Best TWAS P=7.56e-09 · Best GWAS P=4.55e-11 conditioned to 0.00929
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | C6orf3 | 0.27 | 0.01 | lasso | 6 | 0.05 | 8.1e-03 | 5.6 | -5.2 | 2.5e-07 | -0.71 | 0.02 | 0.85 | FALSE |
| 2 | GTEx | Esophagus Mucosa | C6orf3 | 0.20 | 0.01 | enet | 45 | 0.07 | 2.8e-05 | 5.6 | -5.3 | 1.1e-07 | -0.50 | 0.23 | 0.23 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | C6orf3 | 0.35 | 0.07 | enet | 23 | 0.21 | 5.6e-17 | 5.6 | -5.2 | 2.3e-07 | -0.73 | 0.14 | 0.86 | TRUE |
| 4 | NTR | Blood | KIAA1919 | 0.02 | 0.01 | blup | 390 | 0.01 | 1.2e-04 | 3.3 | 5.8 | 7.6e-09 | 0.59 | 0.57 | 0.35 | TRUE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | TRAF3IP2-AS1 | 0.24 | 0.30 | bslmm | 421 | 0.30 | 1.3e-38 | 5.6 | 5.4 | 6.3e-08 | 0.82 | 0.40 | 0.60 | FALSE |