Best TWAS P=4.32e-10 · Best GWAS P=1.9e-10 conditioned to 0.00363
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | TCF7L2 | 0.19 | 0.09 | lasso | 6 | 0.05 | 0.001 | 6.22 | -6.2 | 4.3e-10 | -0.68 | 0.87 | 0.03 | TRUE |
2 | NTR | Blood | VTI1A | 0.02 | 0.00 | blup | 610 | 0.00 | 0.011 | -0.91 | -5.4 | 5.8e-08 | -0.39 | 0.04 | 0.11 | FALSE |