Best TWAS P=2.29e-17 · Best GWAS P=4.49e-14 conditioned to 0.0563
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | RIOK1 | 0.14 | 0.02 | enet | 16 | 0.02 | 0.0120 | 5.7 | -6.8 | 1.5e-11 | -0.40 | 0.25 | 0.34 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DSP | 0.05 | 0.01 | blup | 113 | 0.02 | 0.0011 | 7.5 | 8.5 | 2.3e-17 | 0.74 | 0.00 | 0.98 | TRUE |