[Hub]/) : Traits : Pulse rate, automated reading : ← →

chr1:39,258,674-40,737,589

Best TWAS P=1.84e-11 · Best GWAS P=5.75e-09 conditioned to 0.235

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
34	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BMP8A	0.04	0.03	blup	48	0.04	3.5e-05	5.5	6.7	1.8e-11	0.75	0.01	0.98	TRUE
3	GTEx	Adrenal Gland	PABPC4	0.20	0.09	lasso	8	0.06	3.0e-03	5.8	-6.4	1.8e-10	-0.95	0.02	0.91	FALSE
11	GTEx	Breast Mammary Tissue	RP11-69E11.4	0.15	0.05	enet	32	0.05	8.8e-04	4.9	6.3	2.6e-10	0.63	0.14	0.83	FALSE
22	GTEx	Nerve Tibial	RP11-69E11.8	0.05	0.00	lasso	3	0.01	6.9e-02	5.8	-6.0	1.7e-09	-0.99	0.02	0.90	FALSE
16	GTEx	Esophagus Mucosa	RP11-69E11.4	0.18	0.06	lasso	9	0.07	2.2e-05	5.5	6.0	2.0e-09	0.77	0.06	0.94	FALSE
4	GTEx	Adrenal Gland	RP11-69E11.4	0.11	0.05	lasso	3	0.00	2.4e-01	5.6	5.9	2.8e-09	0.76	0.03	0.72	FALSE
15	GTEx	Esophagus Mucosa	PABPC4	0.06	0.06	lasso	3	0.08	7.3e-06	5.6	-5.9	3.0e-09	-0.98	0.01	0.99	FALSE
6	GTEx	Artery Tibial	PABPC4	0.10	0.10	lasso	4	0.10	3.4e-08	5.8	-5.9	3.2e-09	-0.99	0.00	1.00	FALSE
25	GTEx	Skin Sun Exposed Lower leg	RP11-69E11.4	0.13	0.12	lasso	6	0.15	1.3e-12	4.9	5.9	3.6e-09	0.75	0.17	0.83	FALSE
21	GTEx	Nerve Tibial	RP11-69E11.4	0.18	0.08	lasso	5	0.18	1.3e-12	4.7	5.9	4.6e-09	0.88	0.03	0.97	FALSE
36	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PABPC4	0.04	0.05	blup	31	0.04	1.2e-05	5.5	-5.8	4.9e-09	-0.84	0.01	0.99	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	PABPC4	0.03	0.03	lasso	2	0.04	1.3e-08	5.8	-5.8	5.1e-09	-0.92	0.00	1.00	FALSE
12	GTEx	Cells Transformed fibroblasts	PABPC4	0.07	0.09	lasso	1	0.06	2.7e-05	5.8	-5.8	5.8e-09	-1.00	0.01	0.99	FALSE
40	The Cancer Genome Atlas	Thyroid Carcinoma	PABPC4	0.09	0.07	enet	5	0.08	4.1e-08	5.8	-5.8	6.3e-09	-0.87	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	BMP8A	0.05	0.01	lasso	6	0.02	5.5e-05	5.6	5.8	6.6e-09	0.81	0.00	0.99	FALSE
26	GTEx	Spleen	RP11-69E11.4	0.25	0.12	lasso	4	0.15	9.3e-05	5.5	5.8	6.7e-09	0.73	0.08	0.83	FALSE
39	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPIEL	0.04	0.02	lasso	4	0.02	1.7e-03	5.5	5.8	7.3e-09	0.74	0.02	0.80	FALSE
23	GTEx	Skin Not Sun Exposed Suprapubic	PABPC4	0.12	0.10	lasso	3	0.05	1.0e-03	5.6	-5.8	7.4e-09	-0.97	0.01	0.98	FALSE
9	GTEx	Brain Frontal Cortex BA9	RP11-69E11.4	0.23	0.10	lasso	6	0.11	7.2e-04	5.5	5.8	9.1e-09	0.71	0.04	0.77	FALSE
1	CommonMind	Brain Pre-frontal Cortex	BMP8A	0.05	0.03	lasso	3	0.02	8.8e-04	5.6	5.7	1.1e-08	0.98	0.02	0.96	FALSE
24	GTEx	Skin Sun Exposed Lower leg	PABPC4	0.11	0.09	lasso	7	0.08	2.7e-07	5.6	-5.7	1.2e-08	-0.96	0.01	0.99	FALSE
37	The Cancer Genome Atlas	Lung Adenocarcinoma	PABPC4	0.04	0.03	enet	8	0.04	4.5e-05	5.6	-5.7	1.3e-08	-0.93	0.00	0.99	FALSE
14	GTEx	Colon Transverse	RP11-69E11.4	0.23	0.12	lasso	4	0.15	1.8e-07	5.6	5.7	1.4e-08	0.89	0.02	0.98	FALSE
19	GTEx	Lung	PABPC4	0.05	0.03	lasso	3	0.02	1.3e-02	5.8	-5.7	1.4e-08	-0.96	0.02	0.95	FALSE
30	NTR	Blood	PABPC4	0.01	0.00	blup	383	0.00	2.8e-02	5.8	-5.7	1.5e-08	-0.73	0.02	0.82	FALSE
2	GTEx	Adipose Subcutaneous	BMP8A	0.06	0.05	lasso	1	0.04	3.5e-04	5.6	5.6	1.8e-08	0.70	0.02	0.88	FALSE
7	GTEx	Artery Tibial	RP11-69E11.4	0.15	0.16	lasso	6	0.16	8.3e-13	5.5	5.5	3.3e-08	0.76	0.03	0.97	FALSE
35	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PABPC4	0.03	0.01	enet	4	0.02	4.3e-03	5.8	-5.5	4.0e-08	-0.98	0.00	0.98	FALSE
29	METSIM	Adipose	PABPC4	0.05	0.02	lasso	6	0.03	6.0e-05	5.6	-5.5	4.3e-08	-0.89	0.02	0.98	FALSE
28	GTEx	Thyroid	RP11-69E11.4	0.17	0.04	lasso	9	0.06	4.4e-05	5.5	5.4	5.6e-08	0.81	0.02	0.95	FALSE
13	GTEx	Colon Sigmoid	RP11-69E11.4	0.20	0.16	lasso	5	0.20	1.1e-07	4.8	5.4	6.2e-08	0.78	0.17	0.81	FALSE
27	GTEx	Stomach	RP11-69E11.4	0.31	0.20	lasso	4	0.20	4.0e-10	5.5	5.4	7.3e-08	0.74	0.03	0.97	FALSE
10	GTEx	Breast Mammary Tissue	PABPC4	0.13	0.02	enet	14	0.04	3.4e-03	5.6	-5.4	7.6e-08	-0.93	0.02	0.95	FALSE
18	GTEx	Heart Left Ventricle	RP11-69E11.4	0.10	0.10	lasso	4	0.08	3.8e-05	5.5	5.4	8.0e-08	0.69	0.05	0.92	FALSE
38	The Cancer Genome Atlas	Prostate Adenocarcinoma	BMP8A	0.07	0.06	enet	7	0.07	5.8e-08	4.1	5.3	1.2e-07	0.67	0.04	0.96	FALSE
33	The Cancer Genome Atlas	Esophageal Carcinoma	BMP8A	0.15	0.08	blup	41	0.10	4.0e-04	4.1	5.2	1.8e-07	0.59	0.05	0.77	FALSE
5	GTEx	Artery Aorta	RP11-69E11.4	0.13	0.10	enet	14	0.14	2.5e-08	5.6	5.2	2.0e-07	0.86	0.02	0.98	FALSE
17	GTEx	Esophagus Muscularis	BMP8A	0.08	0.05	enet	10	0.05	3.5e-04	4.1	5.2	2.0e-07	0.77	0.12	0.84	FALSE
20	GTEx	Nerve Tibial	PABPC4	0.17	0.08	enet	12	0.05	2.7e-04	5.8	-5.2	2.3e-07	-0.85	0.01	0.99	FALSE
8	GTEx	Brain Cerebellar Hemisphere	RP11-69E11.4	0.22	0.08	enet	16	0.08	4.5e-03	5.5	5.2	2.4e-07	0.71	0.09	0.77	FALSE