TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
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Ulcerative Colitis (UC)
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chr21:45,398,656-45,902,320
Best TWAS P=3.44e-12 · Best GWAS P=1.77e-13 conditioned to 0.00048
45.4M
45.5M
45.6M
45.7M
45.8M
45.9M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Thyroid Carcinoma
ICOSLG
0.11
0.03
blup
68
0.08
5.6e-08
-4.3
-7.0
3.4e-12
-0.70
0.01
0.98
TRUE
1
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
ICOSLG
0.15
0.02
blup
65
0.04
8.9e-03
-4.0
-5.5
4.4e-08
-0.42
0.03
0.16
FALSE
2
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
ICOSLG
0.14
0.07
blup
68
0.10
8.2e-05
-3.9
-5.2
2.1e-07
-0.47
0.14
0.21
FALSE