Best TWAS P=2.3e-12 · Best GWAS P=9.87e-11 conditioned to 0.000301
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | HIP1R | 0.21 | 0.05 | lasso | 5 | 0.07 | 1.5e-05 | 2.1 | 5.1 | 3.1e-07 | -0.24 | 0.61 | 0.05 | FALSE |
| 2 | GTEx | Nerve Tibial | KNTC1 | 0.12 | 0.05 | lasso | 5 | 0.05 | 1.9e-04 | -6.5 | -6.5 | 6.3e-11 | 0.91 | 0.00 | 1.00 | FALSE |
| 3 | METSIM | Adipose | ABCB9 | 0.04 | 0.03 | enet | 19 | 0.03 | 7.7e-05 | -5.3 | -7.0 | 2.3e-12 | 0.47 | 0.20 | 0.18 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | KNTC1 | 0.05 | 0.01 | blup | 64 | 0.02 | 2.4e-03 | -6.4 | -5.5 | 4.8e-08 | 0.94 | 0.00 | 0.89 | FALSE |