TWAS
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Traits
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Pulse rate, automated reading
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chr1:236,170,665-237,625,236
Best TWAS P=5.15e-12 · Best GWAS P=2.81e-07 conditioned to 0.137
236.2M
236.4M
236.6M
236.8M
237M
237.2M
237.4M
237.6M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
ACTN2
0.14
0.08
blup
115
0.09
1.5e-09
-4.2
6.9
5.1e-12
-0.57
0.09
0.81
TRUE
1
GTEx
Esophagus Muscularis
ACTN2
0.25
0.08
enet
23
0.14
4.4e-09
-4.3
5.9
3.2e-09
-0.75
0.01
0.98
FALSE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ACTN2
0.05
0.02
blup
115
0.03
3.3e-04
-2.7
5.3
1.1e-07
-0.53
0.03
0.05
FALSE