TWAS hub - TEKT3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1790	0.0320	2.2e-12	0.210	0.118	0.178	NA	0.205	5.2e-25	3.7e-14	3.4e-21	NA	2.0e-24
2	METSIM	Adipose	0.1547	0.0290	1.4e-14	0.163	0.108	0.156	0.028	0.009	1.1e-23	7.1e-16	1.4e-22	3.8e-05	1.6e-02
3	ROSMAP	Brain Pre-frontal Cortex	0.1537	0.0347	7.4e-08	0.032	0.060	0.060	0.061	0.035	4.7e-05	3.7e-08	3.8e-08	2.3e-08	2.4e-05
4	TCGA	Breast Invasive Carcinoma	0.0226	0.0132	3.6e-03	0.005	0.009	0.003	NA	0.008	2.9e-02	3.8e-03	5.7e-02	NA	8.8e-03
5	TCGA	Glioblastoma Multiforme	0.1930	0.0910	4.8e-03	0.008	0.075	0.061	NA	0.004	1.8e-01	2.7e-03	6.3e-03	NA	2.3e-01
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0463	0.0259	3.3e-03	0.002	0.010	0.002	NA	0.006	1.7e-01	2.4e-02	2.0e-01	NA	5.7e-02
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0666	0.0245	2.4e-07	0.082	0.068	0.070	NA	0.076	1.6e-09	3.7e-08	2.5e-08	NA	6.2e-09
8	TCGA	Brain Lower Grade Glioma	0.0772	0.0282	1.5e-07	0.084	0.078	0.079	NA	0.082	7.9e-10	3.2e-09	3.0e-09	NA	1.5e-09
9	TCGA	Pancreatic Adenocarcinoma	0.3600	0.1120	2.4e-09	0.299	0.112	0.203	NA	0.013	4.8e-13	2.1e-05	6.3e-09	NA	9.1e-02
10	TCGA	Stomach Adenocarcinoma	0.0480	0.0270	9.8e-03	0.027	0.023	0.016	NA	0.018	4.7e-03	8.2e-03	2.3e-02	NA	1.6e-02
11	TCGA	Thyroid Carcinoma	0.0590	0.0270	3.8e-04	0.063	0.036	0.049	NA	0.048	9.5e-07	1.7e-04	1.5e-05	NA	1.7e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Pulse rate, automated reading	4.6	14.9	56.4	6.0	1.7	7.5	3.1	1.7	4.0	2.5	2.4	2.9	3.6	2.3
Tinnitus: Yes, but not now, but have in the past	4.3	4.6	6.5	1.5	2.0	2.5	1.8	2.6	0.7	2.4	2.5	2.2	2.0	2.6
Stomach or abdominal pain in last month	4.1	5.0	11.9	0.2	-2.0	-1.6	-3.5	-1.5	-3.3	-2.2	-2.0	-1.8	-2.4	-2.4
Leg pain on walking	3.1	3.9	7.5	-0.6	2.4	0.4	1.7	2.7	0.1	2.3	2.5	2.1	1.7	2.7
Reaction Time	3.0	5.7	8.4	1.2	2.6	2.3	2.0	2.6	1.6	2.8	2.9	2.9	1.9	2.9
Depression (self-reported)	3.0	3.6	6.0	0.7	-2.2	-0.5	-2.0	-1.9	-1.4	-2.2	-2.2	-2.3	-1.9	-2.4
Handedness (chirality/laterality): Left-handed	3.0	3.6	5.7	0.4	2.3	1.4	1.4	2.4	1.1	2.4	2.3	2.3	1.5	2.3
HbA1C	2.9	3.2	5.4	0.9	2.0	1.7	2.1	1.1	1.9	2.0	2.1	1.9	1.0	2.3
Pulse rate	2.9	5.0	23.3	4.8	-0.5	4.8	1.0	-0.3	2.5	0.0	-0.1	0.1	0.7	0.4
Had major operations	2.7	3.1	5.0	1.0	-2.0	0.3	-1.5	-2.2	-0.6	-2.1	-2.2	-2.0	-1.9	-2.1
Commuting to job workplace: Public transport	2.6	3.0	4.6	-0.4	2.1	1.2	2.0	2.1	-0.1	2.0	2.2	1.7	2.1	1.7
Type 2 Diabetes (T2D) (2012)	2.4	2.8	5.1	1.0	1.6	2.0	1.6	1.6	1.7	1.7	1.8	1.6	1.2	2.2
Health satisfaction	2.4	3.1	6.6	2.0	1.4	2.6	1.1	2.3	0.7	1.6	1.8	1.5	0.9	2.3
Worrier / anxious feelings	2.3	4.4	7.4	1.2	1.9	2.7	2.2	1.9	2.1	2.3	2.3	2.2	1.4	2.5
Chronic bronchitis/emphysema (mother)	2.3	2.7	5.7	-0.2	2.0	1.0	1.0	2.4	0.1	1.9	2.1	2.1	1.4	1.8
Alzheimer’s Disease (in father)	2.2	2.4	3.9	1.4	1.7	1.7	1.3	1.5	0.3	1.6	2.0	1.8	1.1	1.8
Medication: Ventolin 100micrograms inhaler	2.2	2.8	4.5	-0.5	2.0	0.5	2.1	2.0	0.8	2.0	1.9	1.6	1.4	2.1
Coronary Artery Disease (CAD)	2.1	2.5	4.8	2.2	1.4	2.2	1.3	1.4	0.9	1.5	1.6	1.8	1.4	1.4
Average weekly spirits intake	2.1	2.6	3.7	-1.9	-1.6	-1.9	-1.3	-1.7	-0.5	-1.9	-1.6	-1.7	-1.9	-1.0
Average weekly champagne plus white wine intake	2.1	2.9	5.5	0.1	2.1	0.7	1.6	1.4	0.8	2.3	2.2	2.3	2.0	1.7
Multivitamins +/- minerals	2.0	2.6	4.7	0.1	1.9	1.7	1.0	1.5	-0.2	2.0	2.2	1.8	1.9	1.8
Lupus	1.9	2.9	6.4	-0.2	-2.1	-0.7	-0.9	-1.0	-2.0	-2.2	-2.2	-2.5	-1.3	-1.9
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.2	3.2	-1.5	1.8	-0.3	1.7	1.7	1.3	1.5	1.5	1.4	1.3	1.7
Hypothyroidism/myxoedema (self-reported)	1.9	3.6	12.1	-0.3	-2.1	-1.4	-2.5	-0.7	-3.5	-1.6	-1.5	-2.2	-1.3	-1.9
Wears glasses or contact lenses	1.9	2.2	3.8	-0.7	1.6	1.0	1.7	1.9	1.4	1.6	1.5	1.3	1.1	2.0
Ever had prostate specific antigen (PSA) test	1.9	2.2	4.4	0.0	1.5	0.2	2.1	1.6	1.4	1.8	1.5	1.5	1.7	1.6
Ever had bowel cancer screening	1.8	2.1	4.2	-0.3	-1.6	-1.4	-0.9	-1.7	-0.7	-1.6	-1.8	-2.1	-1.7	-1.2
Hypothyroidism (self reported)	1.7	4.0	11.4	0.7	-2.4	-0.6	-2.6	-1.0	-3.4	-1.8	-1.8	-2.5	-1.5	-2.0
Angina	1.7	2.3	3.9	0.0	-1.8	-0.9	-2.0	-1.9	-0.1	-1.6	-1.8	-1.4	-1.9	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.3	12.6	-1.4	-2.1	-3.0	-3.0	-1.3	-3.5	-2.2	-1.9	-2.0	-1.8	-2.1
Length of working week for main job	1.7	1.9	3.2	0.9	1.5	1.4	1.4	1.7	0.8	1.4	1.5	1.3	1.0	1.8
Leg fat percentage (left)	1.7	6.2	9.8	0.1	2.7	2.1	3.0	1.9	3.0	2.7	2.5	2.7	3.1	2.1
Leg fat percentage (right)	1.6	5.7	9.1	0.1	2.6	1.9	3.0	1.8	2.9	2.6	2.3	2.6	3.0	2.1
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	9.0	3.0	-0.9	1.9	-0.5	-1.1	-0.4	-1.0	-1.2	-1.3	-0.7	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.4	5.4	0.0	-2.1	-2.3	-1.6	-2.1	-1.6	-2.1	-2.1	-1.8	-1.4	-2.0
Medication for hormone replacement therapy	1.5	1.7	2.8	-1.1	-1.6	-1.3	-0.8	-1.3	-0.8	-1.3	-1.6	-1.6	-0.8	-1.7
Medication: Levothyroxine sodium	1.5	2.6	7.8	-0.2	-1.8	-0.9	-2.1	-0.9	-2.8	-1.4	-1.3	-1.7	-1.4	-1.6
Knee pain experienced in last month	1.5	2.4	6.8	-0.2	1.8	0.7	2.0	0.5	2.6	1.6	1.4	1.7	1.1	1.7
Trunk fat percentage	1.4	5.5	10.0	-0.0	2.6	2.2	2.6	2.3	1.7	2.7	2.5	2.5	3.2	1.9
Hair/balding pattern: Pattern 3	1.4	2.2	3.6	0.2	-1.9	-0.3	-1.5	-1.9	-0.7	-1.7	-1.7	-1.8	-1.5	-1.6
Forced vital capacity (FVC), Best measure	1.4	5.2	12.7	-1.3	-1.9	-3.2	-2.9	-1.1	-3.6	-2.2	-1.8	-2.1	-1.8	-1.9
Body fat percentage	1.4	5.4	9.6	0.3	2.5	2.3	2.8	2.1	2.1	2.6	2.4	2.5	3.1	1.9
Commuting to job workplace: Cycle	1.4	1.7	3.0	-0.0	-1.6	-0.0	-1.3	-1.7	-0.9	-1.7	-1.4	-1.5	-1.5	-1.3
Leg fat mass (left)	1.4	5.4	9.9	-0.2	2.6	1.8	2.9	2.0	2.2	2.7	2.4	2.5	3.1	1.9
Schizophrenia vs Biploar Disorder	1.3	1.7	3.2	1.0	-1.6	-0.7	-1.2	-1.2	-0.5	-1.6	-1.5	-1.5	-1.8	-1.2
BMI	1.3	7.8	10.4	1.0	2.9	3.1	3.1	2.5	2.2	3.2	3.1	3.1	2.9	2.8
Lung FVC	1.3	6.5	10.8	-0.3	-2.5	-2.7	-2.9	-2.3	-3.3	-2.8	-2.5	-2.7	-2.4	-2.4
Taking other prescription medications	1.3	2.0	5.3	2.3	-1.6	0.7	-0.7	-1.6	-0.4	-1.5	-1.4	-1.6	-1.7	-1.0
Illnesses of siblings	1.3	1.8	5.0	0.8	1.2	2.2	0.4	1.4	-1.1	1.6	1.6	1.5	0.7	1.3
Mean time to correctly identify matches	1.3	2.6	4.7	0.7	1.9	1.0	1.2	1.7	1.0	1.9	2.0	2.0	1.3	2.2
Eye problems/disorders: Glaucoma	1.3	1.6	2.4	-0.5	-1.4	-1.1	-1.5	-1.0	-1.1	-1.4	-1.4	-1.3	-1.1	-1.6
Unable to work because of sickness or disability	1.3	1.6	3.9	2.0	0.9	1.4	1.1	1.0	1.8	1.0	1.0	0.9	1.5	0.5
Medication: Co-codamol	1.2	1.4	2.4	-1.4	1.2	-0.1	1.5	1.1	0.8	1.2	1.2	1.1	1.3	1.4
Medication: Ramipril	1.2	1.5	4.2	1.8	0.5	2.0	1.2	0.4	1.7	0.9	0.8	0.9	1.1	0.7
Medication: Simvastatin	1.2	1.8	4.2	0.2	1.4	0.6	1.5	1.1	2.0	1.5	1.4	1.4	0.9	1.6
Exposure to tobacco smoke at home	1.2	1.4	2.1	1.4	-1.2	1.1	-0.9	-1.2	-0.9	-1.1	-1.2	-1.2	-1.4	-1.0
Ever highly irritable/argumentative for 2 days	1.2	1.5	2.8	0.6	1.4	1.7	0.6	1.3	0.2	1.3	1.5	1.5	1.2	1.2
Angina (self-reported)	1.2	1.5	2.5	0.3	-1.5	-0.6	-1.5	-1.6	0.2	-1.3	-1.4	-1.2	-1.6	-1.2
Leg fat mass (right)	1.2	4.5	8.3	-0.3	2.4	1.6	2.7	1.7	2.1	2.4	2.1	2.3	2.9	1.7
Qualifications: nursing, teaching	1.2	1.8	2.8	-1.4	1.5	-0.5	1.2	1.5	0.5	1.6	1.6	1.7	1.4	1.4
Pain type(s) experienced in last month: Hip pain	1.2	1.5	10.1	-0.1	0.5	-0.4	1.7	-1.2	3.2	0.5	-0.1	0.3	0.9	-0.2
Verbal and Numeric Reasoning (VNR)	1.1	2.6	4.7	-0.7	-1.7	-1.4	-1.6	-1.0	-2.2	-2.0	-1.8	-2.0	-1.4	-1.6
Medication: Atenolol	1.1	1.4	2.8	0.7	-1.4	-0.0	-0.9	-1.4	0.2	-1.4	-1.5	-1.4	-1.7	-1.0
Forced vital capacity (FVC)	1.1	4.2	12.0	-0.6	-1.8	-2.4	-2.5	-1.3	-3.5	-1.9	-1.6	-1.9	-1.6	-1.9
Financial difficulties in last 2 years	1.1	1.4	5.3	1.7	-1.1	1.0	-1.2	-0.2	-2.3	-1.1	-0.6	-0.8	-0.9	-0.8
Forced expiratory volume in 1-second (FEV1)	1.1	3.6	10.0	-0.5	-1.8	-1.9	-2.6	-1.3	-3.2	-1.8	-1.6	-1.6	-1.6	-1.8
Arm fat percentage (left)	1.1	4.5	7.2	0.5	2.3	2.4	2.5	1.7	1.8	2.4	2.2	2.2	2.7	1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.7	-0.2	-0.9	-1.2	-0.7	-1.6	0.9	-1.4	-1.3	-1.2	-1.4	-0.8
Financial situation satisfaction	1.1	1.4	6.4	2.1	0.5	2.5	0.8	0.7	0.5	0.4	0.8	0.8	0.9	0.6
Major Depression (MDD)	1.0	1.2	3.7	1.9	0.6	1.8	-0.2	1.3	-1.5	0.9	0.9	0.6	0.8	0.1
LDL Cholesterol	1.0	1.5	2.8	0.5	1.2	0.8	1.7	1.3	1.0	1.5	1.3	1.2	1.5	1.4
Diabetes (mother)	1.0	1.3	3.2	1.2	0.7	1.8	1.2	0.7	0.9	1.2	1.1	1.1	1.2	0.7
Townsend deprivation index at recruitment	1.0	1.4	2.5	1.6	0.9	1.1	1.6	1.1	1.5	0.9	1.0	0.8	0.9	1.3
High blood pressure (mother)	1.0	1.3	6.7	2.2	0.5	2.6	0.5	0.6	0.5	0.8	0.7	0.7	0.3	0.9
Trunk fat mass	1.0	4.2	8.9	-0.3	2.3	1.9	2.4	2.0	1.3	2.3	2.1	2.1	3.0	1.5
Heart attack	1.0	1.3	2.3	-1.2	1.2	-0.5	0.9	1.0	1.2	1.1	1.2	1.5	1.4	0.9
Arm fat percentage (right)	1.0	3.9	6.4	0.8	2.1	2.4	2.2	1.6	1.5	2.2	2.1	2.1	2.5	1.6
Whole body fat mass	1.0	4.2	8.7	-0.0	2.3	1.9	2.5	1.8	1.6	2.3	2.1	2.1	2.9	1.5
Number of full sisters	1.0	1.3	7.1	1.4	0.2	1.1	1.2	0.6	2.7	0.5	0.5	0.4	0.6	0.8
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.0	7.3	-1.8	-0.8	-2.7	-1.5	-1.1	-1.3	-1.1	-1.1	-1.1	-0.8	-1.4
Diabetes diagnosed by doctor	1.0	1.7	2.7	0.3	1.5	1.1	1.0	1.7	0.4	1.6	1.6	1.3	1.6	1.3
Arm fat mass (left)	1.0	3.9	6.9	0.1	2.2	2.0	2.5	1.6	1.6	2.3	2.1	2.0	2.6	1.6
Number of self-reported non-cancer illnesses	1.0	1.7	2.4	1.4	-1.5	0.3	-1.3	-1.0	-1.2	-1.5	-1.5	-1.4	-1.4	-1.4
Body Mass Index (BMI) (2010)	0.9	1.3	3.6	0.9	0.5	1.6	1.7	0.5	1.1	1.2	0.7	0.8	1.9	0.2
Fasting Glucose	0.9	1.0	1.8	0.5	1.3	0.8	1.0	0.7	1.2	1.1	1.1	1.1	1.0	1.1
Body mass index (BMI)	0.9	4.0	6.9	0.5	2.0	2.0	2.6	1.3	2.4	2.2	2.0	2.1	2.3	1.8
Had other major operations	0.9	1.1	2.8	-1.1	-0.7	-1.7	-1.2	-0.6	-1.7	-0.9	-0.6	-0.7	-1.0	-0.6
Hip circumference	0.9	3.9	6.6	1.1	1.9	2.2	2.6	1.4	2.1	2.1	1.9	1.9	2.5	1.7
Medication: Cholesterol lowering	0.9	1.4	4.7	1.6	0.7	1.6	1.1	0.4	2.2	0.9	0.8	0.9	0.8	0.8
Glaucoma (self-reported)	0.9	1.0	1.7	0.2	-1.3	-0.9	-1.1	-1.0	-0.7	-1.1	-1.3	-1.1	-0.8	-1.3
Pulse wave peak to peak time	0.9	1.0	1.7	-1.2	-0.9	-0.6	-1.0	-0.8	-1.3	-1.1	-1.1	-1.1	-0.6	-1.1
Neck or shoulder pain in last month	0.9	1.3	4.0	0.1	1.2	0.3	1.2	0.9	2.0	1.0	1.1	1.1	0.5	1.7
Ever taken oral contraceptive pill	0.9	1.0	2.2	-1.1	0.9	0.1	1.0	1.4	-0.6	1.3	1.1	0.8	1.5	0.7
Pack years of smoking	0.9	1.3	2.5	-0.5	-1.1	-1.6	-1.0	-0.9	-1.0	-1.3	-1.2	-1.3	-0.8	-1.5
Intelligence (Savage-Jansen 2018)	0.8	2.4	4.2	1.1	-2.0	0.0	-1.4	-1.0	-1.5	-2.0	-1.9	-2.0	-1.5	-1.3
Alzheimer’s Disease (in mother)	0.8	0.9	1.7	1.1	-1.3	-1.1	-0.1	-1.3	-0.1	-0.8	-1.0	-1.0	-1.1	-1.0
Blood White Count	0.8	6.1	9.2	0.5	2.8	1.7	2.6	2.5	2.5	2.9	2.7	3.0	2.4	2.5
Medication: Metformin	0.8	1.2	2.4	-0.2	1.2	0.9	1.5	0.6	1.1	1.3	1.1	0.8	1.4	1.0
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.9	-0.7	1.0	-0.1	0.7	1.7	-0.6	1.0	1.1	1.0	1.3	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	3.0	-0.2	-1.7	-0.8	-1.2	-1.2	-0.9	-1.5	-1.7	-1.7	-1.1	-1.7
Chronic bronchitis/emphysema (father)	0.8	0.9	1.8	-0.1	1.4	-0.1	0.9	1.0	0.7	1.1	1.1	1.1	1.2	1.1
Falls in the last year	0.8	1.0	1.6	-0.2	1.2	0.2	1.3	1.2	0.7	1.3	1.1	1.0	1.2	0.9
Prospective memory result	0.8	1.0	6.5	2.6	-0.5	1.0	-0.6	-1.3	0.6	-0.6	-0.6	-0.2	-0.2	-0.8
Arm fat mass (right)	0.8	3.3	6.2	0.2	2.0	1.8	2.1	1.6	1.2	2.1	1.9	1.9	2.5	1.4
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	3.6	-0.8	-1.0	-0.9	-1.5	-0.9	-1.3	-1.1	-1.1	-1.0	-1.9	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.0	1.1	0.8	1.4	0.7	0.5	1.2	1.0	0.9	0.8	0.7	1.0
Commuting to job workplace: Walk	0.8	0.9	2.2	-0.6	1.0	0.3	1.5	0.0	1.1	0.8	0.8	0.7	1.1	1.2
Medication: Gliclazide	0.8	0.9	2.7	-1.6	0.7	-1.3	-0.3	0.8	-1.3	0.8	0.8	0.6	0.1	0.8
Tinnitus: Yes, now most or all of the time	0.8	0.9	4.1	-0.2	-0.7	-0.4	-0.3	-1.5	2.0	-0.8	-0.9	-0.4	-0.8	-0.7
Medication: Bendroflumethiazide	0.8	1.2	3.3	0.1	1.2	0.8	1.2	0.9	1.5	1.1	1.0	1.1	0.4	1.8
Depressed Affect (Nagel 2018)	0.7	1.4	2.9	0.2	-1.3	0.1	-1.7	-1.1	-0.6	-1.6	-1.2	-1.3	-1.6	-0.9
Maternal smoking around birth	0.7	1.0	5.8	0.3	0.8	0.7	0.8	0.2	2.4	0.9	0.6	0.8	0.2	0.9
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.5	1.3	0.9	1.6	-0.4	1.0	-0.5	0.6	0.5	0.1	-0.3	1.3
Mouth/teeth dental problems: Dentures	0.7	1.2	4.0	1.2	-1.0	-0.2	-1.2	-0.7	-1.1	-1.1	-1.1	-1.2	-2.0	-0.4
Illnesses of mother	0.7	0.9	3.4	-0.3	-0.8	-0.6	-1.2	-0.6	-1.9	-1.0	-0.8	-0.9	-0.6	-1.1
Tense / ‘highly strung’	0.7	1.2	4.6	0.9	0.8	1.4	0.8	0.4	2.1	0.9	0.8	1.1	0.2	1.4
Pulse wave reflection index	0.7	0.9	3.5	-1.7	0.8	-1.9	-0.1	0.4	0.2	0.8	0.9	0.8	-0.2	0.9
Eye problems/disorders: None of the above	0.7	0.8	2.8	1.7	0.4	1.5	1.0	0.5	-0.2	0.8	0.8	0.6	0.9	0.7
Age at last live birth	0.7	1.0	2.8	1.6	-1.1	0.9	-1.7	-0.2	-1.3	-0.6	-0.3	-0.2	-0.4	-1.1
Back pain experienced in last month	0.7	1.0	2.8	-0.5	1.2	0.4	0.7	0.5	1.7	1.1	0.9	1.3	0.3	1.2
Medication: Aspirin	0.7	0.9	1.3	-0.1	-1.0	-1.0	-1.2	-0.9	-0.6	-1.1	-1.1	-1.1	-0.8	-1.0
Miserableness	0.7	1.1	2.5	0.5	-1.2	0.5	-1.4	-0.8	-1.1	-1.3	-1.1	-0.9	-0.7	-1.6
Irritability	0.7	1.1	7.0	2.7	-0.2	1.8	-0.6	-0.5	-0.2	-0.1	-0.2	0.0	-1.2	0.2
Diastolic blood pressure, automated reading	0.7	2.0	11.1	3.3	-0.6	3.1	0.0	-0.3	0.5	-0.2	-0.5	-0.4	0.3	-0.6
Heart attack/myocardial infarction (self-reported)	0.7	1.0	1.7	-1.3	1.0	-0.7	0.8	0.8	0.9	0.9	1.0	1.3	1.1	0.7
Alzheimer’s Disease (including proxy)	0.6	0.9	5.2	2.3	0.4	1.2	0.8	-0.0	0.3	0.8	0.9	0.7	-0.2	0.7
HDL Cholesterol	0.6	1.0	2.4	-0.2	1.0	0.5	1.5	-0.2	1.5	1.1	0.9	1.1	1.1	0.6
Primary Biliary Cirrhosis	0.6	0.8	3.8	1.9	0.5	1.3	-0.2	0.6	0.6	0.5	0.6	0.7	-0.5	1.1
Cardiovascular Disease	0.6	2.1	5.6	2.2	0.9	2.4	1.2	0.7	2.0	1.2	1.0	1.1	0.8	1.3
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	1.4	0.6	-0.9	-0.4	-0.9	-0.4	-1.0	-1.0	-1.0	-0.9	-0.5	-1.2
Diabetes (self-reported)	0.6	1.0	1.7	0.4	1.2	0.8	0.9	1.2	0.3	1.2	1.1	0.9	1.3	0.9
Time employed in main current job	0.6	0.6	3.4	1.8	0.1	1.8	0.2	0.1	-0.1	0.4	0.2	0.2	0.4	0.2
Asthma	0.6	1.2	3.3	-1.1	1.0	-0.4	1.1	1.5	1.3	1.0	1.1	0.9	0.2	1.8
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.3	0.4	1.0	0.4	0.9	0.9	0.9	1.1	1.1	1.0	0.7	1.1
Medication: Lansoprazole	0.6	0.7	1.2	0.3	1.0	0.6	0.7	1.0	0.6	1.1	1.1	1.0	0.6	0.9
Lung cancer (father)	0.6	0.7	2.8	-1.7	0.0	-1.1	-0.9	0.2	-1.7	-0.2	-0.0	-0.1	0.0	-0.5
Medication: Seretide 50 evohaler	0.6	0.7	3.3	-1.8	-0.4	-1.1	-0.9	-0.6	-0.7	-0.5	-0.6	-0.3	-0.4	-0.5
Commuting to job workplace: Car/motor vehicle	0.6	0.7	3.1	1.8	-1.0	0.5	-0.7	-0.2	-0.2	-0.6	-0.9	-0.8	-0.9	-0.7
Medication: Aspirin	0.6	0.8	1.3	0.3	-1.1	-0.7	-1.1	-0.9	-0.4	-1.1	-1.1	-1.1	-0.8	-0.9
Supplements: Vitamin C	0.6	0.7	2.1	0.2	-0.7	-0.3	-0.7	-0.4	-1.4	-0.6	-0.8	-1.2	-1.5	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.2	0.6	0.6	0.3	0.6	1.2	-0.3	0.9	1.0	0.5	0.1	1.5
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.8	1.7	-1.0	0.7	0.3	-0.8	1.4	-0.5	-0.8	-0.8	-1.1	-0.1
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.4	1.0	-1.0	1.0	0.3	-1.2	0.3	-1.1	-1.0	-1.1	-0.4	-0.7
Age started oral contraceptive pill	0.6	0.7	1.7	-0.8	0.8	-0.1	1.3	0.4	1.1	0.9	0.8	0.6	0.9	1.0
Ever depressed for a whole week	0.6	0.7	1.7	-0.5	1.0	0.5	0.6	1.3	0.5	0.8	0.9	1.0	1.0	0.7
Basal cell carcinoma (self-reported)	0.6	0.7	2.1	-0.3	1.1	0.1	0.7	0.8	1.1	0.8	0.8	0.6	0.3	1.5
Schizophrenia (2018)	0.5	1.0	3.6	0.8	-1.0	0.3	-1.1	-1.4	0.7	-0.7	-1.0	-0.7	-1.9	-0.5
Bipolar Disorder (2011)	0.5	0.5	2.2	-0.6	-0.2	-0.0	-1.2	-0.0	-1.5	-0.5	-0.2	-0.3	0.1	-0.8
Ever had hysterectomy (womb removed)	0.5	0.5	1.9	-1.4	0.2	-1.3	0.3	0.9	-0.7	0.1	0.1	-0.4	-0.2	0.6
Relative age voice broke	0.5	0.7	4.9	0.8	-0.5	-0.3	-1.0	0.5	-2.2	-0.3	0.0	-0.5	-0.6	0.2
Serious illness, injury or assault to yourself	0.5	0.6	2.1	1.5	-0.8	0.8	-0.5	-0.4	0.2	-0.6	-0.6	-0.8	-1.1	0.0
Waist circumference	0.5	2.0	4.6	0.3	1.4	1.5	1.7	1.2	1.0	1.5	1.4	1.5	2.1	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.0	0.8	0.8	1.4	0.6	0.9	0.3	0.9	1.1	1.1	0.7	0.8
Hair/balding pattern: Pattern 2	0.5	0.7	4.3	-2.1	0.2	-1.6	-0.2	0.3	-0.1	-0.1	-0.0	-0.1	-0.3	0.2
Mouth/teeth dental problems	0.5	0.8	3.1	-1.8	0.9	-1.0	0.2	0.6	0.5	0.6	0.6	0.8	1.4	-0.0
Pain all over the body in last month	0.5	0.5	1.3	-0.2	0.8	-0.0	0.1	1.1	0.6	0.7	0.9	0.8	0.4	1.1
Fluid intelligence score	0.5	1.1	2.8	-0.3	-1.2	-0.4	-1.0	-0.7	-1.7	-1.3	-1.2	-1.3	-0.7	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.1	0.9	0.8	1.5	0.4	1.3	1.1	0.7	0.6	0.7	-0.0	0.9
Happiness	0.5	0.6	1.8	0.5	0.6	1.3	-0.5	1.0	-1.4	0.3	0.6	0.5	0.5	0.1
Pulse wave Arterial Stiffness index	0.5	0.6	0.9	0.9	0.8	0.4	0.6	0.7	0.8	0.9	0.9	0.9	0.5	0.9
Comparative body size at age 10	0.5	1.3	3.2	-0.3	1.3	0.3	1.4	0.4	1.5	1.2	1.1	1.5	1.8	0.7
Shortness of breath walking on level ground	0.5	0.6	1.6	1.2	-0.9	0.8	-1.0	0.1	0.2	-0.6	-0.5	-0.4	-1.3	0.1
Medication: Blood pressure	0.5	0.9	4.8	2.2	-0.9	1.0	-0.2	-0.9	-0.2	-0.7	-0.7	-0.5	-0.3	-0.8
Migraine (self-reported)	0.5	0.6	3.3	-1.5	-0.2	-1.8	-0.7	-0.0	-0.1	-0.5	-0.2	-0.4	-0.6	0.3
Overall health rating	0.5	1.1	3.2	1.8	0.7	1.7	0.6	1.6	0.1	0.7	0.8	0.5	1.2	0.6
Illnesses of siblings: Diabetes	0.5	0.6	1.4	-0.4	-0.7	-0.4	-0.4	-0.8	0.4	-1.0	-0.9	-1.2	-0.6	-0.9
High cholesterol (Self-reported)	0.5	0.9	4.7	1.0	0.3	1.3	1.1	0.1	2.2	0.4	0.4	0.5	0.6	0.6
Medication: Lisinopril	0.5	0.7	2.9	-0.9	-0.4	-1.7	-0.9	-0.4	-1.2	-0.5	-0.5	-0.4	-0.1	-0.9
Risk taking	0.5	0.7	1.3	0.9	0.9	1.2	0.8	0.4	1.0	0.7	0.8	0.7	0.4	1.0
Bipolar Disorder or Schizophrenia	0.4	0.9	3.3	0.5	-0.9	0.4	-1.6	-1.3	0.2	-0.6	-0.8	-0.3	-1.8	-0.6
Blood Red Count	0.4	3.4	6.1	0.3	2.0	1.1	1.0	2.5	0.9	2.3	2.3	2.4	1.8	2.3
Allergy or Eczema	0.4	1.1	1.8	-0.8	1.1	0.6	0.7	1.3	-0.7	1.2	1.4	1.1	1.3	1.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.0	-0.2	0.9	-0.9	-0.3	0.9	-0.6	0.4	0.6	0.5	1.0	-0.0
Current tobacco smoking	0.4	0.6	2.0	0.6	0.9	0.4	0.5	1.4	0.6	0.8	0.9	0.7	0.1	1.1
Fed-up feelings	0.4	0.6	1.7	1.2	-0.8	1.3	-0.9	-0.7	-0.0	-0.9	-0.7	-0.4	-0.6	-0.6
Had menopause	0.4	0.5	2.3	0.0	0.1	0.5	1.5	-0.5	1.1	0.4	0.2	0.1	1.2	0.3
Qualifications: None of the above	0.4	0.8	3.9	-0.5	-0.5	-1.0	-0.0	-1.2	2.0	-0.8	-0.7	-0.6	-0.5	-0.3
Weight	0.4	1.8	4.6	-0.3	1.5	1.2	1.7	1.1	0.8	1.5	1.4	1.3	2.1	0.8
Medication: Paracetamol	0.4	0.7	1.9	-0.7	0.9	-0.6	0.3	0.5	1.4	0.8	0.8	1.4	0.5	0.9
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	3.8	-1.9	0.6	-1.1	-0.3	0.6	-0.7	0.4	0.4	0.3	0.0	0.5
High blood pressure (siblings)	0.4	0.5	2.8	-0.2	0.2	-1.7	0.6	-0.2	1.5	-0.2	-0.3	-0.1	0.4	-0.2
Number of full brothers	0.4	0.5	1.0	-0.9	0.5	-0.0	0.8	1.0	0.5	0.6	0.8	0.5	0.3	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.3	1.1	0.8	0.5	-0.2	1.1	-1.0	0.6	0.7	0.7	0.6	0.4
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.8	0.8	0.6	1.3	0.1	0.8	-0.5	0.7	0.7	0.7	0.4	0.4
Hypertension (Self-reported)	0.4	1.0	3.7	1.9	-0.6	1.9	-0.4	-0.9	0.8	-0.6	-0.7	-0.5	-0.7	-0.3
Illnesses of father: Heart disease	0.4	0.5	1.4	0.5	-0.9	-0.7	-0.3	-0.8	0.5	-0.6	-0.8	-0.8	-1.2	-0.1
Smoking status: Current	0.4	0.6	1.6	0.8	0.9	0.5	0.5	1.3	0.7	0.8	0.8	0.7	0.2	0.9
Mother’s age at death	0.4	0.5	1.9	-1.4	0.4	-1.3	0.4	0.1	0.8	0.2	0.2	0.3	0.4	0.2
Medication: Blood pressure	0.4	0.7	3.0	-0.8	1.0	0.4	0.9	-0.0	1.7	0.7	0.5	0.7	0.1	0.9
Medication: Atorvastatin	0.4	0.6	2.0	1.1	0.1	1.4	0.4	-0.3	1.4	0.0	-0.1	0.1	0.7	-0.2
Alcohol drinker status: Never	0.4	0.5	2.2	0.2	0.5	0.4	0.8	1.1	0.6	0.6	0.6	0.2	-0.5	1.5
Number of operations (self-reported)	0.4	0.6	1.2	0.5	-0.8	-0.3	-0.6	-0.7	-0.4	-1.0	-0.9	-0.9	-1.1	-0.5
Fractured/broken bones in last 5 years	0.4	0.5	1.1	-1.1	0.7	-0.2	0.7	0.0	0.4	0.7	0.7	0.9	0.7	0.7
Depression (Nagel 2018)	0.3	0.4	2.1	0.5	-0.2	0.1	-1.4	0.2	-0.8	-0.5	-0.2	-0.2	-1.2	0.1
Mean Putamen Volume	0.3	0.3	1.1	0.6	0.5	1.1	0.4	0.6	0.6	0.4	0.3	0.3	0.8	0.0
Rheumatoid Arthritis	0.3	0.4	3.1	-1.8	0.0	-0.5	0.6	0.0	-0.4	0.2	0.4	0.4	0.1	-0.0
Triglycerides	0.3	0.5	3.0	1.7	-0.2	0.4	-0.9	0.2	-1.1	-0.4	-0.1	-0.2	-0.5	0.0
Respiratory disease	0.3	0.6	1.6	-0.1	0.8	-0.2	0.6	1.3	0.8	0.7	0.8	0.8	0.1	1.2
Type 2 Diabetes (T2D) (2018)	0.3	0.5	0.9	0.5	0.7	0.7	0.1	0.9	-0.2	1.0	0.9	0.7	0.9	0.6
Number of treatments/medications taken	0.3	0.6	2.4	1.6	-0.7	1.4	0.1	-0.6	0.5	-0.5	-0.5	-0.5	-0.5	-0.3
Sensitivity / hurt feelings	0.3	0.6	1.8	0.0	0.8	1.4	0.6	0.2	0.5	0.8	0.8	0.8	-0.0	1.1
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.8	0.3	0.7	0.8	0.1	0.9	-0.3	0.5	0.8	0.8	0.5	0.4
Hearing difficulty/problems: Yes	0.3	0.5	1.2	0.7	-0.6	0.3	-0.4	-1.1	1.0	-0.4	-0.6	-0.2	-1.0	-0.3
Vitamin and mineral supplements	0.3	0.4	1.0	-0.3	-0.7	-0.9	-0.1	-0.2	1.0	-0.7	-0.7	-0.4	-0.4	-0.5
Supplements: Zinc	0.3	0.3	0.6	0.2	-0.5	-0.5	-0.5	-0.3	-0.8	-0.6	-0.5	-0.7	-0.7	-0.4
Severe depression (siblings)	0.3	0.3	1.2	0.3	0.3	0.8	0.5	0.5	1.1	0.5	0.3	0.4	0.8	0.1
Age when periods started (menarche)	0.3	0.7	1.6	0.1	-0.7	-0.3	-0.9	-1.0	-0.8	-1.0	-1.0	-0.9	-1.3	-0.7
Qualifications: CSEs or equivalent	0.3	0.4	2.7	-0.2	-0.2	-1.6	-0.4	-0.1	-0.7	-0.3	-0.3	-0.1	-0.3	-1.0
High blood pressure	0.3	0.7	3.1	1.5	-0.5	1.8	-0.3	-0.7	0.8	-0.5	-0.5	-0.2	-0.5	-0.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	0.9	-0.6	0.4	0.3	-0.8	0.9	-0.1	0.1	0.3	0.4	-0.8	1.0
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.5	-1.2	-0.7	-0.6	-0.4	-0.1	-0.3	-0.4	-0.6	-0.5	-0.5	-0.4
Father’s age at death	0.3	0.4	2.1	1.1	-0.1	1.5	0.2	-0.2	-0.1	0.2	0.0	0.0	0.7	-0.3
Number of live births	0.3	0.4	1.0	-0.0	-0.5	-0.9	-1.0	-0.6	0.1	-0.6	-0.5	-0.6	-0.9	-0.1
Qualifications: A levels/AS levels or equivalent	0.3	0.6	3.6	-1.9	0.2	-1.0	0.5	0.4	0.2	0.2	0.4	0.2	-0.1	1.0
Standing height	0.3	2.9	10.5	-2.0	-1.1	-2.0	-1.6	-0.4	-3.2	-1.4	-1.2	-1.6	-0.1	-1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.3	1.1	-0.5	0.7	-0.3	-0.0	-0.5	-0.8	-0.7	-0.8	-0.8	-0.3
Blood clot in the leg (DVT)	0.3	0.3	1.9	1.4	-0.2	0.4	0.6	-0.7	0.7	0.1	-0.4	-0.1	0.1	-0.5
Headache pain in last month	0.3	0.6	2.2	0.6	-0.7	-0.1	-0.5	-0.7	0.7	-0.9	-0.8	-0.7	-1.5	-0.2
Gout (self-reported)	0.3	0.4	2.4	0.6	0.0	-0.1	0.6	-0.8	1.6	0.0	-0.4	0.1	-0.7	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.8	-0.9	0.6	-0.1	0.5	0.6	-0.3	0.7	0.6	0.7	0.4	0.5
Age at first live birth	0.3	0.5	1.7	1.3	-0.4	0.9	-1.1	0.3	-1.2	0.1	0.2	0.3	-0.1	-0.5
Emphysema/chronic bronchitis	0.3	0.3	0.8	-0.7	-0.2	-0.9	-0.1	-0.4	-0.6	-0.4	-0.5	-0.5	0.5	-0.9
Medication for pain relief, constipation, heartburn	0.3	0.5	2.9	-0.9	-0.2	-0.8	-0.8	-0.0	-1.7	-0.4	-0.3	-0.5	-0.2	-0.7
Medication: Allopurinol	0.3	0.3	1.1	0.7	0.1	-0.2	0.4	-0.8	1.1	-0.0	-0.4	0.1	-1.1	0.3
Heart disease (mother)	0.3	0.3	1.5	-1.2	-0.3	-0.9	-0.4	-0.7	0.5	-0.2	-0.3	0.0	-0.4	-0.5
Mood swings	0.3	0.5	1.3	-0.0	0.6	1.1	0.5	0.8	0.7	0.5	0.8	0.8	0.5	0.7
Friendships satisfaction	0.3	0.3	1.7	0.7	-0.6	1.3	-0.3	0.3	-0.2	-0.4	-0.3	-0.4	-0.5	-0.3
Eye problems/disorders: Cataract	0.3	0.4	1.7	-1.3	0.4	-0.6	0.1	-0.4	1.2	0.0	-0.1	0.2	-0.5	0.3
Asthma (self-reported)	0.3	0.6	2.1	-1.0	0.6	-0.5	0.5	1.2	0.7	0.6	0.6	0.4	-0.4	1.5
Osteoarthritis (self-reported)	0.3	0.3	2.3	-0.1	0.4	0.2	0.6	-0.5	1.5	0.3	0.2	0.2	-0.1	0.6
Hearing aid user	0.3	0.4	1.6	-1.3	-0.1	-1.0	-0.7	-0.0	0.2	-0.1	-0.2	0.0	-0.9	0.3
Medication: Paracetamol	0.3	0.5	1.6	-0.5	0.8	-0.5	-0.0	0.7	0.6	0.8	0.8	1.3	0.5	0.6
Illnesses of father: High blood pressure	0.3	0.4	1.1	-1.0	0.6	-1.0	-0.2	0.5	0.3	0.5	0.6	0.6	0.3	0.5
Myopia	0.3	0.4	1.8	0.1	0.5	0.1	1.3	0.1	0.9	0.5	0.4	0.3	1.0	0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.7	1.3	-0.3	0.3	0.6	-0.9	0.7	0.0	-0.5	-0.3	-0.2	-0.5
Worry (Nagel 2018)	0.2	0.4	1.5	-0.2	0.7	0.6	0.1	0.7	0.6	0.6	0.8	0.7	-0.2	1.2
Crohns Disease (2017)	0.2	0.4	1.4	-1.2	-0.1	-0.8	-0.9	-0.1	-0.6	-0.4	-0.2	-0.3	-0.6	0.1
Ulcerative Colitis (UC)	0.2	0.4	1.1	0.5	-1.0	0.2	-1.0	-0.3	-0.5	-0.6	-0.5	-0.6	-0.7	-0.5
Prostate Cancer	0.2	0.3	0.8	-0.2	-0.1	-0.5	-0.8	-0.6	-0.8	-0.1	-0.2	0.2	0.4	-0.9
Age at First Birth	0.2	0.3	0.9	0.5	0.7	0.3	0.3	0.6	0.4	0.4	0.6	0.8	1.0	0.1
Neuroticism (2016)	0.2	0.3	1.3	0.6	-0.5	0.3	-0.2	0.1	-0.4	-0.6	-0.6	-0.6	-1.1	-0.2
Schizophrenia (2014)	0.2	0.4	2.5	0.5	-0.5	0.6	-0.7	-0.6	0.8	-0.2	-0.4	0.1	-1.6	0.1
Heel T-Score	0.2	1.4	4.3	-0.1	1.0	1.0	1.5	0.5	0.5	1.4	1.4	1.3	2.1	0.6
Height	0.2	3.3	11.6	-0.4	-1.4	-1.0	-1.6	-0.7	-3.4	-1.9	-1.6	-2.0	0.4	-2.8
Waist Hip Ratio (WHR)	0.2	0.9	2.3	-1.5	-0.6	-1.3	-1.2	0.0	-1.4	-0.8	-0.6	-0.7	-0.7	-0.6
Systolic Blood Pressure	0.2	0.8	2.8	1.7	0.8	1.0	1.0	0.8	0.8	0.8	0.6	0.6	0.8	0.6
Smoking Status	0.2	0.5	1.3	-0.5	0.9	-0.8	0.2	1.1	0.5	0.6	0.8	0.6	0.1	1.2
Chronotype (morning person)	0.2	0.6	1.1	-1.0	0.7	0.3	0.6	0.6	-0.1	1.0	1.0	0.7	0.9	0.6
Relative age of first facial hair	0.2	0.4	1.6	1.3	-0.1	-0.1	-0.1	0.8	-0.5	0.1	0.4	-0.1	-0.5	1.0
Diabetes (father)	0.2	0.2	0.9	-0.6	-0.0	0.6	0.6	-0.4	0.1	0.2	-0.1	0.2	0.9	-0.5
Pack years adult smoking proportion	0.2	0.3	1.3	-0.4	-0.3	-1.1	-0.6	-0.1	-0.6	-0.6	-0.4	-0.5	-0.3	-0.8
Average weekly fortified wine intake	0.2	0.3	2.5	-1.6	0.4	-0.3	-0.1	0.2	0.4	0.1	0.1	0.2	0.0	0.3
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.9	0.1	0.4	0.8	0.2	0.9	-0.6	0.7	0.7	0.4	0.5	0.8
Supplements: Glucosamine	0.2	0.2	2.2	0.1	0.1	1.5	0.3	-0.3	0.1	0.2	0.2	0.1	-0.0	0.3
Nervous feelings	0.2	0.3	1.0	-1.0	-0.5	-0.4	-0.7	-0.6	-0.3	-0.5	-0.3	-0.2	-0.9	0.1
Hearing difficulty/problems with background noise	0.2	0.3	1.2	-0.4	0.0	0.1	0.2	0.1	1.0	0.1	-0.2	-0.1	-1.1	0.7
Allergy	0.2	0.5	1.8	-0.3	-0.6	-0.5	-0.5	-1.3	0.1	-0.9	-0.8	-0.5	-0.4	-1.2
Neuroticism score	0.2	0.4	2.3	0.8	0.0	1.5	-0.7	-0.4	-0.0	-0.2	-0.0	0.3	-0.7	0.1
Trunk fat-free mass	0.2	1.0	1.9	-1.0	-0.9	-1.2	-0.6	-1.0	-1.3	-1.0	-1.0	-1.2	-0.3	-1.4
Noisy workplace	0.2	0.2	1.0	-0.5	0.3	-0.5	0.3	-0.3	1.0	0.6	0.3	0.5	0.1	0.2
Trunk predicted mass	0.2	1.0	1.9	-1.0	-0.9	-1.1	-0.6	-1.0	-1.3	-1.0	-1.0	-1.2	-0.3	-1.4
Breastfed as a baby	0.2	0.3	2.0	-0.2	-0.1	-0.6	0.2	-0.6	1.4	-0.3	-0.3	-0.3	0.3	-0.2
Hair/balding pattern: Pattern 4	0.2	0.5	1.7	-0.3	-0.5	-0.7	-0.6	-1.1	-0.7	-0.7	-0.6	-0.1	0.1	-1.3
Peak expiratory flow (PEF)	0.2	0.5	2.1	-1.4	0.1	-1.1	-0.7	0.6	-1.1	0.2	0.2	0.1	-0.4	0.2
Loud music exposure frequency	0.2	0.2	0.7	-0.8	-0.2	-0.6	-0.4	-0.2	-0.4	-0.2	-0.2	-0.2	-0.5	0.0
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.7	-0.7	0.2	0.3	0.8	0.3	-0.1	0.5	0.6	0.6	0.7	0.3
Medication: Amlodipine	0.2	0.3	0.9	0.7	-0.2	0.4	0.2	-1.0	0.2	-0.7	-0.5	-0.5	-0.3	-0.4
Birth weight	0.2	0.3	0.8	-0.9	0.4	-0.4	0.3	0.5	-0.8	0.4	0.8	0.3	-0.1	0.9
Wheeze or whistling in the chest in last year	0.2	0.3	1.1	-1.1	0.1	-0.4	0.9	0.4	0.9	-0.1	-0.1	-0.2	0.2	0.2
Family relationship satisfaction	0.2	0.2	0.7	0.4	-0.2	0.8	-0.4	0.6	-0.7	-0.1	0.1	-0.1	0.1	-0.1
Smoking status: Previous	0.2	0.3	1.2	-1.0	-0.3	-1.1	-0.5	-0.4	-0.2	-0.5	-0.2	-0.4	-0.4	-0.1
Loneliness, isolation	0.2	0.3	0.8	-0.4	-0.3	0.2	-0.7	-0.5	-0.5	-0.7	-0.4	-0.6	-0.9	-0.2
Long-standing illness, disability or infirmity	0.2	0.2	0.9	0.6	0.4	0.1	0.3	1.0	-0.1	0.5	0.5	0.2	0.7	0.5
Mineral and other dietary supplements	0.2	0.2	1.4	-0.7	-0.1	-1.2	-0.4	0.4	-0.4	0.1	0.0	0.1	-0.1	-0.1
Breast cancer (self-reported)	0.2	0.3	2.0	-1.4	0.1	-0.5	-0.3	-0.1	0.3	0.2	0.2	0.3	-0.4	0.4
Osteoporosis (self-reported)	0.2	0.2	1.2	1.1	-0.1	0.5	0.3	-0.5	0.5	-0.1	-0.1	0.2	0.1	-0.1
Illnesses of father: None of the above (group 1)	0.2	0.2	0.7	0.7	-0.4	0.6	-0.1	0.1	-0.8	-0.4	-0.5	-0.5	-0.1	-0.5
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.5	-0.8	0.5	-1.2	0.6	0.8	-0.6	0.7	0.7	0.4	0.8	0.3
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.7	0.5	-0.6	0.1	-0.1	-0.8	0.8	-0.3	-0.7	-0.4	-0.3	-0.6
Pain experienced in last month	0.2	0.4	1.1	-0.7	0.4	-0.1	0.1	1.1	-0.8	0.5	0.7	0.4	0.6	0.5
Alcohol drinker status: Previous	0.2	0.2	0.6	0.6	0.1	0.8	-0.6	-0.4	-0.5	0.0	0.0	0.2	-0.0	-0.3
Bipolar Disorder (2018)	0.1	0.2	1.2	-0.3	-0.2	0.1	-1.1	-0.3	-0.5	-0.1	-0.1	0.2	-0.5	-0.2
Neuroticism (Nagel 2018)	0.1	0.2	1.2	-0.1	-0.1	0.3	-0.7	-0.2	-0.2	-0.5	-0.2	-0.2	-1.1	0.3
Irritable Bowel Disease (IBD)	0.1	0.2	0.7	-0.8	-0.4	-0.6	-0.9	-0.1	-0.3	-0.4	-0.2	-0.3	-0.7	0.0
Breast Cancer	0.1	0.2	1.2	1.1	-0.1	0.6	0.1	0.1	-0.5	0.2	0.2	0.1	0.6	-0.3
Ovarian Cancer	0.1	0.1	0.7	0.4	0.2	0.9	0.1	-0.1	0.1	0.1	-0.0	-0.0	-0.3	0.5
Crohns Disease (2012)	0.1	0.2	1.1	-1.0	0.4	-0.5	-0.1	0.2	-0.2	0.2	0.4	0.4	0.1	0.4
Ulcerative Colitis	0.1	0.1	0.3	-0.4	-0.1	-0.6	-0.2	0.1	0.1	0.2	0.2	0.5	-0.2	-0.1
Blood Eosinophil Count	0.1	1.0	2.1	0.6	0.8	1.3	1.3	0.6	1.3	0.9	0.9	1.0	0.6	1.4
Blood Platelet Count	0.1	0.6	2.9	1.7	-0.5	0.9	-0.6	-0.5	-0.5	-0.7	-0.7	-0.5	-0.6	-0.6
Neuroticism	0.1	0.3	1.3	-0.3	-0.2	0.3	-1.0	-0.5	-0.3	-0.5	-0.3	-0.2	-1.1	0.0
Hand grip strength (left)	0.1	0.2	0.8	-0.1	0.2	0.2	-0.0	0.3	0.9	0.4	0.4	0.4	-0.1	0.5
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.5	0.7	0.2	0.6	0.3	-0.1	-0.1	0.5	0.2	0.2	0.6	0.0
Systolic blood pressure, automated reading	0.1	0.4	1.2	1.1	-0.4	0.8	0.5	-0.5	0.8	-0.2	-0.5	-0.6	0.1	-0.4
Impedance of leg (right)	0.1	0.4	2.0	-1.0	-0.1	-1.4	-0.4	0.5	-0.2	-0.5	-0.4	-0.3	-0.2	-0.1
Leg fat-free mass (left)	0.1	0.6	2.2	0.1	0.7	0.9	0.6	0.6	-0.9	0.9	0.8	0.7	1.5	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	-0.0	0.3	0.4	-0.2	0.2	0.3	0.3	0.3	0.4	0.0	0.0
Sitting height	0.1	0.8	4.4	-0.4	-0.8	-0.1	-0.7	0.2	-2.1	-0.7	-0.7	-1.0	0.3	-1.1
Impedance of leg (left)	0.1	0.4	1.5	-1.2	0.1	-1.2	-0.4	0.9	-0.1	-0.3	-0.1	-0.0	-0.0	0.1
Leg predicted mass (left)	0.1	0.6	1.9	0.1	0.6	0.9	0.5	0.5	-0.9	0.8	0.7	0.6	1.4	-0.2
Number of incorrect matches in round	0.1	0.1	0.6	-0.1	0.1	-0.3	0.8	0.1	0.4	0.1	-0.1	-0.1	0.2	0.2
Past tobacco smoking	0.1	0.1	0.3	0.4	-0.3	0.6	0.2	-0.2	-0.3	-0.2	-0.4	-0.2	-0.2	-0.4
Alcohol usually taken with meals	0.1	0.2	0.9	-0.9	0.3	-0.5	-0.3	0.1	-0.6	0.4	0.3	0.3	0.0	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.6	-0.3	-0.8	-0.5	-0.1	-0.7	0.6	-0.5	-0.7	-0.6	-0.1	-0.8
Impedance of arm (right)	0.1	0.7	4.9	0.3	0.1	0.3	-0.9	1.0	-2.2	-0.0	0.3	0.1	0.2	-0.1
Alcohol intake versus 10 years previously	0.1	0.2	0.6	0.8	0.1	-0.3	0.0	0.6	-0.7	-0.4	-0.2	-0.6	0.3	-0.3
Impedance of arm (left)	0.1	0.4	2.4	0.1	0.4	0.5	-0.5	1.0	-1.6	0.3	0.5	0.3	0.5	0.2
Birth weight of first child	0.1	0.2	1.2	0.1	-0.5	0.1	-0.1	-0.6	-1.1	-0.1	-0.0	-0.7	0.0	-0.5
Exposure to tobacco smoke outside home	0.1	0.1	0.4	0.7	0.4	0.3	-0.1	0.3	0.5	0.2	0.1	0.4	-0.1	0.2
Number of children fathered	0.1	0.1	0.9	-0.1	-0.2	-0.0	0.3	0.1	1.0	0.3	-0.1	0.1	0.2	-0.2
Qualifications: College or University degree	0.1	0.2	0.9	0.1	0.2	0.2	-0.1	0.4	-0.3	0.6	0.6	1.0	0.1	0.5
Medication: Ibuprofen	0.1	0.1	0.2	0.2	0.2	0.3	-0.0	0.3	0.2	0.3	0.3	0.4	-0.1	0.4
Medication: Omeprazole	0.1	0.1	0.6	0.8	-0.1	-0.0	-0.2	-0.4	0.2	-0.1	-0.3	-0.2	-0.2	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.5	0.3	-0.4	0.1	0.3	-0.4	0.3	-0.1	-0.2	0.0	0.6	-0.7
Alcohol intake frequency.	0.1	0.3	0.7	0.6	-0.5	-0.1	-0.3	-0.0	-0.2	-0.6	-0.6	-0.8	-0.8	-0.4
Comparative height size at age 10	0.1	0.4	1.2	-1.1	0.2	0.3	0.7	0.1	-0.9	0.0	0.1	-0.1	1.1	-0.3
Suffer from ‘nerves’	0.1	0.1	0.4	-0.2	-0.1	-0.1	-0.6	0.1	-0.6	-0.2	-0.1	-0.0	-0.2	-0.2
Chest pain or discomfort	0.1	0.2	1.3	0.2	-0.3	-0.4	-1.1	0.1	-0.4	-0.2	-0.2	-0.0	-0.3	-0.4
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.2	-0.4	0.2	0.4	0.2	0.2	0.2	0.1	0.2	0.0	0.2	0.4
Leg fat-free mass (right)	0.1	0.5	1.5	0.1	0.5	1.1	0.3	0.5	-1.1	0.7	0.7	0.6	1.2	-0.3
Average weekly red wine intake	0.1	0.2	0.7	0.3	-0.2	0.5	0.7	0.2	0.1	0.2	0.1	-0.4	-0.4	0.8
Medication for cholesterol	0.1	0.2	0.6	0.8	0.2	-0.1	0.2	0.5	-0.5	0.1	0.3	0.3	0.6	-0.1
Leg predicted mass (right)	0.1	0.5	1.3	0.1	0.5	1.0	0.2	0.5	-1.2	0.7	0.6	0.5	1.1	-0.3
Guilty feelings	0.1	0.1	0.6	-0.3	0.3	0.7	-0.4	0.1	-0.5	0.0	0.1	0.2	-0.0	0.0
Ever smoked	0.1	0.3	0.5	-0.7	0.6	-0.7	0.1	0.6	0.4	0.4	0.5	0.2	0.3	0.7
Average weekly beer plus cider intake	0.1	0.2	0.4	0.0	-0.3	-0.4	-0.5	-0.6	-0.1	-0.4	-0.3	-0.3	-0.7	-0.4
Cholesterol lowering medication	0.1	0.1	0.8	-0.1	-0.1	-0.2	0.3	-0.2	0.9	-0.2	-0.2	-0.1	-0.3	0.3
Supplements: Calcium	0.1	0.1	1.1	0.5	-0.0	0.2	-0.1	0.1	-1.0	-0.1	0.2	-0.2	0.2	0.2
Heart disease (siblings)	0.1	0.1	0.4	0.0	-0.5	-0.5	0.1	-0.6	0.3	-0.2	-0.3	-0.6	-0.3	-0.2
Impedance of whole body	0.1	0.3	1.4	-0.4	0.4	-0.2	-0.3	1.2	-0.8	0.2	0.4	0.3	0.5	0.3
Lung FEV1/FVC ratio	0.0	0.2	1.1	-0.4	-0.3	-0.1	-0.7	0.3	-1.0	0.3	0.1	0.2	0.0	-0.3
Hair Pigment	0.0	0.6	2.2	0.1	0.6	-1.0	-0.5	1.4	-1.5	0.3	0.6	0.2	0.2	0.5
Tanning	0.0	0.1	0.8	-0.1	0.1	-0.9	0.2	-0.0	0.5	0.0	0.0	0.1	-0.3	0.3
Hand grip strength (right)	0.0	0.1	0.2	-0.5	0.1	-0.2	0.0	0.1	0.2	0.4	0.4	0.4	0.1	0.3
Arm fat-free mass (right)	0.0	0.2	0.7	-0.8	0.2	-0.1	0.5	0.0	0.1	0.3	0.1	0.0	0.9	-0.3
Worry too long after embarrassment	0.0	0.1	0.3	-0.5	0.2	0.3	-0.2	-0.3	0.1	-0.1	-0.1	0.5	-0.2	-0.1
Arm predicted mass (right)	0.0	0.2	0.8	-0.9	0.4	-0.1	0.6	0.1	0.1	0.4	0.2	0.1	0.9	-0.2
Whole body fat-free mass	0.0	0.2	1.1	-0.5	-0.2	-0.1	-0.1	-0.3	-1.1	-0.1	-0.2	-0.4	0.5	-0.9
Whole body water mass	0.0	0.3	1.1	-0.5	-0.3	-0.1	-0.1	-0.3	-1.1	-0.2	-0.2	-0.4	0.4	-0.9
Basal metabolic rate	0.0	0.2	0.9	-0.5	0.3	0.3	0.4	0.1	-0.7	0.3	0.3	0.1	1.0	-0.4
Arm fat-free mass (left)	0.0	0.1	0.4	-0.6	0.1	-0.1	0.5	-0.1	-0.1	0.2	0.1	-0.1	0.7	-0.3
Arm predicted mass (left)	0.0	0.1	0.6	-0.8	-0.1	-0.3	0.3	-0.1	-0.3	0.1	-0.1	-0.2	0.6	-0.5

Hub : Genes

TEKT3

Models

Trait associations