Best TWAS P=3.44e-12 · Best GWAS P=1.77e-13 conditioned to 0.00048
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ICOSLG | 0.15 | 0.02 | blup | 65 | 0.04 | 8.9e-03 | -4.0 | -5.5 | 4.4e-08 | -0.42 | 0.03 | 0.16 | FALSE |
| 2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | ICOSLG | 0.14 | 0.07 | blup | 68 | 0.10 | 8.2e-05 | -3.9 | -5.2 | 2.1e-07 | -0.47 | 0.14 | 0.21 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | ICOSLG | 0.11 | 0.03 | blup | 68 | 0.08 | 5.6e-08 | -4.3 | -7.0 | 3.4e-12 | -0.70 | 0.01 | 0.98 | TRUE |