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chr20:61,576,647-62,912,463

Best TWAS P=1.29e-12 · Best GWAS P=3.05e-11 conditioned to 0.578

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ARFRP1	0.07	0.07	lasso	3	0.06	5.3e-08	-5.8	6.1	1.1e-09	-0.55	0.36	0.64	FALSE
2	GTEx	Adrenal Gland	RGS19	0.32	0.20	lasso	8	0.21	5.8e-08	5.1	5.3	1.4e-07	-0.11	0.45	0.05	TRUE
3	GTEx	Artery Tibial	OPRL1	0.10	0.10	lasso	2	0.06	1.1e-05	5.1	5.1	2.8e-07	-0.03	0.87	0.03	FALSE
4	GTEx	Brain Cerebellar Hemisphere	STMN3	0.39	0.08	lasso	5	0.22	2.1e-06	-5.2	-7.1	1.3e-12	0.81	0.01	0.96	TRUE
5	GTEx	Brain Cerebellum	STMN3	0.33	0.12	lasso	10	0.20	1.8e-06	-5.5	-6.0	2.6e-09	0.46	0.33	0.57	FALSE
6	GTEx	Brain Cortex	STMN3	0.25	0.09	lasso	7	0.11	6.8e-04	-5.6	-6.3	2.7e-10	0.46	0.16	0.47	FALSE
7	GTEx	Pancreas	OPRL1	0.39	0.27	lasso	5	0.32	6.9e-14	5.1	5.1	3.0e-07	-0.02	0.97	0.03	FALSE
8	GTEx	Testis	RTEL1	0.19	0.06	lasso	5	0.14	8.0e-07	-5.6	-6.2	4.4e-10	0.42	0.24	0.51	FALSE
9	GTEx	Thyroid	SLC2A4RG	0.12	0.06	lasso	5	0.04	2.4e-04	-5.7	5.5	3.1e-08	-0.40	0.47	0.39	FALSE
10	GTEx	Whole Blood	OPRL1	0.09	0.06	enet	8	0.07	4.3e-07	-5.0	-5.1	2.7e-07	0.03	0.96	0.02	FALSE
11	GTEx	Whole Blood	STMN3	0.10	0.00	lasso	3	0.00	1.2e-01	-6.0	5.6	2.0e-08	-0.48	0.08	0.24	FALSE
12	YFS	Blood	LIME1	0.12	0.19	enet	15	0.19	5.3e-59	-5.7	-5.9	4.0e-09	0.58	0.39	0.61	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	LIME1	0.02	0.03	blup	47	0.02	6.2e-03	-5.6	-5.5	3.4e-08	0.43	0.02	0.77	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZGPAT	0.05	0.04	blup	60	0.05	7.2e-07	-5.5	5.1	3.1e-07	-0.30	0.54	0.41	FALSE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	TNFRSF6B	0.02	0.01	enet	7	0.01	6.9e-03	-5.6	-6.1	1.1e-09	0.53	0.11	0.22	FALSE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RTEL1	0.05	0.04	blup	56	0.03	4.2e-03	-4.0	-6.7	1.9e-11	0.74	0.03	0.39	FALSE
17	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TNFRSF6B	0.05	0.02	blup	44	0.03	2.9e-03	-5.8	-5.6	2.3e-08	0.76	0.02	0.43	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARFRP1	0.03	0.02	lasso	2	0.02	1.2e-03	-5.8	5.8	6.0e-09	-0.57	0.15	0.34	FALSE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZGPAT	0.05	0.06	lasso	3	0.06	5.5e-07	-5.8	6.0	2.3e-09	-0.47	0.48	0.51	FALSE
20	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LIME1	0.10	0.02	blup	47	0.04	1.5e-02	-5.8	-5.2	2.2e-07	0.48	0.01	0.61	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	LIME1	0.05	0.03	blup	47	0.04	3.9e-05	-5.5	-5.9	4.6e-09	0.47	0.03	0.96	FALSE