[Hub]/) : Traits : Systolic Blood Pressure :

chr2:202,952,678-204,549,680

Best TWAS P=4.03e-13 · Best GWAS P=1.54e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CARF 0.17 0.07 enet 23 0.09 6.2e-08 6.5 -6.9 3.9e-12 -0.88 0.04 0.96 FALSE
2 GTEx Artery Aorta CARF 0.07 0.00 lasso 5 0.00 2.5e-01 7.0 -7.2 4.0e-13 -0.96 0.02 0.81 TRUE
3 GTEx Artery Tibial CARF 0.05 0.02 lasso 3 0.02 7.5e-03 3.5 -5.6 2.3e-08 -0.77 0.06 0.81 FALSE
4 GTEx Cells Transformed fibroblasts CARF 0.11 0.11 enet 13 0.13 8.0e-10 7.0 -6.5 6.8e-11 -0.88 0.03 0.97 FALSE
5 GTEx Colon Sigmoid CARF 0.12 0.06 enet 11 0.06 3.4e-03 7.0 -6.5 8.3e-11 -0.85 0.03 0.84 FALSE
6 GTEx Colon Transverse CARF 0.09 0.04 enet 12 0.03 1.1e-02 -6.2 -7.0 2.0e-12 -0.89 0.04 0.86 FALSE
7 GTEx Esophagus Muscularis CARF 0.09 0.07 enet 20 0.10 1.4e-06 5.0 -6.2 4.5e-10 -0.84 0.03 0.96 FALSE
8 GTEx Heart Atrial Appendage CARF 0.09 0.02 enet 13 0.03 1.2e-02 7.3 -6.4 1.7e-10 -0.83 0.02 0.82 FALSE
9 GTEx Muscle Skeletal ICA1L 0.18 0.14 lasso 8 0.14 5.5e-14 3.5 5.3 1.2e-07 0.70 1.00 0.00 FALSE
10 GTEx Nerve Tibial CARF 0.08 0.07 enet 12 0.06 3.8e-05 6.1 -6.1 1.0e-09 -0.87 0.02 0.98 FALSE
11 GTEx Skin Sun Exposed Lower leg CARF 0.11 0.09 lasso 3 0.10 5.0e-09 7.3 -6.8 7.8e-12 -0.92 0.01 0.99 FALSE
12 GTEx Thyroid CARF 0.09 0.05 enet 26 0.07 3.2e-06 7.0 -5.6 1.8e-08 -0.77 0.04 0.96 FALSE
13 METSIM Adipose CARF 0.07 0.02 lasso 5 0.03 8.8e-06 6.9 -6.7 2.1e-11 -0.85 0.02 0.98 FALSE