TWAS hub - CD46

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.138	0.0290	2.7e-14	0.160	0.129	0.158	0.162	0.150	5.8e-19	2.1e-15	1.0e-18	3.4e-19	7.9e-18
2	GTEx	Adipose Subcutaneous	0.069	0.0260	9.2e-04	0.051	NA	0.024	NA	0.034	4.9e-05	NA	4.3e-03	NA	7.9e-04
3	GTEx	Adipose Visceral Omentum	0.114	0.0490	6.6e-03	0.023	NA	0.013	NA	0.030	2.3e-02	NA	7.0e-02	NA	1.0e-02
4	GTEx	Artery Aorta	0.205	0.0540	2.0e-07	0.183	NA	0.201	NA	0.195	2.3e-10	NA	2.5e-11	NA	5.8e-11
5	GTEx	Artery Tibial	0.266	0.0469	2.8e-16	0.350	NA	0.330	NA	0.343	1.9e-28	NA	1.6e-26	NA	9.0e-28
6	GTEx	Cells EBV-transformed lymphocytes	0.334	0.0840	7.9e-05	0.254	NA	0.147	NA	0.235	7.4e-09	NA	1.6e-05	NA	3.2e-08
7	GTEx	Colon Sigmoid	0.290	0.0800	4.2e-05	0.233	NA	0.112	NA	0.207	9.4e-09	NA	9.5e-05	NA	7.6e-08
8	GTEx	Esophagus Gastroesophageal Junction	0.287	0.0800	9.0e-05	0.235	NA	0.155	NA	0.218	5.4e-09	NA	2.9e-06	NA	2.1e-08
9	GTEx	Esophagus Muscularis	0.375	0.0630	2.6e-14	0.271	NA	0.247	NA	0.284	1.1e-16	NA	3.8e-15	NA	1.5e-17
10	GTEx	Heart Atrial Appendage	0.116	0.0510	9.5e-03	0.098	NA	0.105	NA	0.098	3.8e-05	NA	1.9e-05	NA	3.8e-05
11	GTEx	Nerve Tibial	0.235	0.0497	1.8e-11	0.153	NA	0.192	NA	0.204	5.7e-11	NA	1.4e-13	NA	2.1e-14
12	GTEx	Ovary	0.209	0.0840	9.3e-03	0.078	NA	0.121	NA	0.091	5.8e-03	NA	7.0e-04	NA	3.1e-03
13	TCGA	Brain Lower Grade Glioma	0.100	0.0385	2.3e-11	0.125	0.117	0.122	NA	0.125	4.7e-14	3.2e-13	9.4e-14	NA	5.6e-14
14	TCGA	Thyroid Carcinoma	0.032	0.0230	4.1e-03	0.030	0.025	0.029	NA	0.024	5.8e-04	1.7e-03	6.9e-04	NA	1.8e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Blood White Count	14.3	105.8	125.4	10.8	10.4	11.2	10.5	10.8	11.2	11.0	10.6	11.1	10.9	8.8	8.5	11.0	-5.7
HbA1C	14.2	15.8	24.3	4.1	4.8	4.9	3.3	1.5	4.9	4.6	4.7	3.2	4.0	3.8	3.4	4.9	-0.7
Townsend deprivation index at recruitment	9.2	13.0	15.8	3.7	3.8	3.0	4.0	3.9	3.5	3.8	3.8	3.8	3.8	3.4	3.2	3.9	-2.6
Hearing aid user	7.6	8.6	12.7	2.5	3.2	1.9	3.2	2.7	2.5	2.8	2.9	3.1	2.8	3.5	3.6	2.8	-3.1
Bipolar Disorder or Schizophrenia	6.9	16.9	20.8	4.2	4.5	3.6	4.5	4.2	3.5	4.0	4.2	4.5	4.0	4.6	3.9	4.2	-3.7
Qualifications: nursing, teaching	5.9	9.2	10.7	-3.2	-3.2	-2.8	-3.2	-3.2	-2.9	-3.2	-3.2	-3.3	-3.2	-3.0	-2.5	-3.2	2.1
Maternal smoking around birth	5.8	8.4	10.2	2.9	3.0	3.1	3.1	3.2	2.9	3.1	3.0	3.1	3.0	2.7	2.0	3.1	-1.8
Forced expiratory volume in 1-second (FEV1)	5.8	19.5	26.0	-4.7	-4.5	-3.9	-4.6	-5.0	-5.1	-5.0	-4.6	-4.6	-5.0	-3.6	-3.2	-5.0	1.7
Schizophrenia (2018)	5.6	11.6	14.8	3.5	3.8	2.9	3.6	3.5	3.1	3.4	3.4	3.9	3.4	3.7	3.0	3.5	-2.8
Average weekly champagne plus white wine intake	5.4	7.4	10.2	-2.6	-3.0	-2.5	-2.9	-2.6	-2.5	-2.6	-2.8	-2.7	-2.4	-3.2	-2.8	-2.6	2.7
Mineral and other dietary supplements	5.3	7.1	8.3	2.4	2.8	2.5	2.8	2.5	2.7	2.5	2.5	2.9	2.7	2.8	2.8	2.6	-2.6
Allergy	5.2	11.9	14.6	-3.4	-3.8	-2.5	-3.7	-3.3	-3.4	-3.3	-3.5	-3.7	-3.1	-3.7	-3.6	-3.4	3.6
Relative age of first facial hair	5.1	10.5	12.4	-3.3	-3.4	-3.4	-3.3	-3.3	-3.3	-3.3	-3.4	-3.5	-3.3	-3.2	-2.8	-3.3	2.3
Had major operations	5.0	5.9	8.5	-2.5	-2.5	-2.3	-2.5	-2.7	-2.3	-2.8	-2.4	-2.9	-2.8	-2.1	-1.7	-2.8	0.9
Pain type(s) experienced in last month: Hip pain	4.7	5.9	13.9	1.9	2.6	1.6	2.6	1.8	1.8	1.7	2.0	2.4	1.8	3.3	3.7	1.7	-3.7
Forced expiratory volume in 1-second (FEV1), Best measure	4.6	14.7	19.7	-4.0	-4.0	-2.9	-4.1	-4.3	-4.4	-4.3	-4.0	-4.0	-4.2	-3.4	-2.9	-4.2	2.0
Medication: Ibuprofen	4.6	5.5	7.2	-2.7	-2.3	-2.6	-2.3	-2.6	-2.5	-2.5	-2.4	-2.6	-2.6	-1.8	-1.6	-2.5	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.5	9.6	12.1	-3.3	-3.3	-2.1	-3.5	-3.3	-3.2	-3.2	-3.0	-2.9	-3.2	-3.2	-3.0	-3.2	2.8
Suffer from ‘nerves’	4.4	6.9	8.5	-2.5	-2.7	-2.8	-2.7	-2.7	-2.8	-2.8	-2.6	-2.9	-2.8	-2.4	-2.4	-2.7	1.7
Schizophrenia (2014)	4.1	9.0	12.4	3.1	3.4	2.4	3.2	3.1	2.5	3.1	3.0	3.5	3.0	3.2	2.6	3.1	-2.3
Tinnitus: Yes, now most or all of the time	4.1	4.8	6.4	-2.5	-2.3	-2.4	-2.2	-2.1	-2.1	-2.1	-2.2	-2.2	-2.1	-2.2	-2.3	-2.2	1.8
Supplements: Fish oil (including cod liver oil)	4.1	5.3	7.2	-2.3	-2.3	-2.2	-2.4	-2.4	-2.6	-2.4	-2.2	-2.7	-2.5	-2.1	-2.0	-2.3	1.6
Forced vital capacity (FVC)	4.0	15.5	20.2	-4.1	-4.1	-3.4	-4.1	-4.3	-4.5	-4.4	-4.1	-4.2	-4.4	-3.5	-3.0	-4.3	1.9
Time employed in main current job	3.8	4.4	5.3	-2.1	-2.2	-1.7	-2.3	-2.2	-1.9	-2.1	-2.2	-2.3	-2.2	-2.1	-2.2	-2.2	1.7
Wheeze or whistling in the chest in last year	3.8	6.8	8.8	2.2	2.8	1.9	2.8	2.7	2.7	2.7	2.6	3.0	2.6	2.6	2.8	2.7	-2.1
Financial difficulties in last 2 years	3.6	4.9	7.1	2.0	2.5	1.5	2.5	2.1	2.2	2.1	2.4	1.9	2.1	2.4	2.3	2.1	-2.7
Medication: Atorvastatin	3.6	4.5	7.4	1.8	2.3	2.3	2.2	1.8	1.8	1.7	2.1	1.9	1.7	2.6	2.5	1.8	-2.7
Lung FVC	3.5	18.0	20.5	-4.2	-4.5	-4.0	-4.5	-4.4	-4.5	-4.4	-4.2	-4.4	-4.5	-4.3	-3.8	-4.3	3.3
Medication: Ibuprofen (e.g. Nurofen)	3.5	4.4	5.5	-2.3	-2.1	-2.2	-2.2	-2.1	-2.0	-2.1	-2.1	-2.4	-2.2	-2.0	-1.9	-2.1	1.7
Bipolar Disorder (2018)	3.4	5.4	7.2	2.3	2.5	2.2	2.6	2.3	1.7	2.1	2.4	2.4	2.2	2.7	2.5	2.3	-2.5
Medication: Levothyroxine sodium	3.4	5.7	8.1	-2.7	-2.4	-2.8	-2.4	-2.4	-2.6	-2.5	-2.4	-2.5	-2.5	-2.0	-2.1	-2.6	1.0
Hayfever, allergic rhinitis or eczema	3.3	7.3	9.5	2.8	3.0	1.9	2.9	2.4	2.6	2.5	2.7	2.7	2.2	3.1	3.0	2.5	-3.1
Asthma (self-reported)	3.3	6.6	9.2	2.5	2.8	1.4	2.7	2.7	2.9	2.7	2.7	3.0	2.6	2.5	2.4	2.8	-1.9
Forced vital capacity (FVC), Best measure	3.2	11.6	15.1	-3.4	-3.6	-2.3	-3.6	-3.7	-3.9	-3.7	-3.6	-3.7	-3.7	-3.3	-2.9	-3.6	2.0
Osteoarthritis (self-reported)	3.1	4.0	8.6	-2.4	-1.9	-2.9	-1.9	-2.0	-2.1	-2.0	-1.9	-2.4	-2.0	-1.6	-1.5	-2.0	0.7
Allergy or Eczema	2.9	7.7	9.8	2.8	3.1	2.3	3.0	2.6	2.6	2.6	2.9	2.8	2.4	3.1	3.1	2.7	-3.0
Respiratory disease	2.9	6.4	7.8	2.3	2.8	0.8	2.8	2.6	2.5	2.5	2.7	2.8	2.4	2.8	2.7	2.6	-2.4
Medication: Amlodipine	2.9	4.1	5.7	1.9	2.3	1.7	2.2	1.8	1.8	1.9	1.9	2.0	2.0	2.3	2.4	2.0	-2.0
Supplements: Glucosamine	2.8	3.7	6.7	-1.8	-2.1	-1.6	-2.1	-1.6	-1.8	-1.6	-1.8	-1.7	-1.7	-2.4	-2.1	-1.7	2.6
Asthma	2.8	5.5	8.0	2.3	2.5	1.2	2.5	2.4	2.6	2.5	2.4	2.8	2.3	2.3	2.1	2.5	-1.8
Chronic bronchitis/emphysema (mother)	2.8	3.2	5.4	1.7	1.9	1.0	2.1	1.8	1.6	1.7	1.8	1.5	1.8	2.0	2.3	1.7	-1.9
Average weekly spirits intake	2.7	3.3	4.5	-2.1	-2.0	-1.6	-1.9	-1.7	-1.9	-1.7	-1.9	-1.5	-1.6	-1.9	-1.9	-1.8	1.8
Medication: Lisinopril	2.7	3.5	4.6	-2.1	-2.0	-1.8	-1.9	-2.0	-1.9	-2.1	-2.0	-1.9	-2.1	-1.5	-1.7	-2.1	0.6
Knee pain experienced in last month	2.6	4.0	6.0	-2.1	-1.9	-2.3	-1.9	-2.2	-2.3	-2.4	-2.2	-2.4	-2.1	-1.5	-1.1	-2.3	0.5
Pulse wave reflection index	2.5	3.1	4.0	1.7	1.9	0.8	1.9	1.8	1.8	1.9	1.8	1.9	2.0	1.8	1.7	1.9	-1.0
Depressed Affect (Nagel 2018)	2.4	5.0	6.5	-2.4	-2.2	-2.4	-2.2	-2.4	-2.5	-2.5	-2.5	-2.1	-2.5	-1.8	-1.8	-2.5	0.9
Tinnitus: Yes, but not now, but have in the past	2.4	2.5	6.7	1.5	1.7	1.6	1.5	0.9	0.9	1.0	1.4	1.4	1.0	2.1	2.6	1.1	-2.3
Past tobacco smoking	2.4	4.5	6.6	-2.2	-2.1	-1.7	-2.2	-2.5	-2.6	-2.5	-2.2	-2.4	-2.3	-1.6	-1.2	-2.4	0.8
Had other major operations	2.4	2.9	3.9	-1.5	-1.8	-1.9	-1.8	-1.5	-1.2	-1.6	-1.7	-1.7	-1.8	-1.9	-2.0	-1.6	1.7
Systolic Blood Pressure	2.3	11.3	24.1	2.8	3.8	0.8	3.7	2.5	2.5	2.4	3.2	3.3	2.5	4.6	4.9	2.4	-4.9
LDL Cholesterol	2.2	3.5	5.8	1.5	2.0	1.9	2.0	1.6	1.5	1.6	1.8	1.7	1.6	2.3	2.1	1.8	-2.4
Eye problems/disorders: Diabetes related eye disease	2.2	2.4	4.1	1.4	1.6	1.7	1.5	1.5	1.7	1.6	1.7	2.0	1.4	1.5	1.2	1.6	-0.8
Father’s age at death	2.2	3.0	4.1	-1.7	-1.6	-1.5	-1.8	-1.9	-1.9	-1.9	-1.8	-1.9	-2.0	-1.5	-1.4	-2.0	0.8
Angina (self-reported)	2.2	2.9	5.7	1.5	1.8	1.6	1.8	1.2	1.4	1.2	1.6	1.5	1.3	2.2	2.4	1.2	-2.3
Age at last live birth	2.2	3.2	4.8	-2.0	-1.6	-1.7	-1.8	-2.2	-2.2	-2.1	-1.8	-1.9	-2.0	-1.2	-1.1	-2.1	0.4
Medication: Gliclazide	2.2	2.5	5.9	1.4	1.5	1.4	1.4	1.6	2.4	1.9	1.6	1.9	1.7	1.1	0.5	1.9	0.2
Alzheimer’s Disease (including proxy)	2.1	3.0	9.7	-2.1	-1.4	-3.1	-1.6	-1.8	-1.6	-1.3	-1.3	-1.5	-1.8	-1.4	-1.4	-2.2	0.6
HDL Cholesterol	2.1	3.6	5.1	-1.9	-2.0	-1.9	-2.0	-1.8	-1.8	-1.9	-1.8	-2.3	-1.8	-2.1	-1.8	-1.8	1.7
Emphysema/chronic bronchitis	2.1	2.4	3.4	1.6	1.7	0.6	1.8	1.9	1.6	1.8	1.5	1.8	1.8	1.4	1.3	1.7	-1.1
Number of operations (self-reported)	2.1	3.1	4.2	-1.9	-1.9	-1.3	-1.9	-1.9	-1.5	-1.9	-1.7	-2.0	-1.9	-1.7	-1.6	-1.9	1.2
Basal cell carcinoma (self-reported)	2.1	2.5	4.5	1.5	1.7	2.1	1.6	1.4	1.3	1.4	1.5	1.6	1.4	1.7	1.6	1.6	-1.5
Alzheimer’s Disease (in mother)	2.0	2.3	5.4	-1.5	-1.4	-2.3	-1.4	-1.5	-1.9	-1.6	-1.5	-1.3	-1.7	-1.1	-1.0	-1.7	0.5
Angina	2.0	2.7	5.4	1.4	1.7	1.6	1.7	1.1	1.3	1.1	1.6	1.5	1.2	2.2	2.3	1.2	-2.3
Commuting to job workplace: Walk	2.0	2.2	3.2	1.7	1.5	1.8	1.5	1.4	1.7	1.5	1.5	1.2	1.5	1.3	1.4	1.5	-1.0
Blood Platelet Count	1.9	21.7	27.8	4.8	4.7	4.8	4.8	5.0	5.3	5.0	4.8	5.0	5.0	4.0	3.9	5.1	-2.3
Diabetes (self-reported)	1.9	2.9	6.3	1.7	1.6	2.4	1.6	1.9	2.5	1.9	1.8	1.6	1.7	1.1	0.7	1.8	-0.5
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	15.7	0.7	1.6	-0.3	1.6	0.5	0.7	0.3	1.1	1.2	0.4	2.8	3.1	0.4	-4.0
Depression (self-reported)	1.9	2.3	4.6	1.3	1.8	0.9	1.7	1.3	1.1	1.3	1.8	1.6	1.3	1.9	1.1	1.5	-2.1
Medication for pain relief, constipation, heartburn	1.9	3.2	4.8	1.9	1.9	1.6	1.9	1.7	1.4	1.6	1.7	1.6	1.9	1.9	2.2	1.6	-1.9
Mean time to correctly identify matches	1.9	3.7	9.4	2.1	0.8	1.5	0.8	2.3	2.4	2.4	1.3	1.6	2.1	-0.8	-1.8	2.3	3.1
Age started oral contraceptive pill	1.9	2.3	3.8	-1.3	-1.7	-1.4	-1.6	-1.4	-1.4	-1.4	-1.4	-1.6	-1.2	-1.7	-1.7	-1.4	1.9
Relative age voice broke	1.8	2.7	4.4	-1.4	-1.6	-1.8	-1.6	-1.7	-1.8	-1.8	-1.7	-2.1	-1.9	-1.5	-1.2	-1.7	0.9
High blood pressure (mother)	1.8	2.6	3.2	-1.7	-1.7	-1.4	-1.8	-1.8	-1.5	-1.7	-1.7	-1.4	-1.7	-1.4	-1.7	-1.7	1.1
Mood swings	1.8	3.3	4.2	-1.9	-1.8	-2.0	-1.8	-1.8	-2.0	-1.8	-2.1	-1.7	-1.8	-1.6	-1.7	-2.0	1.2
Pain experienced in last month	1.8	3.0	5.4	1.8	1.5	2.3	1.5	2.0	2.0	2.1	1.7	2.1	2.2	0.8	0.4	2.0	0.4
Medication: Metformin	1.7	2.4	4.5	1.4	1.6	1.8	1.6	1.5	2.1	1.6	1.7	1.5	1.4	1.4	1.1	1.6	-1.2
Mouth/teeth dental problems: Dentures	1.7	2.8	4.8	1.6	1.9	1.2	1.8	1.4	1.4	1.5	1.7	1.3	1.5	2.0	1.9	1.6	-2.2
Age at first live birth	1.7	3.0	4.7	-2.1	-1.4	-2.0	-1.5	-2.2	-2.0	-2.1	-1.7	-1.9	-2.1	-0.7	-0.4	-2.1	-0.6
Smoking status: Current	1.7	2.6	3.4	1.6	1.7	1.1	1.8	1.8	1.6	1.8	1.8	1.7	1.8	1.4	1.5	1.8	-1.0
Intelligence (Savage-Jansen 2018)	1.6	5.0	15.6	2.0	2.2	1.7	2.4	1.5	1.5	1.3	2.0	1.5	1.5	2.8	3.5	1.5	-4.0
Cardiovascular Disease	1.6	5.4	6.7	2.1	2.5	1.8	2.5	2.4	2.4	2.2	2.5	2.4	2.2	2.5	1.9	2.3	-2.6
Chronotype (morning person)	1.6	3.8	5.9	2.4	1.9	2.3	1.8	1.9	2.0	2.1	2.2	2.0	2.0	1.5	1.5	2.3	-0.5
Impedance of leg (left)	1.5	7.2	9.1	3.0	2.9	2.4	2.8	2.8	2.5	2.9	2.9	2.8	2.8	2.5	2.4	2.8	-1.3
Trunk fat-free mass	1.5	8.4	10.6	-3.3	-3.1	-1.9	-3.0	-3.1	-3.0	-3.2	-3.2	-3.2	-3.0	-2.7	-2.7	-3.1	1.3
Ever highly irritable/argumentative for 2 days	1.5	1.7	3.3	1.5	1.3	1.8	1.4	1.6	1.3	1.4	1.3	1.1	1.4	1.0	1.0	1.5	-0.4
Qualifications: College or University degree	1.5	4.6	5.8	-2.0	-2.4	-2.1	-2.3	-2.3	-2.1	-2.3	-2.2	-2.4	-2.3	-2.1	-1.5	-2.2	1.5
Pulse rate, automated reading	1.5	4.8	28.3	-0.9	-1.8	0.8	-1.7	0.1	0.4	0.2	-0.7	-0.8	-0.2	-3.6	-5.3	0.0	4.0
Illnesses of father: Heart disease	1.5	2.1	4.0	1.1	1.6	1.2	1.6	1.2	1.1	1.1	1.4	1.3	1.3	1.8	1.7	1.2	-2.0
Back pain experienced in last month	1.5	2.2	3.5	-1.6	-1.5	-1.4	-1.4	-1.5	-1.6	-1.6	-1.4	-1.5	-1.9	-1.3	-1.2	-1.7	0.6
Bipolar Disorder (2011)	1.4	1.4	6.3	0.5	1.2	0.2	1.2	0.5	0.4	0.4	0.8	0.8	0.5	1.9	1.9	0.5	-2.5
Type 2 Diabetes (T2D) (2018)	1.4	2.6	6.8	1.4	1.6	2.6	1.6	1.5	2.0	1.5	1.6	1.6	1.5	1.5	0.9	1.6	-1.3
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	2.8	-1.1	-1.4	-1.1	-1.3	-1.2	-1.7	-1.3	-1.4	-1.3	-1.3	-1.2	-1.4	-1.1	0.9
Peak expiratory flow (PEF)	1.4	3.4	5.9	-2.2	-1.6	-1.7	-1.7	-2.3	-2.2	-2.3	-1.6	-1.8	-2.4	-0.9	-0.5	-2.3	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.9	3.6	1.4	1.5	0.9	1.6	1.3	1.0	1.2	1.5	1.2	1.0	1.7	1.4	1.2	-1.9
Mouth/teeth dental problems: Loose teeth	1.4	1.6	4.2	0.9	1.5	1.2	1.3	0.8	0.6	0.9	1.2	1.3	0.9	1.8	1.7	1.0	-2.1
Whole body fat-free mass	1.4	7.8	9.7	-3.1	-3.0	-1.8	-3.0	-3.0	-2.8	-3.1	-3.1	-3.1	-3.0	-2.6	-2.6	-3.0	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.7	2.7	1.4	1.4	1.1	1.4	1.6	1.4	1.4	1.2	1.6	1.4	1.2	0.6	1.4	-0.8
Whole body water mass	1.4	7.8	9.7	-3.1	-3.0	-1.8	-2.9	-3.0	-2.8	-3.1	-3.1	-3.1	-3.0	-2.6	-2.6	-3.0	1.2
Financial situation satisfaction	1.4	1.7	2.7	1.0	1.5	1.2	1.4	1.2	1.2	1.4	1.4	1.1	1.2	1.4	1.6	1.3	-1.4
Medication: Bendroflumethiazide	1.4	2.2	3.2	1.2	1.7	0.7	1.6	1.4	1.5	1.4	1.7	1.4	1.5	1.8	1.6	1.3	-1.6
Reaction Time	1.3	2.4	11.3	1.4	0.0	0.6	0.1	1.5	1.6	1.6	0.6	0.8	1.4	-1.4	-2.4	1.5	3.4
Impedance of leg (right)	1.3	6.3	8.0	2.8	2.7	2.2	2.6	2.6	2.4	2.7	2.7	2.7	2.5	2.5	2.5	2.6	-1.2
High blood pressure	1.3	3.7	4.8	1.8	2.1	1.1	2.1	1.9	2.0	1.8	2.0	2.2	1.8	2.2	1.7	1.8	-2.1
Qualifications: None of the above	1.3	2.9	3.6	1.7	1.8	1.8	1.8	1.8	1.8	1.8	1.7	1.7	1.7	1.7	1.2	1.9	-1.2
Hair/balding pattern: Pattern 3	1.3	2.0	3.7	-1.6	-1.1	-1.9	-1.3	-1.7	-1.5	-1.7	-1.4	-1.6	-1.7	-0.6	-0.4	-1.6	-0.3
Trunk predicted mass	1.3	7.6	9.8	-3.1	-3.0	-1.8	-2.9	-3.0	-2.8	-3.0	-3.0	-3.1	-2.9	-2.5	-2.6	-3.0	1.2
Medication: Omeprazole	1.3	1.5	2.5	-1.2	-1.3	-1.3	-1.2	-1.0	-1.2	-1.0	-1.2	-1.1	-1.1	-1.4	-1.6	-1.0	1.3
Alcohol intake frequency.	1.3	2.9	10.8	1.1	1.8	1.2	1.6	0.6	1.1	0.8	1.6	1.2	0.6	2.6	2.7	0.9	-3.3
Hypertension (Self-reported)	1.3	3.7	4.8	1.8	2.1	1.0	2.1	1.9	2.0	1.8	2.1	2.1	1.7	2.2	1.8	1.8	-2.1
Smoking status: Previous	1.3	2.0	2.9	1.4	1.4	1.1	1.5	1.7	1.6	1.6	1.5	1.7	1.5	1.2	0.8	1.6	-0.7
Long-standing illness, disability or infirmity	1.3	1.9	5.2	1.1	1.5	0.5	1.6	1.1	1.5	1.0	1.2	1.0	1.0	1.8	2.0	1.1	-2.3
Height	1.2	24.1	30.5	-5.0	-5.2	-3.5	-5.3	-5.3	-5.2	-5.2	-5.3	-5.5	-4.9	-4.7	-4.3	-5.2	3.5
Ever had hysterectomy (womb removed)	1.2	1.4	2.3	-1.2	-1.1	-1.4	-1.2	-1.0	-0.9	-1.0	-0.8	-1.2	-1.1	-1.3	-1.5	-1.1	1.3
Chronic bronchitis/emphysema (father)	1.2	1.4	2.4	-1.1	-1.3	-1.2	-1.2	-0.9	-1.0	-1.0	-1.2	-1.1	-1.0	-1.4	-1.5	-1.0	1.5
Standing height	1.2	11.6	15.8	-3.6	-3.6	-2.2	-3.6	-3.9	-3.6	-3.8	-3.8	-4.0	-3.7	-3.1	-2.7	-3.7	1.7
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	5.3	-1.8	-1.4	-2.3	-1.4	-1.6	-1.6	-1.6	-1.6	-1.6	-1.5	-1.0	-1.2	-1.6	0.1
Arm fat-free mass (right)	1.2	6.0	7.6	-2.8	-2.6	-1.6	-2.5	-2.6	-2.5	-2.7	-2.6	-2.7	-2.7	-2.2	-2.4	-2.6	0.8
Pulse wave peak to peak time	1.2	1.4	3.3	-1.2	-1.2	-0.9	-1.1	-1.4	-1.8	-1.6	-1.2	-1.2	-1.4	-0.6	-0.2	-1.5	-0.1
Medication: Blood pressure	1.2	2.1	3.4	1.0	1.6	1.0	1.6	1.2	1.4	1.2	1.6	1.5	1.2	1.8	1.7	1.3	-1.8
Irritability	1.2	2.1	3.7	1.3	1.5	0.2	1.7	1.4	1.2	1.3	1.2	1.9	1.3	1.8	1.7	1.4	-1.5
Supplements: Calcium	1.2	1.3	2.6	-1.2	-1.0	-1.2	-1.2	-1.4	-1.6	-1.3	-1.2	-1.0	-1.4	-0.7	-0.9	-1.3	0.3
Body Mass Index (BMI) (2010)	1.1	1.6	2.1	1.3	1.2	1.3	1.2	1.4	1.4	1.4	1.2	1.3	1.4	0.9	0.8	1.4	-0.5
Current tobacco smoking	1.1	1.8	2.5	1.2	1.5	0.6	1.6	1.6	1.3	1.5	1.5	1.4	1.5	1.2	1.2	1.5	-0.9
Had menopause	1.1	1.4	2.1	-0.9	-1.3	-1.1	-1.2	-1.0	-0.9	-1.0	-1.1	-1.2	-1.1	-1.4	-1.4	-1.1	1.3
Happiness	1.1	1.3	2.9	0.9	1.2	0.3	1.2	0.8	1.0	1.0	1.1	1.0	1.1	1.5	1.7	1.0	-1.5
Number of children fathered	1.1	1.2	2.0	-1.4	-0.7	-1.4	-0.8	-1.4	-1.4	-1.3	-0.9	-1.3	-1.4	0.0	0.2	-1.1	-0.9
Arm predicted mass (right)	1.1	5.7	7.2	-2.7	-2.5	-1.5	-2.5	-2.6	-2.5	-2.6	-2.6	-2.6	-2.6	-2.1	-2.3	-2.5	0.8
Medication: Aspirin	1.1	1.5	2.7	0.9	1.2	1.5	1.1	1.1	1.6	1.3	1.3	1.5	1.2	1.1	0.8	1.3	-0.4
Diabetes diagnosed by doctor	1.1	1.8	3.9	1.1	1.3	1.7	1.3	1.3	2.0	1.4	1.4	1.5	1.2	1.2	0.7	1.4	-0.8
Friendships satisfaction	1.1	1.4	4.5	0.9	1.2	0.8	1.3	0.7	0.5	0.7	0.9	0.9	0.9	1.7	1.9	0.8	-2.1
Arm fat-free mass (left)	1.1	5.4	6.8	-2.5	-2.5	-1.4	-2.5	-2.4	-2.3	-2.5	-2.6	-2.5	-2.4	-2.3	-2.6	-2.4	1.3
Average weekly beer plus cider intake	1.1	1.5	2.7	1.4	1.1	1.5	1.3	1.6	1.1	1.6	1.1	1.2	1.5	0.6	0.5	1.6	-0.1
Vascular/heart problems diagnosed by doctor	1.1	2.9	3.6	-1.6	-1.9	-1.0	-1.8	-1.7	-1.9	-1.6	-1.8	-1.9	-1.6	-1.9	-1.5	-1.6	1.8
Systolic blood pressure, automated reading	1.0	2.9	6.9	1.3	1.9	-0.3	1.8	1.2	1.3	1.1	1.6	1.8	1.3	2.4	2.6	1.2	-2.5
Leg fat-free mass (left)	1.0	5.1	6.6	-2.5	-2.5	-1.3	-2.5	-2.5	-2.2	-2.5	-2.6	-2.4	-2.4	-2.2	-2.2	-2.4	1.0
Stomach or abdominal pain in last month	1.0	1.3	4.8	0.9	1.2	0.5	1.1	0.5	0.5	0.6	1.1	0.9	0.4	1.7	1.7	0.8	-2.2
Leg predicted mass (left)	1.0	5.5	7.0	-2.6	-2.5	-1.3	-2.5	-2.6	-2.3	-2.6	-2.6	-2.5	-2.5	-2.2	-2.3	-2.5	1.1
Mouth/teeth dental problems	1.0	1.5	2.8	-1.0	-1.5	-0.5	-1.3	-0.9	-1.0	-1.1	-1.3	-0.9	-1.0	-1.7	-1.7	-1.2	1.6
Exposure to tobacco smoke at home	1.0	1.1	1.6	1.2	1.0	0.7	1.2	1.3	1.2	1.1	1.0	1.1	1.1	0.9	0.5	1.1	-0.8
Hair/balding pattern: Pattern 4	1.0	2.4	3.7	-1.6	-1.6	-0.7	-1.6	-1.9	-1.7	-1.8	-1.7	-1.9	-1.8	-1.2	-0.9	-1.8	0.5
Medication: Paracetamol	1.0	1.7	3.4	-0.9	-1.5	-0.9	-1.4	-1.0	-1.1	-1.1	-1.3	-1.0	-1.3	-1.6	-1.7	-1.1	1.9
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	2.7	-0.8	-1.4	-0.7	-1.4	-1.0	-1.4	-1.1	-1.4	-1.4	-1.0	-1.6	-1.6	-1.1	1.6
Comparative body size at age 10	1.0	2.7	6.1	-1.6	-1.8	-1.0	-1.8	-1.3	-1.1	-1.2	-1.6	-1.5	-1.3	-2.1	-2.5	-1.3	2.3
Leg pain on walking	1.0	1.3	2.3	-1.3	-1.0	-0.9	-1.0	-1.4	-1.1	-1.5	-1.3	-1.3	-1.5	-0.4	-0.4	-1.5	-0.4
Leg fat-free mass (right)	1.0	5.4	6.9	-2.6	-2.5	-1.3	-2.5	-2.5	-2.3	-2.6	-2.6	-2.6	-2.5	-2.2	-2.3	-2.5	1.0
Leg predicted mass (right)	1.0	5.2	6.6	-2.5	-2.5	-1.3	-2.4	-2.5	-2.2	-2.5	-2.6	-2.5	-2.4	-2.2	-2.2	-2.4	1.0
Basal metabolic rate	1.0	5.5	6.9	-2.6	-2.5	-1.3	-2.5	-2.5	-2.3	-2.5	-2.6	-2.5	-2.4	-2.3	-2.5	-2.4	1.2
Verbal and Numeric Reasoning (VNR)	0.9	2.1	8.7	0.9	1.3	1.0	1.4	0.6	0.7	0.5	1.1	1.0	0.7	1.9	2.8	0.6	-2.9
Neuroticism	0.9	2.2	2.9	-1.6	-1.6	-1.6	-1.5	-1.4	-1.6	-1.5	-1.7	-1.4	-1.5	-1.3	-1.3	-1.6	1.1
Number of incorrect matches in round	0.9	1.6	4.2	-0.7	-1.3	-1.6	-1.2	-0.7	-0.5	-0.8	-1.2	-1.3	-0.8	-1.7	-1.7	-0.8	2.0
Pulse wave Arterial Stiffness index	0.9	1.0	2.6	1.0	0.9	0.7	0.8	1.2	1.6	1.3	1.0	0.9	1.2	0.3	-0.0	1.3	0.3
Tense / ‘highly strung’	0.9	1.5	2.2	1.3	1.4	0.0	1.5	1.2	1.1	1.2	1.4	1.1	1.1	1.5	1.3	1.3	-1.3
Medication: Ventolin 100micrograms inhaler	0.9	1.2	2.3	1.0	1.0	0.3	1.1	0.9	1.0	0.8	1.0	1.5	0.7	1.4	1.5	1.0	-1.3
Shortness of breath walking on level ground	0.9	1.0	2.6	0.9	1.0	0.8	1.1	0.8	0.8	0.7	0.8	0.9	0.8	1.3	1.4	0.8	-1.6
Medication: Seretide 50 evohaler	0.9	1.0	2.5	0.7	1.1	0.8	1.1	0.8	0.6	0.7	0.7	0.9	0.8	1.2	1.5	0.8	-1.6
Chest pain or discomfort	0.9	1.3	2.2	1.1	1.2	0.6	1.3	1.1	1.1	1.1	1.1	1.1	1.2	1.2	1.5	1.1	-1.3
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.8	-0.9	-1.1	-0.7	-1.2	-0.9	-0.8	-0.7	-1.0	-0.7	-0.8	-1.3	-1.7	-0.7	1.6
Medication: Aspirin	0.9	1.1	2.7	0.8	1.0	1.4	0.9	1.0	1.6	1.2	1.2	1.2	1.1	0.7	0.4	1.2	0.1
Commuting to job workplace: Public transport	0.9	1.1	1.7	1.1	1.1	0.2	1.2	1.2	1.2	1.1	0.8	1.0	1.3	1.0	1.0	1.1	-1.0
Leg fat percentage (left)	0.9	3.1	5.2	1.7	1.6	2.2	1.4	2.0	2.3	2.2	1.7	2.2	1.9	0.9	0.1	2.3	0.3
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	1.4	-1.1	-1.1	-1.1	-1.0	-0.9	-1.2	-0.9	-1.0	-1.0	-1.1	-1.1	-1.2	-0.9	1.0
Arm predicted mass (left)	0.9	4.7	5.9	-2.4	-2.3	-1.3	-2.3	-2.2	-2.1	-2.3	-2.4	-2.3	-2.2	-2.1	-2.4	-2.2	1.2
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.7	0.6	1.1	0.5	1.2	0.6	0.6	0.6	0.9	0.9	0.7	1.6	1.6	0.7	-1.9
Alcohol usually taken with meals	0.8	1.3	2.2	-1.4	-1.1	-0.5	-1.3	-1.5	-1.1	-1.4	-1.2	-1.2	-1.4	-0.8	-0.6	-1.4	0.2
Loud music exposure frequency	0.8	0.9	2.0	1.0	0.9	0.9	0.9	1.1	1.4	1.1	1.0	1.0	1.1	0.6	0.2	1.1	-0.2
Glaucoma (self-reported)	0.8	0.9	2.7	-0.8	-0.9	-0.8	-0.9	-0.3	0.0	-0.4	-0.8	-0.8	-0.7	-1.5	-1.6	-0.5	1.6
Exposure to tobacco smoke outside home	0.8	1.1	2.3	0.9	1.0	1.5	1.0	1.1	1.0	1.1	1.0	1.1	1.2	1.0	0.7	1.1	-0.7
Overall health rating	0.8	1.8	7.7	0.7	1.4	0.4	1.5	0.7	0.7	0.7	1.0	0.9	0.6	1.9	2.0	0.8	-2.8
Illnesses of siblings: Diabetes	0.8	1.0	2.4	1.1	0.5	1.3	0.5	1.1	1.6	1.1	0.6	1.1	1.0	-0.1	-0.9	1.2	0.8
Wears glasses or contact lenses	0.8	0.9	1.3	1.1	1.0	0.1	1.0	1.1	0.8	1.1	1.1	0.7	1.1	0.9	0.9	1.1	-0.7
Mother’s age at death	0.8	1.0	3.0	-0.8	-1.0	-0.2	-1.1	-0.7	-0.5	-0.6	-0.7	-0.6	-0.8	-1.3	-1.7	-0.7	1.6
Triglycerides	0.7	1.1	1.8	0.8	1.0	1.4	1.0	1.1	1.2	1.3	1.2	1.2	1.2	0.8	0.4	1.1	-0.4
Hypothyroidism (self reported)	0.7	1.6	4.1	-1.5	-1.1	-2.0	-1.1	-1.2	-1.2	-1.3	-1.2	-1.4	-1.3	-0.9	-1.2	-1.3	-0.0
Sensitivity / hurt feelings	0.7	1.2	1.7	-1.0	-1.1	-1.1	-1.1	-1.1	-0.9	-0.9	-1.1	-0.9	-0.9	-1.1	-1.3	-1.0	1.3
Medication for hormone replacement therapy	0.7	0.8	1.1	-0.8	-0.9	-0.7	-1.0	-0.9	-0.8	-0.9	-1.0	-0.4	-0.9	-0.9	-1.0	-0.9	1.0
Pack years adult smoking proportion	0.7	1.1	2.1	1.2	0.9	1.1	1.1	1.5	1.1	1.4	1.0	0.9	1.4	0.3	0.3	1.4	0.4
Leg fat percentage (right)	0.7	2.7	4.7	1.6	1.4	2.0	1.3	1.8	2.2	2.0	1.5	2.1	1.8	0.8	0.1	2.1	0.3
Eye problems/disorders: None of the above	0.7	0.8	1.3	-0.9	-0.7	-1.1	-0.7	-1.1	-1.1	-1.1	-0.7	-0.8	-0.9	-0.1	-0.2	-1.1	-0.6
Heart disease (mother)	0.7	0.8	3.1	0.5	1.0	1.0	0.8	0.3	0.6	0.4	0.7	0.5	0.2	1.4	1.4	0.4	-1.8
Risk taking	0.7	1.0	1.7	1.0	0.9	1.2	1.0	1.3	1.0	1.2	1.0	1.0	1.2	0.4	-0.1	1.3	-0.1
Pack years of smoking	0.7	1.1	1.9	1.1	0.9	1.1	1.0	1.4	1.1	1.3	0.9	0.9	1.4	0.4	0.4	1.3	0.3
Rheumatoid Arthritis	0.6	0.8	2.0	-1.0	-0.9	-0.2	-0.9	-1.1	-0.8	-1.1	-0.7	-1.4	-1.0	-0.8	-0.5	-1.0	0.2
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.5	0.6	0.8	0.8	0.9	0.9	1.2	0.8	0.8	0.5	0.8	0.7	0.8	0.8	-0.8
Medication: Ramipril	0.6	0.7	1.3	0.8	0.9	0.8	0.9	0.6	1.0	0.6	0.8	0.6	0.7	1.0	1.0	0.8	-1.1
Worrier / anxious feelings	0.6	1.2	2.4	1.2	1.1	0.5	1.1	1.3	1.4	1.3	1.1	1.5	1.3	0.8	0.5	1.3	0.0
Pulse rate	0.6	1.1	6.7	-0.6	-1.0	0.4	-0.9	-0.1	0.2	-0.1	-0.6	-0.6	-0.4	-1.6	-2.6	-0.3	1.5
Noisy workplace	0.6	0.7	3.2	0.1	0.8	0.8	0.8	0.2	0.4	0.2	0.5	0.5	0.0	1.4	1.5	0.3	-1.8
Qualifications: A levels/AS levels or equivalent	0.6	1.4	1.9	-1.2	-1.3	-1.3	-1.2	-1.3	-1.1	-1.4	-1.4	-1.4	-1.1	-1.1	-0.4	-1.3	0.6
Eye problems/disorders: Cataract	0.6	0.7	1.7	-0.6	-0.9	-0.2	-0.9	-0.7	-0.8	-0.8	-1.3	-1.1	-0.7	-1.0	-0.6	-0.9	1.0
Alcohol drinker status: Previous	0.6	0.6	3.2	0.6	0.7	0.7	0.8	0.4	0.4	0.2	0.6	0.3	0.2	1.1	1.4	0.2	-1.8
Impedance of whole body	0.6	3.1	4.6	2.1	1.8	1.6	1.8	1.8	1.7	2.0	1.9	1.8	1.8	1.5	1.7	1.9	-0.4
Crohns Disease (2017)	0.5	1.0	2.5	1.1	0.7	1.1	0.7	1.2	1.6	1.3	0.8	0.9	1.1	0.0	-0.5	1.2	0.6
Irritable Bowel Disease (IBD)	0.5	1.2	2.4	1.3	0.6	1.3	0.7	1.4	1.6	1.4	0.8	1.0	1.2	-0.2	-1.1	1.3	1.1
Ovarian Cancer	0.5	0.7	2.5	0.4	0.8	0.7	0.8	0.6	0.6	0.5	0.8	0.4	0.4	1.0	1.4	0.5	-1.6
Prostate Cancer	0.5	0.7	1.3	0.8	0.9	0.3	0.9	0.8	0.8	0.7	0.9	0.7	0.7	0.9	0.9	0.9	-1.2
Age at First Birth	0.5	0.7	2.1	0.8	0.9	-0.3	0.9	0.5	0.4	0.5	0.9	0.6	0.4	1.2	1.4	0.6	-1.3
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	3.9	0.1	0.6	-0.7	0.7	0.1	0.4	0.1	0.5	0.2	0.0	1.1	1.2	0.1	-2.0
Average weekly fortified wine intake	0.5	0.5	1.1	0.7	0.8	0.8	0.8	0.6	0.3	0.6	0.8	0.3	0.8	0.7	1.0	0.5	-1.0
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.7	-0.6	-0.6	-0.8	-0.7	-0.3	-0.3	-0.3	-0.3	-0.9	-0.4	-1.1	-1.3	-0.5	1.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.1	1.0	0.6	1.0	0.6	0.9	1.0	1.0	0.7	1.0	0.8	0.3	0.2	0.9	0.1
Medication: Atenolol	0.5	0.7	2.2	-0.6	-0.8	-0.1	-0.9	-0.5	-0.2	-0.4	-0.6	-0.8	-0.4	-1.3	-1.4	-0.5	1.5
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.1	0.8	0.9	0.2	0.8	0.7	0.8	0.8	0.8	0.9	0.5	0.8	1.1	0.7	-0.8
Fluid intelligence score	0.5	1.0	4.2	0.5	0.8	0.2	0.9	0.3	0.1	0.2	0.7	0.7	0.5	1.4	2.1	0.3	-2.1
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	1.6	-1.1	-0.8	-0.8	-0.9	-1.1	-1.0	-1.1	-1.0	-1.2	-1.0	-0.7	-0.3	-1.2	0.1
Health satisfaction	0.5	0.6	1.8	0.2	0.8	0.2	0.8	0.5	0.8	0.4	0.7	0.6	0.6	1.1	1.3	0.5	-1.3
Unable to work because of sickness or disability	0.5	0.6	1.9	0.5	0.8	0.2	0.9	0.6	0.4	0.4	0.7	0.7	0.5	1.2	1.3	0.4	-1.4
Commuting to job workplace: Cycle	0.5	0.6	1.3	-0.6	-1.0	-0.0	-0.8	-0.5	-0.7	-0.7	-0.8	-0.8	-0.5	-1.1	-1.0	-0.6	1.1
Neuroticism (Nagel 2018)	0.4	1.0	2.2	-1.0	-0.9	-1.5	-1.0	-1.2	-1.1	-0.9	-1.0	-0.8	-1.1	-0.7	-0.8	-0.9	0.6
Breast Cancer	0.4	1.1	2.5	-1.1	-1.1	-0.9	-1.2	-1.0	-0.8	-0.9	-1.0	-1.0	-0.7	-1.3	-0.6	-0.9	1.6
Ulcerative Colitis	0.4	0.6	1.4	1.0	0.6	0.7	0.8	1.0	1.2	0.9	0.9	0.8	0.8	0.5	-0.3	0.9	-0.1
Smoking Status	0.4	1.0	1.9	0.8	1.0	0.5	1.2	1.4	1.2	1.3	1.1	1.3	1.2	0.5	0.3	1.2	-0.3
Hand grip strength (right)	0.4	1.0	1.9	-1.0	-1.1	-0.4	-1.0	-0.9	-1.2	-1.1	-0.8	-1.4	-1.1	-1.0	-1.0	-1.1	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	2.5	-0.6	-0.0	-0.9	-0.0	-0.6	-0.6	-0.7	-0.3	-0.4	-0.7	0.6	0.5	-0.7	-1.6
Taking other prescription medications	0.4	0.6	2.2	-0.9	-0.7	-1.5	-0.6	-0.5	-0.4	-0.6	-0.6	-0.7	-0.9	-0.5	-0.7	-0.7	0.1
Qualifications: CSEs or equivalent	0.4	0.6	1.4	0.2	0.7	0.9	0.7	0.5	0.4	0.4	0.6	1.0	0.5	1.0	1.1	0.3	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	4.5	-0.0	0.5	-0.7	0.5	-0.2	-0.5	-0.4	0.1	-0.1	-0.1	1.1	1.3	-0.2	-2.1
Hair/balding pattern: Pattern 2	0.4	0.5	1.6	0.7	0.6	0.6	0.7	0.9	0.8	0.7	0.7	1.3	0.6	0.5	0.2	0.8	-0.2
Medication: Cholesterol lowering	0.4	0.6	1.6	0.4	0.9	0.8	0.8	0.5	0.8	0.5	0.9	0.7	0.5	1.1	1.1	0.6	-1.2
Prospective memory result	0.4	0.5	2.8	0.5	0.2	0.3	0.1	0.7	0.7	0.8	0.4	0.2	0.7	-0.5	-0.8	0.8	1.7
Gout (self-reported)	0.4	0.5	1.4	0.6	0.7	0.9	0.7	0.6	0.4	0.6	0.7	0.6	0.7	0.9	1.2	0.6	-0.9
Number of full brothers	0.4	0.5	1.3	0.8	0.6	1.1	0.5	0.8	0.9	0.9	0.6	0.9	0.8	0.3	-0.3	0.8	0.1
Medication: Allopurinol	0.4	0.6	1.6	0.4	0.7	0.9	0.7	0.4	0.3	0.4	0.6	0.6	0.5	1.0	1.2	0.5	-1.3
Supplements: Vitamin C	0.4	0.5	1.0	-0.7	-0.7	-0.8	-0.8	-0.7	-1.0	-0.7	-0.5	-0.6	-0.7	-0.8	-0.8	-0.6	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	0.8	-0.4	-0.7	-0.9	-0.5	-0.5	-0.7	-0.6	-0.9	-0.7	-0.6	-0.6	-0.8	-0.7	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	1.6	-1.0	-0.7	-0.4	-0.8	-1.2	-1.3	-1.2	-1.0	-1.1	-1.1	-0.3	-0.1	-1.2	-0.5
Breast cancer (self-reported)	0.4	0.5	0.8	0.6	0.7	0.8	0.6	0.7	0.7	0.8	0.7	0.7	0.7	0.5	0.5	0.9	-0.1
Osteoporosis (self-reported)	0.4	0.6	1.0	-0.7	-0.7	-0.7	-0.6	-0.7	-1.0	-0.9	-0.8	-0.8	-0.8	-0.6	-0.6	-0.9	-0.1
Illnesses of father: None of the above (group 1)	0.4	0.5	2.3	0.6	-0.0	0.9	0.1	0.6	0.4	0.7	0.3	0.4	0.7	-0.6	-0.6	0.6	1.5
Number of self-reported non-cancer illnesses	0.4	0.7	1.3	0.7	0.8	-0.1	0.9	1.0	1.1	0.9	1.0	0.9	0.7	0.7	0.1	0.9	-0.8
Ever taken oral contraceptive pill	0.4	0.4	0.7	-0.8	-0.7	-0.6	-0.7	-0.7	-0.8	-0.7	-0.5	-0.7	-0.7	-0.5	-0.6	-0.8	0.4
Eye problems/disorders: Glaucoma	0.4	0.4	1.9	-0.6	-0.6	-0.3	-0.6	-0.1	0.2	-0.1	-0.5	-0.4	-0.3	-1.1	-1.2	-0.3	1.4
High cholesterol (Self-reported)	0.4	0.8	1.2	0.5	0.9	1.0	1.0	0.9	0.7	0.7	0.9	0.8	0.9	0.9	0.8	0.8	-1.1
Medication: Paracetamol	0.4	0.6	0.9	-0.4	-0.9	-0.6	-0.8	-0.6	-0.8	-0.8	-0.9	-0.6	-0.9	-0.8	-0.9	-0.7	0.8
Alcohol drinker status: Never	0.4	0.5	2.6	-0.6	0.2	-0.3	-0.0	-0.9	-0.3	-0.6	0.1	-0.3	-0.7	0.9	1.2	-0.6	-1.6
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.4	0.5	0.7	1.0	0.5	0.3	0.6	0.4	0.5	0.6	0.3	1.0	0.8	0.4	-1.2
Ulcerative Colitis (UC)	0.3	0.6	1.2	0.9	0.2	0.7	0.4	1.0	0.9	0.9	0.6	0.6	0.7	-0.3	-1.1	0.9	1.1
Coronary Artery Disease (CAD)	0.3	0.4	0.7	0.6	0.6	0.8	0.6	0.6	0.4	0.6	0.7	0.5	0.8	0.6	0.6	0.7	-0.6
Neuroticism (2016)	0.3	0.4	0.7	-0.8	-0.7	-0.4	-0.7	-0.7	-0.5	-0.6	-0.7	-0.7	-0.6	-0.5	-0.8	-0.8	0.5
Hearing difficulty/problems: Yes	0.3	0.4	1.9	-0.3	0.1	-1.1	0.1	-0.4	-0.3	-0.5	-0.3	-0.4	-0.6	0.5	0.9	-0.4	-1.4
Severe depression (siblings)	0.3	0.4	0.8	-0.9	-0.6	-0.3	-0.6	-0.7	-0.8	-0.8	-0.6	-0.4	-0.7	-0.4	-0.4	-0.6	0.3
Fed-up feelings	0.3	0.6	1.3	-0.9	-0.6	-1.1	-0.5	-0.9	-0.9	-1.0	-1.0	-0.4	-0.9	-0.1	-0.1	-1.1	-0.4
Age when periods started (menarche)	0.3	0.6	1.3	0.6	1.0	0.4	0.9	0.4	0.7	0.6	0.7	0.7	0.7	1.2	1.1	0.6	-1.0
Sitting height	0.3	1.9	3.0	-1.4	-1.5	-0.1	-1.5	-1.4	-1.2	-1.4	-1.5	-1.5	-1.3	-1.6	-1.7	-1.3	1.3
Nervous feelings	0.3	0.5	0.8	-0.5	-0.8	-0.7	-0.8	-0.8	-0.7	-0.8	-0.9	-0.7	-0.8	-0.6	-0.7	-0.8	0.6
Hearing difficulty/problems with background noise	0.3	0.5	3.6	0.1	0.4	-0.5	0.6	-0.1	-0.0	-0.2	0.1	-0.2	-0.1	0.9	1.4	-0.2	-1.9
Weight	0.3	1.7	3.6	-1.4	-1.5	-0.2	-1.5	-1.2	-1.0	-1.2	-1.5	-1.2	-1.2	-1.6	-1.9	-1.0	1.2
Impedance of arm (right)	0.3	1.4	2.3	1.5	1.2	1.1	1.2	1.3	1.2	1.4	1.2	1.3	1.4	0.8	1.1	1.3	0.2
Arm fat percentage (right)	0.3	1.3	2.7	0.9	0.8	1.6	0.7	1.2	1.6	1.4	0.9	1.4	1.3	0.2	-0.3	1.5	0.7
Breastfed as a baby	0.3	0.4	0.7	-0.6	-0.4	-0.5	-0.6	-0.8	-0.8	-0.8	-0.4	-0.6	-0.9	-0.2	0.1	-0.7	-0.0
Birth weight of first child	0.3	0.6	3.6	0.9	0.5	1.9	0.5	0.8	0.4	0.7	0.8	0.9	0.7	0.3	-0.1	0.8	0.3
Body fat percentage	0.3	1.3	3.1	1.0	0.8	1.8	0.6	1.2	1.5	1.4	0.9	1.3	1.2	0.2	-0.4	1.5	0.8
Neck or shoulder pain in last month	0.3	0.4	1.5	-0.5	-0.2	-1.2	-0.1	-0.5	-0.7	-0.6	-0.4	-0.7	-0.7	0.0	0.3	-0.7	-0.9
Migraine (self-reported)	0.3	0.4	1.0	0.8	0.4	1.0	0.3	0.5	0.7	0.7	0.7	0.8	0.5	0.2	0.2	0.6	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	2.0	-0.4	0.4	-0.4	0.2	-0.2	0.0	-0.2	0.3	0.2	-0.2	0.9	0.9	-0.2	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.3	-0.8	-0.5	-1.1	-0.6	-0.9	-0.7	-0.7	-0.4	-0.6	-1.0	-0.1	0.3	-0.7	-0.3
Ever smoked	0.3	0.6	1.2	0.8	0.7	0.0	0.9	1.1	1.1	1.0	0.7	0.8	0.9	0.3	0.1	1.0	-0.1
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.5	-0.6	-0.5	-0.1	-0.6	-0.5	-0.6	-0.4	-0.4	-0.7	-0.7	-0.6	-0.4	-0.5	0.7
Myopia	0.3	0.4	2.0	0.5	0.5	0.6	0.6	0.2	0.6	0.2	0.3	0.4	0.4	0.8	1.2	0.3	-1.4
Depression (Nagel 2018)	0.2	0.2	1.3	-0.4	0.1	-0.7	0.1	-0.4	-0.4	-0.4	-0.0	-0.2	-0.5	0.5	0.4	-0.3	-1.1
Schizophrenia vs Biploar Disorder	0.2	0.3	1.1	-0.3	-0.4	-0.9	-0.5	-0.2	-0.2	-0.1	-0.4	0.1	-0.3	-0.5	-0.7	-0.4	1.1
Crohns Disease (2012)	0.2	0.4	1.2	0.5	0.1	0.8	0.0	0.5	0.8	0.6	0.1	0.3	0.6	-0.5	-0.8	0.4	1.1
Mean Putamen Volume	0.2	0.2	0.6	-0.2	-0.5	-0.5	-0.4	-0.4	-0.2	-0.4	-0.5	-0.8	-0.3	-0.5	-0.4	-0.4	0.2
Blood Eosinophil Count	0.2	1.7	2.9	1.7	1.4	1.6	1.3	1.2	1.3	1.3	1.2	1.4	1.2	1.3	1.2	1.4	-0.9
Blood Red Count	0.2	1.5	3.5	-1.1	-1.3	-1.4	-1.3	-1.0	-0.3	-1.0	-1.3	-1.2	-0.9	-1.6	-1.9	-1.0	1.3
Hair Pigment	0.2	5.7	11.8	-2.0	-2.6	-1.8	-2.6	-1.8	-1.4	-1.8	-2.4	-2.4	-1.7	-3.1	-3.3	-1.8	3.4
Hand grip strength (left)	0.2	0.6	1.2	-1.1	-0.6	-0.8	-0.7	-0.9	-1.0	-0.9	-0.5	-1.1	-1.1	-0.4	-0.6	-1.0	-0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.5	0.2	-0.3	-0.1	-0.3	0.0	0.1	0.1	-0.1	-0.3	-0.1	-0.6	-0.8	-0.1	1.2
Medication: Co-codamol	0.2	0.3	0.7	-0.8	-0.4	-0.6	-0.3	-0.5	-0.4	-0.6	-0.6	-0.7	-0.7	-0.1	0.1	-0.6	-0.3
Diabetes (father)	0.2	0.3	0.7	-0.6	-0.5	-0.3	-0.6	-0.6	-0.2	-0.6	-0.6	-0.3	-0.8	-0.4	-0.3	-0.6	0.3
Trunk fat percentage	0.2	0.8	2.3	0.7	0.5	1.5	0.3	0.9	1.1	1.1	0.6	1.0	0.9	-0.1	-0.5	1.2	0.9
Multivitamins +/- minerals	0.2	0.2	1.5	-0.1	0.3	-0.0	0.3	-0.1	-0.3	-0.2	0.3	-0.1	-0.3	0.6	0.8	-0.1	-1.2
Illnesses of siblings	0.2	0.3	0.9	-0.5	-0.4	-0.9	-0.5	-0.6	-0.6	-0.6	-0.4	-0.5	-0.5	-0.3	0.1	-0.6	0.1
Alcohol intake versus 10 years previously	0.2	0.3	1.2	-0.4	-0.1	-0.6	-0.0	-0.5	-0.7	-0.6	-0.4	-0.3	-0.6	0.5	0.5	-0.5	-1.1
Illnesses of mother	0.2	0.3	1.9	-0.3	-0.5	-0.1	-0.5	-0.2	-0.2	-0.1	-0.4	-0.2	-0.0	-0.8	-0.5	-0.1	1.4
Impedance of arm (left)	0.2	0.9	1.4	1.2	0.9	0.8	0.9	0.9	0.9	1.1	1.1	0.9	1.0	0.6	1.0	1.1	0.2
Length of working week for main job	0.2	0.3	1.3	0.2	-0.2	0.5	-0.2	0.3	0.3	0.2	-0.1	0.1	0.2	-0.8	-1.0	0.2	1.1
Blood clot in the leg (DVT)	0.2	0.3	1.0	0.3	0.5	0.7	0.3	0.1	0.4	0.2	0.3	0.4	0.2	0.8	0.6	0.2	-1.0
Family relationship satisfaction	0.2	0.2	0.5	-0.7	-0.5	-0.3	-0.4	-0.3	-0.5	-0.3	-0.4	-0.5	-0.4	-0.6	-0.3	-0.5	0.4
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.5	0.4	0.4	0.7	0.4	0.7	0.5	0.5	0.5	0.5	0.5	0.1	-0.2	0.5	0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.6	0.5	0.5	0.5	0.5	0.3	0.7	0.4	0.3	0.5	0.4	0.6	0.8	0.4	-0.3
Arm fat percentage (left)	0.2	0.9	2.0	0.7	0.6	1.4	0.4	1.0	1.3	1.1	0.8	1.1	1.0	0.1	-0.4	1.3	0.7
Ever had bowel cancer screening	0.2	0.2	0.8	0.4	0.5	0.5	0.5	0.3	0.3	0.3	0.5	0.3	0.3	0.6	0.7	0.4	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.7	-0.3	-0.2	-0.5	-0.1	-0.4	-0.6	-0.6	-0.6	-0.1	-0.5	0.3	0.3	-0.6	-0.8
Illnesses of father: High blood pressure	0.2	0.2	1.1	0.5	0.4	0.6	0.5	0.2	0.4	0.2	0.4	0.3	0.1	0.7	0.4	0.2	-1.1
Diastolic blood pressure, automated reading	0.2	0.6	2.2	-0.5	-0.8	-0.5	-0.8	-0.5	-0.4	-0.5	-0.8	-0.3	-0.4	-1.0	-1.5	-0.5	1.0
Ever depressed for a whole week	0.2	0.2	0.9	0.3	0.5	-0.1	0.5	0.2	0.5	0.2	0.3	0.3	0.1	0.7	0.8	0.2	-1.0
Major Depression (MDD)	0.1	0.1	0.4	-0.5	-0.2	-0.6	-0.3	-0.2	-0.1	-0.0	-0.0	-0.2	-0.2	-0.4	-0.6	-0.2	0.6
Fasting Glucose	0.1	0.1	0.5	-0.3	-0.4	-0.4	0.0	0.7	-0.6	-0.3	-0.3	0.1	-0.2	-0.0	-0.3	-0.4	-0.4
Primary Biliary Cirrhosis	0.1	0.1	1.2	0.2	-0.0	-1.1	-0.0	0.1	0.3	0.0	0.0	0.1	0.0	-0.1	-0.3	0.1	-0.1
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.5	-0.1	-0.3	-0.1	-0.3	-0.0	-0.2	-0.2	-0.2	-0.2	-0.2	-0.4	-0.7	-0.3	0.3
BMI	0.1	0.5	2.7	-0.6	-0.6	-0.4	-0.7	-0.1	0.1	-0.2	-0.6	-0.1	-0.2	-1.0	-1.6	-0.1	1.1
Waist Hip Ratio (WHR)	0.1	0.4	2.5	0.4	0.7	0.8	0.5	-0.1	0.3	0.2	0.5	0.3	0.1	1.0	0.7	-0.2	-1.6
Lung FEV1/FVC ratio	0.1	0.7	1.7	-0.8	-0.4	-0.3	-0.6	-1.2	-1.3	-1.2	-0.8	-0.6	-0.9	0.3	0.3	-1.1	-1.3
Tanning	0.1	1.4	3.6	-1.5	-1.1	-1.1	-1.0	-1.3	-1.9	-1.4	-1.1	-1.2	-1.5	-0.6	-0.2	-1.4	-0.4
Number of treatments/medications taken	0.1	0.2	0.4	0.1	0.5	-0.2	0.4	0.3	0.6	0.3	0.5	0.4	0.1	0.6	0.5	0.4	-0.6
Supplements: Zinc	0.1	0.1	0.8	-0.2	-0.4	-0.9	-0.3	-0.1	-0.4	-0.2	-0.3	-0.1	-0.2	-0.4	-0.4	-0.2	0.2
Diabetes (mother)	0.1	0.1	0.7	0.0	-0.2	0.3	-0.3	-0.1	0.2	0.1	-0.2	0.0	-0.1	-0.3	-0.8	0.1	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.2	0.1	-0.3	0.1	-0.3	-0.1	-0.3	-0.0	-0.3	0.1	0.1	-0.5	-0.8	0.0	1.1
Body mass index (BMI)	0.1	0.2	0.9	0.1	-0.0	0.7	-0.1	0.4	0.6	0.4	0.1	0.5	0.4	-0.4	-0.9	0.5	0.6
Trunk fat mass	0.1	0.4	1.6	-0.3	-0.4	0.8	-0.6	-0.2	0.2	-0.0	-0.4	-0.1	-0.1	-0.9	-1.3	0.1	1.2
Waist circumference	0.1	0.2	0.8	0.2	0.3	0.9	0.2	0.4	0.6	0.5	0.3	0.6	0.5	0.1	-0.3	0.6	-0.1
Medication: Simvastatin	0.1	0.1	0.5	-0.4	-0.3	-0.1	-0.4	-0.2	-0.0	-0.2	-0.3	-0.3	-0.3	-0.5	-0.6	-0.2	0.7
Neuroticism score	0.1	0.2	0.7	-0.4	-0.5	-0.9	-0.3	-0.3	-0.5	-0.4	-0.5	-0.2	-0.3	-0.3	-0.5	-0.4	0.4
Falls in the last year	0.1	0.1	0.3	-0.2	-0.2	0.0	-0.1	-0.3	-0.3	-0.4	-0.2	-0.4	-0.4	0.1	0.1	-0.4	-0.6
Medication: Lansoprazole	0.1	0.1	0.3	-0.3	-0.1	-0.6	-0.1	-0.2	-0.4	-0.2	-0.2	-0.0	-0.3	0.1	-0.1	-0.2	-0.2
Arm fat mass (right)	0.1	0.3	1.6	-0.2	-0.3	0.7	-0.4	0.1	0.4	0.2	-0.2	0.2	0.2	-0.7	-1.3	0.3	1.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.4	0.1	0.1	-0.3	0.0	0.2	0.3	0.3	0.2	0.1	0.3	-0.2	-0.2	0.3	0.6
Birth weight	0.1	0.2	1.2	0.1	0.1	0.1	0.1	-0.3	-0.4	-0.4	-0.2	-0.5	-0.3	0.6	0.4	-0.2	-1.1
High blood pressure (siblings)	0.1	0.1	0.3	0.4	0.3	0.6	0.3	0.4	0.5	0.5	0.2	0.5	0.4	0.1	-0.2	0.4	0.2
Worry too long after embarrassment	0.1	0.2	0.4	0.4	0.3	0.2	0.5	0.6	0.4	0.5	0.4	0.3	0.6	0.3	0.2	0.5	-0.3
Whole body fat mass	0.1	0.3	1.6	-0.2	-0.3	0.9	-0.4	0.0	0.4	0.2	-0.2	0.1	0.1	-0.8	-1.3	0.3	1.1
Leg fat mass (right)	0.1	0.4	1.3	0.3	0.2	1.1	0.1	0.5	0.9	0.6	0.2	0.7	0.5	-0.2	-0.7	0.7	0.6
Comparative height size at age 10	0.1	0.6	1.0	-0.5	-1.0	-0.2	-0.8	-0.7	-0.9	-0.8	-1.0	-1.0	-0.5	-1.0	-0.8	-0.7	0.7
Number of full sisters	0.1	0.1	0.5	0.6	0.1	0.7	0.2	0.4	0.1	0.3	0.1	0.4	0.4	-0.1	-0.5	0.5	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.3	-0.5	-0.3	-0.2	-0.4	-0.5	-0.6	-0.5	-0.4	-0.2	-0.6	0.1	-0.3	-0.5	-0.3
Average weekly red wine intake	0.1	0.1	0.4	-0.4	-0.0	-0.3	-0.1	-0.5	-0.2	-0.3	0.0	0.1	-0.4	0.5	0.5	-0.3	-0.7
Arm fat mass (left)	0.1	0.3	1.6	-0.3	-0.4	0.6	-0.5	-0.0	0.3	0.1	-0.3	0.1	-0.0	-0.8	-1.3	0.2	1.1
Miserableness	0.1	0.2	1.1	-0.1	0.1	-0.6	0.2	-0.3	-0.3	-0.4	-0.1	-0.2	-0.3	0.6	0.7	-0.3	-1.1
Guilty feelings	0.1	0.1	0.4	-0.2	-0.3	-0.5	-0.3	-0.1	-0.6	-0.1	-0.2	-0.2	-0.2	-0.3	-0.7	-0.1	0.6
Medication: Blood pressure	0.1	0.3	0.5	0.5	0.7	-0.1	0.6	0.6	0.7	0.5	0.5	0.6	0.5	0.5	0.3	0.5	-0.4
Cholesterol lowering medication	0.1	0.1	0.5	0.4	0.3	0.7	0.3	0.6	0.4	0.4	0.3	0.2	0.4	-0.1	-0.3	0.4	0.2
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.4	0.2	0.4	-0.0	0.4	0.5	0.5	0.5	0.4	0.4	0.6	0.2	0.0	0.6	0.1
Heart disease (siblings)	0.1	0.1	0.7	0.0	0.2	-0.2	0.2	0.0	-0.1	-0.0	0.2	0.0	-0.1	0.5	0.5	-0.2	-0.8
Leg fat mass (left)	0.1	0.4	1.6	0.3	0.2	1.3	0.1	0.6	0.9	0.7	0.3	0.7	0.5	-0.2	-0.9	0.8	0.7
Worry (Nagel 2018)	0.0	0.1	0.5	0.1	-0.1	-0.7	-0.1	-0.1	-0.3	-0.2	-0.1	-0.1	-0.3	0.1	-0.0	-0.1	0.1
Alzheimer’s Disease (in father)	0.0	0.0	0.2	0.0	0.3	-0.4	0.2	0.2	-0.0	0.2	-0.0	0.4	0.1	0.3	0.1	0.1	-0.2
Lupus	0.0	0.1	0.4	0.1	-0.1	0.7	-0.1	-0.0	-0.0	-0.2	0.0	-0.3	-0.2	-0.2	-0.3	-0.1	-0.0
Heel T-Score	0.0	0.2	0.9	0.7	0.3	1.0	0.3	0.3	-0.3	0.2	0.1	0.3	0.3	0.3	0.1	0.4	-0.4
Vitamin and mineral supplements	0.0	0.0	0.1	0.1	-0.1	-0.2	-0.1	0.0	0.3	-0.0	-0.3	-0.1	0.1	-0.2	-0.2	-0.1	0.3
Serious illness, injury or assault to yourself	0.0	0.0	0.1	-0.1	-0.1	0.2	-0.2	-0.2	0.1	-0.1	-0.0	0.2	-0.3	-0.0	-0.2	-0.2	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.3	0.3	0.0	0.5	0.0	0.2	0.1	0.3	0.0	0.3	0.3	-0.1	-0.6	0.3	0.5
Heart attack	0.0	0.1	0.2	0.0	0.2	-0.2	0.2	0.3	0.3	0.3	0.2	0.2	0.4	0.0	-0.0	0.4	0.2
Pain all over the body in last month	0.0	0.0	0.2	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.2	-0.1	0.4	0.5	0.1	-0.2
Hip circumference	0.0	0.2	0.8	-0.5	-0.4	0.3	-0.5	-0.1	-0.0	-0.1	-0.3	0.1	-0.1	-0.7	-0.9	0.1	0.9
Number of live births	0.0	0.0	0.1	0.1	0.1	0.4	0.1	-0.0	-0.1	0.0	0.2	0.3	0.1	0.2	0.2	0.1	-0.2
Lung cancer (father)	0.0	0.0	0.1	-0.3	-0.2	-0.2	-0.1	-0.0	0.1	-0.0	0.1	-0.1	-0.1	-0.1	-0.3	-0.1	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.0	0.1	0.2	0.1	0.3	0.2	0.3	-0.1	0.2	0.2	0.1	0.0	-0.2	-0.4	0.1	0.0
Headache pain in last month	0.0	0.0	0.1	0.1	0.1	0.3	0.1	-0.1	-0.1	-0.1	0.0	0.4	-0.2	0.3	0.1	-0.0	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.1	0.2	0.1	0.2	-0.3	0.1	0.2	-0.1	0.3	0.1	0.4	0.3	0.2	0.1	0.2	0.4
Loneliness, isolation	0.0	0.1	0.4	-0.2	-0.1	-0.6	-0.2	-0.2	-0.1	-0.2	-0.2	-0.2	-0.3	-0.1	-0.2	-0.1	-0.1
Medication for cholesterol	0.0	0.1	0.3	0.2	0.1	0.3	0.2	0.2	0.1	0.2	0.3	-0.0	0.2	0.3	0.5	0.2	-0.3
Fractured/broken bones in last 5 years	0.0	0.0	0.1	0.4	0.1	0.4	0.1	0.3	0.1	0.2	0.1	0.1	0.2	-0.1	0.2	0.1	0.3

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CD46

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Trait associations