Best TWAS P=9.56e-10 · Best GWAS P=3.26e-12 conditioned to 1.97e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ECE2 | 0.24 | 0.20 | bslmm | 542 | 0.19 | 1.6e-22 | -6.1 | -6.0 | 2.7e-09 | 0.82 | 0.21 | 0.79 | FALSE |
| 2 | GTEx | Nerve Tibial | ABCC5 | 0.24 | 0.11 | enet | 40 | 0.12 | 4.8e-09 | 3.2 | 5.2 | 2.4e-07 | -0.30 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Pancreas | ECE2 | 0.26 | 0.04 | enet | 24 | 0.09 | 1.2e-04 | -6.1 | -5.5 | 3.8e-08 | 0.63 | 0.03 | 0.82 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ECE2 | 0.04 | 0.02 | blup | 61 | 0.03 | 3.5e-04 | -6.1 | -5.9 | 3.3e-09 | 0.74 | 0.01 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | PSMD2 | 0.09 | 0.02 | blup | 50 | 0.05 | 1.2e-06 | 3.7 | -6.1 | 9.6e-10 | 0.56 | 0.04 | 0.82 | TRUE |
| 6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | VWA5B2 | 0.10 | 0.04 | blup | 51 | 0.04 | 1.8e-02 | -3.7 | 5.4 | 6.2e-08 | -0.68 | 0.03 | 0.42 | FALSE |