TWAS
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Traits
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Pulse rate, automated reading
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chr12:122,318,723-124,162,750
Best TWAS P=2.3e-12 · Best GWAS P=9.87e-11 conditioned to 0.000301
122.5M
123M
123.5M
124M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
METSIM
Adipose
ABCB9
0.04
0.03
enet
19
0.03
7.7e-05
-5.3
-7.0
2.3e-12
0.47
0.20
0.18
TRUE
2
GTEx
Nerve Tibial
KNTC1
0.12
0.05
lasso
5
0.05
1.9e-04
-6.5
-6.5
6.3e-11
0.91
0.00
1.00
FALSE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
KNTC1
0.05
0.01
blup
64
0.02
2.4e-03
-6.4
-5.5
4.8e-08
0.94
0.00
0.89
FALSE
1
GTEx
Esophagus Mucosa
HIP1R
0.21
0.05
lasso
5
0.07
1.5e-05
2.1
5.1
3.1e-07
-0.24
0.61
0.05
FALSE