TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Ulcerative Colitis (UC)
:
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chr6:110,883,139-112,621,834
Best TWAS P=7.56e-09 · Best GWAS P=4.55e-11 conditioned to 0.00929
110.8M
111M
111.2M
111.4M
111.6M
111.8M
112M
112.2M
112.4M
112.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
NTR
Blood
KIAA1919
0.02
0.01
blup
390
0.01
1.2e-04
3.3
5.8
7.6e-09
0.59
0.57
0.35
TRUE
3
GTEx
Skin Sun Exposed Lower leg
C6orf3
0.35
0.07
enet
23
0.21
5.6e-17
5.6
-5.2
2.3e-07
-0.73
0.14
0.86
TRUE
5
ROSMAP
Brain Pre-frontal Cortex
TRAF3IP2-AS1
0.24
0.30
bslmm
421
0.30
1.3e-38
5.6
5.4
6.3e-08
0.82
0.40
0.60
FALSE
2
GTEx
Esophagus Mucosa
C6orf3
0.20
0.01
enet
45
0.07
2.8e-05
5.6
-5.3
1.1e-07
-0.50
0.23
0.23
FALSE
1
GTEx
Esophagus Gastroesophageal Junction
C6orf3
0.27
0.01
lasso
6
0.05
8.1e-03
5.6
-5.2
2.5e-07
-0.71
0.02
0.85
FALSE