[Hub]/) : Traits : Systolic Blood Pressure :

chr4:47,645,550-53,598,975

Best TWAS P=1.95e-11 · Best GWAS P=9.71e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland OCIAD1 0.10 -0.01 enet 11 0.02 5.5e-02 -5.4 -6.2 4.4e-10 -0.81 0.06 0.60 FALSE
2 GTEx Artery Aorta OCIAD1 0.09 0.10 lasso 4 0.10 2.4e-06 6.2 -6.2 6.3e-10 -0.95 0.04 0.96 FALSE
3 GTEx Artery Tibial OCIAD1 0.09 0.12 enet 6 0.11 1.1e-08 6.4 -6.2 5.5e-10 -0.95 0.06 0.94 FALSE
4 GTEx Brain Cerebellum OCIAD1 0.10 0.04 lasso 5 0.02 1.1e-01 6.3 -5.9 3.6e-09 -0.89 0.05 0.55 FALSE
5 GTEx Breast Mammary Tissue DCUN1D4 0.08 0.02 enet 11 0.04 2.4e-03 4.8 5.3 9.6e-08 0.41 0.07 0.82 FALSE
6 GTEx Colon Sigmoid OCIAD1 0.08 0.04 lasso 8 0.02 8.6e-02 6.0 -6.5 9.1e-11 -0.89 0.04 0.81 FALSE
7 GTEx Colon Transverse OCIAD1 0.07 0.07 lasso 5 0.05 2.8e-03 6.4 -6.2 5.8e-10 -0.94 0.05 0.91 FALSE
8 GTEx Esophagus Gastroesophageal Junction OCIAD2 0.07 0.01 lasso 4 0.02 8.3e-02 -5.9 -5.5 3.7e-08 -0.74 0.04 0.69 FALSE
9 GTEx Esophagus Mucosa OCIAD1 0.07 0.06 lasso 4 0.06 9.9e-05 5.5 -6.2 5.4e-10 -0.94 0.09 0.90 FALSE
10 GTEx Esophagus Mucosa OCIAD1-AS1 0.11 0.01 lasso 7 0.01 1.2e-01 -4.6 5.3 8.7e-08 0.69 0.05 0.48 FALSE
11 GTEx Esophagus Muscularis OCIAD1 0.12 0.16 lasso 6 0.17 9.1e-11 6.4 -6.2 4.2e-10 -0.93 0.10 0.90 FALSE
12 GTEx Heart Atrial Appendage LRRC66 0.06 0.02 lasso 3 0.01 7.9e-02 5.9 5.9 2.9e-09 0.48 0.04 0.82 FALSE
13 GTEx Nerve Tibial SLAIN2 0.10 0.09 lasso 4 0.08 4.2e-06 -5.7 5.6 1.7e-08 0.53 0.80 0.14 FALSE
14 GTEx Nerve Tibial DCUN1D4 0.10 0.09 lasso 3 0.10 6.8e-08 5.6 5.6 2.4e-08 0.51 0.04 0.96 FALSE
15 GTEx Ovary FRYL 0.12 -0.01 enet 21 0.03 7.2e-02 6.4 6.7 2.5e-11 0.94 0.07 0.49 FALSE
16 GTEx Skin Sun Exposed Lower leg FRYL 0.05 0.01 enet 19 0.02 8.6e-03 -6.1 6.3 3.2e-10 0.68 0.19 0.49 FALSE
17 GTEx Testis DCUN1D4 0.19 0.17 enet 14 0.16 8.7e-08 6.0 5.9 3.5e-09 0.52 0.02 0.98 FALSE
18 GTEx Testis OCIAD2 0.19 0.09 lasso 3 0.10 3.2e-05 -5.0 5.2 1.6e-07 0.50 0.22 0.16 FALSE
19 NTR Blood OCIAD1 0.01 0.01 bslmm 207 0.00 1.8e-02 6.3 -6.7 2.0e-11 -0.95 0.04 0.95 TRUE
20 ROSMAP Brain Pre-frontal Cortex OCIAD1 0.06 0.07 enet 13 0.07 3.8e-09 6.4 -6.4 1.6e-10 -0.89 0.06 0.94 FALSE
21 ROSMAP Brain Pre-frontal Cortex SGCB 0.03 0.03 enet 9 0.03 7.0e-05 5.9 5.1 2.7e-07 0.51 0.05 0.94 FALSE
22 YFS Blood OCIAD2 0.05 0.05 lasso 5 0.04 1.8e-14 -6.1 6.2 7.5e-10 0.60 0.52 0.48 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma OCIAD1 0.05 0.03 enet 8 0.04 1.0e-05 6.4 -6.3 3.1e-10 -0.87 0.01 0.96 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma SLC10A4 0.05 0.07 blup 36 0.07 6.0e-08 6.5 6.7 2.5e-11 0.95 0.01 0.99 FALSE
25 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SLC10A4 0.05 0.02 blup 36 0.03 6.3e-03 -5.3 6.3 3.2e-10 0.86 0.03 0.55 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma FRYL 0.03 0.03 enet 8 0.03 3.2e-04 5.6 6.7 2.9e-11 0.86 0.06 0.76 FALSE
27 The Cancer Genome Atlas Testicular Germ Cell Tumors SLC10A4 0.09 0.04 lasso 4 0.05 7.5e-03 6.4 6.4 1.7e-10 0.90 0.01 0.84 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma FRYL 0.02 0.01 blup 93 0.01 3.6e-02 6.7 6.5 9.6e-11 0.98 0.03 0.76 FALSE