Hub : Genes

GCAT

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1650	0.0540	1.2e-05	0.118	NA	0.115	NA	0.117	7.7e-10	NA	1.2e-09	NA	9.2e-10
2	GTEx	Adipose Visceral Omentum	0.1350	0.0600	2.7e-03	0.024	NA	0.030	NA	0.034	2.1e-02	NA	1.1e-02	NA	7.2e-03
3	GTEx	Artery Aorta	0.1570	0.0550	5.9e-05	0.152	NA	0.086	NA	0.137	9.9e-09	NA	1.9e-05	NA	5.4e-08
4	GTEx	Artery Tibial	0.0912	0.0354	9.8e-05	0.091	NA	0.069	NA	0.085	1.3e-07	NA	4.7e-06	NA	3.5e-07
5	GTEx	Colon Transverse	0.2200	0.0860	4.9e-03	-0.006	NA	0.142	NA	-0.004	1.0e+00	NA	2.8e-07	NA	5.7e-01
6	GTEx	Esophagus Muscularis	0.1060	0.0360	3.1e-05	0.115	NA	0.109	NA	0.119	1.8e-07	NA	3.8e-07	NA	1.1e-07
7	GTEx	Lung	0.0968	0.0340	1.1e-04	0.090	NA	0.057	NA	0.065	2.2e-07	NA	3.8e-05	NA	9.7e-06
8	GTEx	Muscle Skeletal	0.1322	0.0360	8.1e-08	0.097	NA	0.101	NA	0.100	9.7e-10	NA	3.9e-10	NA	5.3e-10
9	GTEx	Pancreas	0.3160	0.0820	1.6e-07	0.228	NA	0.236	NA	0.259	5.2e-10	NA	2.3e-10	NA	2.4e-11
10	GTEx	Whole Blood	0.2350	0.0510	1.1e-08	0.187	NA	0.184	NA	0.186	5.2e-17	NA	9.1e-17	NA	6.1e-17
11	YFS	Blood	0.4991	0.0362	0.0e+00	0.397	0.384	0.432	0.431	0.434	5.4e-141	6.6e-135	1.9e-157	1.3e-156	3.2e-158
12	TCGA	Colon Adenocarcinoma	0.0940	0.0520	2.5e-04	0.082	0.068	0.077	NA	0.076	1.8e-05	9.0e-05	3.1e-05	NA	3.5e-05
13	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1340	0.0630	2.1e-04	0.027	0.077	0.066	NA	0.070	1.0e-02	3.7e-05	1.2e-04	NA	7.5e-05
14	TCGA	Brain Lower Grade Glioma	0.0695	0.0433	1.7e-07	0.065	0.055	0.054	NA	0.060	7.1e-08	6.2e-07	9.8e-07	NA	2.0e-07
15	TCGA	Prostate Adenocarcinoma	0.0855	0.0427	6.8e-04	0.001	0.008	0.006	NA	0.003	2.2e-01	3.9e-02	6.2e-02	NA	1.5e-01
16	TCGA	Thyroid Carcinoma	0.0200	0.0130	3.8e-03	0.027	0.026	0.023	NA	0.025	1.0e-03	1.4e-03	2.2e-03	NA	1.7e-03
17	TCGA	Uterine Corpus Endometrial Carcinoma	0.1740	0.0900	1.1e-03	0.052	0.072	0.035	NA	0.050	1.5e-02	4.8e-03	3.7e-02	NA	1.6e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	0.5	0.8	2.6	-0.2	0.7	0.1	1.1	0.1	0.4	-0.0	-0.1	-0.9	1.6	1.5	-0.5	-1.4	-0.7	-1.4	0.4	-1.4
Bipolar Disorder or Schizophrenia	0.1	0.2	0.8	-0.2	-0.2	-0.2	0.3	0.7	-0.2	-0.2	-0.1	0.4	0.9	0.9	-0.4	-0.9	0.7	-0.1	-0.2	-0.6
Depressed Affect (Nagel 2018)	1.9	4.0	8.4	2.3	0.9	1.9	-0.4	2.8	1.9	1.9	1.4	-1.6	-2.7	-2.9	2.6	2.9	-1.6	1.6	1.7	0.9
Depression (Nagel 2018)	1.2	1.9	4.7	1.4	0.7	1.2	-0.4	2.1	1.1	1.3	0.9	-0.3	-1.9	-2.1	1.8	2.2	-0.7	1.2	0.9	0.8
Intelligence (Savage-Jansen 2018)	5.4	16.7	27.7	-4.8	-3.3	-5.2	-3.9	-3.8	-5.0	-5.1	-5.3	4.0	-0.1	0.1	-4.9	-3.5	4.4	-2.0	-5.2	3.5
Neuroticism (Nagel 2018)	1.5	3.6	9.9	2.0	0.2	1.6	-0.8	2.3	1.4	1.6	1.2	-1.1	-3.0	-3.2	2.4	2.9	-0.8	2.1	1.3	1.2
Schizophrenia (2018)	0.2	0.4	2.0	-0.1	-0.8	-0.4	-0.5	0.4	-0.5	-0.2	-0.1	1.2	-0.1	-0.1	-0.2	-0.0	1.4	1.0	-0.6	0.4
Schizophrenia vs Biploar Disorder	1.2	1.6	4.1	2.0	0.5	1.5	0.9	0.6	1.4	1.7	1.9	-0.5	-0.3	-0.5	1.8	1.7	-0.7	0.7	1.4	-0.8
Worry (Nagel 2018)	1.7	3.5	8.6	2.4	-1.1	1.9	-0.4	0.3	1.7	2.0	1.7	-1.6	-2.6	-2.7	2.6	2.9	-1.2	1.9	1.7	0.7
Alzheimer’s Disease (in mother)	1.4	1.7	12.1	-0.4	-0.2	-0.1	-1.3	0.4	-0.7	-0.2	0.2	1.9	-1.7	-1.6	0.3	1.5	1.1	3.5	-0.3	1.2
Alzheimer’s Disease (in father)	0.8	0.9	3.4	-0.3	0.3	-0.5	1.0	-0.3	-0.4	-0.5	-0.5	-0.3	1.7	1.8	-1.1	-1.5	-0.2	-1.2	-0.1	-1.3
Alzheimer’s Disease (including proxy)	0.6	0.8	3.9	-0.0	0.6	0.8	1.0	1.8	0.4	0.9	1.0	0.5	0.1	0.2	0.1	0.7	-0.7	2.0	0.9	-1.0
Crohns Disease (2017)	0.6	1.3	2.7	-1.0	-1.2	-1.5	-1.6	-0.2	-1.4	-1.4	-1.7	0.8	-0.8	-0.7	-1.0	-0.9	0.8	0.4	-1.3	1.3
Irritable Bowel Disease (IBD)	0.6	1.5	3.4	1.8	-0.5	1.4	0.6	1.2	1.3	1.4	1.4	-1.2	-0.7	-0.6	1.7	1.3	-1.3	0.9	1.5	-0.7
Ulcerative Colitis (UC)	3.2	6.1	11.7	3.4	0.1	3.2	1.9	1.6	2.9	3.1	3.4	-2.2	-0.6	-0.5	3.3	2.6	-2.4	1.3	3.3	-2.1
Major Depression (MDD)	0.3	0.3	1.9	0.0	0.9	0.0	0.3	0.0	0.5	0.3	0.2	-1.1	0.1	0.1	0.3	-0.2	-0.8	-1.4	0.4	-0.4
Reaction Time	3.5	6.6	11.2	-2.9	-2.3	-3.0	-3.3	0.2	-3.2	-2.9	-3.0	3.1	-2.0	-1.7	-2.4	-1.0	3.0	1.0	-3.0	2.8
Verbal and Numeric Reasoning (VNR)	4.4	10.7	18.5	-3.8	-2.9	-4.2	-3.2	-2.4	-3.9	-4.0	-4.3	3.0	-0.2	-0.1	-3.9	-3.0	3.6	-1.5	-4.1	3.0
Breast Cancer	4.3	10.4	20.9	4.3	1.4	4.1	2.7	-1.9	4.1	3.9	4.6	-3.7	-0.4	-0.6	4.1	3.1	-3.9	0.2	4.1	-2.2
Ovarian Cancer	0.9	1.2	3.4	-0.1	-1.5	-0.1	-1.3	-0.8	-0.4	-0.1	-0.1	0.6	-1.6	-1.7	0.4	1.9	0.8	1.4	-0.3	1.7
Prostate Cancer	3.3	4.6	7.7	-2.6	-2.2	-2.6	-2.2	-0.5	-2.7	-2.8	-2.7	2.4	-0.1	-0.1	-2.6	-2.1	2.4	-0.1	-2.6	1.8
Age at First Birth	0.6	0.8	2.4	-0.8	-0.9	-1.0	-0.4	-1.2	-1.2	-1.1	-0.8	1.6	0.6	0.5	-1.0	-1.0	0.8	0.3	-1.0	0.4
Bipolar Disorder (2011)	0.4	0.3	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.2	-1.0	1.2	-0.3	-1.3	0.5
Body Mass Index (BMI) (2010)	0.3	0.5	1.4	-0.4	0.8	-0.4	0.5	-1.0	-0.2	-0.5	0.1	0.0	1.1	1.2	-0.7	-1.1	-0.1	-0.6	-0.2	-0.6
Coronary Artery Disease (CAD)	1.2	1.5	6.2	0.5	-1.0	1.0	-0.3	-2.5	0.9	1.0	0.8	-0.6	-1.8	-1.9	1.4	1.8	-0.5	0.7	0.8	0.6
Crohns Disease (2012)	0.9	1.4	3.2	-1.1	-1.3	-1.3	-1.8	-0.0	-1.2	-1.3	-1.7	0.8	-1.2	-1.2	-0.9	-0.4	0.8	0.3	-1.3	1.7
Mean Putamen Volume	1.9	2.2	7.1	-2.0	0.2	-1.8	-0.5	0.4	-1.7	-1.9	-1.7	1.5	1.2	1.4	-2.2	-2.7	0.9	-0.2	-1.4	0.0
Fasting Glucose	0.3	0.4	1.7	-0.1	-0.6	-0.3	0.5	1.3	-0.3	-0.3	-0.1	0.3	1.1	1.0	-0.6	-0.4	0.1	-0.7	-0.0	-0.6
HbA1C	0.4	0.4	2.8	-0.6	0.2	-0.6	-0.4	-0.4	-0.7	-0.6	-0.6	1.7	0.2	0.1	-0.5	-0.1	1.1	0.5	-0.7	0.3
HDL Cholesterol	0.4	0.6	2.0	-0.4	0.8	-0.0	-0.9	-1.4	-0.2	0.1	0.4	-0.4	-1.3	-1.3	0.4	0.9	-0.4	1.2	0.2	0.8
LDL Cholesterol	1.9	3.0	6.0	-1.4	-1.2	-1.6	-2.4	-0.3	-2.0	-1.5	-2.1	2.1	-1.8	-1.6	-1.1	-0.3	2.3	1.7	-1.9	2.3
Lupus	0.3	0.5	2.0	-0.3	0.8	-0.3	0.4	0.7	-0.2	-0.4	-0.3	0.7	1.1	1.1	-0.7	-1.4	0.4	-0.4	-0.4	-0.7
Neuroticism (2016)	1.3	1.8	5.8	-0.6	-1.7	-0.8	-1.8	-0.3	-1.0	-0.2	-0.7	1.3	-2.4	-2.4	0.1	0.8	0.8	2.1	-0.5	1.7
Primary Biliary Cirrhosis	0.0	0.0	0.0	-0.1	0.1	0.1	-0.1	-0.1	0.2	0.2	0.0	0.1	0.0	-0.1	0.1	0.1	0.0	-0.0	0.0	0.0
Rheumatoid Arthritis	0.4	0.5	2.6	-0.6	-0.3	-0.8	-0.7	-1.6	-0.6	-0.8	-0.7	0.3	-0.4	-0.3	-0.6	-0.4	0.5	-0.7	-0.7	0.8
Schizophrenia (2014)	0.2	0.4	0.9	0.9	-0.4	0.4	0.9	0.6	0.4	0.7	0.7	0.4	0.8	0.9	0.3	-0.1	0.2	0.3	0.4	-0.9
Triglycerides	0.3	0.5	1.8	0.4	0.1	0.3	1.1	1.2	0.2	0.4	-0.1	0.4	1.3	1.3	-0.0	-0.7	0.3	-0.4	0.3	-1.2
Type 2 Diabetes (T2D) (2012)	1.3	1.5	2.6	-1.4	-0.9	-1.4	-1.5	1.0	-1.6	-1.4	-1.5	1.2	-0.6	-0.6	-1.2	-0.6	1.4	0.4	-1.5	1.2
Ulcerative Colitis	1.9	2.7	5.7	2.4	-0.6	2.2	1.6	0.4	1.9	2.2	2.4	-1.1	0.3	0.2	2.1	1.7	-1.2	1.0	2.1	-1.6
Blood Eosinophil Count	0.2	1.3	5.6	0.2	1.2	0.4	0.6	2.4	-0.1	0.4	1.0	1.5	1.1	1.1	0.0	-0.2	1.4	1.9	0.1	-1.4
Blood Platelet Count	1.4	16.6	45.7	1.7	3.5	1.7	5.8	2.2	2.9	1.7	2.8	-2.6	6.7	6.6	-0.1	-3.5	-2.7	-6.8	2.5	-6.3
Blood Red Count	2.4	23.5	45.8	5.4	4.8	4.9	6.8	3.8	5.4	5.3	4.7	-5.3	4.4	4.4	3.7	0.5	-5.4	-2.7	5.4	-6.2
Blood White Count	0.7	5.3	9.4	2.8	2.2	2.8	2.6	1.7	2.8	2.8	3.1	-1.7	1.1	0.9	2.3	1.5	-2.4	0.2	3.0	-3.0
Heel T-Score	4.6	36.7	73.8	7.1	5.2	7.0	6.3	3.7	7.2	7.1	6.6	-8.6	1.1	1.3	6.3	4.0	-8.4	0.1	7.8	-5.8
BMI	2.9	16.6	30.7	4.5	4.2	5.1	4.5	1.3	5.0	5.0	5.5	-3.9	1.2	1.0	4.5	2.3	-4.9	0.5	5.3	-4.5
Height	2.0	38.1	70.9	-5.5	-8.1	-5.8	-8.3	-5.7	-6.1	-6.1	-5.7	7.1	-5.1	-5.0	-4.2	-0.7	8.2	0.4	-7.3	8.4
Waist Hip Ratio (WHR)	2.2	9.7	22.8	3.4	-1.1	3.4	-0.1	1.7	3.0	3.4	2.9	-2.7	-3.6	-3.7	4.3	4.8	-2.8	3.7	3.5	0.2
Systolic Blood Pressure	3.7	18.6	34.8	5.5	0.5	5.4	2.3	0.8	5.2	5.4	4.9	-5.3	-2.6	-2.8	5.9	5.3	-5.0	1.7	5.7	-2.3
Smoking Status	4.6	11.0	18.3	-4.0	-1.4	-4.1	-4.1	0.3	-4.2	-4.0	-4.3	4.0	-1.5	-1.5	-3.5	-2.3	3.7	1.4	-4.1	3.6
Allergy or Eczema	0.6	1.6	6.0	-0.2	-1.4	-0.2	-1.6	-1.9	-0.7	-0.2	-0.2	1.1	-1.9	-1.9	0.3	1.2	0.8	2.4	-0.4	1.5
Cardiovascular Disease	1.3	4.2	7.7	2.6	-0.4	2.5	0.9	0.7	2.3	2.5	2.1	-2.6	-1.3	-1.3	2.8	2.7	-2.6	1.0	2.7	-0.9
Hypothyroidism (self reported)	1.7	3.9	15.3	1.9	-1.1	1.6	-0.7	0.4	1.0	1.8	1.7	0.1	-2.6	-2.8	2.5	3.5	-0.5	3.9	1.3	1.1
Respiratory disease	0.3	0.8	2.7	-0.3	0.0	0.1	-1.0	-0.1	-0.2	0.1	-0.3	1.0	-1.6	-1.6	0.5	0.9	1.1	1.3	-0.5	1.2
Type 2 Diabetes (T2D) (2018)	0.5	0.8	1.6	-0.9	-1.3	-0.8	-1.2	0.1	-1.0	-0.9	-1.3	0.7	-0.8	-0.7	-0.6	0.1	0.6	1.2	-0.9	1.3
Lung FEV1/FVC ratio	2.0	10.1	20.2	4.1	2.0	4.1	1.9	-0.3	3.9	4.1	4.5	-2.7	-0.9	-1.4	4.4	3.5	-3.1	1.6	4.3	-2.2
Lung FVC	2.2	11.1	21.1	-4.4	-1.5	-4.4	-3.5	-2.3	-4.2	-4.4	-4.6	2.6	-0.7	-0.6	-4.0	-3.4	2.8	0.2	-4.1	3.3
Neuroticism	0.9	2.1	9.1	0.2	0.1	-0.1	-1.8	3.0	0.1	-0.1	-0.4	-0.6	-2.8	-2.9	0.7	1.3	-0.2	0.7	-0.1	2.0
Chronotype (morning person)	0.4	0.8	2.4	1.0	0.1	0.9	-0.0	-1.3	0.6	1.0	1.0	-0.6	-1.0	-0.9	1.2	1.3	-0.4	1.6	0.7	0.2
Hair Pigment	0.0	0.5	2.7	-1.1	-0.3	-0.8	0.2	-1.6	-0.9	-0.7	-0.1	0.8	0.1	0.2	-0.7	-0.4	0.0	1.4	-0.1	-0.1
Tanning	0.6	7.0	14.7	-2.5	-2.9	-2.5	-3.7	-1.3	-3.0	-2.7	-1.9	3.4	-2.2	-2.2	-1.9	0.7	3.8	1.8	-3.0	3.4
Hand grip strength (left)	2.9	7.7	15.0	3.6	0.9	3.7	2.6	1.4	3.4	3.7	3.9	-2.7	0.3	0.1	3.6	3.4	-2.3	0.6	3.4	-2.3
Number of treatments/medications taken	2.0	3.6	13.5	0.9	-1.3	1.0	-1.6	1.1	0.2	0.9	0.5	0.7	-3.2	-3.2	1.8	3.3	0.2	3.7	0.4	1.9
Average weekly spirits intake	1.0	1.2	5.0	-1.3	-0.6	-1.4	-1.1	-2.2	-1.2	-1.4	-1.0	1.2	-0.4	-0.3	-1.3	-0.9	0.8	-0.4	-0.8	0.5
Sensitivity / hurt feelings	0.6	1.1	4.1	-0.2	-1.1	-0.3	-1.6	0.9	-0.0	-0.4	-0.9	-0.0	-1.9	-2.0	0.2	0.3	0.4	-0.4	-0.7	1.9
Frequency of depressed mood in last 2 weeks	1.0	1.4	5.3	0.2	0.1	-0.3	-1.5	2.2	-0.3	-0.1	-0.6	0.1	-2.3	-2.3	0.5	1.2	-0.1	1.0	-0.2	1.8
Hearing difficulty/problems: Yes	0.7	1.1	11.7	-0.2	0.2	-0.4	-0.0	1.1	0.2	-0.2	-1.2	-1.3	0.2	0.0	-0.3	-0.6	-1.0	-3.4	-0.3	0.9
Relative age of first facial hair	2.0	4.1	7.8	-2.2	-0.3	-1.9	0.2	-1.6	-1.7	-1.9	-1.3	2.5	2.8	2.8	-2.6	-2.6	2.3	-2.4	-2.0	-0.7
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.6	0.5	0.4	0.5	0.1	0.8	0.3	0.5	0.6	-0.1	-0.0	0.0	0.4	0.4	-0.2	0.7	0.4	-0.1
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.2	0.9	0.4	1.0	0.2	-1.0	0.9	1.0	0.8	-0.4	-0.7	-0.6	1.1	0.4	-0.7	0.7	0.8	-0.1
Ever had hysterectomy (womb removed)	0.7	0.8	3.3	0.1	-1.0	0.1	-1.2	-0.9	-0.0	0.1	0.3	-0.0	-1.8	-1.8	0.7	1.0	0.3	0.8	-0.1	1.3
Systolic blood pressure, automated reading	3.2	9.3	17.6	3.9	0.1	3.9	1.8	-0.7	3.7	3.9	3.6	-3.2	-1.8	-1.7	4.2	3.5	-3.6	1.4	4.1	-1.9
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.3	-0.5	-0.2	-0.7	-1.1	0.0	-0.8	-0.6	-0.8	0.8	-1.1	-1.0	-0.3	0.1	0.9	0.7	-0.7	1.1
Angina	0.3	0.4	1.0	-0.5	-1.0	-0.6	-0.5	0.7	-0.5	-0.6	-0.7	0.3	0.0	-0.1	-0.6	-0.6	0.5	-0.9	-0.9	0.8
Medication for hormone replacement therapy	0.6	0.7	4.5	0.1	-0.4	-0.1	0.7	-0.6	0.2	-0.1	-0.0	-0.4	1.1	1.2	-0.5	-1.1	-0.4	-2.1	0.0	-0.9
Vitamin and mineral supplements	0.2	0.3	0.7	-0.6	0.8	-0.5	-0.5	0.8	-0.4	-0.5	-0.6	0.8	-0.1	-0.1	-0.5	-0.4	0.4	0.4	-0.6	0.7
Supplements: Zinc	0.3	0.3	1.2	0.3	-0.2	0.3	0.9	-0.2	0.4	0.3	0.2	-0.8	1.1	0.9	0.0	-0.5	-0.4	-1.0	0.1	-0.6
Medication: Co-codamol	0.2	0.2	1.8	-0.4	-0.1	-0.6	-0.0	-1.3	-0.6	-0.5	-0.2	0.2	0.2	0.5	-0.6	-0.5	-0.1	0.3	-0.1	-0.1
Medication: Metformin	0.7	1.0	3.1	-1.0	-0.8	-1.3	-0.6	-0.3	-1.2	-1.3	-1.7	0.1	0.4	0.5	-1.4	-1.4	0.4	-0.9	-1.2	0.7
Diabetes (father)	2.8	3.5	7.0	-1.8	-2.4	-2.5	-2.1	0.3	-2.5	-2.5	-2.6	1.4	-1.0	-0.7	-2.2	-1.0	1.6	0.1	-2.2	1.9
Diabetes (mother)	1.8	2.3	7.1	0.7	2.2	0.7	2.1	1.8	1.0	0.8	0.5	-1.1	2.3	2.3	0.1	-0.7	-0.6	-2.7	0.6	-1.9
Severe depression (siblings)	0.9	1.0	3.1	-1.2	0.3	-1.5	-0.7	-1.3	-1.2	-1.4	-1.2	0.4	0.2	0.3	-1.4	-1.8	0.4	-0.6	-0.9	0.3
Pack years adult smoking proportion	0.6	0.9	1.8	1.1	0.4	0.9	1.3	-0.2	1.0	0.8	1.0	-0.5	1.2	1.1	0.5	-0.4	-0.9	-1.4	0.8	-1.3
Impedance of leg (right)	1.0	4.6	15.6	1.2	-1.8	0.9	-1.8	-2.2	0.5	1.0	0.9	-0.3	-4.0	-3.9	2.0	3.7	-0.1	3.2	1.0	1.7
Leg fat-free mass (left)	0.2	0.9	3.3	0.4	0.6	0.6	1.2	0.5	0.8	0.5	1.1	-0.1	1.5	1.5	0.1	-0.9	-0.5	-1.8	0.4	-1.2
Trunk fat percentage	1.4	5.6	14.7	2.6	1.9	2.9	2.3	-1.9	2.8	2.8	3.8	-1.4	0.2	0.3	2.7	1.3	-2.9	0.7	3.2	-2.7
Hand grip strength (right)	1.8	4.9	9.0	2.8	-0.5	2.8	2.2	0.8	2.8	2.8	2.9	-3.0	0.4	0.3	2.6	2.2	-2.1	-0.6	2.7	-2.0
Townsend deprivation index at recruitment	1.4	2.0	4.4	-2.1	0.3	-2.1	-1.3	0.1	-1.8	-2.0	-1.8	1.3	-0.1	0.0	-1.9	-2.0	1.1	-0.5	-1.4	0.4
Current tobacco smoking	2.0	3.2	5.7	-1.6	-1.6	-2.3	-1.6	-0.4	-2.2	-2.2	-2.1	2.4	0.3	0.2	-2.3	-1.8	2.2	-0.7	-2.4	1.3
Average weekly fortified wine intake	0.9	1.1	8.0	0.9	-0.4	1.0	0.8	-2.8	0.9	0.8	1.2	-0.7	0.8	0.6	0.7	0.2	-0.5	-0.1	0.9	-1.1
Maternal smoking around birth	3.8	5.5	11.6	-3.4	-1.0	-3.1	-2.0	1.1	-3.0	-3.0	-3.3	2.5	0.0	0.1	-3.0	-2.1	2.5	-0.5	-2.9	1.6
Fed-up feelings	0.7	1.3	12.2	0.7	0.3	0.4	-0.3	3.5	0.6	0.4	0.2	-1.0	-1.4	-1.3	0.8	0.9	-1.2	0.5	0.6	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	6.8	1.2	1.8	1.1	0.6	2.6	1.0	1.1	1.1	0.5	-0.0	-0.2	1.1	1.0	-0.3	0.3	0.8	-0.4
Relative age voice broke	0.3	0.5	1.3	0.2	1.1	0.6	1.1	-0.4	0.7	0.5	0.6	0.6	1.1	1.1	0.2	-0.2	0.2	-0.8	0.4	-1.1
Taking other prescription medications	1.0	1.6	5.3	0.8	-1.0	0.6	-1.2	-0.0	0.2	0.6	0.3	0.2	-2.3	-2.3	1.2	2.3	0.3	2.0	0.2	1.5
Age when periods started (menarche)	1.6	3.9	6.7	-2.2	-0.2	-2.2	-2.4	0.4	-2.6	-2.1	-2.5	2.2	-1.2	-1.0	-1.9	-0.4	2.2	2.4	-2.3	2.5
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.8	-0.6	-0.4	-0.6	-1.2	-1.7	-0.5	-0.6	-0.7	0.4	-1.1	-1.2	-0.2	-0.4	0.8	-0.2	-0.8	1.1
Heel bone mineral density (BMD) T-score, automated (left)	3.8	8.7	19.5	3.4	2.0	3.5	2.6	2.1	3.8	3.5	2.9	-4.2	-0.3	-0.4	3.5	2.3	-4.4	-0.8	3.8	-2.1
Tinnitus: Yes, but not now, but have in the past	1.0	1.0	2.4	1.4	0.7	1.4	0.5	1.0	1.1	1.4	1.3	0.1	-0.3	-0.6	1.6	1.3	0.1	1.1	0.9	-0.5
Qualifications: CSEs or equivalent	0.2	0.2	0.7	-0.1	-0.5	-0.2	-0.6	0.6	-0.3	-0.3	-0.5	0.8	-0.4	-0.5	-0.1	0.2	0.9	0.2	-0.6	0.8
Serious illness, injury or assault to yourself	0.7	0.9	3.9	0.2	-0.4	0.3	-0.8	1.5	0.1	0.2	0.1	-0.3	-1.6	-1.5	0.6	1.2	-0.2	2.0	0.2	1.1
High blood pressure	0.5	1.3	2.3	1.2	-1.4	1.3	-0.1	-0.2	1.1	1.3	1.0	-1.0	-1.2	-1.2	1.5	1.5	-1.3	1.3	1.4	-0.1
Hayfever, allergic rhinitis or eczema	0.2	0.5	3.5	-0.2	-0.7	-0.3	-0.8	-1.9	-0.4	-0.2	-0.0	-0.3	-0.9	-1.0	0.1	0.6	0.1	1.1	-0.1	0.8
Multivitamins +/- minerals	0.3	0.4	0.8	0.5	-0.8	0.7	0.1	-0.8	0.6	0.6	0.7	-0.7	-0.6	-0.7	0.8	0.9	-0.4	0.3	0.7	-0.3
Stomach or abdominal pain in last month	0.1	0.1	0.9	-0.3	0.9	-0.3	0.1	0.6	-0.1	-0.3	0.1	0.2	0.3	0.5	-0.4	-0.4	-0.1	-0.3	0.0	-0.4
Supplements: Glucosamine	1.5	1.9	3.8	1.8	-0.5	1.9	1.1	-0.5	1.6	1.8	1.9	-1.3	0.1	-0.1	1.8	1.7	-1.4	1.4	1.6	-0.8
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.5	1.1	0.5	0.8	0.7	-0.5	0.9	0.9	1.2	0.0	0.0	-0.2	0.9	0.6	-0.3	-0.3	0.8	-0.5
Medication: Atenolol	0.3	0.4	1.9	0.7	0.1	0.5	-0.4	0.2	0.3	0.5	0.4	0.3	-0.6	-0.7	0.7	1.2	0.3	1.4	0.1	0.7
Medication: Levothyroxine sodium	0.8	1.4	6.6	0.2	-1.5	0.0	-1.4	0.3	-0.4	0.1	-0.1	1.3	-1.6	-1.8	0.6	1.3	1.2	2.6	-0.4	1.5
Sitting height	3.0	21.0	40.4	-4.7	-5.4	-4.9	-6.1	-2.1	-5.1	-5.0	-4.9	4.9	-3.4	-3.2	-3.7	-1.0	5.6	0.9	-5.7	6.4
Chronic bronchitis/emphysema (father)	0.3	0.4	0.9	-0.5	-0.5	-0.5	-0.6	0.2	-0.6	-0.5	-1.0	0.4	-0.1	-0.2	-0.4	-0.5	0.9	0.8	-0.9	0.9
High blood pressure (mother)	1.1	1.5	4.5	1.3	-1.5	1.1	-0.2	1.1	0.8	1.2	0.7	-1.2	-1.7	-1.6	1.6	2.1	-0.9	0.8	1.1	0.3
Body mass index (BMI)	1.5	6.4	11.9	2.5	2.8	2.9	3.2	0.6	3.1	2.8	3.3	-2.3	1.4	1.4	2.3	0.3	-3.5	-0.6	3.2	-3.3
Impedance of leg (left)	1.0	4.7	15.2	1.1	-1.9	0.8	-1.9	-2.6	0.3	0.8	0.7	0.3	-3.9	-3.8	1.9	3.5	0.3	3.4	0.7	2.0
Leg predicted mass (left)	0.2	0.8	3.1	0.4	0.6	0.6	1.2	0.4	0.8	0.5	1.1	-0.1	1.4	1.4	0.2	-0.8	-0.5	-1.8	0.4	-1.2
Trunk fat mass	1.0	4.2	11.5	2.3	1.5	2.5	1.9	-1.7	2.6	2.4	3.4	-1.2	0.1	0.2	2.4	1.0	-2.5	0.2	2.7	-2.2
Waist circumference	1.5	5.6	11.3	2.9	1.7	3.1	2.5	0.5	3.0	3.0	3.4	-1.9	0.4	0.5	2.8	1.3	-2.9	0.3	3.2	-2.5
Number of incorrect matches in round	4.2	7.0	12.8	3.6	2.9	3.3	2.9	0.7	3.3	3.4	3.4	-2.2	1.0	0.6	3.1	2.2	-2.4	-0.3	3.2	-2.5
Past tobacco smoking	4.3	7.8	14.6	3.4	0.5	3.1	3.5	0.4	3.6	3.1	3.1	-3.8	1.8	1.5	2.6	1.3	-3.5	-2.5	3.2	-3.0
Alcohol usually taken with meals	0.4	0.7	1.7	0.9	1.3	1.1	0.7	0.0	1.1	1.1	1.2	-0.2	0.3	0.1	1.0	0.4	-0.8	0.1	1.0	-0.6
Nervous feelings	2.1	4.0	11.1	2.7	-1.7	2.0	-0.2	0.4	1.7	2.1	1.7	-1.7	-2.4	-2.6	2.7	3.3	-1.5	1.9	1.8	0.7
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.4	4.1	2.0	1.7	1.9	1.0	1.6	1.8	2.0	1.9	-1.2	-0.4	-0.5	2.0	1.9	-1.3	0.9	1.7	-0.7
Hearing difficulty/problems with background noise	1.8	2.8	17.5	-0.2	1.8	-0.1	1.7	1.6	0.6	0.0	-0.3	-1.1	2.7	2.4	-0.7	-2.0	-0.8	-4.2	-0.0	-1.3
Hair/balding pattern: Pattern 2	0.9	1.2	4.4	-0.7	1.4	-0.9	0.6	-0.5	-0.8	-0.7	-0.6	0.4	1.9	2.1	-1.3	-1.7	0.8	-0.6	-0.9	-0.7
Had menopause	0.5	0.6	5.0	-0.1	0.7	-0.1	-0.4	-0.2	-0.6	-0.1	0.1	1.6	-0.2	-0.2	-0.0	0.4	1.1	2.2	-0.5	0.5
Had other major operations	0.5	0.6	2.6	0.2	1.2	0.1	-0.2	1.5	-0.2	0.2	-0.2	1.6	0.0	-0.0	0.2	0.4	1.1	1.3	-0.5	0.6
Forced vital capacity (FVC)	2.0	7.8	12.6	-3.4	-2.7	-3.5	-2.9	-1.9	-3.3	-3.5	-3.4	2.9	-0.7	-0.6	-3.1	-2.3	3.1	-0.7	-3.5	2.7
Heel bone mineral density (BMD) T-score, automated (right)	3.7	8.4	20.6	3.2	2.1	3.2	2.8	2.9	3.6	3.2	2.6	-4.5	0.0	0.1	3.0	1.8	-4.5	-1.4	3.6	-2.2
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.0	1.4	1.0	1.2	0.9	1.3	1.2	1.3	1.3	-1.0	-0.1	-0.2	1.3	0.7	-1.3	0.2	1.3	-0.7
Qualifications: None of the above	0.4	0.8	2.5	0.9	0.7	0.9	-0.2	-0.2	1.0	0.7	1.0	-0.7	-1.4	-1.6	1.2	0.9	-0.9	0.4	1.0	-0.1
Financial difficulties in last 2 years	0.7	0.9	1.7	-1.3	-0.5	-1.3	-1.0	-0.0	-1.1	-1.3	-1.2	0.8	-0.4	-0.2	-1.2	-0.9	1.0	-1.0	-1.2	0.8
Mouth/teeth dental problems	0.5	0.8	6.3	0.5	0.3	0.4	0.3	-2.5	0.6	0.4	0.4	-1.6	-0.4	-0.6	0.6	0.6	-1.4	-0.8	0.6	0.1
Heart attack	0.7	0.8	1.6	-1.1	1.1	-1.3	-0.8	-0.1	-1.1	-1.2	-1.1	0.2	0.0	0.1	-1.2	-1.0	0.5	-0.5	-1.2	1.1
Allergy	0.1	0.3	1.8	0.0	0.1	-0.2	0.3	1.4	-0.1	-0.2	-0.2	-0.2	0.7	0.8	-0.4	-0.6	-0.3	-0.7	-0.0	-0.4
Pain all over the body in last month	0.7	0.8	2.7	-0.8	-0.0	-1.0	-1.5	-0.4	-0.8	-0.9	-1.0	0.1	-1.6	-1.4	-0.5	-0.5	-0.0	-0.0	-0.6	1.2
Diabetes (self-reported)	1.1	1.8	4.8	-1.6	-0.9	-1.7	-1.6	-0.9	-1.7	-1.6	-2.2	0.6	-0.7	-0.5	-1.5	-1.0	0.9	0.4	-1.6	1.5
Hayfever/allergic rhinitis (self-reported)	2.1	2.8	4.6	-1.6	-2.1	-1.8	-2.0	0.2	-2.1	-1.8	-2.1	1.9	-1.2	-0.9	-1.5	-0.2	1.9	1.1	-2.0	2.1
Medication: Ramipril	0.6	0.8	5.7	0.4	-2.4	0.4	-0.6	-0.5	0.4	0.4	0.3	-0.4	-1.2	-1.4	0.8	0.9	-0.8	0.4	0.5	0.7
Medication: Simvastatin	0.3	0.5	2.0	0.4	-1.1	0.1	-0.9	-0.6	0.1	-0.0	-0.2	-0.2	-1.3	-1.4	0.4	0.5	-0.4	0.4	0.2	0.6
Fluid intelligence score	4.9	10.2	17.2	-3.8	-2.6	-4.1	-2.6	-2.1	-3.9	-4.0	-4.0	3.2	0.5	0.5	-4.0	-3.0	3.7	-2.5	-4.0	2.3
Illnesses of siblings	0.1	0.1	1.2	0.3	1.1	0.2	-0.2	0.3	-0.0	0.1	0.2	-0.2	-0.4	-0.4	0.2	0.5	0.1	0.3	0.0	0.2
Neuroticism score	1.1	2.3	8.0	1.2	-0.4	0.8	-1.2	2.6	0.9	0.9	0.4	-1.2	-2.7	-2.8	1.6	1.9	-1.0	0.7	0.8	1.4
Weight	0.3	1.6	4.8	1.5	0.5	1.7	1.1	-0.8	1.7	1.6	2.2	-0.6	-0.1	-0.0	1.6	0.6	-1.4	-0.4	1.6	-1.1
Impedance of arm (right)	0.3	1.5	12.1	-0.5	-1.2	-0.8	-1.2	-3.5	-1.0	-0.8	0.1	1.5	-1.0	-0.9	-0.4	0.4	1.1	1.3	-0.5	0.5
Arm fat percentage (right)	1.9	7.5	15.4	2.7	3.0	3.0	3.4	-0.7	3.1	2.9	3.9	-2.2	1.5	1.6	2.4	0.4	-3.6	-0.2	3.6	-3.9
Trunk fat-free mass	0.1	0.3	1.7	-0.1	-1.0	-0.2	-0.6	0.3	-0.1	-0.3	-0.2	0.2	-0.3	-0.4	-0.1	-0.1	0.6	-1.3	-0.7	0.9
Hip circumference	0.4	1.9	3.8	1.2	1.2	1.3	1.9	-0.9	1.5	1.3	1.9	-0.5	1.4	1.5	0.9	-0.6	-1.4	-1.4	1.3	-2.0
Time employed in main current job	0.4	0.5	1.1	0.9	0.5	0.8	0.9	-0.4	0.8	0.8	1.0	-0.4	0.6	0.5	0.6	0.3	-0.5	0.3	0.9	-1.0
Alcohol intake versus 10 years previously	0.9	1.3	2.4	1.4	-0.3	1.3	1.1	-0.1	1.5	1.2	1.2	-1.5	0.2	0.2	1.2	0.3	-1.5	-1.2	1.5	-1.5
Father’s age at death	0.2	0.2	0.7	0.1	-0.6	-0.1	-0.5	-0.8	-0.3	-0.1	-0.3	0.7	-0.6	-0.8	0.1	0.2	0.5	0.9	-0.3	0.4
Worrier / anxious feelings	0.9	1.6	4.3	1.4	-1.1	1.1	-0.6	-0.9	1.1	1.1	0.8	-1.0	-2.1	-2.1	1.6	1.9	-0.8	0.9	0.9	0.9
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.4	10.5	2.3	2.2	1.9	0.7	3.2	1.7	1.9	1.6	-1.1	-1.2	-1.0	2.1	1.9	-2.0	2.1	1.9	-0.2
Falls in the last year	0.3	0.4	1.5	0.1	0.3	0.3	0.7	-0.5	0.5	0.4	0.8	-0.1	0.5	0.5	0.2	-0.4	-0.8	-1.2	0.7	-1.2
Hair/balding pattern: Pattern 3	0.9	1.3	2.9	-0.6	-0.6	-0.5	-1.6	-1.2	-0.7	-0.7	-0.9	1.7	-1.6	-1.7	-0.1	0.8	1.1	1.4	-0.8	1.7
Number of live births	0.6	0.8	2.2	-1.1	1.2	-0.7	-1.0	-0.8	-0.9	-0.7	-0.7	0.9	-1.0	-0.8	-0.5	-0.3	0.9	1.5	-0.8	1.1
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	3.7	-1.7	-1.4	-1.9	-1.6	-1.5	-1.7	-1.9	-1.8	1.6	-0.4	-0.4	-1.6	-1.2	1.7	-0.7	-1.9	1.5
Pulse rate	2.3	4.0	6.6	2.0	1.6	2.4	2.0	2.3	2.5	2.4	2.5	-2.1	0.4	0.4	2.2	1.5	-2.2	0.2	2.6	-2.1
Happiness	3.2	3.8	12.2	2.3	-0.2	2.1	0.5	1.8	1.6	2.3	1.9	-0.9	-1.8	-1.8	2.7	3.5	-1.4	2.9	1.9	0.3
Noisy workplace	2.0	2.5	4.3	2.1	1.5	1.9	1.9	1.0	1.9	2.0	1.9	-0.9	0.9	0.7	1.7	0.9	-1.8	-0.1	2.0	-1.7
Qualifications: A levels/AS levels or equivalent	0.8	1.8	4.7	-1.5	-2.0	-1.3	-1.0	-0.1	-1.7	-1.3	-1.0	2.2	0.4	0.4	-1.3	-0.2	2.0	0.9	-1.6	1.0
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	3.2	-1.1	-1.4	-0.8	-1.7	-0.7	-1.0	-0.7	-1.0	1.5	-1.8	-1.8	-0.2	0.5	0.8	1.8	-0.7	1.6
Mouth/teeth dental problems: Dentures	1.2	2.0	6.1	-1.5	-0.1	-1.6	-1.6	-0.2	-1.7	-1.5	-1.5	2.5	-0.6	-0.4	-1.4	-1.1	2.1	1.1	-1.7	1.2
Asthma	0.1	0.2	0.4	-0.6	0.5	-0.3	-0.4	0.6	-0.3	-0.3	-0.6	0.6	-0.6	-0.4	-0.2	-0.3	0.5	0.1	-0.5	0.4
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	3.7	1.4	-0.5	1.7	0.5	-0.2	1.4	1.4	1.1	-1.3	-1.0	-1.0	1.7	1.9	-1.2	0.0	1.3	-0.2
Medication: Cholesterol lowering	0.2	0.3	1.1	-0.6	-0.4	-0.4	-1.1	-0.2	-0.3	-0.5	-0.6	0.0	-1.0	-0.9	-0.2	0.1	0.1	-0.0	-0.4	0.9
Depression (self-reported)	0.9	1.1	2.7	-0.9	-1.3	-1.2	-1.3	1.6	-1.2	-1.2	-1.4	0.0	-1.0	-0.8	-0.9	-0.2	0.2	0.3	-0.9	1.3
Medication: Lansoprazole	0.2	0.2	0.6	0.0	0.5	-0.5	0.3	-0.2	-0.4	-0.4	-0.1	-0.1	0.7	0.8	-0.6	-0.8	-0.4	0.4	-0.1	-0.4
Prospective memory result	1.6	2.0	4.2	2.0	0.4	1.6	0.5	-0.0	1.5	1.7	1.3	-0.9	-1.4	-1.6	2.1	1.7	-1.4	1.6	1.7	-0.4
Lung cancer (father)	4.3	5.1	8.7	-2.1	-1.7	-2.3	-2.9	-1.4	-2.7	-2.3	-2.4	2.8	-1.7	-1.3	-1.9	-0.6	2.9	1.8	-2.8	3.0
Illnesses of mother	1.2	1.5	2.7	-1.5	-1.0	-1.6	-1.5	-0.9	-1.4	-1.7	-1.3	1.3	-0.6	-0.5	-1.4	-1.3	1.1	0.1	-1.4	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	2.9	-1.3	-0.6	-1.5	-1.4	-1.7	-1.2	-1.5	-1.5	0.5	-0.5	-0.6	-1.1	-0.9	1.0	-1.2	-1.5	1.5
Pulse wave Arterial Stiffness index	1.9	2.2	3.5	-1.8	-1.4	-1.8	-1.7	-0.8	-1.8	-1.8	-1.9	1.7	-0.3	-0.3	-1.6	-1.2	1.6	-0.3	-1.9	1.5
Impedance of arm (left)	0.4	1.8	9.8	-1.0	-1.4	-1.3	-1.2	-3.1	-1.4	-1.2	-0.3	2.1	-0.4	-0.2	-1.1	-0.2	1.8	0.9	-1.0	0.4
Arm fat mass (right)	1.3	5.4	12.1	2.5	2.3	2.7	2.5	-0.5	2.9	2.6	3.5	-1.9	0.7	0.7	2.4	0.7	-3.0	-0.4	3.1	-2.8
Trunk predicted mass	0.0	0.3	1.7	-0.1	-0.9	-0.1	-0.6	0.3	-0.0	-0.2	-0.2	0.1	-0.3	-0.3	-0.1	-0.1	0.6	-1.3	-0.6	0.9
Standing height	1.0	9.6	21.6	-2.0	-4.7	-2.4	-4.3	-3.2	-2.7	-2.5	-2.2	3.6	-3.2	-3.1	-1.4	0.7	4.2	0.5	-3.3	4.5
Length of working week for main job	2.4	2.7	5.5	-2.0	0.6	-2.1	-0.5	-0.6	-1.9	-2.0	-1.4	1.8	1.5	1.5	-2.4	-2.2	1.9	-1.3	-1.7	-0.3
Exposure to tobacco smoke at home	0.3	0.3	1.9	0.2	1.4	0.4	0.2	1.1	0.4	0.4	0.1	-0.9	-0.1	-0.2	0.3	0.7	-0.5	0.1	0.3	0.2
Breastfed as a baby	0.2	0.2	2.4	-0.1	0.8	0.3	0.3	-1.5	0.3	0.3	0.0	0.1	0.2	0.3	0.2	0.2	-0.2	-0.3	0.1	-0.1
Tense / ‘highly strung’	2.5	4.1	8.7	2.9	1.0	2.5	1.1	2.2	2.3	2.6	2.4	-1.6	-0.7	-0.9	2.7	2.4	-1.8	1.5	2.4	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	3.5	0.8	0.1	0.3	0.0	-0.1	0.5	0.4	0.1	-1.9	-0.3	-0.4	0.5	-0.1	-1.4	-0.5	0.7	-0.2
Hair/balding pattern: Pattern 4	0.7	1.8	9.2	-0.4	-2.1	-0.1	-1.4	1.1	-0.6	-0.2	-0.1	1.5	-2.0	-1.9	0.4	1.4	0.4	3.0	-0.0	1.1
Birth weight of first child	0.2	0.4	1.0	0.3	1.0	0.5	0.8	0.7	0.4	0.5	0.9	1.0	0.9	0.8	0.3	0.1	0.2	-0.3	0.1	-0.6
Peak expiratory flow (PEF)	0.3	0.7	1.5	0.8	1.0	0.9	0.8	-0.2	1.1	0.9	1.2	-0.5	0.3	0.2	0.9	0.4	-0.8	-1.2	0.9	-0.9
Pulse wave reflection index	4.2	5.2	9.1	-2.9	-1.6	-2.9	-2.1	0.0	-2.8	-2.8	-3.0	2.9	0.0	0.0	-2.7	-2.2	2.7	-0.6	-3.0	2.0
Ever highly irritable/argumentative for 2 days	3.0	3.6	6.5	2.1	2.1	2.1	1.7	1.7	2.2	2.2	2.2	-2.5	0.0	-0.1	2.1	1.8	-2.3	-0.3	2.3	-1.5
Loud music exposure frequency	3.2	3.5	8.1	0.8	2.4	1.1	2.6	1.9	1.6	1.1	1.3	-1.2	2.5	2.5	0.4	-1.3	-1.7	-2.6	1.5	-2.8
Qualifications: O levels/GCSEs or equivalent	3.3	5.3	9.2	-2.6	-2.4	-2.7	-1.3	-1.2	-2.9	-2.7	-2.6	2.8	1.2	1.6	-3.0	-1.9	3.0	-0.2	-2.9	1.2
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	3.5	-0.3	-1.9	-0.3	-0.8	1.2	-0.6	-0.3	-0.3	0.9	-0.5	-0.6	-0.1	0.3	1.0	0.9	-0.3	0.4
Blood clot in the leg (DVT)	0.4	0.5	1.6	0.6	0.3	1.0	0.4	-0.3	1.0	0.9	1.3	-0.5	-0.5	-0.6	1.1	0.9	-0.4	0.3	0.8	-0.3
Medication: Paracetamol	0.2	0.3	1.9	-0.6	0.0	-0.4	0.1	-0.2	-0.2	-0.3	-0.6	-0.6	-0.0	0.3	-0.4	-1.1	-0.4	-1.4	0.0	-0.6
Headache pain in last month	1.2	2.0	4.9	1.6	1.0	1.6	1.2	1.9	1.8	1.5	1.2	-2.2	-0.4	-0.3	1.5	1.1	-2.0	-0.7	1.6	-0.8
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	4.5	0.0	1.3	-0.1	1.4	0.0	-0.1	0.1	0.4	0.4	2.1	2.1	-0.5	-1.1	0.6	-0.5	-0.1	-1.5
Glaucoma (self-reported)	2.5	2.9	5.6	2.2	2.1	2.2	1.5	0.4	2.0	2.3	2.4	-0.7	0.1	0.1	2.1	1.7	-1.5	1.7	2.1	-1.3
Gout (self-reported)	0.2	0.2	1.7	-0.5	1.3	-0.1	0.1	0.9	-0.0	-0.2	-0.5	-0.1	0.4	0.3	-0.3	-0.6	-0.1	0.1	-0.2	0.1
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	9.7	1.0	-1.2	0.8	-1.0	0.2	0.2	0.8	0.7	0.7	-1.8	-2.0	1.3	2.2	0.4	3.1	0.4	1.1
Medication: Amlodipine	2.2	3.1	9.2	1.7	1.3	1.8	-0.6	0.6	1.3	1.7	1.4	-0.8	-2.3	-2.4	2.3	2.9	-0.9	3.0	1.4	0.9
Medication: Ventolin 100micrograms inhaler	1.2	1.5	3.4	1.5	0.8	1.6	0.5	-0.2	1.3	1.5	1.4	-0.9	-0.9	-0.8	1.7	1.8	-0.9	1.7	1.3	-0.2
Birth weight	0.9	1.8	5.4	-1.2	1.5	-1.1	0.7	-2.3	-1.0	-0.9	-0.1	0.8	2.1	2.2	-1.4	-1.8	0.7	-1.2	-0.8	-0.9
Chronic bronchitis/emphysema (mother)	2.2	2.5	6.8	-1.7	-0.3	-1.7	-0.6	-0.7	-2.0	-1.8	-1.5	2.6	1.2	1.3	-2.1	-1.5	2.5	-0.0	-2.0	0.4
High blood pressure (siblings)	0.6	0.8	2.6	0.3	-0.1	0.4	1.4	0.5	0.7	0.5	0.4	-0.8	1.1	1.3	0.1	-0.8	-1.3	-0.9	1.0	-1.6
Forced vital capacity (FVC), Best measure	1.7	6.3	10.5	-3.0	-2.1	-3.2	-2.8	-2.2	-2.9	-3.2	-3.2	1.8	-0.8	-0.8	-2.8	-2.0	2.6	-1.3	-3.2	2.8
Body fat percentage	2.0	8.0	18.9	3.2	2.5	3.4	2.9	-1.5	3.4	3.3	4.3	-2.0	0.4	0.4	3.2	1.4	-3.6	0.8	3.9	-3.3
Leg fat percentage (right)	2.9	10.4	20.9	3.8	2.7	4.0	3.0	-0.6	4.0	3.9	4.6	-2.9	-0.1	-0.1	3.8	2.1	-4.3	1.1	4.5	-3.2
Arm fat-free mass (right)	0.0	0.2	1.3	0.4	0.1	0.5	0.1	0.7	0.6	0.4	0.4	-0.2	0.0	-0.0	0.5	0.1	0.1	-1.2	0.0	0.2
Exposure to tobacco smoke outside home	0.9	1.2	3.1	-1.8	-0.1	-1.3	-0.5	1.6	-1.2	-1.4	-1.2	1.1	0.5	0.6	-1.4	-1.6	0.8	-0.1	-1.1	0.2
Comparative body size at age 10	1.1	3.0	9.7	-1.6	0.1	-1.7	0.4	0.0	-1.5	-1.8	-1.1	0.9	2.5	2.7	-2.5	-3.1	1.0	-2.3	-1.5	-0.9
Number of full brothers	4.4	5.5	11.9	-3.4	-1.9	-3.3	-1.7	-1.5	-2.8	-3.3	-3.1	0.5	0.5	0.8	-3.4	-3.1	1.2	-1.5	-2.5	1.0
Worry too long after embarrassment	0.7	1.1	2.5	-0.9	-1.2	-1.0	-1.6	1.5	-0.9	-0.9	-0.8	1.2	-0.9	-1.1	-0.5	-0.2	1.6	0.4	-1.1	1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.3	1.3	1.0	0.9	0.2	0.3	0.9	0.9	0.8	-1.5	-0.4	-0.5	1.0	0.7	-1.2	0.9	1.1	-0.3
Wheeze or whistling in the chest in last year	0.4	0.7	2.0	-1.2	0.6	-0.8	-0.7	0.2	-0.8	-0.9	-1.2	1.4	-0.2	-0.1	-0.9	-0.9	0.9	0.4	-1.1	0.7
Number of children fathered	0.4	0.4	2.5	-0.7	-0.2	-0.6	-0.2	-0.2	-0.3	-0.5	-0.6	-0.7	0.6	0.5	-0.7	-0.9	-0.2	-1.6	-0.5	0.3
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.7	3.9	1.6	0.4	1.4	1.9	0.4	1.5	1.3	1.5	-1.0	1.4	1.2	0.9	-0.3	-1.4	-0.8	1.4	-2.0
Age at first live birth	0.5	0.9	4.8	-0.0	-0.1	-0.0	1.3	-0.4	-0.1	0.0	0.1	0.8	2.1	2.2	-0.6	-0.8	0.3	-1.4	-0.1	-1.1
Pulse wave peak to peak time	1.4	1.6	2.7	1.6	1.1	1.6	1.3	0.6	1.5	1.6	1.7	-1.4	0.0	0.0	1.5	1.3	-1.2	0.4	1.6	-1.1
Health satisfaction	1.4	1.8	5.6	1.9	-0.4	1.8	0.5	0.1	1.5	1.7	1.3	-0.7	-1.0	-1.2	2.0	2.4	-1.0	0.8	1.3	0.2
Shortness of breath walking on level ground	0.6	0.7	2.8	0.1	-0.7	0.1	-1.2	0.2	-0.1	-0.1	0.0	0.4	-1.5	-1.6	0.4	0.8	0.1	1.7	-0.0	1.1
Qualifications: College or University degree	0.3	1.1	1.9	-1.3	-1.1	-1.2	-0.3	1.2	-1.4	-1.0	-1.1	1.3	0.9	0.9	-1.3	-0.7	1.2	-0.3	-1.2	0.2
Eye problems/disorders: None of the above	0.5	0.5	2.6	-0.1	0.3	0.1	1.0	0.7	0.2	0.2	0.3	-0.8	1.1	1.1	-0.2	-0.3	-0.4	-1.6	0.3	-1.2
Mouth/teeth dental problems: Loose teeth	1.8	2.1	4.0	-1.7	-1.7	-2.0	-1.4	1.1	-2.0	-1.8	-1.9	0.8	-0.0	0.2	-1.8	-1.1	1.7	-0.0	-1.7	1.0
Emphysema/chronic bronchitis	0.3	0.4	1.1	0.5	0.8	0.6	0.1	0.3	0.4	0.6	0.5	0.0	-0.7	-0.8	0.8	1.1	0.5	0.9	0.3	0.0
Medication for pain relief, constipation, heartburn	0.4	0.8	2.2	-0.7	-0.2	-1.0	-0.7	-1.3	-1.0	-0.9	-0.6	1.3	0.3	0.1	-0.9	-0.2	1.5	0.4	-1.2	0.9
Neck or shoulder pain in last month	0.3	0.4	5.0	-0.1	-0.5	-0.1	-0.2	2.2	-0.2	-0.2	-0.4	0.6	-0.0	0.0	-0.2	0.3	0.2	0.1	-0.4	0.6
Medication: Blood pressure	1.0	1.7	6.6	0.9	-0.4	0.8	-1.2	0.7	0.7	0.6	0.4	-0.8	-2.4	-2.6	1.4	2.1	-1.1	1.3	0.8	1.4
Angina (self-reported)	0.3	0.4	1.2	-0.5	-1.1	-0.6	-0.7	0.3	-0.4	-0.6	-0.7	0.1	-0.3	-0.4	-0.5	-0.5	0.4	-1.0	-0.9	1.0
Migraine (self-reported)	1.0	1.3	3.4	-1.4	-0.3	-1.5	-1.5	-1.3	-1.2	-1.3	-1.8	-0.7	-1.0	-1.0	-1.0	-0.8	-0.2	-0.7	-0.9	1.3
Medication: Ibuprofen	1.8	2.2	6.7	1.6	-0.4	1.7	-0.2	-0.3	1.4	1.5	1.0	-1.2	-2.0	-2.1	2.1	2.6	-1.4	1.1	1.3	0.5
Medication: Allopurinol	0.2	0.3	1.3	-0.7	1.1	0.0	0.6	0.4	0.1	-0.1	-0.3	-0.1	1.0	0.9	-0.3	-0.9	-0.2	-0.7	-0.1	-0.3
Medication: Omeprazole	0.3	0.3	1.7	0.1	-1.3	0.1	-0.4	0.5	-0.1	0.1	0.4	0.4	-0.7	-0.6	0.3	0.4	0.3	1.3	0.1	0.1
Medication: Seretide 50 evohaler	0.6	0.6	2.0	0.7	0.3	0.8	-0.2	0.4	0.8	0.6	0.4	-1.4	-1.1	-1.1	0.9	1.2	-0.8	0.6	0.5	0.5
Mean time to correctly identify matches	4.6	8.8	14.9	-3.3	-1.8	-3.5	-3.8	-0.1	-3.7	-3.4	-3.5	3.9	-2.1	-1.8	-2.8	-1.4	3.7	1.3	-3.6	3.3
Heart disease (mother)	0.3	0.4	1.7	-0.6	0.3	-0.6	-0.1	-0.2	-0.5	-0.7	-0.8	-0.4	0.6	0.6	-0.8	-0.9	0.2	-1.3	-0.4	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.9	-0.6	-0.5	-0.6	-1.3	-0.9	-0.9	-0.6	-0.8	1.5	-1.3	-1.4	-0.2	0.3	1.1	1.7	-0.9	1.4
Whole body fat mass	1.6	6.6	16.2	3.0	2.2	3.2	2.6	-1.1	3.2	3.1	4.0	-1.8	0.3	0.4	3.0	1.3	-3.1	0.2	3.4	-2.8
Leg fat mass (right)	2.2	8.5	19.0	3.5	2.4	3.7	2.8	-0.6	3.7	3.6	4.4	-2.5	-0.0	0.0	3.5	1.9	-3.6	0.4	3.9	-2.9
Arm predicted mass (right)	0.1	0.3	0.8	0.6	-0.0	0.8	0.1	0.4	0.8	0.7	0.7	-0.2	-0.4	-0.5	0.8	0.6	-0.0	-0.9	0.2	0.3
Pulse rate, automated reading	1.5	4.7	9.4	2.0	1.4	2.2	2.7	1.1	2.4	2.2	2.7	-3.1	1.2	1.4	1.7	0.8	-3.0	-0.5	2.9	-3.0
Alcohol intake frequency.	0.8	1.9	3.4	1.7	0.5	1.5	0.5	0.2	1.3	1.6	1.6	-1.2	-1.3	-1.2	1.9	1.8	-1.4	1.6	1.8	-1.0
Comparative height size at age 10	0.2	1.0	4.3	0.7	-2.1	0.3	-0.9	-1.6	0.3	0.3	0.9	0.8	-1.2	-1.4	0.8	1.1	0.8	-0.3	-0.1	0.9
Number of full sisters	0.3	0.4	1.5	0.9	0.5	0.8	0.3	-1.2	0.8	0.7	0.8	-0.4	-0.4	-0.4	0.8	0.2	-0.6	-0.0	0.5	-0.1
Suffer from ‘nerves’	1.7	2.7	9.6	1.2	-2.5	0.8	-1.7	-0.1	0.5	0.9	0.4	-0.8	-3.0	-3.1	1.7	2.4	-0.1	1.6	0.5	1.7
Overall health rating	0.6	1.2	5.6	1.1	0.6	0.8	-0.4	1.2	0.5	0.8	0.5	-0.3	-1.5	-1.4	1.2	1.3	-1.1	2.4	0.9	0.6
Chest pain or discomfort	0.2	0.4	1.5	-0.6	0.7	-0.5	-0.5	0.6	-0.3	-0.6	-0.8	-1.2	-0.5	-0.3	-0.5	-0.7	-0.8	0.2	0.0	0.2
Had major operations	0.5	0.6	1.7	-0.9	-0.8	-0.7	0.3	0.3	-0.6	-0.8	-0.5	0.3	1.1	1.3	-1.2	-0.9	-0.1	-1.2	-0.5	-0.4
Age at last live birth	1.0	1.4	4.1	0.9	0.7	1.0	2.0	0.6	1.0	1.1	1.1	-0.9	1.8	1.7	0.6	0.1	-1.0	-1.3	1.0	-1.6
Family relationship satisfaction	0.2	0.3	1.3	-0.4	0.1	-0.6	-0.0	-0.7	-0.5	-0.6	-0.5	0.7	0.4	0.5	-0.7	-1.1	0.1	-0.1	-0.4	0.0
Leg pain on walking	0.3	0.4	1.5	0.7	0.0	0.6	0.9	1.2	0.5	0.4	0.6	0.0	1.0	0.9	0.2	-0.2	-0.5	0.2	0.5	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.1	1.0	-0.1	1.1	0.7	-0.1	0.8	1.0	0.9	-0.1	0.0	0.1	0.9	1.0	-0.5	0.8	0.9	-0.5
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.6	-0.1	0.6	-0.0	-0.1	-0.8	-0.2	-0.1	-0.2	0.3	0.2	0.1	-0.1	0.3	0.3	0.3	-0.2	0.4
Illness, injury, bereavement, stress in last 2 years	1.8	2.2	4.0	1.6	1.9	1.7	2.0	-0.8	1.7	1.7	1.9	-1.4	1.3	1.3	1.3	0.6	-1.3	-0.6	1.5	-1.8
Medication: Aspirin	0.8	1.0	4.0	0.4	-0.3	0.4	1.1	0.3	0.8	0.3	0.0	-1.9	0.8	0.9	0.1	-0.8	-2.0	-1.9	0.8	-1.1
Supplements: Vitamin C	0.6	0.7	1.6	1.3	-0.7	1.0	1.1	-0.4	0.9	1.0	0.8	-0.6	0.6	0.6	0.8	0.8	-0.8	-0.3	0.8	-0.8
Knee pain experienced in last month	0.6	1.0	2.8	1.0	-1.2	1.4	0.4	-0.5	1.1	1.2	1.2	0.1	-0.7	-0.8	1.4	1.7	-0.7	0.6	1.0	-0.1
Hypertension (Self-reported)	0.5	1.3	3.0	1.2	-1.1	1.2	-0.5	-0.3	0.9	1.1	0.8	-0.6	-1.5	-1.6	1.5	1.6	-1.0	1.7	1.1	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	3.8	-0.2	-0.7	-0.6	0.5	-0.9	-0.2	-0.5	-0.2	-0.1	1.2	1.3	-0.9	-1.5	-0.6	-2.0	-0.2	-0.9
Illnesses of father: Heart disease	0.5	0.7	1.4	-1.0	-0.4	-0.8	-0.0	-0.8	-1.0	-0.9	-0.6	1.2	0.9	1.1	-1.2	-1.0	0.6	0.0	-0.9	0.1
Illnesses of siblings: Diabetes	0.4	0.4	1.7	-0.5	-1.2	-0.6	-0.3	0.6	-0.3	-0.5	-1.1	-0.2	0.4	0.1	-0.6	-0.5	0.1	-1.3	-0.7	0.8
Smoking status: Previous	3.0	4.4	10.5	-2.1	-0.2	-1.6	-3.0	-0.8	-2.1	-1.6	-1.8	2.2	-2.9	-2.6	-0.8	0.5	2.1	3.2	-1.8	2.9
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	5.7	-0.6	-2.3	-1.0	-2.1	-1.9	-1.2	-0.9	-1.2	1.2	-2.0	-1.9	-0.3	1.0	1.7	0.6	-1.4	2.4
Whole body fat-free mass	0.0	0.2	2.4	0.1	-0.4	0.1	0.1	0.3	0.3	0.0	0.3	-0.0	0.4	0.3	0.0	-0.4	0.2	-1.5	-0.2	0.1
Leg fat-free mass (right)	0.1	0.8	4.1	-0.0	0.3	0.1	0.9	0.3	0.3	-0.0	0.6	0.3	1.6	1.6	-0.3	-1.3	0.1	-2.0	-0.2	-0.8
Arm fat percentage (left)	1.9	7.4	15.9	2.6	3.0	2.9	3.5	-0.6	3.1	2.8	3.9	-2.1	1.8	1.9	2.3	0.1	-3.5	-0.5	3.5	-4.0
Average weekly red wine intake	1.1	1.6	4.2	1.3	1.0	1.3	1.7	0.9	1.2	1.3	1.8	-0.8	1.5	1.3	0.9	0.1	-0.9	0.4	1.5	-2.1
Handedness (chirality/laterality): Left-handed	0.9	1.0	3.4	1.1	0.4	1.1	0.1	0.2	1.0	1.0	0.7	-1.8	-1.0	-1.1	1.3	1.5	-1.3	0.8	0.9	0.5
Mood swings	1.8	3.3	8.0	2.2	0.3	1.6	-0.3	1.4	1.7	1.7	1.0	-2.1	-2.8	-2.7	2.4	2.2	-2.4	0.8	1.7	0.7
Loneliness, isolation	1.9	2.6	7.1	1.4	0.2	1.5	-0.6	1.6	1.4	1.4	1.1	-1.0	-2.5	-2.7	2.1	2.5	-1.3	1.6	1.4	0.8
Long-standing illness, disability or infirmity	0.7	1.1	7.7	0.9	-0.1	1.0	-0.0	1.1	0.4	1.0	0.8	0.6	-0.8	-0.6	1.1	1.8	0.1	2.8	0.5	0.4
Ever had bowel cancer screening	0.4	0.5	1.2	-0.2	-0.5	-0.3	-0.9	-0.9	-0.4	-0.3	-0.4	1.0	-0.8	-0.8	-0.0	0.4	1.1	0.7	-0.7	1.1
Diabetes diagnosed by doctor	1.0	1.6	4.2	-1.4	-1.1	-1.5	-1.7	-0.4	-1.6	-1.5	-2.1	0.3	-0.9	-0.7	-1.3	-0.9	0.7	0.6	-1.5	1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	3.4	0.8	1.3	0.7	1.7	-0.5	0.9	0.7	0.8	-0.5	1.7	1.5	0.2	-0.6	-0.7	-1.9	0.8	-1.8
Friendships satisfaction	2.1	2.5	8.4	1.5	0.2	1.4	-0.3	-0.6	1.2	1.5	1.2	-1.3	-2.3	-2.3	2.1	2.9	-1.8	1.5	1.4	0.9
Qualifications: nursing, teaching	0.1	0.2	1.0	-0.1	-1.0	-0.1	-0.5	-0.6	-0.2	-0.1	0.2	0.3	-0.5	-0.5	0.1	0.3	-0.0	0.9	0.1	0.3
Commuting to job workplace: Walk	0.4	0.4	1.8	0.3	0.6	0.5	0.9	1.3	0.4	0.5	0.8	-0.2	0.8	0.8	0.3	-0.1	-0.0	0.3	0.5	-1.1
Eye problems/disorders: Cataract	0.1	0.2	0.6	0.6	-0.7	0.2	0.0	-0.8	0.4	0.1	0.4	-0.1	0.1	0.0	0.2	-0.4	-0.3	-0.5	0.4	-0.4
Mouth/teeth dental problems: Mouth ulcers	2.9	4.6	12.3	1.0	1.3	1.4	3.1	3.2	1.5	1.3	1.6	-1.5	3.4	3.5	0.2	-1.2	-1.7	-1.8	1.5	-3.3
Medication for cholesterol	0.3	0.5	5.5	-0.6	2.3	-0.3	0.0	0.9	-0.2	-0.4	-0.2	0.4	0.2	0.1	-0.3	-0.3	0.6	-0.4	-0.4	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	1.2	-0.5	0.0	-0.4	-0.5	-1.1	-0.5	-0.4	0.0	0.4	-0.4	-0.4	-0.2	-0.3	0.4	0.9	-0.3	0.2
Back pain experienced in last month	0.5	0.7	1.4	-0.9	0.5	-0.9	-0.3	1.1	-0.8	-0.9	-1.0	1.1	0.9	0.7	-1.1	-1.2	0.6	-0.5	-0.8	0.1
Mineral and other dietary supplements	0.2	0.3	1.3	-0.3	0.1	-0.1	-0.8	-0.3	-0.1	-0.1	-0.1	0.5	-1.1	-1.1	0.2	0.2	0.4	0.4	-0.1	0.6
Breast cancer (self-reported)	1.4	1.6	3.7	-1.6	0.8	-1.6	-1.2	0.7	-1.5	-1.5	-1.8	1.9	-0.2	-0.1	-1.4	-1.1	1.3	0.3	-1.5	1.1
Asthma (self-reported)	0.1	0.2	0.5	-0.6	0.6	-0.3	-0.3	0.5	-0.4	-0.3	-0.7	0.6	-0.5	-0.4	-0.2	-0.3	0.6	-0.0	-0.6	0.4
Osteoporosis (self-reported)	0.8	0.9	1.8	-1.3	-0.0	-1.2	-0.6	-0.2	-1.4	-1.3	-0.9	1.3	0.3	0.5	-1.3	-1.1	1.1	0.6	-1.1	0.3
Osteoarthritis (self-reported)	1.1	1.4	2.9	1.6	1.0	1.7	0.7	0.3	1.1	1.5	1.7	0.7	-0.1	-0.3	1.5	1.7	0.2	1.7	1.1	-0.8
Medication: Aspirin	0.4	0.6	2.3	0.2	-0.1	0.1	0.6	0.2	0.4	0.0	-0.3	-1.4	0.7	0.7	-0.2	-0.8	-1.5	-1.5	0.4	-0.6
Medication: Gliclazide	0.6	0.6	1.3	-1.0	-1.1	-0.8	-0.8	-0.8	-0.9	-0.8	-1.0	1.1	-0.6	-0.5	-0.6	0.0	0.6	0.4	-0.7	0.8
Illnesses of father: None of the above (group 1)	1.8	2.2	5.4	1.7	-0.1	2.0	0.2	-0.5	1.8	2.0	2.0	-0.5	-1.4	-1.5	2.3	2.2	-0.6	1.1	1.6	-0.3
Smoking status: Current	1.7	2.7	5.2	-1.4	-1.0	-2.1	-0.9	0.2	-2.0	-2.0	-1.9	2.2	1.0	1.0	-2.3	-2.2	1.9	-0.9	-2.1	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.9	-0.5	0.3	-0.5	-0.4	-1.4	-0.3	-0.5	-0.6	-0.2	-0.1	-0.3	-0.3	-0.4	-0.2	-0.3	-0.3	0.5
Whole body water mass	0.0	0.2	2.3	0.1	-0.2	0.1	0.1	0.4	0.3	0.0	0.3	-0.1	0.3	0.3	0.0	-0.4	0.1	-1.5	-0.2	0.2
Leg predicted mass (right)	0.1	0.7	4.0	-0.1	0.3	0.1	0.8	0.3	0.3	-0.0	0.5	0.4	1.5	1.5	-0.4	-1.2	0.1	-2.0	-0.2	-0.8
Arm fat mass (left)	1.2	4.8	11.0	2.3	2.1	2.6	2.5	-0.6	2.7	2.5	3.3	-1.8	0.9	0.9	2.2	0.5	-2.8	-0.4	2.9	-2.8
Number of self-reported non-cancer illnesses	0.5	0.9	3.7	0.5	-1.0	0.1	-1.3	-0.7	-0.2	0.2	0.1	0.3	-1.8	-1.7	0.6	1.0	0.2	1.9	0.1	0.9
Average weekly champagne plus white wine intake	0.4	0.5	2.8	0.1	-0.6	0.3	1.0	-0.3	0.6	0.4	0.3	-0.8	0.9	0.7	0.2	-0.5	-1.0	-1.7	0.6	-0.8
Miserableness	1.2	2.0	16.5	1.4	-0.2	1.2	-0.1	4.1	1.1	1.2	0.6	-1.1	-1.3	-1.6	1.6	1.6	-0.7	-0.0	0.8	0.3
Guilty feelings	0.3	0.5	5.0	0.4	0.6	0.2	-0.3	2.2	0.2	0.2	0.3	-0.6	-0.6	-0.8	0.4	1.0	-0.1	0.6	0.2	0.5
Wears glasses or contact lenses	0.6	0.7	1.7	0.4	-0.6	0.7	-0.6	-1.3	0.5	0.7	0.7	0.0	-1.1	-1.3	1.0	1.3	0.1	1.3	0.4	0.8
Ever taken oral contraceptive pill	1.0	1.1	2.9	-1.3	-0.8	-1.1	-1.3	-0.2	-1.2	-1.2	-1.6	0.6	-0.8	-0.8	-0.9	-0.2	0.7	0.2	-1.3	1.7
Hearing aid user	1.0	1.1	3.4	-1.1	-0.9	-0.9	-1.3	-0.7	-0.5	-1.0	-1.4	-0.6	-1.0	-1.1	-0.6	-0.1	-0.0	-1.8	-0.9	1.8
Mother’s age at death	1.2	1.5	5.6	-0.1	-2.4	-0.5	-1.6	0.2	-0.6	-0.4	-0.9	0.2	-2.3	-2.2	0.2	1.1	0.3	0.9	-0.5	1.6
Financial situation satisfaction	0.4	0.5	3.2	0.1	-0.1	0.3	-0.4	-0.3	0.0	0.3	0.2	-0.7	-1.1	-0.9	0.6	1.0	-0.8	1.8	0.5	0.7
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.7	-0.9	-1.6	-1.0	-0.3	0.1	-0.7	-1.0	-1.4	-0.0	0.6	0.6	-1.1	-1.1	0.3	-1.3	-1.0	0.7
Commuting to job workplace: Public transport	2.5	2.9	10.1	-1.5	0.3	-1.5	0.9	0.8	-0.9	-1.5	-1.0	0.0	2.6	2.7	-2.2	-3.2	-0.1	-2.8	-0.7	-1.5
Eye problems/disorders: Glaucoma	5.0	5.9	10.4	3.1	2.1	3.1	2.3	0.5	2.9	3.2	3.2	-1.8	0.2	0.1	3.0	2.2	-2.6	2.0	3.1	-2.1
Medication: Blood pressure	0.4	0.7	3.2	-0.1	-1.8	-0.5	-0.8	-1.7	-0.8	-0.4	-0.4	0.9	-0.3	-0.1	-0.4	-0.1	0.5	1.4	-0.5	0.5
Pain type(s) experienced in last month: Hip pain	0.9	1.1	4.4	0.5	-0.8	0.4	-0.8	-0.6	0.3	0.5	0.1	-0.7	-2.1	-2.0	1.0	1.5	-1.1	1.4	0.5	1.1
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.3	0.8	1.1	0.6	0.9	0.9	0.6	0.6	0.8	-0.5	0.8	0.7	0.4	0.2	-0.4	-0.1	0.6	-0.8
High cholesterol (Self-reported)	0.3	0.5	1.6	-0.6	-0.9	-0.9	-0.3	-1.0	-0.7	-0.9	-0.9	-0.1	0.5	0.7	-1.1	-1.3	-0.1	-0.5	-0.5	-0.2
Medication: Bendroflumethiazide	0.9	1.4	4.7	0.9	-1.2	0.8	-0.6	-2.1	0.2	0.8	0.7	-0.0	-1.4	-1.4	1.2	2.0	-0.0	2.2	0.6	0.7
Medication: Paracetamol	0.1	0.2	0.7	0.1	0.6	0.2	-0.1	-0.1	0.3	0.2	0.0	-0.6	-0.8	-0.7	0.4	-0.2	-0.7	-0.3	0.5	-0.3
Medication: Lisinopril	0.4	0.5	1.8	-0.5	-1.2	-0.5	-0.6	1.3	-0.3	-0.6	-1.0	-0.0	-0.2	-0.3	-0.5	-0.7	0.3	-1.2	-0.7	0.7
Medication: Atorvastatin	0.7	0.9	3.2	-0.7	-0.8	-0.8	0.3	0.4	-0.5	-0.8	-0.8	-0.6	1.4	1.5	-1.2	-1.6	-0.1	-1.8	-0.7	-0.3
Illnesses of father: High blood pressure	0.3	0.4	2.6	-0.5	0.9	-0.7	-0.4	1.6	-0.5	-0.6	-0.8	-0.3	-0.4	-0.3	-0.5	-0.5	-0.3	0.3	-0.2	0.2
Alcohol drinker status: Never	1.9	2.3	4.8	1.7	0.6	1.9	0.6	-0.2	1.7	1.9	2.0	-0.7	-1.1	-1.3	2.2	2.2	-1.4	1.1	1.8	-0.6
Ever smoked	2.7	4.8	11.3	-2.7	-0.8	-2.5	-2.4	-0.3	-2.9	-2.5	-2.4	3.4	-0.9	-0.7	-2.2	-1.1	3.0	1.5	-2.6	2.1
Basal metabolic rate	0.1	0.3	1.7	0.6	-0.1	0.6	0.4	0.2	0.8	0.5	0.9	-0.2	0.2	0.2	0.5	-0.1	-0.3	-1.3	0.3	-0.3
Leg fat percentage (left)	2.3	8.4	16.9	3.4	2.5	3.6	2.7	-0.9	3.6	3.5	4.1	-2.3	-0.1	-0.0	3.5	1.7	-3.8	1.3	4.0	-2.9
Arm fat-free mass (left)	0.1	0.3	0.6	0.6	-0.3	0.7	-0.1	0.3	0.7	0.6	0.6	-0.3	-0.5	-0.6	0.8	0.6	-0.1	-0.6	0.2	0.5
Number of operations (self-reported)	1.0	1.4	4.3	-0.9	1.6	-0.7	0.8	0.0	-0.6	-0.7	-0.5	0.9	2.0	2.1	-1.3	-1.8	0.5	-1.8	-0.8	-0.7
Average weekly beer plus cider intake	2.5	3.6	6.9	-2.3	-0.5	-2.2	-0.3	-0.2	-2.1	-2.2	-2.2	2.4	1.7	1.9	-2.6	-2.6	2.1	-1.2	-2.3	0.3
Irritability	0.5	0.8	7.4	0.4	1.7	0.0	0.3	2.7	0.4	0.1	-0.1	-0.6	0.1	0.0	0.1	-0.4	-1.2	-1.0	0.4	-0.3
Risk taking	1.0	1.5	4.0	-1.5	-1.0	-1.3	-0.0	0.7	-1.1	-1.3	-1.4	0.5	1.3	1.5	-1.6	-2.0	0.7	-1.6	-1.2	-0.3
Ever had prostate specific antigen (PSA) test	2.0	2.3	6.9	1.1	-2.5	1.2	-0.2	0.5	1.4	1.1	0.6	-2.6	-1.6	-1.8	1.5	2.0	-2.1	-0.6	1.4	0.6
Fractured/broken bones in last 5 years	0.6	0.8	2.8	-0.7	-1.1	-0.6	-1.0	-1.5	-0.2	-0.5	-0.7	-0.5	-1.3	-1.3	-0.1	0.1	-0.0	-1.7	-0.4	1.0
Age started oral contraceptive pill	0.9	1.1	2.9	1.3	1.6	1.0	1.0	1.5	0.7	1.1	1.0	0.4	0.5	0.5	0.9	0.5	-0.4	1.7	0.8	-1.0
Diastolic blood pressure, automated reading	1.3	4.2	7.7	2.5	-0.1	2.6	1.6	0.3	2.6	2.7	2.3	-2.3	-0.9	-0.8	2.8	2.3	-2.6	0.0	2.8	-1.6
Ever depressed for a whole week	0.1	0.2	1.0	-0.0	-0.3	-0.0	-0.5	1.0	0.0	0.1	-0.2	-0.3	-0.7	-0.7	0.3	0.2	-0.1	-0.4	0.1	0.3
Unable to work because of sickness or disability	0.7	0.9	2.4	-1.2	0.4	-1.4	-0.3	0.1	-1.3	-1.3	-0.9	0.6	0.7	0.9	-1.6	-1.4	0.6	-0.2	-1.0	0.1
Commuting to job workplace: Cycle	0.4	0.5	1.6	0.8	-0.2	0.6	-0.1	0.8	0.4	0.6	0.8	-0.9	-0.8	-0.7	0.8	1.3	-0.2	0.9	0.6	0.1
Myopia	0.6	0.9	3.7	0.7	0.0	1.0	1.0	-1.4	1.2	1.2	0.8	-0.9	0.4	0.2	1.1	0.2	-0.7	-1.9	0.8	-0.9
Vascular/heart problems diagnosed by doctor	0.4	1.2	2.2	-1.2	0.8	-1.3	0.1	0.1	-1.1	-1.2	-0.9	1.1	1.2	1.2	-1.5	-1.4	1.4	-1.2	-1.3	-0.1
Cholesterol lowering medication	0.7	1.0	3.5	-0.9	-1.8	-1.1	-0.6	-0.7	-0.9	-1.1	-1.4	0.5	0.4	0.5	-1.3	-1.9	0.4	-0.8	-1.0	0.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.0	-0.6	-1.0	-0.6	-0.3	0.8	-0.7	-0.6	-0.3	0.6	0.2	0.2	-0.6	-0.6	0.5	0.5	-0.5	0.0
Pain experienced in last month	0.4	0.6	8.1	-0.1	0.4	-0.5	0.1	-2.9	-0.5	-0.3	-0.1	0.1	0.7	0.5	-0.5	-0.6	0.7	-0.0	-0.5	-0.1
Supplements: Calcium	0.3	0.4	1.9	-0.2	0.0	-0.1	0.1	0.4	-0.5	-0.1	0.1	1.4	0.4	0.5	-0.3	-0.4	1.1	1.2	-0.4	-0.2
Basal cell carcinoma (self-reported)	0.7	0.8	2.8	0.3	-1.3	0.4	0.7	0.2	0.7	0.5	0.2	-1.6	0.2	0.3	0.4	-0.2	-1.6	-1.7	1.0	-0.9
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.1	-1.3	1.2	-1.5	-1.0	-0.0	-1.3	-1.5	-1.3	0.5	0.1	0.1	-1.4	-1.1	0.8	-0.5	-1.4	1.1
Deep venous thrombosis (DVT) (self-reported)	0.7	0.8	2.4	0.9	0.7	1.3	0.7	-0.3	1.3	1.2	1.5	-0.7	-0.3	-0.4	1.3	1.0	-0.6	-0.1	1.0	-0.6
Heart disease (siblings)	0.3	0.3	1.5	-0.2	-1.2	-0.3	-0.8	0.5	-0.2	-0.3	-0.3	0.0	-0.9	-0.8	-0.1	0.5	0.1	0.4	-0.2	0.9
Alcohol drinker status: Previous	0.2	0.2	1.8	0.0	-1.3	0.0	-0.3	-0.6	-0.1	0.1	0.3	-0.5	-0.3	-0.4	0.2	0.5	0.3	0.8	0.0	0.2
Pack years of smoking	0.8	1.2	2.2	1.4	0.4	1.2	1.5	-0.6	1.3	1.1	1.3	-0.7	1.1	1.0	0.8	-0.2	-1.0	-1.1	1.1	-1.5
Impedance of whole body	0.5	2.5	9.3	-0.3	-2.0	-0.6	-1.9	-3.0	-0.9	-0.5	-0.1	1.6	-2.2	-2.1	0.1	1.5	1.4	2.1	-0.5	1.4
Leg fat mass (left)	1.8	7.2	16.5	3.2	2.2	3.5	2.5	-0.7	3.5	3.3	4.1	-2.1	0.0	0.1	3.3	1.7	-3.3	0.6	3.6	-2.7
Arm predicted mass (left)	0.1	0.4	1.0	0.7	-0.1	0.8	-0.1	0.5	0.9	0.7	0.7	-0.3	-0.7	-0.7	1.0	0.8	-0.2	-0.5	0.3	0.5