Best TWAS P=1.36e-19 · Best GWAS P=1.21e-15 conditioned to 0.392
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RAD51AP2 | 0.11 | 0.09 | bslmm | 416 | 0.06 | 2.5e-08 | -7.3 | 5.6 | 2.2e-08 | 0.49 | 0.34 | 0.66 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | VSNL1 | 0.05 | 0.00 | blup | 505 | 0.02 | 4.1e-03 | 2.5 | 6.3 | 2.4e-10 | 0.51 | 0.11 | 0.18 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RAD51AP2 | 0.01 | 0.01 | lasso | 3 | 0.01 | 3.3e-03 | -7.4 | 7.4 | 1.4e-13 | 0.44 | 0.10 | 0.26 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | RAD51AP2 | 0.05 | 0.01 | blup | 31 | 0.05 | 1.2e-03 | -7.2 | 9.1 | 1.4e-19 | 0.83 | 0.01 | 0.81 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | SMC6 | 0.03 | 0.02 | blup | 96 | 0.03 | 1.5e-03 | -3.4 | -5.7 | 1.1e-08 | -0.29 | 0.15 | 0.12 | FALSE |