Best TWAS P=1.23e-07 · Best GWAS P=4.48e-10 conditioned to 7.03e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C2orf47 | 0.05 | 0.02 | blup | 361 | 0.02 | 4.3e-03 | 4.0 | -5.2 | 1.5e-07 | 0.47 | 0.81 | 0.09 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | TYW5 | 0.08 | 0.14 | lasso | 8 | 0.13 | 2.2e-15 | 4.9 | -5.3 | 1.4e-07 | 0.50 | 0.74 | 0.26 | FALSE |
| 3 | GTEx | Brain Nucleus accumbens basal ganglia | C2orf47 | 0.25 | 0.01 | lasso | 3 | 0.00 | 2.8e-01 | -5.8 | 5.2 | 2.5e-07 | -0.84 | 0.04 | 0.62 | FALSE |
| 4 | GTEx | Testis | C2orf69 | 0.14 | 0.09 | enet | 17 | 0.10 | 2.7e-05 | 4.0 | 5.3 | 1.2e-07 | -0.55 | 0.49 | 0.33 | TRUE |