Best TWAS P=9.3e-12 · Best GWAS P=5.86e-15 conditioned to 5.06e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | TNFSF15 | 0.05 | 0.06 | lasso | 3 | 0.06 | 5.4e-09 | -7.6 | -6.8 | 1.0e-11 | 0.76 | 0.02 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TNFSF15 | 0.02 | 0.01 | blup | 54 | 0.01 | 7.6e-03 | -7.6 | -6.8 | 9.3e-12 | 0.76 | 0.01 | 0.71 | TRUE |