Best TWAS P=1.86e-19 · Best GWAS P=2.2e-21 conditioned to 1.11e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | ATF6 | 0.23 | 0.08 | lasso | 6 | 0.05 | 3.3e-03 | 9.5 | -6.8 | 1.4e-11 | -0.85 | 0.00 | 0.97 | FALSE |
| 2 | METSIM | Adipose | FCGR2B | 0.07 | 0.03 | lasso | 4 | 0.02 | 1.7e-04 | 5.5 | 5.4 | 8.4e-08 | 0.30 | 0.68 | 0.07 | FALSE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | FCGR2A | 0.17 | 0.08 | enet | 5 | 0.16 | 2.3e-07 | 8.8 | -9.0 | 1.9e-19 | -0.64 | 0.05 | 0.87 | TRUE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | FCGR3A | 0.08 | 0.02 | blup | 18 | 0.03 | 3.0e-02 | 4.9 | -6.9 | 6.3e-12 | -0.42 | 0.01 | 0.23 | FALSE |