[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr1:26,327,671-30,246,262

Best TWAS P=1.25e-13 · Best GWAS P=1.75e-09 conditioned to 0.475

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PIGV	0.04	0.03	bslmm	295	0.03	4.2e-05	6.0	-5.7	1.3e-08	-0.97	0.03	0.97	FALSE
2	GTEx	Adipose Subcutaneous	PIGV	0.04	0.04	lasso	6	0.03	2.6e-03	5.8	-6.0	1.5e-09	-0.98	0.03	0.95	FALSE
3	GTEx	Artery Aorta	PIGV	0.11	0.10	lasso	9	0.08	2.7e-05	5.9	-6.8	8.9e-12	-0.94	0.03	0.96	FALSE
4	GTEx	Artery Aorta	PHACTR4	0.26	0.27	lasso	8	0.21	8.7e-12	-4.9	5.3	1.1e-07	-0.02	0.05	0.95	TRUE
5	GTEx	Breast Mammary Tissue	PIGV	0.10	0.14	lasso	10	0.10	7.6e-06	5.8	-5.9	3.8e-09	-0.97	0.03	0.97	FALSE
6	GTEx	Breast Mammary Tissue (Female)	PIGV	0.10	0.08	lasso	3	0.06	6.0e-03	5.9	-5.9	3.8e-09	-0.97	0.03	0.90	FALSE
7	GTEx	Colon Transverse	PIGV	0.17	0.15	lasso	2	0.14	3.4e-07	5.9	-5.9	3.8e-09	-0.97	0.03	0.97	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	PIGV	0.13	0.02	lasso	10	0.01	1.2e-01	5.9	-6.1	1.2e-09	-0.93	0.03	0.84	FALSE
9	GTEx	Esophagus Mucosa	PIGV	0.16	0.15	lasso	6	0.14	7.0e-10	5.7	-5.9	4.1e-09	-0.98	0.04	0.96	FALSE
10	GTEx	Esophagus Muscularis	PIGV	0.09	0.07	enet	25	0.13	3.4e-08	6.0	-7.4	1.2e-13	-0.88	0.03	0.97	TRUE
11	GTEx	Pituitary	PIGV	0.25	0.12	lasso	10	0.02	8.8e-02	5.9	-6.4	1.4e-10	-0.97	0.03	0.83	FALSE
12	GTEx	Prostate	RP1-50O24.6	0.15	0.02	lasso	9	0.02	1.1e-01	5.9	5.9	3.7e-09	0.98	0.03	0.60	FALSE
13	GTEx	Skin Sun Exposed Lower leg	PIGV	0.05	0.07	lasso	2	0.06	5.0e-06	5.8	-5.8	7.6e-09	-0.98	0.03	0.97	FALSE
14	GTEx	Spleen	PIGV	0.16	0.13	lasso	13	0.16	6.6e-05	4.4	-6.3	2.7e-10	-0.70	0.04	0.89	FALSE
15	GTEx	Stomach	PIGV	0.09	0.14	lasso	1	0.12	1.5e-06	5.9	-5.9	3.9e-09	-0.97	0.03	0.97	FALSE
16	GTEx	Testis	SLC9A1	0.14	0.09	enet	5	0.10	5.3e-05	5.2	-5.4	6.4e-08	-0.11	0.19	0.30	FALSE
17	GTEx	Thyroid	PIGV	0.14	0.12	lasso	7	0.10	2.7e-08	5.9	-6.1	8.4e-10	-0.93	0.03	0.97	FALSE
18	GTEx	Thyroid	SLC9A1	0.10	0.05	lasso	2	0.05	2.2e-04	5.2	-5.2	2.0e-07	-0.10	0.28	0.39	FALSE
19	GTEx	Thyroid	MECR	0.10	0.10	lasso	2	0.07	5.0e-06	5.3	-5.3	1.1e-07	0.02	0.01	0.99	TRUE
20	GTEx	Thyroid	ZDHHC18	0.11	0.10	lasso	4	0.13	4.2e-10	4.7	5.5	3.3e-08	0.84	0.14	0.86	FALSE
21	GTEx	Whole Blood	ZDHHC18	0.04	0.02	lasso	1	0.01	5.7e-02	6.0	6.0	1.7e-09	1.00	0.03	0.94	FALSE
22	METSIM	Adipose	PIGV	0.03	0.02	enet	25	0.04	2.8e-06	-1.2	-5.9	3.9e-09	-0.62	0.04	0.93	FALSE
23	METSIM	Adipose	ZDHHC18	0.04	0.03	lasso	2	0.04	3.8e-06	5.9	6.6	3.8e-11	0.82	0.04	0.96	FALSE
24	NTR	Blood	ARID1A	0.03	0.03	enet	20	0.03	7.8e-11	5.8	-6.8	1.5e-11	-0.95	0.04	0.96	FALSE
25	ROSMAP	Brain Pre-frontal Cortex	CD164L2	0.16	0.13	bslmm	220	0.16	2.4e-20	-4.8	-5.9	4.4e-09	-0.03	0.78	0.21	FALSE
26	YFS	Blood	ZDHHC18	0.08	0.11	bslmm	286	0.11	2.1e-33	4.7	5.3	1.0e-07	0.81	0.90	0.10	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	PIGV	0.02	0.02	lasso	10	0.03	1.3e-06	4.7	-5.7	1.4e-08	-0.90	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Colon Adenocarcinoma	PIGV	0.05	0.03	blup	19	0.02	2.0e-02	4.6	-6.0	1.5e-09	-0.89	0.01	0.56	FALSE
29	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CD164L2	0.04	0.06	blup	36	0.06	9.2e-08	-4.9	-5.5	3.3e-08	0.01	0.02	0.98	FALSE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GPN2	0.03	0.01	lasso	9	0.02	3.2e-03	5.9	5.8	8.3e-09	0.97	0.01	0.96	FALSE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PIGV	0.03	0.05	lasso	7	0.04	4.2e-05	5.8	-5.9	3.2e-09	-0.97	0.01	0.99	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	FAM46B	0.04	0.00	blup	23	0.01	3.5e-02	-2.2	-5.5	3.2e-08	-0.57	0.00	0.25	FALSE
33	The Cancer Genome Atlas	Prostate Adenocarcinoma	WASF2	0.03	0.04	lasso	3	0.03	3.2e-04	-5.4	-5.6	1.9e-08	0.04	0.02	0.96	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	FCN3	0.03	0.03	blup	35	0.02	8.0e-03	-4.8	6.0	2.6e-09	0.00	0.01	0.75	TRUE
35	The Cancer Genome Atlas	Thyroid Carcinoma	MECR	0.32	0.09	enet	12	0.16	3.8e-15	5.3	-5.1	2.9e-07	0.02	0.00	0.99	FALSE