Best TWAS P=1.2e-10 · Best GWAS P=1.2e-16 conditioned to 1.5e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | BNIP1 | 0.18 | 0.08 | lasso | 5 | 0.13 | 2.1e-10 | 2.5 | -5.6 | 2.0e-08 | 0.22 | 0.96 | 0.04 | FALSE |
| 2 | GTEx | Nerve Tibial | BNIP1 | 0.18 | 0.05 | lasso | 6 | 0.10 | 1.5e-07 | 2.5 | -5.7 | 1.4e-08 | 0.20 | 0.74 | 0.24 | FALSE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | BNIP1 | 0.11 | 0.03 | blup | 49 | 0.09 | 3.3e-05 | 2.5 | -6.2 | 6.9e-10 | 0.19 | 0.04 | 0.90 | TRUE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | ATP6V0E1 | 0.08 | 0.00 | blup | 59 | 0.02 | 2.4e-02 | -6.6 | 6.4 | 1.2e-10 | -0.34 | 0.01 | 0.34 | TRUE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | BNIP1 | 0.06 | 0.04 | enet | 6 | 0.01 | 3.0e-02 | 2.5 | -5.2 | 1.8e-07 | 0.29 | 0.03 | 0.19 | FALSE |