TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Ulcerative Colitis (UC)
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chr1:160,851,894-162,630,958
Best TWAS P=1.86e-19 · Best GWAS P=2.2e-21 conditioned to 1.11e-06
160.8M
161M
161.2M
161.4M
161.6M
161.8M
162M
162.2M
162.4M
162.6M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
FCGR2A
0.17
0.08
enet
5
0.16
2.3e-07
8.8
-9.0
1.9e-19
-0.64
0.05
0.87
TRUE
4
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
FCGR3A
0.08
0.02
blup
18
0.03
3.0e-02
4.9
-6.9
6.3e-12
-0.42
0.01
0.23
FALSE
1
GTEx
Testis
ATF6
0.23
0.08
lasso
6
0.05
3.3e-03
9.5
-6.8
1.4e-11
-0.85
0.00
0.97
FALSE
2
METSIM
Adipose
FCGR2B
0.07
0.03
lasso
4
0.02
1.7e-04
5.5
5.4
8.4e-08
0.30
0.68
0.07
FALSE