[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr3:195,279,119-197,080,597

Best TWAS P=2.61e-10 · Best GWAS P=3.87e-11 conditioned to 0.191

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum PCYT1A 0.12 0.03 enet 21 0.03 1.7e-02 -3.2 5.3 1.2e-07 -0.55 0.08 0.67 FALSE
2 GTEx Artery Tibial RNF168 0.11 0.05 lasso 3 0.06 3.0e-05 -6.2 -6.3 3.0e-10 0.80 0.05 0.95 FALSE
3 GTEx Brain Cerebellum RNF168 0.27 0.08 lasso 6 0.07 3.9e-03 -5.8 -6.1 1.0e-09 0.77 0.05 0.19 FALSE
4 GTEx Breast Mammary Tissue TCTEX1D2 0.07 0.02 enet 17 0.03 6.7e-03 -6.5 -6.0 2.0e-09 0.78 0.04 0.85 FALSE
5 GTEx Breast Mammary Tissue (Male) TCTEX1D2 0.07 0.01 lasso 1 0.03 6.3e-02 -5.4 -5.4 5.6e-08 0.60 0.03 0.21 FALSE
6 GTEx Breast Mammary Tissue (Female) PCYT1A 0.05 0.01 lasso 1 0.00 4.6e-01 5.2 5.2 2.1e-07 -0.43 0.04 0.08 FALSE
7 GTEx Breast Mammary Tissue (Female) UBXN7 0.11 0.03 lasso 3 0.05 1.3e-02 -6.4 5.4 6.1e-08 -0.80 0.03 0.50 FALSE
8 GTEx Cells EBV-transformed lymphocytes UBXN7 0.21 0.12 lasso 5 0.12 1.1e-04 -5.8 -5.4 5.6e-08 0.73 0.15 0.41 FALSE
9 GTEx Cells Transformed fibroblasts RNF168 0.11 0.02 lasso 5 0.03 4.5e-03 -5.8 -5.4 7.8e-08 0.63 0.08 0.33 FALSE
10 GTEx Colon Sigmoid RNF168 0.18 0.05 lasso 3 0.02 4.5e-02 -5.8 -5.7 1.3e-08 0.75 0.06 0.47 FALSE
11 GTEx Esophagus Mucosa UBXN7 0.17 0.02 lasso 4 0.01 5.1e-02 2.4 5.4 8.4e-08 -0.60 0.04 0.32 FALSE
12 GTEx Esophagus Muscularis RNF168 0.11 0.00 lasso 8 0.01 1.3e-01 -6.3 -6.3 2.6e-10 0.63 0.03 0.80 TRUE
13 METSIM Adipose NRROS 0.10 0.01 enet 59 0.04 2.4e-06 -2.0 -5.3 1.3e-07 0.33 0.26 0.25 TRUE
14 The Cancer Genome Atlas Brain Lower Grade Glioma UBXN7 0.02 0.01 blup 45 0.02 4.2e-03 -4.4 6.3 2.7e-10 -0.74 0.03 0.49 FALSE