Best TWAS P=4.42e-25 · Best GWAS P=4.32e-25 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2 | GTEx | Heart Atrial Appendage | AC007620.3 | 0.52 | 0.44 | lasso | 2 | 0.42 | 2.1e-20 | -10.3 | -10.3 | 4.4e-25 | 1.00 | 0.00 | 1.00 | TRUE |
| 5 | GTEx | Heart Left Ventricle | AC007620.3 | 0.43 | 0.32 | lasso | 4 | 0.32 | 2.3e-17 | -10.3 | -10.3 | 6.1e-25 | 0.99 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Heart Atrial Appendage | RP11-145M9.4 | 0.56 | 0.48 | lasso | 3 | 0.48 | 2.0e-24 | -10.3 | -10.3 | 6.4e-25 | 1.00 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Heart Left Ventricle | GNB4 | 0.45 | 0.28 | lasso | 3 | 0.35 | 3.0e-19 | -10.3 | -10.3 | 8.7e-25 | 0.99 | 0.00 | 1.00 | FALSE |
| 1 | GTEx | Heart Atrial Appendage | GNB4 | 0.56 | 0.45 | lasso | 3 | 0.42 | 1.3e-20 | -10.3 | -10.2 | 3.2e-24 | 0.99 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Heart Left Ventricle | RP11-145M9.4 | 0.43 | 0.32 | lasso | 5 | 0.32 | 8.0e-18 | -10.3 | -10.1 | 8.6e-24 | 0.98 | 0.00 | 1.00 | FALSE |
| 7 | GTEx | Skin Not Sun Exposed Suprapubic | RP11-255C15.4 | 0.12 | 0.06 | lasso | 2 | 0.07 | 6.9e-05 | -3.4 | -6.5 | 1.1e-10 | 0.64 | 0.02 | 0.92 | FALSE |