FALSE
17 GTEx Skin Not Sun Exposed Suprapubic TRIOBP 0.12 0.04 lasso 3 0.05 7.0e-04 4.9 -5.3 8.8e-08 -0.94 0.02 0.97 FALSE
18 GTEx Skin Sun Exposed Lower leg TRIOBP 0.06 0.06 lasso 4 0.06 1.7e-05 4.9 -5.1 2.8e-07 -0.90 0.03 0.96 FALSE
19 GTEx Stomach TRIOBP 0.10 0.03 lasso 5 0.03 1.9e-02 5.4 -5.6 2.4e-08 -0.98 0.02 0.92 FALSE
20 GTEx Whole Blood TRIOBP 0.18 0.05 enet 29 0.14 1.7e-12 5.4 -5.9 4.7e-09 -0.77 0.01 0.99 FALSE
21 YFS Blood TRIOBP 0.38 0.28 bslmm 488 0.39 3.0e-136 5.4 -5.6 2.0e-08 -0.83 0.01 0.99 FALSE
22 The Cancer Genome Atlas Breast Invasive Carcinoma TRIOBP 0.04 0.05 enet 16 0.06 3.0e-13 5.4 -5.3 1.5e-07 -0.91 0.01 0.99 FALSE
23 The Cancer Genome Atlas Colon Adenocarcinoma GCAT 0.09 0.08 enet 6 0.08 3.1e-05 5.3 5.9 3.7e-09 0.91 0.01 0.98 FALSE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRIOBP 0.11 0.09 enet 10 0.11 5.5e-12 4.9 -5.9 3.5e-09 -0.89 0.03 0.97 TRUE
25 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma GCAT 0.13 0.03 blup 29 0.08 3.6e-05 -4.0 5.3 1.0e-07 0.69 0.01 0.84 FALSE
26 The Cancer Genome Atlas Brain Lower Grade Glioma ANKRD54 0.05 0.01 blup 31 0.02 1.3e-03 5.3 -5.3 1.1e-07 -0.88 0.01 0.91 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma TRIOBP 0.08 0.07 enet 11 0.08 6.1e-09 4.1 -5.1 2.6e-07 -0.88 0.06 0.94 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma TRIOBP 0.07 0.04 blup 67 0.03 2.1e-04 4.4 -5.4 5.3e-08 -0.86 0.06 0.92 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma GCAT 0.02 0.03 blup 29 0.03 1.4e-03 5.4 5.7 1.6e-08 0.95 0.01 0.86 FALSE
30 The Cancer Genome Atlas Thyroid Carcinoma TRIOBP 0.22 0.25 enet 37 0.27 6.9e-26 5.4 -5.1 2.8e-07 -0.90 0.01 0.99 FALSE