TWAS hub - ATP6V0E1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Brain Lower Grade Glioma	0.0542	0.0308	0.0016	0.000	0.017	0.006	NA	0.003	0.32	0.004	0.054	NA	0.14
2	TCGA	Ovarian Serous Cystadenocarcinoma	0.0820	0.0430	0.0050	-0.004	0.017	0.012	NA	-0.004	0.88	0.024	0.048	NA	0.75

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Pulse rate	10.8	18.2	35.6	0.9	6.0
Pulse rate, automated reading	6.7	21.6	41.5	-1.3	6.4
Age started oral contraceptive pill	6.0	7.5	14.1	3.8	-1.0
Bipolar Disorder (2011)	5.1	4.9	9.7	0.3	-3.1
Chronic bronchitis/emphysema (father)	4.5	5.2	9.8	-0.8	3.1
Eye problems/disorders: None of the above	4.4	5.1	10.2	-3.2	-0.0
Medication: Paracetamol	4.1	6.7	12.6	-3.6	-0.9
Eye problems/disorders: Cataract	3.9	4.5	9.0	3.0	-0.0
Eye problems/disorders: Diabetes related eye disease	3.4	3.8	6.6	2.6	1.0
Illnesses of siblings: Diabetes	3.4	4.2	8.4	2.9	0.0
Medication: Atenolol	3.2	4.0	6.9	1.1	2.6
Supplements: Vitamin C	3.1	3.7	4.7	-1.6	2.2
Type 2 Diabetes (T2D) (2012)	3.0	3.4	6.5	2.5	-0.6
Osteoporosis (self-reported)	2.9	3.6	6.5	2.5	-0.8
Medication: Lansoprazole	2.8	3.2	5.6	0.9	2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.8	3.3	5.7	-1.0	2.4
Medication: Paracetamol	2.8	4.4	8.4	-2.9	-0.6
Financial difficulties in last 2 years	2.7	3.7	7.1	-2.7	-0.6
Hayfever/allergic rhinitis (self-reported)	2.7	3.5	6.7	2.6	0.6
Hip circumference	2.7	11.7	23.0	-4.8	-0.6
Loud music exposure frequency	2.7	3.0	5.7	-0.4	-2.4
Guilty feelings	2.7	4.1	4.5	-1.9	2.1
Bipolar Disorder (2018)	2.6	4.1	7.9	0.6	-2.8
Average weekly spirits intake	2.6	3.3	4.5	-1.4	2.1
Leg fat-free mass (left)	2.6	13.6	19.7	-4.4	-2.7
Leg predicted mass (left)	2.6	13.6	19.4	-4.4	-2.8
Medication: Ramipril	2.6	3.4	5.3	2.3	-1.2
Leg fat-free mass (right)	2.6	14.0	19.5	-4.4	-2.9
Leg predicted mass (right)	2.6	13.8	19.3	-4.4	-2.9
Ever had bowel cancer screening	2.5	2.9	3.1	1.8	1.7
Illnesses of father: None of the above (group 1)	2.4	2.9	4.7	-1.1	-2.2
Basal metabolic rate	2.4	13.2	19.3	-4.4	-2.7
Mean Putamen Volume	2.2	2.5	4.2	-0.9	2.0
Waist Hip Ratio (WHR)	2.2	10.0	19.2	4.4	-0.9
Medication: Metformin	2.2	3.1	5.2	2.3	-1.0
Whole body fat-free mass	2.2	12.8	18.0	-4.2	-2.8
Whole body water mass	2.2	12.7	17.6	-4.2	-2.8
Tinnitus: Yes, now most or all of the time	2.2	2.6	4.6	-0.8	-2.1
Commuting to job workplace: Public transport	2.2	2.7	5.2	-0.3	-2.3
Bipolar Disorder or Schizophrenia	2.1	5.1	8.7	1.2	-3.0
Medication: Co-codamol	2.1	2.4	3.9	2.0	-1.0
Comparative body size at age 10	2.1	5.8	10.6	1.0	-3.3
Financial situation satisfaction	2.1	2.6	3.1	-1.8	-1.5
Qualifications: CSEs or equivalent	2.0	2.7	4.4	2.1	-1.0
Gout (self-reported)	2.0	2.7	3.8	2.0	-1.3
Weight	1.9	9.4	14.6	-3.8	-2.0
Trunk fat-free mass	1.9	11.0	15.0	-3.9	-2.7
Trunk predicted mass	1.9	10.9	15.0	-3.9	-2.6
Pulse wave reflection index	1.9	2.4	4.3	0.7	-2.1
Arm fat-free mass (left)	1.9	9.9	14.5	-3.8	-2.3
Schizophrenia (2014)	1.8	4.1	7.9	0.5	-2.8
Townsend deprivation index at recruitment	1.8	2.5	4.2	2.1	-0.9
Had menopause	1.8	2.2	4.5	2.1	0.0
Diabetes (self-reported)	1.8	2.8	3.9	2.0	-1.3
Chronic bronchitis/emphysema (mother)	1.8	2.1	2.4	-1.3	1.6
Arm fat-free mass (right)	1.8	9.2	14.1	-3.8	-2.1
Shortness of breath walking on level ground	1.8	2.2	4.1	-2.0	0.6
Medication: Allopurinol	1.8	2.5	4.8	2.2	0.3
Overall health rating	1.8	3.8	7.4	0.5	2.7
Diabetes diagnosed by doctor	1.8	3.0	5.4	2.3	-0.8
Arm predicted mass (left)	1.8	9.1	13.8	-3.7	-2.1
Emphysema/chronic bronchitis	1.7	2.0	3.8	0.4	1.9
Neck or shoulder pain in last month	1.7	2.5	4.2	2.1	0.8
Wears glasses or contact lenses	1.7	2.0	3.6	0.7	1.9
Depression (Nagel 2018)	1.6	2.4	2.8	-1.4	-1.7
Diabetes (father)	1.6	2.0	2.5	-1.6	1.2
Average weekly fortified wine intake	1.6	1.8	3.6	-0.2	1.9
Sitting height	1.6	11.2	14.7	-3.8	-2.8
Fluid intelligence score	1.6	3.4	6.0	-0.9	2.5
Illnesses of siblings	1.6	2.2	2.3	-1.5	-1.5
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	4.0	-2.0	-0.0
Standing height	1.6	15.5	26.1	-2.2	-5.1
Mouth/teeth dental problems: Bleeding gums	1.6	2.0	2.4	1.5	-1.3
Arm predicted mass (right)	1.6	8.4	13.1	-3.6	-1.9
Eye problems/disorders: Glaucoma	1.6	1.9	2.9	1.0	-1.7
Vitamin and mineral supplements	1.5	2.0	2.6	1.2	-1.6
Supplements: Glucosamine	1.5	2.0	3.8	0.3	-2.0
Alcohol usually taken with meals	1.5	2.4	4.1	-0.8	2.0
Alcohol drinker status: Never	1.5	1.7	3.5	-0.1	1.9
Myopia	1.5	2.1	3.3	1.0	1.8
Frequency of depressed mood in last 2 weeks	1.4	2.0	3.0	-1.7	-1.0
Bilateral oophorectomy (both ovaries removed)	1.4	1.7	3.1	-0.5	-1.8
Number of full brothers	1.4	1.8	2.4	-1.1	-1.5
Medication for pain relief, constipation, heartburn	1.4	2.5	4.9	2.2	-0.0
Mean time to correctly identify matches	1.4	2.6	5.2	2.3	-0.2
Leg fat mass (right)	1.4	5.2	10.2	-3.2	-0.6
Illnesses of father: Heart disease	1.4	1.9	3.7	0.5	1.9
Smoking status: Current	1.4	2.2	4.4	-2.1	-0.2
Average weekly beer plus cider intake	1.4	2.0	2.9	-1.7	-1.0
Worrier / anxious feelings	1.3	2.5	3.6	1.1	1.9
Medication: Amlodipine	1.3	1.9	3.7	-0.2	-1.9
Arm fat mass (left)	1.3	5.2	9.8	-3.1	-0.8
Leg fat mass (left)	1.3	5.0	9.7	-3.1	-0.5
Ovarian Cancer	1.2	1.5	1.7	-1.2	1.3
Age at First Birth	1.2	1.8	3.5	-0.1	-1.9
Height	1.2	23.1	36.1	-3.2	-6.0
Chest pain or discomfort	1.2	1.8	1.9	1.4	-1.3
Medication: Gliclazide	1.2	1.4	2.5	1.6	0.5
Risk taking	1.2	1.7	3.0	-1.7	-0.7
Supplements: Calcium	1.2	1.4	2.7	-0.2	-1.6
Reaction Time	1.1	2.1	4.2	2.0	0.2
Crohns Disease (2012)	1.1	1.8	2.8	1.7	0.8
Systolic blood pressure, automated reading	1.1	3.3	3.3	1.8	-1.8
Body mass index (BMI)	1.1	4.5	8.9	-3.0	0.3
Prospective memory result	1.1	1.4	2.6	0.5	-1.6
Arm fat mass (right)	1.1	4.5	8.5	-2.9	-0.7
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	2.2	-1.5	-1.1
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	4.4	0.2	-2.1
High blood pressure (siblings)	1.1	1.6	2.0	1.4	1.1
Mouth/teeth dental problems: Loose teeth	1.1	1.3	1.5	1.2	1.0
Family relationship satisfaction	1.1	1.3	2.1	-1.4	-0.8
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.4	1.4	-1.2	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.4	2.8	-1.4	-1.7
Ever depressed for a whole week	1.1	1.3	2.7	1.6	0.0
Major Depression (MDD)	1.0	1.2	2.1	-0.5	-1.5
Prostate Cancer	1.0	1.4	2.3	-0.7	-1.5
Neuroticism (2016)	1.0	1.5	2.2	-0.9	-1.5
Primary Biliary Cirrhosis	1.0	1.5	2.4	1.5	-0.8
Systolic Blood Pressure	1.0	4.9	7.2	2.7	-1.6
Chronotype (morning person)	1.0	2.3	4.5	0.5	2.1
Medication for hormone replacement therapy	1.0	1.1	2.1	0.1	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	1.4	-1.1	-1.2
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	1.8	0.7	-1.3
Glaucoma (self-reported)	1.0	1.2	2.4	-0.2	-1.5
Birth weight	1.0	2.2	3.3	-1.8	-1.0
Whole body fat mass	1.0	4.0	7.5	-2.7	-0.7
Leg pain on walking	1.0	1.2	2.0	-1.4	-0.7
Loneliness, isolation	1.0	1.4	2.0	-1.4	-0.9
Commuting to job workplace: Walk	1.0	1.1	1.7	-1.3	0.7
Hearing aid user	1.0	1.1	1.8	-1.3	0.6
Fractured/broken bones in last 5 years	1.0	1.3	2.5	-0.2	-1.6
Heart disease (siblings)	1.0	1.3	2.3	0.5	1.5
Verbal and Numeric Reasoning (VNR)	0.9	2.2	4.2	-0.4	2.1
Rheumatoid Arthritis	0.9	1.2	2.2	-0.4	-1.5
Triglycerides	0.9	1.5	2.6	1.6	0.6
Hypothyroidism (self reported)	0.9	2.0	3.8	-0.4	-2.0
Type 2 Diabetes (T2D) (2018)	0.9	1.7	2.6	1.6	-0.9
Current tobacco smoking	0.9	1.5	2.6	-1.6	-0.6
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	1.1	1.0	1.0
High blood pressure (mother)	0.9	1.2	2.0	1.4	0.7
Impedance of leg (left)	0.9	4.3	8.1	2.9	0.7
Hair/balding pattern: Pattern 4	0.9	2.3	3.1	-1.8	1.2
Birth weight of first child	0.9	1.6	2.5	1.6	0.8
Medication for cholesterol	0.9	1.3	2.3	-1.5	-0.6
Pain type(s) experienced in last month: Hip pain	0.9	1.1	1.8	-0.6	-1.3
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.4	0.1	1.5
Medication: Lisinopril	0.9	1.2	1.6	-1.3	0.9
Impedance of whole body	0.9	4.8	9.6	3.1	0.2
Schizophrenia (2018)	0.8	1.7	2.3	1.1	-1.5
HbA1C	0.8	0.9	1.7	0.3	1.3
Allergy or Eczema	0.8	2.0	3.6	1.9	-0.6
Impedance of leg (right)	0.8	4.0	7.1	2.7	0.9
Trunk fat mass	0.8	3.6	6.2	-2.5	-1.0
Pain all over the body in last month	0.8	0.9	1.5	1.2	0.5
Time employed in main current job	0.8	0.9	1.8	1.3	0.3
Medication: Cholesterol lowering	0.8	1.3	2.3	-0.5	1.5
Number of full sisters	0.8	1.0	1.7	-1.3	-0.6
Medication: Aspirin	0.8	1.1	2.1	1.5	0.2
Mother’s age at death	0.8	1.0	1.7	1.3	-0.5
Medication: Blood pressure	0.8	1.4	2.2	1.5	-0.8
Medication: Bendroflumethiazide	0.8	1.2	2.2	1.5	-0.5
Diastolic blood pressure, automated reading	0.8	2.4	4.6	-0.5	2.1
Cholesterol lowering medication	0.8	1.1	1.9	1.4	0.7
Pain experienced in last month	0.8	1.4	1.7	-1.3	-1.0
Severe depression (siblings)	0.7	0.7	1.4	0.2	-1.2
Serious illness, injury or assault to yourself	0.7	0.8	1.1	-1.0	-0.8
Mouth/teeth dental problems	0.7	1.0	1.8	-1.3	0.6
Impedance of arm (right)	0.7	3.1	5.4	2.3	-0.9
Noisy workplace	0.7	0.9	1.2	-1.1	-0.8
Impedance of arm (left)	0.7	3.1	5.7	2.4	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	1.3	-1.0	-1.1
Headache pain in last month	0.7	1.3	1.4	-1.1	1.2
Worry too long after embarrassment	0.7	1.1	2.1	-0.4	1.4
Age at first live birth	0.7	1.2	1.9	0.8	-1.4
Medication: Blood pressure	0.7	1.3	1.6	1.3	1.0
Medication: Ibuprofen	0.7	0.9	1.8	-1.3	0.1
Ever taken oral contraceptive pill	0.7	0.8	1.3	1.1	0.6
High cholesterol (Self-reported)	0.7	1.3	2.7	0.1	1.6
Alcohol drinker status: Previous	0.7	0.8	1.3	-0.6	-1.1
Schizophrenia vs Biploar Disorder	0.6	0.8	1.6	0.1	-1.3
Ulcerative Colitis	0.6	0.9	1.1	1.0	-0.9
BMI	0.6	3.6	7.1	-2.7	-0.1
Relative age of first facial hair	0.6	1.2	2.2	0.4	-1.5
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.5	1.2	0.1
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	0.7	0.8	-0.8
Hayfever, allergic rhinitis or eczema	0.6	1.4	2.7	1.6	-0.1
Arm fat percentage (right)	0.6	2.3	4.3	-2.1	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	1.2	1.1	-0.9
Hair/balding pattern: Pattern 3	0.6	0.9	1.3	1.2	0.7
Number of live births	0.6	0.8	1.4	1.2	0.5
Illnesses of mother	0.6	0.8	1.0	-1.0	-0.7
Blood clot in the leg (DVT)	0.6	0.8	1.3	-0.6	1.1
Leg fat percentage (right)	0.6	2.0	3.8	-1.9	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.4	-0.4	-1.2
Qualifications: College or University degree	0.6	1.9	2.4	1.6	-1.2
Comparative height size at age 10	0.6	3.1	5.2	-1.0	-2.3
Arm fat percentage (left)	0.6	2.4	4.6	-2.2	-0.3
Number of self-reported non-cancer illnesses	0.6	1.0	2.1	1.4	0.2
Average weekly champagne plus white wine intake	0.6	0.9	1.5	-0.5	1.2
Number of operations (self-reported)	0.6	0.9	1.9	1.4	0.1
Basal cell carcinoma (self-reported)	0.6	0.7	1.3	-1.1	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.5	-0.3	1.2
Alzheimer’s Disease (in father)	0.5	0.5	0.7	-0.6	0.8
Crohns Disease (2017)	0.5	1.2	1.3	1.1	1.0
Irritable Bowel Disease (IBD)	0.5	1.1	1.5	1.2	0.9
LDL Cholesterol	0.5	0.8	0.8	0.9	-0.9
Supplements: Zinc	0.5	0.5	0.7	0.8	0.6
Medication: Levothyroxine sodium	0.5	0.8	0.9	0.9	-0.9
Waist circumference	0.5	1.7	3.0	-1.7	-0.7
Nervous feelings	0.5	0.9	1.4	1.2	0.6
Qualifications: None of the above	0.5	1.0	1.9	0.2	1.4
Heart attack	0.5	0.6	0.8	-0.6	0.9
Qualifications: A levels/AS levels or equivalent	0.5	1.1	2.1	0.4	-1.4
Asthma	0.5	1.1	2.0	1.4	-0.4
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	1.8	-0.1	-1.3
Medication: Seretide 50 evohaler	0.5	0.5	1.1	0.0	-1.0
Hypertension (Self-reported)	0.5	1.4	2.6	1.6	-0.4
Handedness (chirality/laterality): Left-handed	0.5	0.6	0.8	-0.6	-0.9
Leg fat percentage (left)	0.5	1.8	3.5	-1.9	0.4
Irritability	0.5	0.8	0.9	-0.9	0.9
Alzheimer’s Disease (in mother)	0.4	0.4	0.7	-0.4	-0.8
Lupus	0.4	0.7	0.8	0.7	-0.9
Blood Eosinophil Count	0.4	3.2	6.0	-2.5	0.6
Heel T-Score	0.4	3.0	4.0	-2.0	1.4
Lung FVC	0.4	1.8	1.9	1.4	1.3
Sensitivity / hurt feelings	0.4	0.6	1.2	-0.3	1.1
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.7	-0.8	0.6
Relative age voice broke	0.4	0.7	0.8	0.7	-0.9
Hearing difficulty/problems with background noise	0.4	0.6	1.2	1.1	0.2
Forced vital capacity (FVC)	0.4	1.7	1.7	-1.3	-1.3
Allergy	0.4	0.8	1.6	-1.3	0.2
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	2.0	-1.4	-0.7
Breastfed as a baby	0.4	0.5	0.8	0.9	0.5
Peak expiratory flow (PEF)	0.4	0.9	1.8	-1.3	0.2
Pulse wave peak to peak time	0.4	0.5	0.7	-0.8	-0.5
Had major operations	0.4	0.5	0.9	0.1	1.0
Commuting to job workplace: Car/motor vehicle	0.4	0.4	0.9	0.1	0.9
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.3	1.2	-0.3
Asthma (self-reported)	0.4	0.8	1.4	1.2	-0.5
Illnesses of father: High blood pressure	0.4	0.5	0.8	0.5	-0.9
Unable to work because of sickness or disability	0.4	0.5	1.0	0.2	1.0
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.8	-0.5	0.9
Depressed Affect (Nagel 2018)	0.3	0.6	1.1	-1.1	-0.4
Breast Cancer	0.3	0.7	1.1	-1.0	-0.6
Hearing difficulty/problems: Yes	0.3	0.4	0.8	-0.9	0.4
Trunk fat percentage	0.3	1.4	2.7	-1.6	-0.2
Age when periods started (menarche)	0.3	0.8	1.7	1.3	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	1.1	-0.7	1.0
High blood pressure	0.3	0.9	1.5	1.2	-0.4
Multivitamins +/- minerals	0.3	0.4	0.7	-0.2	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	0.7	0.4	0.8
Hair/balding pattern: Pattern 2	0.3	0.4	0.8	-0.0	-0.9
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.6	0.8	0.4
Pulse wave Arterial Stiffness index	0.3	0.3	0.5	0.7	0.3
Length of working week for main job	0.3	0.3	0.5	-0.4	-0.7
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.4	0.5	0.7
Forced vital capacity (FVC), Best measure	0.3	1.0	1.7	-0.6	-1.3
Body fat percentage	0.3	1.3	2.6	-1.6	0.1
Wheeze or whistling in the chest in last year	0.3	0.5	0.7	0.9	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.6	-0.1	0.8
Health satisfaction	0.3	0.4	0.4	-0.6	-0.6
Heart disease (mother)	0.3	0.4	0.5	0.7	0.4
Age at last live birth	0.3	0.4	0.5	-0.7	-0.5
Smoking status: Previous	0.3	0.4	0.8	0.9	0.1
Medication: Aspirin	0.3	0.3	0.7	0.8	-0.0
Medication: Atorvastatin	0.3	0.4	0.7	-0.1	0.9
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.0	-1.0	0.6
Neuroticism (Nagel 2018)	0.2	0.5	0.9	-1.0	0.1
Worry (Nagel 2018)	0.2	0.4	0.7	0.8	-0.2
Alzheimer’s Disease (including proxy)	0.2	0.3	0.5	-0.7	-0.3
Ulcerative Colitis (UC)	0.2	0.4	0.5	0.7	0.5
Coronary Artery Disease (CAD)	0.2	0.2	0.3	-0.4	0.5
Fasting Glucose	0.2	0.2	0.3	0.2	-0.6
Blood Platelet Count	0.2	2.1	3.5	-1.9	0.9
Blood Red Count	0.2	1.8	2.4	-1.1	1.5
Hand grip strength (left)	0.2	0.4	0.7	-0.8	-0.4
Diabetes (mother)	0.2	0.2	0.4	0.3	-0.6
Maternal smoking around birth	0.2	0.3	0.6	-0.2	0.8
Stomach or abdominal pain in last month	0.2	0.2	0.2	-0.5	-0.5
Medication: Simvastatin	0.2	0.2	0.3	0.3	0.6
Father’s age at death	0.2	0.2	0.4	0.6	0.2
Mouth/teeth dental problems: Dentures	0.2	0.3	0.7	-0.1	0.8
Lung cancer (father)	0.2	0.3	0.5	0.7	0.2
Number of children fathered	0.2	0.3	0.5	0.7	0.3
Angina (self-reported)	0.2	0.2	0.4	0.6	0.0
Migraine (self-reported)	0.2	0.2	0.5	-0.7	-0.1
Alcohol intake frequency.	0.2	0.5	0.7	0.5	-0.8
Knee pain experienced in last month	0.2	0.3	0.6	-0.3	0.8
Friendships satisfaction	0.2	0.2	0.4	0.6	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.3	0.5	-0.4
Breast cancer (self-reported)	0.2	0.3	0.6	0.1	0.7
Osteoarthritis (self-reported)	0.2	0.2	0.4	-0.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	0.9	0.1	0.9
Miserableness	0.2	0.4	0.6	-0.5	0.8
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.0	-1.0	-0.2
HDL Cholesterol	0.1	0.1	0.1	-0.3	-0.4
Blood White Count	0.1	0.6	1.0	-1.0	-0.3
Smoking Status	0.1	0.3	0.6	-0.8	-0.2
Neuroticism	0.1	0.2	0.3	-0.6	-0.3
Hair Pigment	0.1	1.8	3.4	-1.8	0.4
Tanning	0.1	1.3	2.6	-1.6	0.0
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	-0.3	0.3
Angina	0.1	0.1	0.3	0.5	0.1
Pack years adult smoking proportion	0.1	0.1	0.1	-0.2	-0.4
Fed-up feelings	0.1	0.2	0.2	-0.5	-0.3
Taking other prescription medications	0.1	0.2	0.3	0.6	-0.3
Number of incorrect matches in round	0.1	0.1	0.2	0.5	0.3
Had other major operations	0.1	0.2	0.2	-0.3	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.3	-0.4	0.6
Neuroticism score	0.1	0.3	0.3	-0.5	0.6
Alcohol intake versus 10 years previously	0.1	0.1	0.2	0.4	0.2
Falls in the last year	0.1	0.1	0.1	-0.4	-0.2
Depression (self-reported)	0.1	0.2	0.2	0.4	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.5	-0.5	-0.7
Exposure to tobacco smoke at home	0.1	0.1	0.1	-0.3	-0.3
Tense / ‘highly strung’	0.1	0.2	0.4	0.2	-0.6
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.1	0.3	-0.4
Medication: Omeprazole	0.1	0.1	0.3	-0.1	-0.5
Suffer from ‘nerves’	0.1	0.1	0.2	-0.4	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.1	0.0	0.3
Mood swings	0.1	0.2	0.2	0.5	-0.3
Long-standing illness, disability or infirmity	0.1	0.1	0.2	-0.0	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.2	0.2	0.5
Qualifications: nursing, teaching	0.1	0.1	0.2	-0.2	-0.5
Back pain experienced in last month	0.1	0.2	0.2	-0.4	0.4
Commuting to job workplace: Cycle	0.1	0.1	0.2	-0.2	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.3	-0.1	0.5
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	-0.1	0.1
Cardiovascular Disease	0.0	0.1	0.1	0.4	-0.0
Respiratory disease	0.0	0.1	0.2	0.1	-0.4
Lung FEV1/FVC ratio	0.0	0.2	0.4	0.3	0.6
Number of treatments/medications taken	0.0	0.0	0.0	-0.2	0.1
Hand grip strength (right)	0.0	0.1	0.1	0.2	0.3
Past tobacco smoking	0.0	0.0	0.0	0.2	-0.0
Happiness	0.0	0.0	0.0	0.1	-0.1
Exposure to tobacco smoke outside home	0.0	0.0	0.0	-0.0	0.1
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.0	0.2	0.1
Average weekly red wine intake	0.0	0.1	0.1	0.1	0.3
Mineral and other dietary supplements	0.0	0.0	0.0	-0.2	0.1
Ever smoked	0.0	0.1	0.1	-0.3	0.1
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	-0.0	-0.1
Pack years of smoking	0.0	0.0	0.1	0.2	-0.2

Hub : Genes

ATP6V0E1

Models

Trait associations