[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr22:37,394,391-38,907,849

Best TWAS P=3.53e-09 · Best GWAS P=5.23e-08 conditioned to 0.677

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TRIOBP	0.20	0.20	bslmm	501	0.21	4.3e-25	5.2	-5.2	1.6e-07	-0.95	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	TRIOBP	0.13	0.14	lasso	7	0.14	3.9e-11	5.4	-5.5	4.0e-08	-0.97	0.01	0.99	FALSE
3	GTEx	Adipose Subcutaneous	GCAT	0.16	0.12	lasso	5	0.12	9.2e-10	5.3	5.5	3.7e-08	0.92	0.01	0.99	FALSE
4	GTEx	Adipose Visceral Omentum	TRIOBP	0.16	0.14	enet	28	0.12	5.6e-07	5.4	-5.5	3.9e-08	-0.91	0.01	0.99	FALSE
5	GTEx	Artery Aorta	TRIOBP	0.13	0.10	lasso	8	0.11	1.1e-06	5.4	-5.4	6.1e-08	-0.97	0.01	0.99	FALSE
6	GTEx	Artery Aorta	GCAT	0.16	0.15	lasso	2	0.14	5.4e-08	5.4	5.4	6.8e-08	0.95	0.01	0.99	FALSE
7	GTEx	Breast Mammary Tissue	TRIOBP	0.11	0.10	enet	13	0.09	3.3e-05	5.4	-5.3	1.1e-07	-0.96	0.01	0.99	FALSE
8	GTEx	Cells Transformed fibroblasts	TRIOBP	0.08	0.03	enet	11	0.09	3.0e-07	5.2	-5.1	2.7e-07	-0.94	0.02	0.98	FALSE
9	GTEx	Colon Sigmoid	TRIOBP	0.28	0.22	lasso	6	0.22	2.7e-08	5.3	-5.4	8.5e-08	-0.90	0.01	0.99	FALSE
10	GTEx	Esophagus Muscularis	GCAT	0.11	0.12	lasso	3	0.12	1.1e-07	5.4	5.2	2.5e-07	0.93	0.02	0.98	FALSE
11	GTEx	Heart Atrial Appendage	TRIOBP	0.15	0.13	lasso	6	0.11	1.3e-05	5.2	-5.4	8.5e-08	-0.99	0.01	0.99	FALSE
12	GTEx	Heart Left Ventricle	TRIOBP	0.16	0.04	lasso	4	0.08	6.2e-05	5.2	-5.3	1.2e-07	-0.92	0.02	0.97	FALSE
13	GTEx	Lung	TRIOBP	0.16	0.10	enet	10	0.12	8.7e-10	5.2	-5.2	1.9e-07	-0.95	0.01	0.99	FALSE
14	GTEx	Lung	GCAT	0.10	0.09	lasso	2	0.07	9.7e-06	5.4	5.4	6.1e-08	0.95	0.01	0.99	FALSE
15	GTEx	Nerve Tibial	TRIOBP	0.20	0.18	lasso	7	0.22	9.1e-16	5.4	-5.3	1.4e-07	-0.95	0.01	0.99	FALSE
16	GTEx	Pancreas	GCAT	0.32	0.23	lasso	6	0.26	2.4e-11	5.0	-5.3	9.9e-08	-0.71	0.07	0.93	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	TRIOBP	0.12	0.04	lasso	3	0.05	7.0e-04	4.9	-5.3	8.8e-08	-0.94	0.02	0.97	FALSE
18	GTEx	Skin Sun Exposed Lower leg	TRIOBP	0.06	0.06	lasso	4	0.06	1.7e-05	4.9	-5.1	2.8e-07	-0.90	0.03	0.96	FALSE
19	GTEx	Stomach	TRIOBP	0.10	0.03	lasso	5	0.03	1.9e-02	5.4	-5.6	2.4e-08	-0.98	0.02	0.92	FALSE
20	GTEx	Whole Blood	TRIOBP	0.18	0.05	enet	29	0.14	1.7e-12	5.4	-5.9	4.7e-09	-0.77	0.01	0.99	FALSE
21	YFS	Blood	TRIOBP	0.38	0.28	bslmm	488	0.39	3.0e-136	5.4	-5.6	2.0e-08	-0.83	0.01	0.99	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIOBP	0.04	0.05	enet	16	0.06	3.0e-13	5.4	-5.3	1.5e-07	-0.91	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	GCAT	0.09	0.08	enet	6	0.08	3.1e-05	5.3	5.9	3.7e-09	0.91	0.01	0.98	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TRIOBP	0.11	0.09	enet	10	0.11	5.5e-12	4.9	-5.9	3.5e-09	-0.89	0.03	0.97	TRUE
25	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	GCAT	0.13	0.03	blup	29	0.08	3.6e-05	-4.0	5.3	1.0e-07	0.69	0.01	0.84	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	ANKRD54	0.05	0.01	blup	31	0.02	1.3e-03	5.3	-5.3	1.1e-07	-0.88	0.01	0.91	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRIOBP	0.08	0.07	enet	11	0.08	6.1e-09	4.1	-5.1	2.6e-07	-0.88	0.06	0.94	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	TRIOBP	0.07	0.04	blup	67	0.03	2.1e-04	4.4	-5.4	5.3e-08	-0.86	0.06	0.92	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	GCAT	0.02	0.03	blup	29	0.03	1.4e-03	5.4	5.7	1.6e-08	0.95	0.01	0.86	FALSE
30	The Cancer Genome Atlas	Thyroid Carcinoma	TRIOBP	0.22	0.25	enet	37	0.27	6.9e-26	5.4	-5.1	2.8e-07	-0.90	0.01	0.99	FALSE