Best TWAS P=1.64e-18 · Best GWAS P=2.1e-51 conditioned to 1.45e-30
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Ovary | CD46 | 0.21 | 0.08 | enet | 11 | 0.12 | 7.0e-04 | 5.1 | -5.3 | 1.0e-07 | 0.33 | 0.20 | 0.04 | FALSE |
| 2 | GTEx | Thyroid | CD55 | 0.07 | 0.05 | lasso | 4 | 0.07 | 7.2e-06 | -4.3 | 5.6 | 2.0e-08 | -0.15 | 0.93 | 0.00 | TRUE |
| 3 | METSIM | Adipose | CD55 | 0.07 | 0.05 | blup | 366 | 0.06 | 1.7e-09 | 3.6 | 7.0 | 1.9e-12 | -0.22 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CD34 | 0.08 | 0.02 | blup | 80 | 0.02 | 8.2e-04 | 5.3 | -8.8 | 1.6e-18 | 0.52 | 0.03 | 0.22 | TRUE |