Best TWAS P=5.56e-12 · Best GWAS P=6.37e-13 conditioned to 0.00613
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | SENP2 | 0.21 | 0.18 | enet | 33 | 0.19 | 4.2e-22 | 6.7 | -6.5 | 6.8e-11 | -0.86 | 0.07 | 0.93 | FALSE |
2 | METSIM | Adipose | SENP2 | 0.06 | 0.04 | lasso | 5 | 0.03 | 6.2e-06 | 6.8 | 6.9 | 5.6e-12 | 0.81 | 0.02 | 0.98 | TRUE |
3 | YFS | Blood | SENP2 | 0.11 | 0.14 | enet | 42 | 0.15 | 9.8e-47 | 6.6 | 5.5 | 4.3e-08 | 0.83 | 0.09 | 0.91 | FALSE |