Best TWAS P=3.11e-10 · Best GWAS P=8.3e-23 conditioned to 3.95e-16
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ABCA12 | 0.06 | 0.01 | bslmm | 579 | 0.01 | 0.0127 | -4.9 | -6.3 | 3.1e-10 | -0.35 | 0.11 | 0.06 | TRUE |
2 | GTEx | Brain Hippocampus | ATIC | 0.53 | 0.00 | enet | 22 | 0.14 | 0.0003 | -2.5 | 5.4 | 6.4e-08 | 0.40 | 0.06 | 0.21 | FALSE |