[Hub]/) : Traits : Pulse rate, automated reading :

chr1:28,011,854-29,594,563

Best TWAS P=6.07e-09 · Best GWAS P=1.62e-08 conditioned to 0.0349

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta PHACTR4 0.26 0.27 lasso 8 0.21 8.7e-12 5.3 -5.7 1.5e-08 -0.96 0.03 0.97 FALSE
2 GTEx Artery Coronary PHACTR4 0.12 0.20 lasso 2 0.18 1.0e-06 5.3 -5.3 9.8e-08 -0.97 0.03 0.96 FALSE
3 GTEx Brain Cerebellum PHACTR4 0.20 0.14 lasso 16 0.13 1.4e-04 5.4 -5.3 8.9e-08 -0.98 0.02 0.95 FALSE
4 GTEx Brain Frontal Cortex BA9 PHACTR4 0.20 0.18 lasso 4 0.19 9.4e-06 4.8 -5.2 2.5e-07 -0.97 0.04 0.89 FALSE
5 GTEx Colon Transverse SNHG12 0.11 -0.01 lasso 5 0.00 6.7e-01 5.3 -5.8 6.1e-09 -0.72 0.03 0.71 TRUE
6 GTEx Spleen SNHG3 0.15 0.09 lasso 6 0.07 6.8e-03 5.3 5.4 5.3e-08 0.91 0.04 0.78 FALSE
7 NTR Blood PHACTR4 0.01 0.01 enet 8 0.01 2.6e-05 5.2 -5.1 2.8e-07 -0.79 0.02 0.97 FALSE
8 YFS Blood PHACTR4 0.14 0.28 bslmm 323 0.28 3.5e-92 5.5 -5.2 1.6e-07 -0.99 0.01 0.99 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PHACTR4 0.02 0.02 enet 3 0.02 2.9e-03 5.4 -5.5 3.2e-08 -0.93 0.02 0.80 FALSE