Hub : Genes

ICA1L

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0890	0.0360	6.4e-05	0.064	0.045	0.046	0.053	0.057	3.0e-08	3.1e-06	2.3e-06	5.0e-07	1.9e-07
2	GTEx	Adipose Subcutaneous	0.1080	0.0420	2.4e-04	0.063	NA	0.010	NA	0.033	7.1e-06	NA	4.8e-02	NA	9.9e-04
3	GTEx	Cells Transformed fibroblasts	0.1490	0.0490	8.2e-06	0.111	NA	0.087	NA	0.092	1.1e-08	NA	4.7e-07	NA	2.3e-07
4	GTEx	Muscle Skeletal	0.1788	0.0477	5.2e-12	0.145	NA	0.143	NA	0.144	4.5e-14	NA	6.5e-14	NA	5.5e-14
5	GTEx	Nerve Tibial	0.1181	0.0434	1.0e-04	0.105	NA	0.095	NA	0.077	7.5e-08	NA	3.1e-07	NA	4.0e-06
6	GTEx	Pancreas	0.1680	0.0680	1.6e-03	0.068	NA	0.094	NA	0.101	7.7e-04	NA	9.2e-05	NA	4.9e-05
7	GTEx	Skin Not Sun Exposed Suprapubic	0.1010	0.0500	3.6e-03	0.017	NA	0.025	NA	0.030	3.9e-02	NA	1.5e-02	NA	8.8e-03
8	GTEx	Thyroid	0.1070	0.0400	1.9e-04	0.111	NA	0.101	NA	0.096	7.9e-09	NA	3.8e-08	NA	7.9e-08
9	METSIM	Adipose	0.1052	0.0375	6.4e-07	0.039	0.046	0.047	0.049	0.048	1.6e-06	1.5e-07	1.5e-07	6.7e-08	1.0e-07
10	ROSMAP	Brain Pre-frontal Cortex	0.2026	0.0461	0.0e+00	0.151	0.184	0.189	0.177	0.171	6.6e-19	4.6e-23	9.5e-24	4.0e-22	1.9e-21
11	TCGA	Colon Adenocarcinoma	0.0980	0.0550	3.6e-03	0.008	0.023	0.021	NA	0.020	1.1e-01	1.6e-02	2.2e-02	NA	2.4e-02
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0536	0.0298	1.3e-03	0.018	0.017	0.016	NA	0.019	3.7e-03	4.4e-03	5.7e-03	NA	2.8e-03
13	TCGA	Liver Hepatocellular Carcinoma	0.0900	0.0450	1.2e-03	0.044	0.034	0.033	NA	0.028	4.0e-03	9.6e-03	1.1e-02	NA	1.8e-02
14	TCGA	Thyroid Carcinoma	0.0610	0.0290	5.9e-04	0.006	0.018	0.014	NA	0.010	7.9e-02	6.9e-03	1.3e-02	NA	3.2e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	1.3	2.0	4.3	-1.9	1.6	1.6	1.2	1.7	0.6	2.0	1.6	0.8	-2.1	1.0	0.8	0.3	1.0
Bipolar Disorder or Schizophrenia	0.1	0.3	1.3	-0.5	0.3	0.3	0.6	0.1	0.6	1.2	0.2	0.7	-0.2	0.3	0.8	1.0	0.5
Depressed Affect (Nagel 2018)	7.0	14.6	26.8	4.7	-4.7	-4.7	-3.2	-3.9	-2.7	-3.2	-4.6	-3.4	5.2	-3.8	-3.2	-1.5	-3.0
Depression (Nagel 2018)	2.7	4.0	7.9	2.2	-2.4	-2.4	-1.7	-1.7	-0.8	-1.4	-2.3	-2.8	2.3	-2.1	-2.1	-1.5	-1.4
Intelligence (Savage-Jansen 2018)	0.3	1.0	5.4	-1.1	1.0	1.1	-0.3	0.9	-0.7	-0.5	1.1	0.2	-2.3	0.4	-0.1	-1.2	-0.6
Neuroticism (Nagel 2018)	3.6	8.4	14.1	3.6	-3.4	-3.5	-2.1	-2.7	-2.1	-2.4	-3.5	-3.1	3.8	-2.5	-2.7	-1.6	-2.5
Schizophrenia (2018)	0.3	0.6	2.2	1.0	-1.0	-0.9	-0.3	-1.2	0.2	-0.1	-1.0	0.2	1.5	-0.5	0.3	1.0	-0.2
Schizophrenia vs Biploar Disorder	5.7	7.5	15.8	3.6	-3.3	-3.4	-2.4	-3.4	-0.9	-2.1	-3.3	-1.8	4.0	-2.6	-2.0	-0.6	-2.2
Worry (Nagel 2018)	0.6	1.2	4.8	1.6	-1.3	-1.4	-0.2	-0.6	-0.1	-0.9	-1.3	-1.3	2.2	-0.2	-0.7	-0.2	-0.5
Alzheimer’s Disease (in mother)	1.2	1.4	2.5	1.1	-1.3	-1.3	-1.2	-1.1	-0.0	-1.4	-1.3	-1.6	0.7	-1.2	-1.3	-1.2	-1.1
Alzheimer’s Disease (in father)	11.7	12.7	17.6	3.9	-3.6	-3.7	-4.2	-3.5	-3.3	-3.9	-3.7	-3.4	2.3	-4.1	-3.6	-2.6	-3.5
Alzheimer’s Disease (including proxy)	9.5	13.7	18.6	3.9	-3.8	-3.9	-3.9	-3.5	-2.5	-4.3	-3.9	-4.2	2.5	-4.0	-3.9	-3.1	-3.8
Crohns Disease (2017)	1.7	3.8	8.4	-2.2	2.2	2.2	1.5	2.0	1.7	2.6	2.2	1.7	-2.9	1.6	1.2	0.2	1.8
Irritable Bowel Disease (IBD)	0.6	1.3	4.6	-1.2	1.1	1.1	0.6	0.9	1.0	2.1	1.1	1.3	-1.6	0.6	0.8	0.4	1.1
Ulcerative Colitis (UC)	0.1	0.2	0.8	0.3	-0.4	-0.4	-0.5	-0.5	-0.0	0.9	-0.4	0.3	0.2	-0.7	-0.1	0.2	-0.1
Major Depression (MDD)	0.6	0.8	1.3	1.0	-1.0	-1.0	-1.1	-0.9	0.0	-1.1	-1.0	-1.0	0.9	-1.0	-0.6	0.2	-0.5
Reaction Time	1.2	2.3	8.0	-1.6	1.7	1.6	1.1	1.6	2.8	1.6	1.7	0.7	-2.0	1.3	0.6	-0.3	0.8
Verbal and Numeric Reasoning (VNR)	0.4	1.0	3.9	-1.2	1.2	1.2	-0.0	1.1	-1.0	-0.0	1.2	0.9	-2.0	0.5	0.4	-0.5	-0.2
Breast Cancer	1.7	4.1	11.0	-1.4	1.7	1.7	1.5	1.5	1.1	1.0	1.7	2.6	-0.9	1.8	3.1	3.3	2.9
Ovarian Cancer	4.7	6.2	9.0	-2.8	2.7	2.8	2.0	2.5	3.0	2.8	2.7	1.9	-2.5	2.3	2.5	1.8	2.1
Prostate Cancer	0.5	0.8	1.6	1.2	-1.1	-1.1	-0.6	-1.0	-1.2	-0.8	-1.1	-0.3	1.2	-0.7	-0.3	0.1	-0.3
Age at First Birth	2.0	2.8	5.1	-1.6	1.9	1.8	2.0	2.1	1.8	0.9	1.8	1.5	-1.3	2.3	1.7	0.8	1.5
Bipolar Disorder (2011)	2.7	2.6	5.0	-2.0	2.0	2.1	1.4	1.9	0.6	1.0	2.0	1.1	-2.2	1.5	1.4	0.6	1.5
Body Mass Index (BMI) (2010)	3.9	5.3	8.5	2.3	-2.4	-2.4	-2.9	-2.3	-1.4	-2.1	-2.4	-2.5	1.2	-2.9	-2.5	-2.1	-2.4
Coronary Artery Disease (CAD)	26.8	32.0	43.7	-6.4	6.6	6.6	6.4	6.1	4.1	4.3	6.4	5.6	-5.0	6.6	5.3	3.5	5.3
Crohns Disease (2012)	0.7	1.2	5.4	-0.9	1.0	0.9	0.4	0.8	2.3	2.1	1.0	0.5	-1.2	0.4	0.4	-0.3	0.6
Mean Putamen Volume	1.0	1.2	3.8	0.9	-0.6	-0.7	-0.8	-0.4	-0.5	-2.0	-0.6	-1.5	0.0	-0.6	-1.5	-1.7	-1.2
Fasting Glucose	1.8	2.2	6.0	1.2	-1.5	-1.4	-1.5	-1.3	-2.4	-1.6	-1.4	-1.4	0.3	-1.4	-1.6	-1.5	-1.3
HbA1C	0.3	0.3	1.8	-0.4	0.1	0.1	-0.3	0.2	-0.2	0.2	0.1	-0.2	-0.8	-0.4	-0.9	-1.4	-0.5
HDL Cholesterol	0.3	0.5	2.5	0.5	-0.8	-0.7	-0.0	-0.4	0.2	-1.0	-0.7	-1.1	1.6	-0.2	-0.4	0.0	-0.4
LDL Cholesterol	7.1	11.2	19.2	2.7	-3.0	-3.1	-3.2	-2.8	-3.0	-3.8	-3.0	-4.3	0.8	-3.2	-4.3	-4.4	-3.6
Lupus	0.5	0.7	2.0	1.4	-0.9	-1.0	-1.4	-1.0	-0.7	0.1	-0.9	0.3	0.7	-0.9	-0.2	0.2	-0.7
Neuroticism (2016)	3.4	4.9	8.2	2.6	-2.7	-2.7	-2.6	-2.1	-0.9	-1.4	-2.7	-2.9	2.0	-2.4	-1.7	-1.4	-1.8
Primary Biliary Cirrhosis	0.9	1.3	3.3	1.3	-1.3	-1.3	-1.2	-1.6	-1.8	-0.1	-1.3	-0.4	1.1	-1.3	-0.4	0.2	-0.9
Rheumatoid Arthritis	0.9	1.2	2.5	1.0	-1.1	-1.1	-1.1	-1.3	-1.5	-1.6	-1.1	-1.0	0.7	-1.1	-1.0	-0.6	-1.0
Schizophrenia (2014)	0.3	0.7	3.1	0.4	-0.7	-0.6	0.0	-0.9	0.2	0.4	-0.7	0.8	1.5	-0.0	0.9	1.8	0.5
Triglycerides	3.2	5.3	8.9	1.9	-1.8	-1.9	-2.5	-1.8	-3.0	-2.6	-2.1	-2.8	0.1	-2.1	-2.8	-2.7	-2.7
Type 2 Diabetes (T2D) (2012)	5.0	5.7	10.9	2.5	-2.5	-2.4	-2.4	-2.4	-3.1	-3.3	-2.7	-1.6	2.4	-2.2	-1.8	-1.1	-2.2
Ulcerative Colitis	0.1	0.2	0.9	-0.1	-0.2	-0.1	-0.5	-0.6	-0.3	0.9	-0.2	0.1	-0.0	-0.7	-0.0	0.3	-0.1
Blood Eosinophil Count	2.3	17.5	30.8	4.5	-4.5	-4.5	-5.0	-4.1	-3.4	-2.1	-4.5	-5.5	2.5	-4.9	-4.3	-2.8	-4.3
Blood Platelet Count	2.2	25.8	51.4	3.6	-3.6	-3.5	-6.6	-3.5	-3.2	-5.0	-3.6	-7.1	-1.2	-5.5	-5.9	-7.2	-6.9
Blood Red Count	0.6	6.1	10.8	-2.9	2.8	3.0	2.4	2.2	1.1	1.0	2.8	3.3	-2.2	2.9	2.9	2.1	1.9
Blood White Count	1.0	7.2	10.6	2.9	-3.0	-3.0	-2.1	-3.3	-2.7	-1.9	-3.0	-2.8	3.0	-3.1	-2.7	-0.9	-2.1
Heel T-Score	2.0	16.2	54.8	-0.9	1.7	1.6	3.2	2.1	7.2	3.2	1.6	4.1	3.4	3.1	5.0	7.4	4.8
BMI	2.6	14.8	28.4	3.4	-3.5	-3.4	-4.9	-3.2	-5.3	-4.3	-3.4	-4.0	0.6	-4.1	-3.4	-4.0	-4.5
Height	1.5	29.0	95.1	-5.6	5.5	5.6	5.3	5.3	9.8	5.8	5.6	4.8	-3.3	5.0	3.8	2.2	4.4
Waist Hip Ratio (WHR)	0.7	3.2	9.0	1.3	-1.5	-1.6	-1.7	-1.0	-1.0	-0.8	-1.5	-2.9	-0.3	-1.7	-2.4	-3.0	-2.1
Systolic Blood Pressure	2.7	13.5	28.1	-3.6	3.5	3.5	5.3	3.3	1.3	3.7	3.5	4.5	-1.3	4.4	3.4	3.6	4.5
Smoking Status	6.5	15.5	29.2	4.1	-4.3	-4.4	-3.1	-3.8	-1.4	-2.8	-4.4	-4.2	3.8	-4.8	-5.4	-3.5	-3.5
Allergy or Eczema	2.1	5.5	9.1	3.0	-2.6	-2.6	-2.8	-2.7	-2.7	-1.4	-2.6	-2.3	2.8	-2.2	-0.9	0.8	-1.9
Cardiovascular Disease	0.9	2.8	10.2	1.2	-1.1	-1.2	-0.9	-1.2	-3.2	-2.0	-1.1	-1.7	0.3	-1.2	-2.4	-2.2	-1.8
Hypothyroidism (self reported)	0.3	0.8	3.6	-0.4	0.1	0.1	-0.0	0.4	-0.8	1.4	0.1	0.7	-0.6	-0.3	0.9	1.9	1.5
Respiratory disease	9.4	21.0	29.5	5.0	-5.0	-5.0	-5.4	-4.7	-3.1	-3.9	-5.1	-5.4	3.8	-5.4	-4.1	-2.4	-4.6
Type 2 Diabetes (T2D) (2018)	1.6	3.1	7.7	2.2	-2.1	-2.0	-1.6	-2.2	-2.8	-1.4	-2.1	-0.2	1.9	-1.7	-0.4	1.0	-0.5
Lung FEV1/FVC ratio	3.0	15.3	21.9	3.3	-3.8	-3.6	-4.6	-3.4	-4.5	-4.4	-3.7	-4.7	0.7	-4.0	-4.2	-4.3	-4.1
Lung FVC	3.0	15.5	23.1	-4.2	4.2	4.2	4.4	3.9	4.8	3.7	4.2	4.4	-2.4	4.4	3.4	2.2	3.6
Neuroticism	5.4	13.0	21.8	4.5	-4.3	-4.4	-2.6	-3.5	-2.6	-2.5	-4.3	-3.4	4.7	-3.2	-3.8	-2.3	-3.0
Chronotype (morning person)	0.6	1.4	6.8	-0.6	0.8	0.9	0.6	0.7	1.1	0.6	0.8	1.5	-0.0	0.7	2.0	2.6	1.4
Hair Pigment	0.0	0.8	2.2	0.8	-0.7	-0.6	-1.1	-0.5	0.1	-1.2	-0.7	-1.5	0.2	-0.8	-1.0	-1.1	-1.0
Tanning	0.2	2.0	8.2	1.4	-1.6	-1.6	-0.6	-1.3	0.7	0.7	-1.6	-0.6	2.9	-1.6	-1.7	-0.6	-0.7
Hand grip strength (left)	0.7	1.8	9.9	-0.6	0.4	0.4	1.5	0.4	3.1	0.4	0.4	1.9	1.3	0.6	0.8	1.6	1.6
Number of treatments/medications taken	1.9	3.5	8.0	1.9	-1.9	-1.9	-2.2	-1.8	-2.8	-1.6	-1.8	-2.0	0.8	-2.1	-1.7	-0.9	-1.7
Average weekly spirits intake	7.8	9.7	13.4	3.4	-3.7	-3.6	-3.2	-2.9	-1.3	-2.6	-3.6	-3.0	3.1	-3.5	-3.3	-2.5	-3.1
Sensitivity / hurt feelings	1.2	2.1	3.2	1.5	-1.8	-1.8	-1.0	-1.4	-0.5	-1.3	-1.8	-1.7	1.6	-1.3	-1.8	-1.3	-1.3
Frequency of depressed mood in last 2 weeks	6.6	9.3	14.8	3.7	-3.6	-3.7	-2.8	-3.1	-1.4	-2.1	-3.6	-3.1	3.8	-3.2	-3.1	-1.9	-2.3
Hearing difficulty/problems: Yes	1.0	1.5	5.0	0.4	-0.5	-0.5	-0.8	-0.2	-2.0	-1.6	-0.5	-1.2	-0.7	-0.8	-1.6	-2.2	-1.5
Relative age of first facial hair	0.8	1.7	7.7	1.3	-0.9	-1.0	0.5	-1.3	0.3	-0.3	-1.0	0.8	2.8	0.1	0.9	2.5	1.0
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	2.8	1.1	-1.3	-1.2	-1.7	-1.1	-1.1	-0.6	-1.2	-1.6	0.2	-1.3	-1.0	-0.7	-1.1
Ever used hormone-replacement therapy (HRT)	4.2	5.3	7.3	2.5	-2.4	-2.5	-2.2	-2.0	-1.7	-2.7	-2.5	-2.6	2.2	-2.5	-2.2	-1.5	-2.4
Ever had hysterectomy (womb removed)	2.3	2.6	4.4	1.7	-1.6	-1.6	-1.5	-1.6	-2.1	-1.6	-1.6	-1.4	1.5	-1.8	-1.8	-0.9	-1.7
Systolic blood pressure, automated reading	0.8	2.2	6.6	-1.4	1.3	1.2	2.6	1.4	1.0	1.2	1.4	1.8	0.1	1.7	1.1	1.6	1.9
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.0	0.5	-0.6	-0.6	-0.2	-0.4	-0.3	0.2	-0.6	0.9	0.6	-0.7	0.2	1.0	0.4
Angina	7.0	9.2	15.7	-3.6	3.6	3.5	3.2	3.9	1.9	3.1	3.6	2.2	-4.0	3.1	1.7	0.3	2.6
Medication for hormone replacement therapy	8.8	9.8	13.9	3.2	-3.4	-3.5	-3.2	-2.9	-3.1	-3.1	-3.5	-3.7	2.3	-3.4	-3.2	-2.1	-2.6
Vitamin and mineral supplements	1.8	2.4	4.7	-1.2	1.1	1.1	2.0	1.2	0.5	1.6	1.1	2.2	-0.2	1.9	1.7	1.9	2.1
Supplements: Zinc	0.3	0.3	1.4	-0.5	0.3	0.3	0.0	0.9	0.6	0.5	0.3	-0.2	-0.8	-0.2	-0.4	-1.2	-0.2
Medication: Co-codamol	0.3	0.3	1.1	0.7	-0.5	-0.6	-0.5	-0.1	0.3	-0.6	-0.5	-1.0	0.9	-0.3	-0.3	-0.1	-0.3
Medication: Metformin	1.9	2.7	4.8	2.0	-1.9	-1.9	-2.1	-2.2	-0.7	-1.6	-1.9	-1.2	1.5	-2.0	-1.0	-0.0	-1.4
Diabetes (father)	0.6	0.7	1.8	-0.8	0.9	0.9	1.0	1.0	-0.2	1.4	1.0	1.0	-0.6	0.8	0.4	0.1	0.5
Diabetes (mother)	2.3	3.0	5.3	2.2	-2.1	-2.1	-1.5	-2.0	-2.3	-1.3	-2.1	-1.0	2.3	-1.6	-0.6	0.6	-0.8
Severe depression (siblings)	0.2	0.2	0.7	-0.1	0.2	0.1	0.7	0.5	0.7	0.7	0.2	0.2	0.3	0.4	-0.2	0.1	0.8
Pack years adult smoking proportion	4.6	7.0	9.9	3.1	-3.1	-3.1	-3.1	-3.0	-2.4	-2.6	-3.1	-2.4	2.5	-3.0	-1.9	-1.0	-1.9
Impedance of leg (right)	0.1	0.4	4.2	0.2	-0.1	-0.1	0.3	-0.0	2.0	-0.2	-0.1	-0.4	1.0	-0.0	-0.4	0.0	0.4
Leg fat-free mass (left)	0.1	0.7	2.9	-1.1	1.0	1.1	0.3	1.0	0.2	0.6	1.0	0.9	-1.7	0.5	0.4	-0.7	0.2
Trunk fat percentage	1.9	7.6	12.6	2.6	-2.7	-2.7	-3.2	-2.3	-2.5	-3.1	-2.6	-3.5	1.2	-2.9	-2.7	-2.6	-2.9
Hand grip strength (right)	0.9	2.5	9.8	-0.8	0.8	0.9	1.7	0.4	3.1	0.5	0.8	2.2	1.0	1.0	1.6	2.5	1.9
Townsend deprivation index at recruitment	10.7	15.0	23.1	3.8	-4.0	-4.0	-4.0	-3.4	-3.4	-4.0	-4.0	-4.8	2.4	-3.8	-4.2	-3.9	-4.0
Current tobacco smoking	11.6	19.0	26.5	4.9	-4.8	-4.9	-4.5	-4.5	-2.2	-3.3	-4.8	-4.8	3.8	-5.2	-4.9	-3.5	-3.9
Average weekly fortified wine intake	0.1	0.1	0.3	-0.1	0.3	0.3	-0.5	-0.2	0.1	-0.5	0.2	-0.1	-0.3	0.0	0.4	0.5	-0.1
Maternal smoking around birth	4.0	5.8	10.1	2.9	-2.9	-2.9	-2.2	-2.7	-1.2	-2.2	-2.9	-2.3	3.2	-2.4	-2.1	-0.6	-1.6
Fed-up feelings	4.6	8.3	13.6	3.5	-3.6	-3.7	-2.5	-2.8	-2.8	-1.6	-3.6	-2.7	3.3	-3.0	-2.7	-1.2	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	4.0	5.3	10.6	2.3	-2.5	-2.5	-2.0	-2.0	-0.7	-1.2	-2.5	-3.3	1.9	-2.6	-3.1	-2.5	-1.9
Relative age voice broke	0.5	0.8	3.3	0.8	-0.5	-0.5	0.2	-0.8	1.8	0.2	-0.5	0.2	1.8	0.1	0.8	1.6	0.5
Taking other prescription medications	4.1	6.3	10.2	3.0	-2.9	-2.9	-3.2	-2.8	-2.4	-2.0	-2.9	-2.5	2.3	-2.9	-1.3	0.1	-2.1
Age when periods started (menarche)	3.7	8.8	27.3	-2.6	2.5	2.5	3.2	2.5	5.2	2.6	2.5	2.7	-0.8	2.8	2.8	3.3	3.6
Bilateral oophorectomy (both ovaries removed)	3.6	4.1	6.3	2.1	-2.2	-2.2	-1.8	-2.1	-2.1	-2.0	-2.1	-2.5	2.0	-1.8	-1.9	-1.3	-2.1
Heel bone mineral density (BMD) T-score, automated (left)	2.5	5.6	15.3	-1.1	1.2	1.1	2.1	1.7	3.5	2.2	1.2	3.1	1.2	1.8	2.9	3.9	3.2
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	2.9	0.9	-0.6	-0.7	-0.3	-0.8	-0.4	0.5	-0.6	0.4	1.2	-0.6	0.8	1.7	0.6
Qualifications: CSEs or equivalent	2.2	2.9	6.5	1.9	-1.8	-1.7	-2.5	-2.0	-2.5	-1.7	-1.8	-1.2	1.1	-1.9	-0.4	0.3	-1.5
Serious illness, injury or assault to yourself	0.6	0.7	1.2	1.1	-0.8	-0.8	-1.0	-0.7	-1.0	0.6	-0.8	-1.1	0.4	-1.0	-0.8	-0.7	-0.7
High blood pressure	0.3	0.8	1.6	-0.9	0.9	0.8	1.3	1.0	-0.9	-0.6	0.9	0.4	-1.1	0.8	-0.7	-1.2	0.1
Hayfever, allergic rhinitis or eczema	2.0	4.4	7.7	2.7	-2.4	-2.4	-2.3	-2.4	-2.7	-0.9	-2.4	-1.6	2.8	-2.0	-0.5	1.2	-1.4
Multivitamins +/- minerals	2.0	2.6	5.0	1.5	-1.4	-1.4	-2.2	-1.6	0.0	-1.9	-1.5	-2.2	0.9	-1.9	-1.2	-1.2	-2.0
Stomach or abdominal pain in last month	5.9	7.4	12.2	2.9	-2.9	-2.8	-3.5	-2.6	-1.1	-2.5	-2.8	-3.1	1.8	-3.0	-2.7	-2.0	-3.3
Supplements: Glucosamine	0.7	0.9	2.4	1.0	-1.0	-1.0	-1.5	-0.8	-1.0	-0.9	-1.0	-1.2	0.7	-1.2	-0.3	-0.1	-0.9
Diverticular disease/diverticulitis (self-reported)	11.5	13.7	24.8	3.3	-3.5	-3.4	-4.2	-3.3	-1.4	-3.7	-3.4	-4.8	1.8	-4.0	-4.2	-4.0	-5.0
Medication: Atenolol	6.6	8.3	16.3	-3.3	3.5	3.5	2.7	3.8	0.8	2.5	3.6	2.5	-4.0	3.0	1.8	0.3	2.1
Medication: Levothyroxine sodium	0.5	0.9	4.2	-0.4	0.3	0.3	0.3	0.8	-0.8	1.2	0.3	0.8	-0.4	0.0	1.2	2.0	1.5
Sitting height	3.3	23.6	28.9	-5.4	5.3	5.4	4.9	4.7	5.3	5.0	5.3	5.1	-3.6	4.8	4.5	3.5	4.7
Chronic bronchitis/emphysema (father)	5.0	5.9	9.5	2.6	-2.6	-2.6	-3.1	-2.1	-1.1	-2.1	-2.6	-3.0	1.8	-2.6	-2.2	-2.1	-2.6
High blood pressure (mother)	0.4	0.5	2.7	-0.3	0.4	0.4	0.4	0.3	-1.6	-0.2	0.4	0.7	-0.7	0.5	-0.6	-1.4	-0.4
Body mass index (BMI)	2.3	9.6	17.6	2.8	-2.8	-2.8	-3.8	-2.4	-4.2	-3.5	-2.8	-3.3	0.6	-3.3	-2.8	-3.3	-3.6
Impedance of leg (left)	0.1	0.7	4.8	0.6	-0.5	-0.6	-0.2	-0.4	2.2	-0.1	-0.5	-1.1	1.3	-0.4	-0.6	-0.1	0.1
Leg predicted mass (left)	0.1	0.7	2.8	-1.1	1.0	1.0	0.3	1.0	0.3	0.6	1.0	0.8	-1.7	0.5	0.3	-0.7	0.2
Trunk fat mass	1.2	5.0	8.4	2.0	-2.1	-2.1	-2.7	-1.7	-1.9	-2.5	-2.0	-2.9	0.6	-2.4	-2.4	-2.6	-2.6
Waist circumference	3.0	11.2	19.6	2.9	-3.0	-3.0	-4.1	-2.4	-3.3	-2.8	-3.0	-4.1	0.4	-3.6	-3.6	-4.4	-4.1
Number of incorrect matches in round	1.2	2.0	3.5	-1.4	1.5	1.5	1.4	1.4	1.5	1.9	1.5	1.2	-1.2	1.7	1.6	0.8	1.1
Past tobacco smoking	2.5	4.5	10.4	-2.1	2.4	2.4	1.0	1.7	0.7	1.8	2.4	1.8	-2.5	2.3	3.2	2.1	2.1
Alcohol usually taken with meals	3.5	5.7	9.1	-2.8	3.0	3.0	1.9	2.6	1.6	1.5	2.9	1.6	-2.9	2.7	2.5	1.8	1.7
Nervous feelings	0.2	0.4	2.0	0.8	-0.6	-0.7	0.4	-0.3	-0.6	0.0	-0.6	-0.2	1.4	0.3	-0.2	0.5	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	1.8	1.1	-1.1	-1.1	-0.8	-0.5	-1.1	-0.4	-1.0	-1.2	0.9	-1.0	-1.4	-1.2	-0.6
Hearing difficulty/problems with background noise	4.2	6.6	11.6	2.3	-2.4	-2.4	-2.8	-2.0	-2.4	-2.6	-2.5	-3.4	1.1	-2.5	-2.9	-3.0	-3.0
Hair/balding pattern: Pattern 2	0.6	0.7	3.2	0.6	-0.6	-0.6	-0.7	-0.4	1.8	-0.1	-0.6	-1.1	0.4	-1.2	-0.9	-1.1	-0.4
Had menopause	0.9	1.1	2.5	1.3	-1.2	-1.3	-0.8	-0.9	-0.5	-0.7	-1.2	-1.6	1.5	-1.2	-0.8	-0.1	-0.5
Had other major operations	0.7	0.9	2.7	-1.1	1.1	1.1	0.3	1.2	-0.8	1.0	1.1	0.5	-1.6	0.8	0.8	0.2	0.3
Forced vital capacity (FVC)	4.3	16.7	27.8	-4.0	4.0	4.0	4.3	3.1	5.3	4.4	3.9	5.1	-1.2	4.0	4.2	4.0	4.2
Heel bone mineral density (BMD) T-score, automated (right)	2.8	6.4	15.3	-1.4	1.6	1.6	2.1	1.9	3.5	2.0	1.6	3.6	0.4	2.3	3.4	3.9	3.3
Ever unenthusiastic/disinterested for a whole week	2.4	2.9	5.4	2.0	-2.0	-2.0	-2.0	-1.9	-0.3	-0.4	-2.1	-1.8	1.8	-2.3	-1.5	-0.6	-1.4
Qualifications: None of the above	1.6	3.5	5.5	2.0	-2.3	-2.3	-1.4	-2.0	-0.7	-0.8	-2.3	-2.0	2.3	-2.1	-2.3	-1.1	-1.2
Financial difficulties in last 2 years	2.5	3.3	5.0	2.2	-2.0	-2.0	-2.2	-1.8	-2.2	-1.8	-2.0	-1.4	1.4	-2.0	-1.2	-0.7	-1.6
Mouth/teeth dental problems	0.3	0.5	2.2	-0.9	0.7	0.7	1.5	0.3	0.1	-0.4	0.7	0.1	-0.5	1.0	-0.4	-0.3	0.7
Heart attack	13.0	16.6	24.8	-4.7	4.7	4.7	4.5	5.0	2.4	4.5	4.7	3.5	-4.8	4.3	2.7	0.6	3.6
Allergy	3.5	8.0	11.2	-3.3	3.2	3.2	3.2	3.0	3.1	1.5	3.2	3.0	-2.8	3.2	2.1	0.5	2.5
Pain all over the body in last month	0.7	0.8	3.4	-0.6	0.7	0.7	0.8	0.9	1.9	1.2	0.7	1.0	-0.2	0.6	0.5	0.7	0.9
Diabetes (self-reported)	1.3	2.0	3.5	1.8	-1.7	-1.7	-1.2	-1.7	-1.8	-0.9	-1.7	-0.1	1.9	-1.4	-0.4	1.2	-0.3
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.2	0.3	-0.1	-0.1	-0.3	0.1	-1.1	-0.6	-0.1	-0.3	-0.2	0.1	0.6	0.6	-0.1
Medication: Ramipril	1.9	2.4	5.3	-1.9	1.7	1.7	1.2	1.8	0.4	1.6	1.7	1.4	-2.3	1.3	0.9	0.6	2.0
Medication: Simvastatin	2.3	3.4	15.4	1.0	-1.1	-1.1	-1.1	-1.3	-3.9	-1.8	-1.1	-1.8	-0.4	-1.3	-2.7	-2.4	-1.8
Fluid intelligence score	0.2	0.5	2.2	-0.4	0.4	0.4	-0.6	0.0	-1.3	0.1	0.4	0.1	-1.5	-0.3	-0.3	-1.1	-0.9
Illnesses of siblings	1.3	1.9	6.5	-1.4	1.4	1.5	1.2	1.4	2.5	1.6	1.4	1.4	-0.7	0.9	0.8	0.4	1.2
Neuroticism score	4.8	9.9	14.8	3.8	-3.7	-3.8	-2.6	-2.9	-1.7	-2.6	-3.8	-3.3	3.9	-2.7	-3.2	-2.4	-2.8
Weight	0.2	1.0	3.2	0.6	-0.6	-0.6	-1.5	-0.4	-0.7	-0.9	-0.6	-1.2	-0.6	-1.2	-1.0	-1.8	-1.4
Impedance of arm (right)	0.7	3.4	8.9	2.0	-2.1	-2.1	-1.1	-2.2	-0.0	-1.1	-2.1	-2.3	3.0	-1.6	-1.9	-0.5	-1.3
Arm fat percentage (right)	4.6	18.2	26.4	4.1	-4.2	-4.2	-4.8	-3.8	-5.1	-4.5	-4.2	-4.8	2.0	-4.4	-4.1	-4.0	-4.7
Trunk fat-free mass	0.5	3.0	5.0	-2.1	2.0	2.1	1.3	1.9	2.0	1.7	2.0	1.9	-2.2	1.5	1.2	-0.0	1.1
Hip circumference	1.0	4.3	9.4	1.9	-1.9	-1.9	-3.1	-1.7	-1.9	-1.8	-1.9	-2.2	0.4	-2.5	-1.9	-2.3	-2.5
Time employed in main current job	1.8	2.0	7.0	-1.7	1.2	1.2	1.3	1.4	2.6	1.7	1.2	1.2	-0.8	1.2	1.1	0.8	1.6
Alcohol intake versus 10 years previously	1.4	2.2	7.7	0.9	-0.9	-0.9	-1.1	-0.9	-2.4	-1.0	-0.9	-1.3	-0.4	-1.2	-2.1	-2.8	-1.7
Father’s age at death	0.6	0.8	3.3	1.0	-1.0	-0.9	-0.5	-1.1	-0.2	-1.0	-1.0	0.0	1.8	-0.7	-0.1	0.2	-0.9
Worrier / anxious feelings	0.1	0.2	0.9	0.3	-0.1	-0.2	0.7	0.2	0.2	-0.1	-0.1	0.5	1.0	0.7	0.2	0.8	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	3.1	1.3	-1.3	-1.4	-1.2	-0.7	-1.7	0.3	-1.3	-1.8	0.8	-1.2	-1.4	-1.3	-0.8
Falls in the last year	8.0	10.9	18.1	3.4	-3.3	-3.4	-3.5	-3.0	-1.3	-1.9	-3.3	-4.2	2.1	-4.0	-4.1	-3.6	-3.5
Hair/balding pattern: Pattern 3	2.0	2.9	8.3	-1.1	1.4	1.4	1.4	1.4	-0.8	0.3	1.4	2.3	-0.5	2.1	2.8	2.9	1.7
Number of live births	0.1	0.2	1.1	-0.3	0.3	0.3	0.4	0.4	1.0	0.5	0.3	0.6	0.1	0.3	0.4	0.5	0.3
Forced expiratory volume in 1-second (FEV1)	2.4	8.1	14.1	-2.9	2.8	2.9	3.0	2.1	3.5	3.0	2.8	3.8	-1.0	2.8	2.9	2.6	2.9
Pulse rate	2.0	3.4	5.0	-1.8	1.9	1.9	1.1	1.9	1.8	1.6	1.9	1.7	-2.1	1.4	2.2	1.7	2.2
Happiness	0.9	1.1	2.5	1.2	-1.3	-1.3	-0.4	-1.4	-1.2	-0.4	-1.3	-0.3	1.6	-1.0	-1.0	-0.4	-0.3
Noisy workplace	4.2	5.2	12.0	1.6	-1.8	-1.8	-2.4	-1.7	-2.9	-2.3	-1.8	-2.5	0.2	-2.3	-2.9	-3.5	-2.5
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.3	-1.1	1.3	1.4	0.8	0.7	0.4	0.1	1.3	1.4	-1.4	1.8	1.0	-0.7	-0.1
Serious illness, injury or assault of a close relative in last 2 years	3.2	3.7	5.2	-1.9	2.2	2.1	2.0	2.0	0.7	1.7	2.2	2.0	-1.7	2.3	2.2	1.7	1.5
Mouth/teeth dental problems: Dentures	0.5	0.8	1.6	-0.7	1.0	1.0	0.2	1.3	1.2	1.2	1.0	0.9	-1.2	0.4	0.9	0.2	0.5
Asthma	5.9	11.7	16.3	4.0	-4.0	-4.0	-3.8	-3.4	-2.0	-2.5	-4.0	-4.0	3.5	-4.0	-2.8	-1.3	-3.1
Medication: Ibuprofen (e.g. Nurofen)	3.0	3.8	5.2	2.0	-2.1	-2.1	-2.1	-2.1	-1.8	-1.5	-2.1	-1.5	1.8	-2.3	-2.0	-1.5	-2.0
Medication: Cholesterol lowering	0.7	1.2	10.9	0.1	-0.2	-0.2	0.1	-0.3	-3.3	-1.2	-0.2	-0.6	-0.8	0.1	-1.2	-1.1	-0.4
Depression (self-reported)	0.2	0.2	0.7	0.6	-0.3	-0.3	-0.2	0.1	-0.1	-0.4	-0.3	0.1	0.9	0.1	0.5	0.8	0.4
Medication: Lansoprazole	0.4	0.4	0.9	0.6	-0.7	-0.6	-0.8	-0.9	-0.7	-0.7	-0.6	-0.6	0.6	-0.4	-0.5	-0.5	-0.9
Prospective memory result	0.9	1.1	2.4	-0.6	0.6	0.6	1.5	1.0	1.5	1.3	0.6	1.4	0.7	0.8	0.6	1.1	1.3
Lung cancer (father)	2.8	3.2	5.9	1.6	-1.8	-1.8	-2.3	-1.2	-2.2	-2.0	-1.8	-2.4	0.6	-2.2	-1.6	-1.3	-1.7
Illnesses of mother	0.2	0.2	1.3	-0.2	0.2	0.2	-0.2	-0.0	1.2	-0.0	0.1	0.1	0.2	-0.0	0.8	1.0	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.4	7.6	13.5	-2.9	2.9	3.0	2.7	2.3	3.4	2.6	2.9	3.7	-1.6	2.8	2.6	1.9	2.5
Pulse wave Arterial Stiffness index	1.6	1.8	2.9	1.7	-1.6	-1.7	-1.1	-1.5	-0.5	-0.7	-1.7	-1.0	1.7	-1.6	-1.2	-0.7	-1.4
Impedance of arm (left)	0.3	1.3	5.4	1.3	-1.2	-1.3	-0.4	-1.3	0.6	-0.6	-1.2	-1.4	2.3	-0.7	-0.8	0.5	-0.4
Arm fat mass (right)	2.0	8.2	11.8	2.6	-2.7	-2.7	-3.4	-2.3	-3.3	-3.0	-2.7	-3.2	0.9	-3.1	-2.8	-3.1	-3.3
Trunk predicted mass	0.5	2.9	4.8	-2.1	2.0	2.0	1.2	1.9	2.0	1.7	1.9	1.8	-2.2	1.4	1.1	-0.1	1.1
Standing height	1.8	18.2	53.1	-4.3	4.3	4.3	4.4	3.9	7.3	4.8	4.2	3.9	-2.2	4.0	3.3	2.7	4.1
Length of working week for main job	0.5	0.6	2.7	-0.4	0.6	0.5	0.2	0.6	-1.2	-0.5	0.5	-0.4	-1.0	0.1	-0.7	-1.6	-0.8
Exposure to tobacco smoke at home	8.0	9.0	13.5	2.7	-3.0	-2.9	-3.4	-3.3	-1.8	-2.5	-3.0	-3.7	1.8	-3.2	-3.5	-3.1	-3.1
Breastfed as a baby	0.1	0.2	0.6	-0.3	0.2	0.2	0.8	0.6	0.1	0.3	0.3	0.1	-0.0	0.5	-0.2	0.2	0.7
Tense / ‘highly strung’	0.4	0.6	1.9	0.8	-0.7	-0.7	-0.2	-0.0	0.9	-0.6	-0.7	-1.0	1.4	-0.3	-0.9	-0.7	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	2.8	4.3	5.5	2.1	-2.1	-2.1	-2.3	-2.0	-2.2	-2.1	-2.1	-2.2	1.7	-2.0	-2.0	-1.7	-2.3
Hair/balding pattern: Pattern 4	1.0	2.5	13.9	1.2	-1.5	-1.4	-1.3	-1.3	-3.7	-1.0	-1.5	-1.1	0.1	-1.2	-1.5	-1.5	-1.6
Birth weight of first child	0.3	0.6	1.5	0.6	-0.8	-0.7	-0.6	-1.0	-0.1	-0.6	-0.8	-1.2	0.8	-0.4	-0.7	-0.4	-1.0
Peak expiratory flow (PEF)	0.5	1.1	4.6	-0.1	0.1	0.1	0.7	-0.6	1.6	0.6	0.1	1.3	1.3	0.4	1.3	2.1	1.1
Pulse wave reflection index	13.4	16.6	21.4	4.0	-4.4	-4.4	-3.7	-4.6	-3.4	-3.3	-4.4	-3.9	3.5	-4.4	-4.6	-3.7	-4.3
Ever highly irritable/argumentative for 2 days	1.5	1.8	4.2	1.4	-1.5	-1.5	-1.4	-1.8	-0.2	-0.6	-1.6	-0.7	1.7	-2.1	-1.2	-0.4	-1.1
Loud music exposure frequency	0.8	0.8	2.6	0.5	-0.9	-0.8	0.1	-0.8	-1.6	-0.8	-0.8	-0.3	0.7	-0.2	-1.4	-1.5	-0.8
Qualifications: O levels/GCSEs or equivalent	2.0	3.2	4.8	-1.8	2.2	2.2	1.8	1.8	1.9	0.9	2.2	1.8	-1.7	2.2	1.8	0.9	1.2
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.9	0.7	-0.8	-0.7	-0.9	-0.7	0.3	0.5	-0.7	-0.1	0.9	-0.9	0.2	0.3	-0.4
Blood clot in the leg (DVT)	0.6	0.8	1.9	-1.0	0.7	0.8	1.0	0.4	1.2	1.4	0.8	0.8	-0.3	0.8	0.8	0.7	1.0
Medication: Paracetamol	6.1	10.1	17.4	3.1	-3.3	-3.3	-3.6	-2.8	-4.2	-3.0	-3.3	-3.2	1.5	-3.6	-3.4	-2.5	-3.1
Headache pain in last month	8.5	14.6	20.0	4.5	-4.4	-4.3	-4.4	-4.4	-2.3	-4.2	-4.4	-3.4	3.9	-4.0	-2.8	-1.3	-3.7
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	3.8	1.0	-0.9	-0.9	-1.0	-0.7	2.0	0.2	-0.9	-0.6	1.6	-1.0	0.2	0.5	-0.4
Glaucoma (self-reported)	2.2	2.6	4.8	-1.8	1.8	1.9	1.2	1.5	2.2	2.2	1.8	1.0	-1.9	1.6	1.0	0.4	1.3
Gout (self-reported)	0.7	0.9	4.8	0.6	-0.7	-0.7	-1.1	-1.1	-2.2	-0.8	-0.7	-0.7	-0.5	-0.6	-0.5	-0.7	-1.0
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	4.7	-0.8	0.5	0.5	0.3	0.9	-0.3	1.3	0.6	0.9	-0.9	-0.0	1.4	2.2	1.8
Medication: Amlodipine	0.8	1.2	6.7	0.4	-0.3	-0.3	-0.4	-0.6	-0.7	-0.5	-0.3	-0.7	-0.4	-0.8	-2.0	-2.6	-1.6
Medication: Ventolin 100micrograms inhaler	3.8	4.9	6.6	2.3	-2.4	-2.5	-2.3	-2.3	-0.8	-2.1	-2.5	-2.4	1.8	-2.6	-2.3	-1.6	-2.3
Birth weight	0.6	1.2	6.5	0.4	-0.4	-0.4	-1.0	0.1	-0.5	-0.7	-0.4	-1.5	-0.5	-0.6	-1.5	-2.5	-1.7
Chronic bronchitis/emphysema (mother)	4.5	5.3	11.2	2.0	-1.7	-1.8	-2.3	-1.5	-2.5	-1.2	-1.7	-2.9	0.3	-2.6	-3.3	-3.2	-2.9
High blood pressure (siblings)	1.2	1.8	5.0	1.3	-1.4	-1.4	-1.0	-1.3	-2.2	-1.5	-1.3	-1.2	0.8	-1.0	-1.3	-1.1	-1.2
Forced vital capacity (FVC), Best measure	4.5	16.3	26.2	-4.2	4.2	4.2	4.2	3.5	5.0	4.2	4.2	5.1	-2.1	4.0	3.7	2.9	3.9
Body fat percentage	2.7	10.7	15.8	3.1	-3.2	-3.2	-3.9	-2.7	-3.4	-3.7	-3.1	-4.0	1.3	-3.5	-3.3	-3.2	-3.6
Leg fat percentage (right)	4.1	14.7	21.2	3.4	-3.5	-3.5	-4.5	-2.9	-4.2	-4.4	-3.4	-4.6	1.0	-4.0	-4.0	-4.3	-4.3
Arm fat-free mass (right)	0.7	3.7	7.2	-2.3	2.2	2.3	1.3	2.3	2.1	1.6	2.3	1.9	-2.7	1.5	1.4	0.0	1.3
Exposure to tobacco smoke outside home	3.2	4.3	8.0	1.7	-1.9	-1.8	-2.7	-1.8	-2.7	-1.6	-1.8	-2.8	0.2	-2.4	-2.0	-2.1	-2.2
Comparative body size at age 10	0.9	2.4	5.0	-1.5	1.7	1.7	1.5	1.1	-0.5	-0.4	1.7	2.1	-0.9	2.0	2.2	1.7	1.0
Number of full brothers	2.9	3.7	7.6	1.9	-2.0	-2.0	-2.0	-1.9	-1.9	-0.9	-2.0	-2.8	1.1	-2.0	-2.3	-1.7	-1.8
Worry too long after embarrassment	2.3	3.9	8.2	1.8	-1.9	-2.0	-1.3	-1.6	-1.2	-1.3	-2.0	-2.6	1.4	-1.6	-2.9	-2.8	-2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	2.3	3.0	4.2	1.9	-1.8	-1.8	-2.0	-1.8	-2.0	-1.9	-1.9	-1.4	1.7	-2.0	-1.4	-0.7	-1.6
Wheeze or whistling in the chest in last year	10.0	17.8	21.4	4.6	-4.6	-4.6	-4.5	-4.3	-3.8	-3.4	-4.6	-4.2	3.5	-4.6	-4.2	-3.1	-4.6
Number of children fathered	0.3	0.3	1.8	-0.3	0.3	0.3	-0.4	0.5	-0.0	-1.4	0.3	-0.7	-0.9	0.2	-0.1	-0.6	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.7	3.8	-1.3	1.6	1.5	1.2	1.9	0.5	0.8	1.6	0.6	-1.5	1.6	1.4	0.8	0.5
Age at first live birth	1.9	3.4	5.8	-2.4	2.1	2.2	1.5	1.7	2.4	1.7	2.1	2.0	-2.4	1.7	0.7	-0.3	0.8
Pulse wave peak to peak time	2.3	2.7	4.2	-2.0	2.0	2.0	1.4	1.8	1.1	1.0	2.0	1.2	-1.9	1.9	1.4	0.8	1.6
Health satisfaction	0.9	1.1	5.5	0.6	-0.8	-0.8	-1.0	-1.1	-2.3	-0.4	-0.8	-1.2	0.0	-0.7	-1.0	-1.3	-1.1
Shortness of breath walking on level ground	2.1	2.5	4.5	1.6	-1.6	-1.6	-1.3	-1.4	-0.8	-1.7	-1.6	-2.1	1.1	-1.6	-1.8	-1.5	-1.8
Qualifications: College or University degree	0.7	2.3	3.3	-1.7	1.8	1.8	1.4	1.7	1.6	0.7	1.8	1.7	-1.6	1.6	1.3	0.6	1.2
Eye problems/disorders: None of the above	0.9	1.0	5.5	0.7	-0.2	-0.3	0.3	-0.3	-0.8	0.0	-0.3	0.4	1.6	0.6	1.7	2.3	1.0
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.7	-0.3	0.4	0.3	0.0	0.6	-0.7	0.4	0.4	0.2	-0.5	-0.2	-0.4	-0.9	-0.2
Emphysema/chronic bronchitis	3.8	4.3	10.4	1.9	-1.8	-1.9	-2.1	-1.5	-1.3	-1.1	-1.8	-2.1	0.5	-2.6	-3.0	-3.2	-2.6
Medication for pain relief, constipation, heartburn	3.5	6.0	8.1	-2.5	2.4	2.5	2.4	2.2	2.6	2.7	2.4	2.6	-1.6	2.4	2.8	2.4	2.6
Neck or shoulder pain in last month	1.4	2.0	3.3	1.7	-1.6	-1.5	-1.8	-1.3	-1.7	-1.8	-1.5	-1.4	1.4	-0.9	-0.1	0.2	-1.1
Medication: Blood pressure	3.8	6.7	10.0	-3.1	3.0	3.0	3.2	3.1	-0.1	2.0	3.0	2.8	-3.1	2.8	1.3	0.3	2.4
Angina (self-reported)	7.1	9.3	14.7	-3.6	3.6	3.5	3.2	3.8	1.8	3.1	3.6	2.4	-3.8	3.2	1.9	0.6	2.7
Migraine (self-reported)	7.7	9.6	13.5	3.4	-3.5	-3.5	-3.6	-3.0	-0.9	-2.3	-3.5	-3.7	2.2	-3.7	-3.4	-2.6	-2.9
Medication: Ibuprofen	2.5	3.0	4.0	2.0	-1.9	-1.9	-1.8	-2.0	-1.2	-1.5	-1.9	-1.4	1.8	-2.0	-1.8	-1.2	-1.7
Medication: Allopurinol	0.3	0.4	3.1	-0.3	0.2	0.3	-0.1	-0.1	-1.8	0.1	0.3	0.5	-1.1	0.4	0.7	0.3	0.0
Medication: Omeprazole	0.3	0.3	1.6	-0.3	0.2	0.2	0.0	0.5	0.3	-0.9	0.2	-0.5	-0.3	0.3	-0.6	-1.3	-1.0
Medication: Seretide 50 evohaler	1.7	2.0	3.6	1.6	-1.4	-1.4	-1.5	-1.2	-0.9	-0.1	-1.3	-1.6	1.2	-1.9	-1.9	-1.1	-1.7
Mean time to correctly identify matches	1.1	2.1	7.5	-1.3	1.6	1.5	1.1	1.6	2.7	1.3	1.6	1.0	-1.4	1.4	1.2	0.6	1.0
Heart disease (mother)	2.5	3.0	4.1	-1.8	1.9	1.9	1.7	1.6	-0.1	1.6	2.0	1.9	-1.9	2.0	2.0	1.0	1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	7.3	1.2	-1.4	-1.4	-0.1	-1.4	-0.2	-0.7	-1.3	0.1	2.7	-0.9	-0.5	1.0	0.2
Whole body fat mass	1.3	5.6	8.4	2.1	-2.2	-2.2	-2.9	-1.9	-2.3	-2.6	-2.2	-2.8	0.6	-2.6	-2.5	-2.7	-2.7
Leg fat mass (right)	2.0	7.6	12.7	2.3	-2.3	-2.3	-3.4	-2.0	-3.0	-3.2	-2.3	-3.1	0.2	-3.0	-2.9	-3.6	-3.2
Arm predicted mass (right)	0.9	4.6	7.7	-2.5	2.5	2.5	1.6	2.5	2.2	1.8	2.5	2.3	-2.8	1.8	1.7	0.3	1.6
Pulse rate, automated reading	0.4	1.3	4.3	-1.3	1.3	1.3	0.5	1.5	0.9	0.9	1.3	0.4	-2.1	0.7	1.0	0.6	1.2
Alcohol intake frequency.	1.8	4.2	8.7	2.2	-2.0	-2.0	-3.0	-2.0	-2.8	-1.7	-2.0	-1.9	0.7	-2.3	-1.4	-1.5	-2.3
Comparative height size at age 10	0.3	1.7	8.5	-1.5	1.4	1.4	0.9	1.2	2.9	1.6	1.4	0.3	-1.1	0.7	0.1	-0.4	0.5
Number of full sisters	7.6	9.3	14.3	2.9	-3.2	-3.2	-2.9	-2.6	-3.1	-2.5	-3.2	-3.2	1.9	-3.2	-3.8	-3.7	-2.9
Suffer from ‘nerves’	1.7	2.7	4.9	2.1	-1.9	-1.9	-1.5	-1.3	-0.8	-1.6	-1.9	-2.2	1.8	-1.4	-1.6	-1.2	-1.4
Overall health rating	2.4	5.1	10.5	1.9	-2.0	-2.0	-2.5	-1.5	-2.4	-1.7	-1.9	-3.0	0.6	-2.0	-2.8	-3.2	-2.6
Chest pain or discomfort	0.9	1.2	2.5	1.2	-1.0	-1.1	-1.4	-0.9	-0.4	-0.6	-1.0	-1.6	0.3	-1.1	-1.2	-1.3	-1.4
Had major operations	0.3	0.4	1.5	0.3	-0.4	-0.3	-0.9	-0.2	-0.3	-0.5	-0.3	-1.2	-0.3	-0.4	-0.5	-0.9	-1.1
Age at last live birth	2.0	2.9	4.6	-2.1	2.1	2.1	1.8	1.9	2.0	0.9	2.0	1.7	-2.0	1.9	1.0	0.0	0.9
Family relationship satisfaction	0.4	0.5	1.3	0.8	-0.9	-0.9	-0.4	-0.8	-0.0	0.3	-0.9	-0.5	1.1	-0.8	-0.5	-0.1	-0.2
Leg pain on walking	0.1	0.1	0.9	-0.2	0.0	0.0	0.2	-0.2	0.2	0.9	0.1	-0.3	-0.1	-0.1	-0.0	0.2	0.4
Qualifications: NVQ or HND or HNC or equivalent	2.1	2.5	5.5	2.0	-2.1	-2.1	-1.3	-1.6	-1.2	-1.4	-2.1	-1.3	2.3	-1.3	-0.7	0.2	-0.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.2	-1.0	1.1	1.1	0.6	0.9	0.4	0.3	1.2	0.5	-1.5	1.1	1.1	0.1	0.5
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.9	-1.1	0.8	0.8	1.4	0.5	0.9	-0.2	0.8	0.8	-0.3	1.0	0.3	0.4	0.8
Medication: Aspirin	1.2	1.6	2.7	-1.5	1.5	1.5	1.4	1.4	1.1	1.1	1.5	0.8	-1.6	1.3	0.2	0.3	1.2
Supplements: Vitamin C	0.3	0.4	1.2	-0.7	0.6	0.6	0.2	0.3	0.0	1.1	0.6	0.2	-0.8	-0.1	-0.5	-1.0	-0.4
Knee pain experienced in last month	6.4	10.0	15.4	3.3	-3.3	-3.4	-3.3	-2.9	-2.1	-2.7	-3.3	-3.9	2.3	-3.6	-3.4	-2.8	-3.4
Hypertension (Self-reported)	0.5	1.5	2.9	-1.3	1.5	1.4	1.7	1.6	-0.8	-0.1	1.4	0.6	-1.6	1.3	-0.4	-1.2	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.0	4.7	9.9	2.0	-2.0	-1.9	-2.6	-1.8	-0.7	-2.3	-1.9	-2.0	1.0	-2.1	-2.6	-3.0	-3.1
Illnesses of father: Heart disease	10.1	14.0	19.2	-4.1	4.3	4.3	3.8	4.2	1.0	2.8	4.4	3.8	-4.2	4.1	3.7	2.4	3.5
Illnesses of siblings: Diabetes	0.1	0.2	1.5	-0.2	0.1	0.1	-0.1	0.1	-1.2	0.4	0.1	0.1	-0.8	-0.2	-0.0	-0.1	0.0
Smoking status: Previous	0.2	0.3	1.4	0.1	-0.4	-0.4	0.7	0.1	0.2	-0.6	-0.4	0.0	0.7	-0.2	-1.2	-0.6	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.5	7.1	-2.2	2.3	2.3	1.8	2.0	2.7	1.5	2.2	1.8	-1.9	1.6	1.2	0.4	1.3
Whole body fat-free mass	0.4	2.1	4.7	-1.8	1.7	1.7	0.9	1.7	1.4	1.3	1.7	1.5	-2.2	1.1	0.9	-0.3	0.8
Leg fat-free mass (right)	0.2	0.8	2.6	-1.1	1.0	1.1	0.4	1.0	0.5	0.9	1.1	0.9	-1.6	0.6	0.6	-0.3	0.5
Arm fat percentage (left)	3.8	15.2	23.2	3.8	-3.8	-3.8	-4.5	-3.4	-4.8	-4.3	-3.7	-4.4	1.7	-4.0	-3.7	-3.6	-4.3
Average weekly red wine intake	2.0	3.0	5.2	-2.3	2.1	2.1	2.2	2.0	1.7	1.8	2.1	0.4	-2.1	1.5	0.1	-0.1	1.5
Handedness (chirality/laterality): Left-handed	0.6	0.8	1.5	-0.9	1.0	1.0	1.0	1.2	0.5	0.7	0.9	1.1	-1.1	0.8	0.4	-0.1	0.6
Mood swings	3.7	6.6	8.9	2.9	-2.9	-3.0	-2.2	-2.4	-2.3	-1.8	-3.0	-2.5	2.7	-2.6	-2.8	-2.0	-2.4
Loneliness, isolation	7.0	9.6	13.1	3.6	-3.6	-3.6	-3.4	-3.1	-1.7	-2.3	-3.6	-3.5	3.0	-3.2	-2.9	-2.3	-3.1
Long-standing illness, disability or infirmity	3.6	5.6	10.7	2.4	-2.4	-2.5	-2.9	-1.9	-2.3	-1.6	-2.4	-3.3	1.0	-2.7	-2.5	-1.9	-2.4
Ever had bowel cancer screening	0.8	0.9	3.5	1.1	-0.9	-0.9	-0.6	-1.3	0.8	-0.3	-0.9	-0.3	1.9	-0.4	0.3	1.4	-0.7
Diabetes diagnosed by doctor	1.1	1.9	3.6	1.7	-1.7	-1.6	-1.1	-1.6	-1.9	-0.9	-1.6	0.1	1.7	-1.4	-0.3	1.3	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	3.0	0.2	-0.4	-0.4	-1.0	-0.3	0.9	-1.1	-0.4	-1.4	-0.6	-0.9	-1.4	-1.7	-1.0
Friendships satisfaction	0.4	0.5	2.4	0.2	-0.3	-0.4	0.8	-0.3	0.9	0.6	-0.3	0.7	1.6	0.2	0.4	1.0	1.0
Qualifications: nursing, teaching	0.3	0.5	1.5	-0.8	0.9	0.9	0.7	0.3	-0.6	-0.0	0.8	1.2	-0.7	0.8	0.6	0.5	0.4
Commuting to job workplace: Walk	1.1	1.2	1.8	1.3	-1.3	-1.3	-1.0	-1.0	-0.8	-1.0	-1.4	-1.2	1.2	-1.1	-1.1	-0.4	-0.6
Eye problems/disorders: Cataract	1.2	1.4	8.6	-0.1	-0.3	-0.2	-0.4	-0.1	-0.6	-0.4	-0.2	-0.8	-1.1	-0.8	-2.2	-2.9	-1.7
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	3.5	1.7	-1.7	-1.6	-1.6	-1.6	-0.8	-0.9	-1.7	-0.7	1.9	-1.4	-1.0	-0.5	-1.9
Medication for cholesterol	2.0	3.0	6.7	-1.6	1.5	1.6	1.3	1.3	2.6	1.7	1.5	2.1	-0.7	1.6	2.3	2.0	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	3.2	1.5	-1.5	-1.5	-1.1	-1.6	0.8	-0.9	-1.5	-1.1	1.8	-1.2	-0.9	-0.2	-0.8
Back pain experienced in last month	1.4	2.0	3.7	1.6	-1.7	-1.6	-1.9	-1.4	0.4	-0.9	-1.6	-1.2	1.8	-1.7	-0.7	-0.4	-1.3
Mineral and other dietary supplements	2.3	3.1	6.7	-1.4	1.7	1.6	2.3	1.7	0.3	1.7	1.7	2.6	-0.9	2.2	1.9	1.6	2.0
Breast cancer (self-reported)	0.7	0.9	2.4	-1.2	1.0	1.0	1.1	1.1	-0.1	1.6	1.0	0.8	-0.9	0.8	0.2	0.1	0.9
Asthma (self-reported)	5.8	11.6	16.3	4.0	-3.9	-4.0	-3.9	-3.4	-1.9	-2.7	-3.9	-4.0	3.5	-4.0	-2.8	-1.2	-3.1
Osteoporosis (self-reported)	2.9	3.6	6.5	1.5	-1.6	-1.6	-2.5	-1.4	-1.2	-1.7	-1.7	-2.2	0.2	-2.3	-2.3	-2.5	-2.2
Osteoarthritis (self-reported)	6.7	8.7	13.9	2.9	-3.0	-3.0	-3.5	-2.4	-3.3	-2.2	-3.0	-3.7	1.3	-3.2	-2.8	-2.8	-3.3
Medication: Aspirin	1.2	1.6	2.4	-1.5	1.5	1.5	1.5	1.4	0.8	1.2	1.5	1.0	-1.5	1.3	0.4	0.6	1.4
Medication: Gliclazide	0.9	1.0	2.6	1.2	-1.2	-1.1	-1.0	-1.6	-0.6	-0.5	-1.2	-0.2	1.3	-1.0	-0.1	0.9	-0.4
Illnesses of father: None of the above (group 1)	0.1	0.1	0.2	-0.4	0.2	0.2	0.4	0.2	0.3	0.4	0.1	0.1	0.0	0.1	-0.1	0.1	0.4
Smoking status: Current	10.9	17.3	24.5	4.6	-4.5	-4.6	-4.3	-4.2	-2.1	-3.0	-4.5	-4.7	3.4	-4.9	-4.9	-3.7	-3.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.4	0.3	-0.4	-0.4	-0.6	-0.5	0.2	-0.1	-0.4	-0.1	0.6	-0.6	-0.4	-0.2	-0.3
Whole body water mass	0.4	2.3	4.8	-1.9	1.8	1.8	1.0	1.8	1.4	1.5	1.8	1.6	-2.2	1.2	1.0	-0.2	0.9
Leg predicted mass (right)	0.2	0.8	2.6	-1.1	1.1	1.1	0.4	1.0	0.5	1.0	1.1	1.0	-1.6	0.7	0.7	-0.2	0.5
Arm fat mass (left)	1.7	6.9	10.6	2.4	-2.4	-2.4	-3.2	-2.1	-3.2	-2.8	-2.4	-2.9	0.6	-2.8	-2.6	-2.9	-3.0
Number of self-reported non-cancer illnesses	6.8	11.9	16.2	3.4	-3.4	-3.4	-4.0	-3.2	-3.4	-3.3	-3.4	-3.9	1.9	-3.7	-3.5	-3.1	-4.0
Average weekly champagne plus white wine intake	0.4	0.5	1.2	0.5	-0.4	-0.4	-0.9	-0.6	-0.9	-0.4	-0.4	-0.9	-0.1	-1.0	-0.9	-0.9	-1.1
Miserableness	8.6	15.0	24.1	4.8	-4.6	-4.7	-3.4	-3.9	-3.1	-3.1	-4.7	-3.2	4.9	-4.1	-3.5	-1.6	-3.0
Guilty feelings	10.1	15.2	19.4	4.2	-4.4	-4.4	-4.1	-3.8	-2.8	-2.8	-4.3	-4.0	3.0	-4.1	-4.2	-3.9	-4.0
Wears glasses or contact lenses	0.4	0.5	1.1	0.9	-0.8	-0.8	-1.1	-0.9	0.2	-0.8	-0.7	-0.7	0.5	-1.0	0.1	0.4	-0.2
Ever taken oral contraceptive pill	0.5	0.6	2.0	-0.9	0.7	0.7	0.4	0.5	1.3	1.4	0.7	0.3	-0.9	0.4	-0.4	-0.8	0.2
Hearing aid user	0.1	0.2	0.8	-0.2	0.0	0.0	0.5	0.2	-0.6	-0.1	0.0	-0.2	-0.2	-0.1	-0.9	-0.8	-0.1
Mother’s age at death	0.1	0.2	0.6	0.3	-0.1	-0.2	0.2	-0.4	0.5	0.6	-0.2	0.0	0.7	-0.0	0.3	0.8	-0.0
Financial situation satisfaction	0.6	0.7	4.0	0.6	-0.7	-0.7	-0.6	-0.8	-2.0	-0.5	-0.7	-0.6	0.3	-0.4	-0.8	-1.2	-0.7
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.3	-0.7	0.7	0.6	0.9	0.8	-0.5	0.8	0.7	-0.4	-1.1	0.5	-0.8	-1.1	0.2
Commuting to job workplace: Public transport	1.1	1.3	2.6	0.6	-0.9	-0.9	-1.2	-0.9	-0.6	-0.8	-0.9	-1.5	0.0	-1.5	-1.6	-1.2	-1.6
Eye problems/disorders: Glaucoma	1.1	1.4	5.7	-1.2	1.3	1.3	0.8	1.1	2.4	0.9	1.3	0.3	-1.5	1.1	0.4	-0.5	0.7
Medication: Blood pressure	0.7	1.3	3.0	-1.0	1.4	1.2	1.7	1.2	-0.1	1.2	1.4	1.0	-1.0	1.5	0.6	0.3	1.0
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.8	-0.1	0.4	0.4	0.1	0.4	0.9	0.6	0.4	0.2	0.3	0.7	1.5	1.7	0.7
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.9	-0.0	-0.2	-0.1	-0.4	-0.4	0.9	0.4	-0.1	-0.7	0.1	-0.5	-0.4	0.0	-0.1
High cholesterol (Self-reported)	10.7	18.9	39.4	3.8	-3.8	-3.8	-4.0	-3.6	-6.3	-5.2	-3.8	-4.8	1.5	-3.7	-5.0	-4.8	-4.9
Medication: Bendroflumethiazide	0.4	0.7	1.3	-0.8	1.1	1.0	1.0	0.8	-0.3	0.1	1.1	0.9	-1.1	1.1	0.5	-0.0	0.3
Medication: Paracetamol	3.1	4.8	9.1	1.9	-2.1	-2.1	-2.4	-1.7	-3.0	-1.9	-2.1	-2.2	0.3	-2.5	-2.7	-2.4	-2.2
Medication: Lisinopril	3.5	4.5	7.7	-2.0	2.2	2.2	2.8	2.3	1.4	1.7	2.2	2.3	-1.3	2.4	1.9	2.1	2.4
Medication: Atorvastatin	3.7	4.5	5.9	2.4	-2.2	-2.2	-2.1	-2.0	-2.4	-2.3	-2.2	-2.4	1.4	-1.9	-2.0	-1.8	-2.3
Illnesses of father: High blood pressure	4.1	5.0	6.9	2.6	-2.5	-2.5	-2.1	-2.6	-1.8	-2.1	-2.5	-1.9	2.2	-2.2	-2.3	-1.6	-2.2
Alcohol drinker status: Never	0.1	0.1	0.5	-0.0	0.2	0.2	-0.7	0.4	-0.7	0.0	0.2	0.0	-0.7	-0.1	0.2	-0.2	-0.2
Ever smoked	4.6	8.0	15.8	2.9	-3.1	-3.2	-1.8	-2.4	-1.2	-2.6	-3.2	-2.8	3.1	-3.1	-4.0	-2.8	-2.7
Basal metabolic rate	0.2	1.1	3.7	-1.4	1.2	1.3	0.4	1.3	0.9	0.9	1.2	1.0	-1.9	0.7	0.6	-0.6	0.4
Leg fat percentage (left)	4.8	17.4	26.1	3.9	-3.9	-3.9	-5.0	-3.5	-4.2	-4.5	-3.9	-5.1	1.4	-4.5	-4.2	-4.4	-4.7
Arm fat-free mass (left)	0.4	1.9	4.5	-1.7	1.6	1.7	0.9	1.7	1.5	1.2	1.6	1.2	-2.1	1.0	0.7	-0.6	0.7
Number of operations (self-reported)	0.1	0.2	0.4	-0.3	0.5	0.5	-0.0	0.6	-0.6	-0.1	0.4	-0.2	-0.6	0.4	0.1	-0.2	-0.4
Average weekly beer plus cider intake	0.9	1.3	8.3	0.2	-0.5	-0.5	-0.7	0.2	-0.9	-1.3	-0.5	-1.0	-0.7	-0.6	-1.5	-2.9	-1.3
Irritability	2.3	4.0	9.5	2.7	-2.5	-2.5	-1.6	-1.9	-0.8	-1.1	-2.4	-2.0	3.1	-1.5	-1.4	-0.8	-1.8
Risk taking	4.5	6.6	10.1	2.9	-2.8	-2.9	-2.4	-2.5	-0.7	-1.5	-2.8	-2.9	2.6	-3.1	-3.2	-2.1	-2.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.5	0.6	-0.6	-0.6	-0.4	-0.6	-0.1	-0.4	-0.6	-0.1	0.7	-0.4	-0.1	0.1	-0.4
Fractured/broken bones in last 5 years	2.5	3.2	9.7	1.1	-1.2	-1.2	-2.1	-0.9	0.0	-1.9	-1.2	-2.7	-0.3	-1.8	-2.1	-3.1	-2.3
Age started oral contraceptive pill	3.3	4.1	5.3	-2.3	2.3	2.3	2.0	2.2	1.5	1.9	2.3	1.6	-2.2	2.0	1.9	1.6	2.1
Diastolic blood pressure, automated reading	4.2	13.0	19.5	4.1	-4.2	-4.3	-3.0	-4.0	-2.4	-3.7	-4.2	-3.1	4.4	-4.1	-3.4	-1.5	-2.7
Ever depressed for a whole week	4.0	5.0	7.3	2.7	-2.7	-2.7	-2.5	-2.7	-1.1	-1.1	-2.7	-1.5	2.7	-2.7	-2.0	-1.2	-1.7
Unable to work because of sickness or disability	0.6	0.7	2.5	-0.6	0.9	0.8	0.6	0.9	0.0	1.6	0.9	0.8	-0.6	0.8	0.9	0.7	1.1
Commuting to job workplace: Cycle	1.3	1.6	2.4	1.2	-1.4	-1.3	-1.2	-1.2	1.1	-0.8	-1.4	-1.4	1.5	-1.4	-1.3	-0.9	-1.3
Myopia	0.6	0.8	2.8	-0.2	0.3	0.3	0.5	0.1	1.0	1.4	0.3	1.1	0.7	0.8	1.4	1.7	1.0
Vascular/heart problems diagnosed by doctor	0.9	2.4	5.5	1.9	-1.9	-1.9	-2.0	-2.0	0.2	-0.2	-1.9	-0.8	2.3	-1.5	0.3	1.4	-0.6
Cholesterol lowering medication	9.2	13.6	18.3	3.6	-3.5	-3.5	-3.8	-3.4	-3.9	-4.1	-3.5	-4.3	1.8	-3.7	-4.1	-3.7	-4.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.5	0.2	-0.2	-0.2	-0.5	-0.0	-0.9	-1.6	-0.2	-1.0	-0.0	-0.0	-0.7	-1.2	-1.4
Pain experienced in last month	4.3	7.1	12.1	-3.2	3.2	3.2	3.0	3.0	-0.0	2.4	3.2	2.5	-3.5	2.9	1.8	0.6	2.3
Supplements: Calcium	4.1	4.6	10.6	1.3	-1.6	-1.6	-2.5	-1.6	-1.3	-1.4	-1.6	-3.3	0.0	-2.4	-2.6	-3.1	-3.0
Basal cell carcinoma (self-reported)	0.3	0.4	2.3	0.3	-0.2	-0.1	-0.1	-0.7	1.5	-1.1	-0.1	-0.1	1.0	-0.0	0.4	0.6	-0.4
Heart attack/myocardial infarction (self-reported)	12.2	15.7	23.0	-4.5	4.5	4.5	4.3	4.8	2.1	4.5	4.5	3.5	-4.7	4.2	2.6	0.6	3.5
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.8	-1.1	0.8	0.8	1.2	0.5	1.3	1.7	0.9	1.1	-0.3	0.9	0.8	0.8	1.1
Heart disease (siblings)	2.4	2.9	7.5	-1.4	1.4	1.4	1.3	1.4	-0.3	1.5	1.5	1.6	-1.5	1.8	2.7	2.5	2.1
Alcohol drinker status: Previous	2.6	2.9	5.5	2.1	-1.9	-2.0	-1.6	-1.6	-0.9	-1.6	-1.9	-1.3	2.4	-1.8	-1.3	-1.0	-1.6
Pack years of smoking	3.7	5.5	7.8	2.7	-2.7	-2.7	-2.8	-2.6	-1.8	-2.3	-2.7	-2.3	2.1	-2.8	-1.8	-1.0	-1.6
Impedance of whole body	0.2	0.8	3.2	0.8	-0.8	-0.8	-0.1	-0.7	1.5	-0.4	-0.8	-1.2	1.8	-0.5	-0.7	0.2	-0.0
Leg fat mass (left)	2.2	8.6	13.6	2.6	-2.6	-2.6	-3.7	-2.3	-3.0	-3.2	-2.6	-3.5	0.5	-3.2	-3.0	-3.5	-3.4
Arm predicted mass (left)	0.2	1.3	3.3	-1.4	1.3	1.4	0.5	1.3	1.2	0.9	1.3	1.1	-1.8	0.7	0.7	-0.4	0.6