[Hub]/) : Traits : Ulcerative Colitis (UC) : ← →

chr7:127,878,155-129,393,341

Best TWAS P=1.84e-10 · Best GWAS P=3.24e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IRF5	0.09	0.04	lasso	4	0.06	2.3e-04	6.3	6.4	1.8e-10	0.97	0.00	1.00	TRUE
6	GTEx	Skin Sun Exposed Lower leg	IRF5	0.10	0.14	lasso	2	0.12	1.9e-10	6.3	6.4	2.1e-10	1.00	0.00	1.00	FALSE
2	GTEx	Colon Transverse	IRF5	0.21	0.22	lasso	4	0.22	8.0e-11	6.3	6.3	3.7e-10	1.00	0.00	1.00	FALSE
5	GTEx	Nerve Tibial	IRF5	0.13	0.09	enet	10	0.07	1.2e-05	6.3	6.2	4.4e-10	0.95	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	IRF5	0.29	0.26	enet	6	0.29	3.1e-17	-5.8	6.2	4.4e-10	0.95	0.00	1.00	FALSE
1	GTEx	Adipose Visceral Omentum	IRF5	0.16	0.08	lasso	4	0.08	8.2e-05	6.3	6.2	4.9e-10	0.99	0.00	1.00	FALSE
3	GTEx	Esophagus Mucosa	IRF5	0.13	0.14	lasso	4	0.13	4.6e-09	6.3	6.2	5.1e-10	1.00	0.00	1.00	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	IRF5	0.10	0.09	lasso	4	0.08	1.6e-16	6.3	6.2	5.5e-10	0.99	0.00	1.00	FALSE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	IRF5	0.23	0.26	lasso	3	0.26	3.6e-27	-5.8	6.2	6.2e-10	0.92	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Rectum Adenocarcinoma	IRF5	0.41	0.13	blup	33	0.23	3.5e-06	-5.8	6.0	2.1e-09	0.89	0.00	0.98	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	IRF5	0.22	0.21	enet	9	0.26	4.6e-25	-5.8	5.9	4.0e-09	0.92	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	IRF5	0.09	0.10	lasso	3	0.08	4.6e-04	-5.8	5.8	7.9e-09	0.85	0.01	0.88	FALSE
4	GTEx	Esophagus Muscularis	IRF5	0.21	0.12	lasso	5	0.11	3.9e-07	6.3	5.7	9.6e-09	0.95	0.00	1.00	FALSE
8	GTEx	Whole Blood	IRF5	0.17	0.06	lasso	4	0.09	1.2e-08	-4.0	5.7	1.3e-08	0.91	0.00	1.00	FALSE
7	GTEx	Thyroid	IRF5	0.14	0.10	enet	6	0.11	1.2e-08	6.3	5.6	2.7e-08	0.85	0.00	1.00	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IRF5	0.11	0.05	blup	30	0.07	2.2e-08	6.3	5.5	4.1e-08	0.85	0.00	1.00	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	IRF5	0.18	0.11	enet	9	0.14	1.6e-15	6.3	5.5	4.4e-08	0.90	0.00	1.00	FALSE
9	METSIM	Adipose	IRF5	0.05	0.04	lasso	7	0.04	2.2e-06	6.3	5.5	4.6e-08	0.95	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IRF5	0.14	0.12	enet	7	0.15	1.8e-16	5.8	5.3	8.6e-08	0.88	0.00	1.00	FALSE
10	YFS	Blood	TNPO3	0.37	0.31	enet	32	0.36	7.4e-125	4.7	-5.3	9.2e-08	-0.72	0.85	0.15	FALSE
17	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IRF5	0.14	0.15	enet	6	0.14	7.0e-10	-5.8	5.3	1.3e-07	0.86	0.01	0.99	FALSE