Best TWAS P=1.07e-08 · Best GWAS P=7.51e-14 conditioned to 7.54e-13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | CLIC4 | 0.05 | 0.03 | lasso | 3 | 0.04 | 3.9e-06 | 3.7 | 5.7 | 1.1e-08 | -0.05 | 0.95 | 0.03 | FALSE |
| 2 | NTR | Blood | CLIC4 | 0.03 | 0.02 | lasso | 6 | 0.02 | 1.4e-06 | 5.9 | 5.7 | 1.4e-08 | -0.08 | 0.96 | 0.04 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | CLIC4 | 0.04 | 0.04 | blup | 65 | 0.02 | 1.7e-02 | 5.6 | -5.7 | 1.1e-08 | 0.06 | 0.02 | 0.59 | TRUE |