Hub : Genes

RIOK1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0540 0.0220 3.4e-03 0.039 0.020 0.046 0.027 0.031 1.2e-05 1.4e-03 2.6e-06 2.7e-04 8.9e-05
2 GTEx Adipose Subcutaneous 0.1070 0.0330 2.2e-04 0.046 NA 0.059 NA 0.056 1.1e-04 NA 1.4e-05 NA 2.1e-05
3 GTEx Artery Aorta 0.1810 0.0700 4.0e-03 0.010 NA 0.014 NA 0.014 8.6e-02 NA 5.1e-02 NA 5.5e-02
4 GTEx Artery Tibial 0.2149 0.0446 1.6e-08 0.166 NA 0.126 NA 0.152 5.0e-13 NA 4.5e-10 NA 5.3e-12
5 GTEx Brain Cortex 0.4310 0.0970 3.5e-05 0.007 NA 0.207 NA 0.146 2.0e-01 NA 2.2e-06 NA 7.8e-05
6 GTEx Brain Hippocampus 0.3860 0.1308 4.5e-03 -0.007 NA 0.010 NA 0.002 5.2e-01 NA 1.9e-01 NA 2.8e-01
7 GTEx Cells Transformed fibroblasts 0.1380 0.0490 1.7e-03 0.018 NA 0.020 NA 0.020 1.4e-02 NA 1.2e-02 NA 1.2e-02
8 GTEx Esophagus Mucosa 0.1300 0.0420 9.6e-04 0.053 NA 0.011 NA 0.027 1.9e-04 NA 6.0e-02 NA 5.8e-03
9 GTEx Skin Not Sun Exposed Suprapubic 0.1620 0.0550 1.7e-03 0.097 NA 0.041 NA 0.089 5.3e-06 NA 2.6e-03 NA 1.4e-05
10 GTEx Skin Sun Exposed Lower leg 0.1410 0.0340 1.3e-06 0.061 NA 0.075 NA 0.078 8.9e-06 NA 9.1e-07 NA 4.9e-07
11 GTEx Stomach 0.2310 0.0690 5.3e-04 0.061 NA 0.071 NA 0.050 7.3e-04 NA 2.6e-04 NA 1.9e-03
12 GTEx Testis 0.2300 0.0710 8.2e-04 0.179 NA 0.100 NA 0.169 2.2e-08 NA 3.4e-05 NA 6.0e-08
13 GTEx Whole Blood 0.0840 0.0300 1.1e-03 0.063 NA 0.051 NA 0.044 1.7e-06 NA 1.6e-05 NA 6.1e-05
14 METSIM Adipose 0.1296 0.0305 4.1e-12 0.102 0.103 0.103 0.103 0.099 4.7e-15 3.2e-15 3.8e-15 3.3e-15 1.2e-14
15 YFS Blood 0.0416 0.0111 1.0e-08 0.028 0.027 0.032 0.031 0.029 1.6e-09 2.4e-09 1.1e-10 1.3e-10 5.5e-10
16 TCGA Bladder Urothelial Carcinoma 0.0350 0.0210 2.9e-04 0.021 0.034 0.024 NA 0.022 6.8e-03 7.2e-04 3.9e-03 NA 5.2e-03
17 TCGA Brain Lower Grade Glioma 0.0435 0.0241 2.9e-05 0.039 0.047 0.043 NA 0.040 2.5e-05 4.1e-06 1.2e-05 NA 2.0e-05
18 TCGA Pancreatic Adenocarcinoma 0.0840 0.0460 3.5e-05 0.121 0.109 0.084 NA 0.082 9.2e-06 2.6e-05 2.2e-04 NA 2.5e-04
19 TCGA Prostate Adenocarcinoma 0.0543 0.0274 1.0e-08 0.075 0.082 0.078 NA 0.081 2.6e-08 6.1e-09 1.4e-08 NA 7.9e-09
20 TCGA Thyroid Carcinoma 0.0560 0.0260 1.2e-09 0.061 0.094 0.087 NA 0.088 1.4e-06 2.0e-09 7.9e-09 NA 7.3e-09
21 TCGA Uterine Corpus Endometrial Carcinoma 0.2660 0.1700 2.3e-04 0.184 0.109 0.117 NA 0.082 7.6e-06 5.8e-04 3.8e-04 NA 2.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bipolar Disorder (2018) 0.4 0.7 4.1 0.5 -0.9 -0.9 0.5 -1.4 -2.0 1.5 0.2 -0.6 -0.8 -0.9 0.1 -0.3 -0.4 -0.4 -0.6 -0.2 -0.3 -0.5 -0.2 -0.6
Bipolar Disorder or Schizophrenia 0.1 0.3 1.5 1.2 -0.0 -0.2 1.0 0.7 -1.1 0.3 0.5 -0.5 0.1 0.1 -0.6 0.2 -0.8 -0.0 -0.1 0.5 0.2 -0.1 0.4 -0.2
Depressed Affect (Nagel 2018) 0.2 0.5 4.6 0.6 -0.2 1.7 -0.5 0.3 -0.6 -2.1 -0.7 -0.4 -0.1 0.7 -0.4 -0.3 -0.2 -0.2 -0.0 -0.3 -0.5 -0.5 -0.1 -0.3
Depression (Nagel 2018) 0.5 0.7 4.1 0.4 -0.2 2.0 -0.3 1.0 1.6 -2.0 -0.4 -0.1 -0.6 0.9 -0.6 -0.7 0.4 0.0 0.1 0.2 -0.2 -0.4 0.1 -0.1
Intelligence (Savage-Jansen 2018) 0.2 0.6 1.6 -0.1 -0.8 -1.2 -1.0 -0.7 -0.5 0.2 -0.6 -1.0 -0.5 0.1 1.3 -0.4 -1.1 -0.2 -1.2 -0.4 -0.2 -0.5 -0.8 -0.9
Neuroticism (Nagel 2018) 0.4 0.9 7.1 0.5 -0.3 1.6 -0.9 0.5 1.4 -2.7 -0.9 -0.5 -0.6 1.3 -0.5 -0.8 -0.0 -0.7 -0.1 -0.5 -0.9 -0.9 -0.3 -0.7
Schizophrenia (2018) 0.3 0.6 4.1 1.2 0.8 0.5 0.9 2.0 -0.0 -0.9 0.5 -0.0 0.8 0.9 -0.8 0.6 -0.6 0.3 0.4 0.8 0.6 0.2 0.7 0.2
Schizophrenia vs Biploar Disorder 0.5 0.7 4.5 -0.3 0.2 0.5 0.2 0.3 1.9 -2.1 0.3 0.6 0.1 0.6 1.3 0.4 0.4 0.6 0.1 -0.0 0.7 1.0 0.1 1.0
Worry (Nagel 2018) 0.3 0.6 4.2 -0.4 -0.1 1.4 -0.6 -0.4 2.0 -1.3 -0.1 -0.4 -0.5 1.4 -0.5 -0.4 0.7 -0.3 0.1 -0.2 -0.4 -0.5 -0.1 -0.5
Alzheimer’s Disease (in mother) 1.1 1.3 4.1 0.9 1.0 1.3 1.1 -2.0 1.0 1.0 1.2 1.2 1.3 0.9 -0.9 1.1 1.8 0.5 0.8 1.1 1.1 1.0 1.0 0.8
Alzheimer’s Disease (in father) 0.4 0.5 2.5 0.7 0.6 -0.7 0.6 1.1 0.1 -0.5 0.4 -0.2 0.4 1.6 -1.4 0.6 -0.1 -0.1 0.6 0.7 0.1 -0.2 0.6 -0.1
Alzheimer’s Disease (including proxy) 0.9 1.3 3.7 1.1 1.1 1.0 1.2 -0.6 1.1 -0.0 1.2 1.0 0.8 1.7 -1.9 1.0 1.6 0.5 1.2 1.2 0.8 0.7 1.3 0.7
Crohns Disease (2017) 0.1 0.3 1.2 -0.4 -0.8 -0.4 -0.3 -1.1 -0.2 -0.5 -0.4 -1.1 -0.6 0.1 0.6 -0.4 0.1 -0.6 -0.8 -0.1 -0.2 -0.3 -0.2 -0.4
Irritable Bowel Disease (IBD) 0.2 0.4 2.5 -0.2 -0.6 0.1 -0.3 -1.0 -1.4 -1.6 -0.4 -0.8 -0.9 0.1 0.6 0.0 0.9 -0.5 -0.5 -0.4 -0.3 -0.2 -0.2 -0.1
Ulcerative Colitis (UC) 0.2 0.4 3.1 0.2 -0.1 0.2 -0.2 -0.5 -1.3 -1.8 -0.3 0.1 -0.8 -0.1 0.0 0.4 1.4 -0.0 0.2 -0.6 -0.3 0.1 0.1 0.5
Major Depression (MDD) 0.8 1.0 3.7 -1.4 -0.1 1.4 -0.5 1.9 1.5 -1.5 -0.5 -0.3 -0.6 0.2 0.5 -1.8 -0.9 -1.0 -0.5 -0.5 -0.6 -0.8 -0.6 -1.0
Reaction Time 0.1 0.3 1.8 0.5 -0.2 1.4 -0.3 -0.4 0.8 0.2 -0.2 -0.1 -0.2 0.9 -0.6 0.7 0.6 -0.1 0.3 0.0 -0.3 -0.3 0.0 -0.1
Verbal and Numeric Reasoning (VNR) 0.8 2.0 4.3 -0.5 -1.8 -1.8 -1.5 -0.8 -1.1 -0.3 -1.3 -1.7 -1.3 -0.5 1.6 -1.1 -2.1 -1.4 -1.8 -1.2 -1.3 -1.5 -1.6 -1.7
Breast Cancer 0.2 0.5 4.4 0.2 -0.2 -2.1 -0.7 -1.1 0.3 1.6 0.2 -0.0 0.2 0.8 0.1 0.1 0.1 -0.1 -0.2 -0.3 -0.4 -0.2 -0.4 -0.1
Ovarian Cancer 0.7 0.9 4.3 0.3 -0.9 -1.3 -0.5 2.1 -1.1 -0.6 -0.4 -1.0 -0.8 -0.5 0.5 -0.8 -1.9 -0.2 -0.7 -0.8 -0.9 -0.8 -0.6 -0.7
Prostate Cancer 1.1 1.6 3.7 1.7 0.9 0.5 1.4 -0.3 0.3 0.1 1.2 1.7 0.7 1.3 -1.5 0.9 1.6 1.3 1.9 1.0 1.1 1.4 1.5 1.9
Age at First Birth 0.3 0.5 2.0 -0.6 -0.7 -0.5 -1.2 0.4 -0.6 0.2 -1.4 -0.3 -0.7 -0.3 0.7 -0.9 -0.3 -0.7 -0.8 -0.6 -0.6 -0.6 -0.7 -0.7
Bipolar Disorder (2011) 0.6 0.6 1.5 0.6 0.7 0.2 0.8 1.2 0.2 0.2 0.9 0.6 0.5 -0.1 -0.7 1.0 -0.2 0.7 1.0 0.8 1.1 0.9 1.1 1.0
Body Mass Index (BMI) (2010) 0.4 0.6 4.2 -0.7 -0.2 1.1 -0.2 2.0 0.3 -1.3 -0.4 0.1 -0.7 -1.6 0.6 -0.2 -0.3 -0.4 -0.1 -0.7 -0.3 -0.0 -0.3 0.3
Coronary Artery Disease (CAD) 2.5 2.9 5.9 -1.1 -2.0 -0.2 -2.0 -1.8 -1.4 -1.4 -2.1 -1.1 -2.1 -1.3 0.9 -1.9 -1.1 -2.1 -1.4 -2.1 -2.4 -2.3 -1.9 -1.8
Crohns Disease (2012) 1.1 1.7 3.5 -0.9 -1.7 -0.8 -1.2 -1.3 -0.5 -0.0 -1.3 -1.7 -1.5 -1.2 1.7 -1.9 -0.6 -1.7 -1.5 -1.3 -1.3 -1.2 -1.3 -1.1
Mean Putamen Volume 0.9 1.0 6.9 -0.5 -1.0 -1.0 -0.6 0.9 -2.6 -0.5 -1.0 -0.8 -0.2 -0.7 1.0 -0.4 -2.3 -0.6 -0.8 -0.7 -0.6 -0.5 -0.7 -0.5
Fasting Glucose 1.7 2.0 6.2 2.0 1.2 2.1 1.4 -0.5 1.6 -0.2 0.8 0.9 0.8 1.4 -2.1 1.6 2.5 1.2 1.4 1.4 1.0 0.8 1.4 0.9
HbA1C 0.7 0.8 5.5 -0.3 -0.2 1.3 -0.4 2.1 2.3 -1.0 -0.8 -0.5 -0.3 -0.2 -0.6 -0.5 0.3 -1.0 0.3 -0.0 -0.2 -0.3 -0.0 0.0
HDL Cholesterol 0.1 0.2 1.3 -0.7 -0.1 0.2 -0.0 0.1 -0.0 -0.1 0.3 1.2 0.2 0.6 0.2 -0.8 0.0 -0.2 0.1 0.3 0.4 0.4 0.1 0.2
LDL Cholesterol 0.3 0.5 1.3 -0.5 -0.9 -0.2 -0.9 -0.1 -1.2 1.0 -0.9 -0.5 -0.5 0.5 0.3 -0.7 -0.9 -0.9 -0.6 -0.1 -0.4 -0.7 -0.5 -0.8
Lupus 0.4 0.6 1.6 -0.8 -0.7 1.3 -0.4 -0.6 0.7 0.1 0.1 -0.8 -0.4 -0.9 1.1 -0.4 0.1 -0.6 -0.8 -0.9 -0.9 -1.0 -1.0 -0.9
Neuroticism (2016) 0.2 0.3 1.4 -0.5 -0.1 1.2 -0.2 0.2 0.6 -1.2 -0.2 -0.0 0.1 -0.2 -0.2 -0.8 0.2 -0.7 -0.2 0.2 -0.2 -0.4 -0.3 -0.6
Primary Biliary Cirrhosis 1.0 1.5 5.8 -1.2 -0.8 0.1 -0.9 -2.2 -1.7 -2.4 -0.9 -1.0 -1.1 -1.0 0.7 -0.1 -0.9 -1.6 -0.6 -1.3 -1.3 -1.1 -1.0 -0.8
Rheumatoid Arthritis 0.9 1.2 4.9 1.0 1.2 0.3 0.7 0.1 0.3 2.2 0.9 1.0 1.5 0.5 -0.5 1.0 1.6 1.1 1.2 0.6 1.0 1.2 1.0 1.4
Schizophrenia (2014) 0.1 0.3 0.7 0.8 0.4 -0.2 0.7 0.6 -0.4 -0.7 0.2 0.6 0.4 0.4 -0.7 0.3 -0.5 0.5 0.7 0.5 0.6 0.5 0.8 0.8
Triglycerides 0.1 0.1 0.8 0.6 0.1 -0.6 -0.0 0.4 0.4 0.9 -0.1 0.0 0.2 0.1 -0.2 0.3 0.4 0.4 0.4 0.1 0.1 0.2 0.2 0.4
Type 2 Diabetes (T2D) (2012) 0.4 0.5 1.5 -0.9 -0.6 -0.4 -0.5 -0.7 1.2 -0.7 -0.9 -1.0 -0.5 0.7 0.4 0.0 1.1 -0.3 -0.7 -0.2 -0.4 -0.6 -0.5 -0.8
Ulcerative Colitis 0.6 0.9 3.0 -0.6 -1.1 0.1 -0.8 -1.4 -0.7 -1.3 -0.8 -0.6 -1.7 -0.9 1.1 -0.9 0.4 -1.0 -0.9 -1.2 -0.8 -0.7 -0.7 -0.4
Blood Eosinophil Count 0.1 0.7 9.4 0.4 0.1 -0.2 0.3 -3.1 -0.7 0.5 0.1 0.8 0.4 1.0 0.7 -0.1 1.3 0.1 -0.1 -0.1 0.2 0.6 0.0 0.5
Blood Platelet Count 0.2 2.4 31.7 -1.0 -1.0 0.8 -1.1 -5.6 -1.8 -0.2 -1.0 0.2 -1.4 -1.2 1.0 -1.9 0.6 -0.6 -0.8 -0.8 -0.5 -0.3 -0.6 -0.4
Blood Red Count 0.3 3.2 17.1 2.6 -0.2 -4.1 0.7 -3.7 -4.1 2.5 0.4 0.1 0.8 1.4 -0.7 0.6 0.5 0.1 0.4 0.7 0.4 0.4 0.7 0.5
Blood White Count 0.6 4.7 45.5 -1.1 -1.4 -1.4 -1.7 -6.7 -4.7 -0.2 -1.7 -0.3 -1.6 1.1 1.0 -0.7 0.3 -2.8 -1.2 -0.9 -0.9 -1.1 -1.1 -1.1
Heel T-Score 1.7 13.6 36.5 5.3 3.2 -1.6 3.8 2.7 2.4 2.6 4.0 2.5 4.8 1.6 -3.9 6.0 3.5 3.6 3.6 4.4 4.0 3.5 4.0 3.0
BMI 0.2 1.1 8.0 -0.6 -0.4 2.8 -0.3 1.8 1.3 0.5 -0.4 -1.1 -0.7 -0.9 -0.4 -0.9 -0.8 -1.2 -0.4 -0.2 -0.8 -1.2 -0.4 -1.2
Height 0.6 10.9 130.0 1.9 1.5 -5.5 0.5 1.5 0.6 3.0 -0.2 3.1 3.3 11.4 -0.3 -1.0 -1.8 2.7 0.7 2.3 2.6 1.8 1.3 0.6
Waist Hip Ratio (WHR) 0.9 4.2 15.0 -2.4 -1.6 1.2 -2.0 1.6 -3.9 -1.9 -1.9 -0.8 -2.6 -3.3 1.5 -2.2 -1.9 -1.5 -1.1 -2.6 -2.1 -1.4 -1.8 -0.8
Systolic Blood Pressure 0.3 1.5 8.9 -0.4 -1.3 -0.3 -0.9 -3.0 0.5 1.5 -1.0 -0.7 -1.2 1.3 0.6 -1.8 0.5 -1.2 -1.2 -1.0 -1.2 -1.3 -1.0 -1.4
Smoking Status 0.3 0.8 2.9 -0.9 -0.9 -1.7 -0.6 -1.0 -1.5 -1.1 -0.4 -0.4 -0.8 -0.1 1.1 0.3 -1.6 -0.7 -0.8 -0.4 -0.2 -0.3 -0.7 -0.5
Allergy or Eczema 0.2 0.6 1.6 0.4 1.1 0.7 0.8 0.9 0.6 -0.2 0.6 0.9 0.6 0.5 -0.5 1.3 0.7 0.3 0.8 1.1 1.2 1.0 0.9 0.7
Cardiovascular Disease 0.3 1.1 3.9 0.2 -0.4 1.7 -0.2 -2.0 0.8 1.7 -0.0 -0.6 -0.3 0.9 -0.4 -1.1 1.7 -1.4 -0.6 0.1 -0.6 -1.1 -0.5 -1.3
Hypothyroidism (self reported) 0.2 0.6 3.6 1.0 0.4 0.3 1.3 0.4 1.0 1.1 0.8 -0.5 0.3 1.9 -0.6 -0.2 0.9 0.1 0.0 0.5 0.1 -0.0 0.4 -0.0
Respiratory disease 0.4 0.8 2.7 1.0 1.0 -0.9 1.0 -1.1 1.5 -0.1 0.9 0.6 1.0 1.0 0.1 1.6 1.0 0.3 0.4 0.6 0.8 0.9 0.6 0.8
Type 2 Diabetes (T2D) (2018) 3.1 5.9 19.0 3.8 2.4 1.0 2.3 2.6 2.8 1.6 2.6 1.3 2.3 4.4 -2.5 2.6 2.5 1.8 1.9 2.5 2.0 1.7 2.1 1.7
Lung FEV1/FVC ratio 1.3 6.7 43.3 -1.1 -2.1 1.1 -2.3 2.6 -6.6 -2.2 -2.4 -2.2 -2.7 -3.1 0.4 -2.5 -2.8 -1.3 -1.6 -1.8 -2.6 -2.8 -2.0 -2.2
Lung FVC 2.2 11.3 38.7 1.2 4.1 2.4 3.5 0.8 3.2 0.9 4.3 2.2 3.5 0.2 -3.1 6.2 4.0 2.8 3.9 3.3 3.7 3.8 3.6 3.8
Neuroticism 0.4 0.8 4.8 -0.2 -0.8 1.0 -1.1 0.2 1.5 -2.2 -0.9 -0.6 -0.9 0.4 0.0 -0.6 -0.6 -0.8 -0.3 -0.9 -1.1 -1.0 -0.7 -0.7
Chronotype (morning person) 3.0 6.9 12.1 -1.5 -2.8 -2.0 -3.2 -1.0 -2.2 0.4 -3.3 -2.9 -2.8 -2.1 1.7 -2.6 -2.6 -3.2 -2.7 -3.0 -3.5 -3.3 -3.0 -2.9
Hair Pigment 0.0 1.4 3.8 1.7 0.8 -0.2 1.7 -0.7 0.1 -0.9 2.0 0.6 0.2 1.7 -0.6 1.3 1.9 0.9 1.0 0.9 1.2 1.3 1.2 1.4
Tanning 0.1 1.4 6.8 1.0 0.8 -2.6 0.3 1.0 -1.8 2.2 0.2 0.2 1.1 0.1 -0.4 2.1 -0.4 1.7 0.5 0.9 1.0 0.8 0.8 0.7
Hand grip strength (left) 0.3 0.9 7.1 0.1 0.7 -2.7 0.6 1.7 0.8 0.8 0.5 0.3 0.5 0.7 0.1 0.3 -1.4 1.1 0.1 0.8 1.0 0.7 0.7 0.3
Number of treatments/medications taken 0.5 0.9 5.5 0.0 0.5 1.7 0.5 -0.4 1.6 0.2 0.6 1.1 0.6 1.4 -0.2 1.0 2.3 -0.3 0.5 0.5 0.6 0.5 0.3 0.2
Average weekly spirits intake 1.6 2.0 6.4 1.4 1.7 0.8 0.6 -0.6 -1.1 2.5 0.8 1.4 1.9 2.0 -0.5 1.4 2.3 1.1 1.0 1.3 1.4 1.3 1.0 1.0
Sensitivity / hurt feelings 0.4 0.8 2.7 -0.2 -0.7 -1.1 -1.4 -0.5 1.1 -1.6 -1.2 -0.2 -0.8 0.1 0.4 -0.7 -0.9 -1.3 -0.3 -0.9 -0.9 -0.8 -0.8 -0.5
Frequency of depressed mood in last 2 weeks 0.5 0.7 5.0 -0.6 0.1 1.5 -0.5 1.8 2.2 -1.4 -0.4 -0.3 -0.5 0.2 -0.4 0.1 -0.3 -0.2 -0.1 0.2 -0.0 -0.3 -0.0 -0.4
Hearing difficulty/problems: Yes 2.7 4.2 6.7 -2.1 -2.0 -2.3 -2.0 -2.5 -1.4 0.1 -2.2 -2.4 -1.8 -2.2 1.3 -1.2 -1.4 -2.6 -2.1 -1.9 -2.4 -2.6 -2.3 -2.4
Relative age of first facial hair 0.6 1.2 6.6 -1.2 -1.0 1.4 -0.0 1.1 1.8 -2.6 -0.3 -0.9 -1.1 0.4 0.2 -1.2 -0.7 -1.1 -0.8 -0.8 -1.1 -1.0 -0.8 -0.8
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 2.1 -0.4 0.8 1.5 0.6 0.2 0.1 -0.0 0.9 -0.1 0.2 0.7 -0.6 1.2 0.9 0.1 0.6 0.6 0.7 0.6 0.6 0.6
Ever used hormone-replacement therapy (HRT) 0.4 0.5 2.0 -1.1 0.5 1.4 -0.1 0.8 1.2 -0.7 0.1 0.5 0.2 1.2 0.8 0.2 0.8 -0.2 0.0 -0.3 0.3 0.5 -0.1 0.3
Ever had hysterectomy (womb removed) 0.3 0.3 1.0 0.2 0.5 0.5 0.1 0.0 0.0 0.4 -0.0 0.3 1.0 0.2 0.1 0.6 0.6 0.5 0.4 0.6 1.0 0.9 0.6 0.9
Systolic blood pressure, automated reading 0.3 1.0 3.8 0.6 -0.8 -1.1 -0.2 -1.7 -1.4 1.9 -0.5 -1.2 -0.4 0.6 -0.2 -1.3 -0.6 -0.4 -1.0 -0.4 -1.0 -1.2 -0.5 -1.4
Eye problems/disorders: Diabetes related eye disease 1.2 1.3 3.8 1.9 1.1 1.1 1.1 1.6 0.6 -0.3 1.4 1.0 1.3 1.2 -1.9 0.6 0.5 0.8 1.3 1.3 0.8 0.7 1.2 0.8
Angina 0.6 0.8 2.6 0.6 0.7 0.8 1.3 -0.4 -0.6 -1.3 1.2 0.7 0.9 0.3 -0.1 1.4 1.6 0.8 0.6 0.5 0.7 1.0 0.7 1.1
Medication for hormone replacement therapy 0.6 0.7 2.9 -0.0 0.8 1.4 0.4 -0.2 1.7 0.2 0.6 1.1 0.8 0.6 0.2 0.8 0.8 0.7 0.7 0.4 1.0 1.1 0.6 0.9
Vitamin and mineral supplements 0.3 0.4 3.6 -0.2 0.4 0.3 -0.2 0.0 -1.9 -0.1 -0.6 0.8 0.3 -0.5 0.2 -0.4 0.3 0.4 0.5 -0.4 0.2 0.8 0.3 1.0
Supplements: Zinc 0.8 0.9 4.0 0.4 -0.7 -0.8 -0.5 -0.3 0.8 1.0 -0.5 -1.5 -0.4 0.5 -0.9 -1.3 -0.6 -1.3 -0.7 0.4 -0.7 -1.6 -0.5 -2.0
Medication: Co-codamol 0.2 0.2 0.9 -0.1 0.3 0.2 -0.3 -0.3 0.8 -0.9 -0.5 0.3 -0.1 0.9 -0.3 -0.6 0.6 -0.4 0.3 0.1 0.1 0.1 0.2 0.3
Medication: Metformin 0.8 1.1 6.0 1.6 0.8 1.2 1.0 1.8 1.3 -0.1 1.3 0.5 0.3 2.4 -1.2 0.4 0.9 0.5 0.7 0.9 0.6 0.4 0.6 0.3
Diabetes (father) 1.1 1.3 7.1 1.4 0.6 -0.4 0.6 -0.8 1.9 1.6 0.6 0.5 0.9 2.7 -1.6 0.9 1.4 0.8 0.8 1.3 0.7 0.5 0.8 0.2
Diabetes (mother) 0.2 0.3 1.6 0.6 0.3 0.8 -0.2 -0.4 0.8 -0.9 -0.1 0.3 0.1 1.3 -0.1 -0.7 0.8 0.1 0.2 -0.3 -0.0 0.3 0.2 0.5
Severe depression (siblings) 0.3 0.3 1.5 -0.7 -0.1 1.0 0.7 0.0 1.2 0.4 1.0 0.5 -0.3 -0.3 1.1 -0.3 0.4 0.1 -0.2 -0.2 0.4 0.5 -0.2 0.4
Pack years adult smoking proportion 0.5 0.7 4.2 0.1 0.4 1.7 0.1 2.1 2.0 -1.0 0.2 -0.2 -0.2 0.3 0.2 0.7 -0.3 0.3 0.1 0.4 0.6 0.5 0.5 0.5
Impedance of leg (right) 0.2 0.9 9.4 0.8 0.3 -3.1 -0.2 -1.4 -1.1 -0.5 0.2 0.4 0.4 -0.3 -0.3 0.2 -0.2 1.1 0.7 0.4 0.7 0.8 0.6 0.9
Leg fat-free mass (left) 0.2 1.2 14.4 -0.4 -0.2 1.0 -0.0 2.1 0.9 0.9 -0.5 0.1 0.1 3.8 0.3 -1.0 -1.0 -0.2 -0.6 0.2 0.0 -0.5 -0.3 -1.0
Trunk fat percentage 0.1 0.4 1.6 -0.6 -0.7 0.1 -0.3 0.2 -1.3 0.2 -0.3 -1.1 -0.6 0.2 0.6 -0.4 -1.0 -0.2 -0.7 -0.3 -0.3 -0.6 -0.5 -0.8
Hand grip strength (right) 0.3 0.8 4.8 -0.8 -0.3 -2.0 -0.0 0.7 -0.6 1.0 -0.3 -0.6 -0.1 0.7 1.7 -0.5 -2.2 -0.0 -1.1 -0.1 0.4 0.1 -0.5 -0.6
Townsend deprivation index at recruitment 0.5 0.7 3.0 -1.2 0.3 1.6 -0.1 1.3 1.7 -1.7 -0.1 0.1 0.0 1.3 0.2 0.9 0.4 -0.3 0.0 0.1 0.3 0.2 0.0 0.1
Current tobacco smoking 0.7 1.2 4.0 -1.2 -1.0 -0.6 -1.8 -0.6 0.7 -2.0 -1.3 -0.2 -1.4 -0.7 1.7 -0.3 -1.0 -1.0 -0.9 -1.4 -0.7 -0.4 -1.2 -0.3
Average weekly fortified wine intake 0.4 0.5 7.3 -0.2 0.3 -0.1 -0.4 0.0 -2.7 -1.1 -0.5 -0.4 0.3 0.8 -0.2 0.4 -0.2 -0.0 -0.1 0.2 0.0 -0.2 -0.1 -0.4
Maternal smoking around birth 0.5 0.7 1.9 0.7 0.7 -0.1 1.3 1.1 1.1 -1.1 1.0 0.8 0.3 0.6 -0.5 1.4 0.8 0.7 0.5 1.0 0.9 0.8 0.8 0.6
Fed-up feelings 0.2 0.4 3.9 0.8 0.5 0.9 0.4 0.6 0.2 -2.0 0.2 0.3 0.1 0.2 -1.0 0.4 0.5 0.4 0.6 0.3 -0.1 -0.1 0.4 0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 6.9 -0.9 -0.3 2.0 -0.3 0.8 1.7 -2.6 -0.2 -0.0 -0.9 0.8 -0.0 -0.2 -0.3 -0.2 -0.1 0.0 -0.2 -0.4 -0.2 -0.4
Relative age voice broke 0.7 1.1 5.5 0.4 1.0 1.1 0.8 1.5 0.2 -2.3 0.9 1.1 0.5 0.7 -1.5 0.6 0.0 1.0 1.5 0.5 0.4 0.8 1.1 1.2
Taking other prescription medications 0.2 0.3 2.4 -0.1 0.0 1.1 0.2 -0.4 1.6 -0.5 -0.0 -0.0 -0.2 0.1 0.1 0.1 0.9 -0.8 -0.5 0.0 -0.1 -0.3 -0.2 -0.5
Age when periods started (menarche) 0.2 0.5 5.4 -0.6 -0.2 0.7 0.6 -1.4 2.3 -0.8 0.4 -0.3 -0.0 -0.7 0.5 0.7 -0.0 -0.5 -0.2 -0.1 0.1 0.1 -0.0 0.1
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 2.1 -0.2 0.2 1.4 0.2 0.5 0.0 0.2 0.1 0.6 0.6 -0.0 -0.1 0.2 0.4 0.1 0.5 0.1 0.3 0.5 0.3 0.6
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.3 7.8 2.8 1.2 0.0 1.4 2.1 1.8 1.0 1.7 1.2 1.4 -0.2 -1.8 1.9 1.5 1.4 1.5 1.3 1.0 1.2 1.5 1.4
Tinnitus: Yes, but not now, but have in the past 0.8 0.8 3.5 -1.2 -0.7 0.3 -0.6 0.9 1.0 -0.5 -0.4 -0.8 -1.1 -1.9 1.6 -0.1 -0.2 -0.3 -1.1 -1.0 -0.7 -0.6 -1.1 -0.8
Qualifications: CSEs or equivalent 0.6 0.8 10.9 0.3 -0.5 1.0 -0.3 1.6 3.3 -0.2 -0.7 -0.0 -0.6 0.1 0.2 -1.0 -0.7 0.2 -0.2 -0.6 -0.5 -0.3 -0.2 -0.0
Serious illness, injury or assault to yourself 0.7 0.9 3.6 0.8 0.7 0.8 1.2 1.1 1.7 -0.1 1.1 0.8 1.0 1.9 -0.5 0.7 0.5 0.7 0.7 0.7 0.9 0.8 0.8 0.8
High blood pressure 0.5 1.3 9.4 0.7 0.2 1.3 0.6 -1.7 1.2 3.1 0.7 0.2 0.8 1.6 -0.5 -0.5 2.4 -0.5 -0.3 0.8 0.4 -0.1 0.2 -0.6
Hayfever, allergic rhinitis or eczema 0.2 0.4 1.8 -0.1 1.0 0.4 0.6 1.4 0.6 -0.0 0.4 0.8 0.3 0.1 -0.2 0.8 0.5 -0.1 0.5 0.7 0.9 0.7 0.6 0.4
Multivitamins +/- minerals 0.3 0.4 5.4 0.3 -0.0 -1.0 0.4 -0.3 2.3 0.3 0.6 0.2 0.1 0.7 -0.2 0.2 0.4 0.4 0.0 0.5 0.3 -0.0 0.1 -0.2
Stomach or abdominal pain in last month 0.8 1.0 5.8 -0.6 0.8 2.4 0.8 1.5 0.8 -1.9 0.8 0.7 0.1 0.8 -0.7 1.1 0.5 -0.4 0.9 0.7 0.7 0.6 0.7 0.6
Supplements: Glucosamine 0.2 0.3 2.6 1.0 0.3 -1.6 0.2 0.2 0.0 -0.1 0.3 0.6 0.3 -0.1 -0.8 0.2 -0.6 -0.3 0.5 -0.1 -0.3 -0.2 0.1 0.1
Diverticular disease/diverticulitis (self-reported) 1.7 2.1 4.3 1.0 1.4 2.1 1.6 1.6 -0.7 -0.5 1.4 1.3 1.3 1.3 -1.6 1.5 1.2 1.6 1.5 1.6 1.4 1.5 1.6 1.6
Medication: Atenolol 0.3 0.4 2.5 -0.4 0.0 1.6 -0.4 0.3 0.9 1.0 -0.5 0.1 0.1 1.5 -0.2 -0.5 1.1 -0.3 0.2 -0.3 -0.3 -0.2 -0.2 -0.2
Medication: Levothyroxine sodium 0.2 0.3 1.1 -0.5 -0.1 -0.4 0.2 0.1 0.0 -0.1 -0.0 -1.0 -0.6 0.7 -0.3 -0.4 -0.0 -1.0 -0.5 -0.3 -0.7 -0.9 -0.4 -0.9
Sitting height 0.3 2.2 16.0 -0.9 -0.4 -4.0 -1.1 0.5 -0.1 1.3 -1.6 1.3 0.4 3.5 1.3 -2.3 -1.3 0.2 -0.7 -0.2 0.2 -0.0 -0.6 -0.6
Chronic bronchitis/emphysema (father) 0.9 1.1 2.3 0.9 1.0 0.5 1.1 0.2 0.9 -1.1 1.1 1.5 1.2 0.4 -1.0 0.8 0.6 1.0 1.3 1.1 1.2 1.3 1.3 1.3
High blood pressure (mother) 0.4 0.6 1.5 -0.6 -0.7 0.7 -0.6 -0.3 -1.0 0.5 -0.9 -1.0 -0.4 1.2 0.3 -0.7 0.1 -0.9 -1.0 -0.4 -0.8 -0.9 -0.7 -1.1
Body mass index (BMI) 0.1 0.4 3.3 -0.3 -0.3 1.8 0.2 1.6 0.4 0.4 0.1 -0.7 -0.7 -0.3 -0.3 -0.2 -0.2 -0.5 -0.2 -0.1 -0.5 -0.8 -0.2 -0.6
Impedance of leg (left) 0.2 1.0 6.4 0.8 0.6 -2.5 -0.0 -1.7 -1.3 -0.5 0.4 0.6 0.6 -0.1 -0.1 0.7 0.0 1.3 0.8 0.6 1.1 1.2 0.8 1.2
Leg predicted mass (left) 0.2 1.3 13.5 -0.6 -0.4 0.9 -0.2 2.0 0.9 0.8 -0.6 0.0 -0.1 3.7 0.5 -1.1 -1.1 -0.4 -0.8 0.1 -0.2 -0.7 -0.5 -1.1
Trunk fat mass 0.1 0.4 2.3 -0.5 -0.5 0.3 -0.1 0.9 -0.7 0.6 -0.2 -0.7 -0.2 1.5 0.5 -0.6 -1.2 -0.1 -0.7 0.0 -0.1 -0.5 -0.4 -0.9
Waist circumference 0.2 0.9 2.0 -1.0 -0.9 0.4 -0.8 1.4 -0.4 0.5 -0.8 -0.9 -1.3 -0.2 0.9 -1.3 -1.0 -0.9 -1.0 -1.0 -1.0 -1.1 -1.0 -1.1
Number of incorrect matches in round 0.3 0.5 1.8 0.6 0.6 0.6 0.6 -0.0 0.6 0.9 0.6 0.3 0.9 0.4 -0.9 1.3 0.5 -0.1 0.8 1.1 0.9 0.6 0.9 0.4
Past tobacco smoking 0.5 0.9 8.2 0.8 0.5 2.3 0.5 1.0 2.9 -0.3 0.5 0.5 -0.1 -0.2 -0.5 -0.8 1.1 0.4 0.5 0.0 -0.0 0.2 0.2 0.3
Alcohol usually taken with meals 0.8 1.3 8.7 -0.8 -0.8 -2.4 -0.9 -2.2 -3.0 1.2 -0.8 -0.7 -0.7 0.0 0.3 -0.3 -0.3 -0.6 -0.6 -0.6 -0.7 -0.8 -0.7 -0.8
Nervous feelings 0.3 0.5 2.5 -0.5 -0.6 0.7 -0.7 -1.0 1.6 -0.4 -0.3 -0.8 -0.5 0.6 -0.0 -0.3 0.4 -1.1 -0.5 -0.4 -0.7 -0.9 -0.5 -0.8
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.7 4.3 0.7 0.7 2.0 0.0 2.1 1.0 -0.4 0.1 0.4 0.5 0.1 -1.2 0.8 0.4 0.2 0.8 0.7 0.4 0.1 0.7 0.2
Hearing difficulty/problems with background noise 1.5 2.3 5.6 -1.8 -1.5 -1.2 -1.6 -1.2 -0.9 -0.6 -1.7 -1.5 -1.8 -2.4 1.4 -0.9 -1.2 -2.0 -1.4 -1.8 -1.6 -1.6 -1.6 -1.3
Hair/balding pattern: Pattern 2 1.1 1.4 5.9 1.1 0.8 1.1 1.2 0.3 2.4 0.8 1.5 0.5 1.2 2.1 0.1 1.3 1.2 0.5 0.3 1.1 1.5 1.4 0.9 0.8
Had menopause 0.2 0.3 1.6 -0.0 0.1 0.1 -0.5 -1.3 -1.1 0.9 -0.2 -0.3 0.4 0.6 0.2 -0.0 0.7 -0.3 -0.4 -0.2 -0.2 -0.2 -0.3 -0.4
Had other major operations 0.3 0.3 2.7 -0.4 -0.3 -1.4 -0.0 0.5 -1.6 0.0 0.1 0.0 -0.1 -0.3 0.2 1.1 -0.6 -0.3 -0.3 -0.2 -0.2 0.0 -0.2 0.0
Forced vital capacity (FVC) 0.7 2.8 6.6 0.4 1.9 -0.4 1.6 0.6 2.5 0.6 1.8 1.8 1.9 2.6 -1.1 1.7 1.1 1.5 1.8 1.8 2.2 2.0 1.8 1.7
Heel bone mineral density (BMD) T-score, automated (right) 1.2 2.8 7.9 2.4 1.2 -0.2 1.8 2.8 2.6 0.8 1.9 1.6 1.6 0.2 -1.8 1.9 1.7 1.6 1.6 1.5 1.2 1.4 1.7 1.5
Ever unenthusiastic/disinterested for a whole week 0.1 0.1 0.6 -0.2 -0.0 -0.7 -0.1 -0.5 0.8 0.6 0.2 0.1 -0.0 -0.7 0.3 -0.1 -0.2 -0.5 -0.1 -0.3 -0.3 -0.2 -0.2 -0.0
Qualifications: None of the above 0.4 0.9 2.1 -1.4 -0.7 0.9 -1.5 -0.1 -0.3 -0.5 -1.4 -0.9 -1.0 -1.3 1.2 -0.0 -0.4 -0.9 -0.8 -1.3 -0.9 -0.7 -1.0 -0.7
Financial difficulties in last 2 years 1.6 2.1 9.5 0.8 1.3 1.0 1.5 0.3 3.1 -0.6 1.3 1.9 1.0 0.7 -1.0 0.8 1.2 1.5 1.5 1.3 1.7 1.8 1.7 2.0
Mouth/teeth dental problems 0.7 1.0 7.4 0.3 -0.8 -2.7 -1.1 -1.1 -1.4 -0.1 -1.0 -0.5 -0.4 -0.7 0.2 -0.9 -1.2 -0.9 -0.4 -1.1 -1.2 -0.8 -0.6 -0.2
Heart attack 3.1 4.0 9.2 -3.0 -2.1 0.7 -2.2 -1.1 -0.5 -2.9 -2.3 -2.0 -2.1 -1.3 2.3 -1.3 -1.0 -2.2 -2.1 -2.1 -2.0 -2.0 -2.3 -2.0
Allergy 0.6 1.3 4.0 -0.8 -1.6 -0.5 -1.5 -0.6 -1.4 0.1 -1.2 -1.1 -1.0 -0.8 0.8 -2.0 -1.2 -0.6 -1.1 -1.3 -1.4 -1.3 -1.2 -1.0
Pain all over the body in last month 4.3 4.6 7.3 2.0 2.5 2.1 2.4 0.6 1.3 -0.4 2.4 1.8 2.4 2.4 -2.7 1.9 2.5 2.5 2.4 2.6 2.2 1.9 2.4 1.8
Diabetes (self-reported) 2.7 4.2 12.6 2.7 2.1 0.4 2.1 2.0 1.5 0.9 2.5 1.6 2.0 3.5 -2.4 2.5 2.2 1.6 2.0 2.1 1.7 1.6 1.9 1.6
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 3.7 0.3 0.7 1.9 0.4 -0.4 -1.1 -1.3 0.6 0.1 0.2 -0.4 -0.3 1.3 1.0 -0.3 0.2 0.6 0.5 0.5 0.4 0.4
Medication: Ramipril 1.5 1.9 8.3 2.8 0.7 -0.3 0.7 0.7 -1.9 2.9 0.8 0.7 1.7 2.7 -0.9 0.5 2.0 0.6 0.4 1.1 0.7 0.3 0.7 0.0
Medication: Simvastatin 0.6 0.9 2.5 -1.3 -0.6 0.9 -0.3 -1.3 -1.6 0.4 -0.8 -0.9 -0.2 0.8 1.1 -0.4 0.3 -1.2 -1.3 -0.5 -0.6 -1.0 -1.0 -1.5
Fluid intelligence score 1.1 2.4 7.6 -1.4 -1.8 -1.6 -1.6 -0.6 -1.4 0.4 -1.6 -2.0 -1.0 -0.6 1.6 -1.2 -2.7 -1.5 -1.9 -1.2 -1.4 -1.6 -1.7 -1.9
Illnesses of siblings 0.3 0.4 1.9 -1.3 -0.3 0.1 -0.6 -1.0 -0.8 -0.7 -0.4 -0.4 -0.5 -1.4 0.1 0.0 -1.1 -0.4 -0.0 -0.6 -0.6 -0.5 -0.3 -0.2
Neuroticism score 0.4 0.9 4.1 -0.9 -0.8 1.0 -1.2 0.5 1.4 -2.0 -1.0 -0.5 -1.0 0.2 0.2 -0.8 -0.3 -0.9 -0.4 -1.0 -1.1 -0.9 -0.7 -0.7
Weight 0.2 0.8 8.6 -0.3 -0.1 0.6 0.1 1.8 0.4 0.9 -0.2 -0.1 0.0 2.9 0.1 -1.0 -1.1 -0.2 -0.5 0.3 0.0 -0.5 -0.2 -0.9
Impedance of arm (right) 0.7 3.4 13.8 -1.4 -1.9 -2.6 -1.5 -3.7 -3.4 -1.9 -1.2 -1.4 -1.7 -2.4 2.1 -1.1 -1.1 -0.7 -1.6 -1.8 -1.2 -0.8 -1.5 -0.6
Arm fat percentage (right) 0.2 0.7 1.9 -0.8 -0.8 1.4 -0.2 0.6 -0.7 -0.5 -0.2 -1.4 -1.2 -1.3 0.4 -0.5 -0.8 -0.6 -0.6 -0.7 -0.8 -0.9 -0.7 -0.8
Trunk fat-free mass 0.3 2.0 24.4 0.0 0.6 0.5 0.4 2.4 1.7 1.4 -0.1 1.1 1.0 4.9 -0.4 -0.7 -1.0 0.1 0.1 1.0 0.7 0.0 0.3 -0.5
Hip circumference 0.1 0.5 4.4 0.2 -0.1 -0.3 0.1 0.8 0.8 1.5 -0.2 -0.4 0.2 2.1 0.2 -0.5 -0.4 0.1 -0.5 0.4 0.2 -0.4 -0.1 -0.8
Time employed in main current job 0.6 0.7 7.6 -0.1 -0.3 -1.3 -0.9 -1.0 0.1 2.8 -0.7 0.1 -0.3 -0.4 -0.0 -1.0 -0.4 -0.5 0.2 -0.7 -0.4 -0.2 -0.1 0.1
Alcohol intake versus 10 years previously 0.5 0.8 2.0 -0.2 -0.8 -0.0 -0.5 0.8 0.6 0.8 -0.6 -1.4 -0.8 -1.2 0.4 -1.0 -0.7 -0.6 -1.0 -0.7 -1.1 -1.3 -1.0 -1.4
Father’s age at death 0.8 1.1 3.7 1.0 1.4 -0.5 0.9 -0.6 -0.7 1.9 1.0 0.6 1.4 0.5 -0.8 1.6 1.2 1.1 0.9 1.1 1.0 0.9 1.0 0.5
Worrier / anxious feelings 0.5 0.9 5.3 0.2 0.9 2.3 0.1 0.4 1.2 -0.3 0.4 1.2 0.9 1.5 -1.5 -0.1 1.1 0.1 1.0 0.5 0.2 0.4 0.8 0.5
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 2.6 0.3 -0.2 1.5 -0.2 1.0 1.6 -0.7 -0.1 -0.3 -0.5 1.1 -0.3 -0.7 -0.2 -0.8 -0.2 0.0 -0.4 -0.6 -0.2 -0.5
Falls in the last year 0.2 0.3 2.1 0.1 0.7 0.5 -0.1 0.4 0.0 0.3 0.3 0.4 0.4 1.3 -1.5 -0.3 0.5 -0.0 0.6 0.7 0.2 -0.2 0.4 -0.1
Hair/balding pattern: Pattern 3 0.7 1.0 10.9 -0.2 -0.1 0.9 -0.2 1.0 -3.3 2.2 -0.2 0.2 0.1 -1.1 -0.5 -1.2 -0.4 -0.3 0.1 -0.4 -0.6 -0.5 -0.2 -0.5
Number of live births 0.9 1.2 2.8 1.3 1.2 1.7 1.6 0.9 -0.0 -1.4 1.5 0.9 0.8 0.2 -0.7 1.4 1.1 0.7 1.0 0.9 1.0 1.2 1.1 1.2
Forced expiratory volume in 1-second (FEV1) 0.1 0.2 0.8 -0.7 0.3 -0.9 0.2 0.8 0.4 -0.1 0.4 0.3 0.2 0.6 -0.1 0.1 -0.7 0.6 0.4 0.5 0.6 0.3 0.3 0.2
Pulse rate 0.8 1.4 8.4 -2.9 0.1 0.1 0.1 0.4 2.1 -2.2 0.0 1.6 -0.6 -1.3 1.3 -1.1 0.5 0.5 0.5 -0.8 0.4 1.0 0.0 1.3
Happiness 0.6 0.7 2.8 -0.8 -0.8 -1.7 -0.8 0.4 0.0 -1.1 -1.0 -0.4 -1.0 -0.7 1.0 -0.2 -0.9 -0.5 -0.7 -1.0 -0.8 -0.6 -0.9 -0.5
Noisy workplace 0.4 0.5 4.7 -1.3 -0.1 2.2 -0.5 0.8 0.0 -1.0 -0.6 -0.1 -0.4 -0.6 0.5 -0.9 0.1 -0.4 -0.3 -0.6 -0.4 -0.3 -0.5 -0.3
Qualifications: A levels/AS levels or equivalent 0.1 0.3 1.6 0.0 0.2 -0.2 0.1 1.3 -0.7 0.2 0.4 0.5 0.0 0.9 0.3 0.3 -0.8 0.7 0.1 0.3 0.7 0.8 0.3 0.7
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 5.1 0.5 0.3 2.2 0.7 1.0 -0.9 -0.1 0.2 0.0 0.2 1.0 -0.4 0.3 -0.4 0.3 0.2 0.4 0.3 0.2 0.4 0.3
Mouth/teeth dental problems: Dentures 0.2 0.4 1.9 -1.0 -0.2 -0.6 0.0 1.0 0.2 0.9 0.3 -0.3 -0.1 -0.9 1.4 0.9 0.2 0.6 -0.5 -0.2 0.5 0.6 -0.4 0.1
Asthma 0.6 1.2 6.5 0.8 0.9 -0.1 1.4 -0.1 2.5 -1.3 1.3 0.5 0.8 0.6 -0.2 2.0 0.7 0.9 0.6 0.8 1.0 1.0 0.8 0.8
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.9 -1.2 -0.4 1.4 -0.4 -0.2 0.8 0.2 -0.5 0.5 -0.7 -0.5 -0.1 -0.2 0.3 -1.2 0.3 -0.5 -0.5 -0.4 -0.2 0.1
Medication: Cholesterol lowering 1.4 2.2 5.5 -2.2 -1.6 0.3 -1.6 -2.3 -0.5 -1.3 -1.6 -0.9 -1.6 -0.6 2.1 -1.1 -0.4 -2.0 -1.6 -1.7 -1.3 -1.3 -1.8 -1.4
Depression (self-reported) 0.3 0.3 2.9 -1.1 0.0 0.8 0.2 0.7 0.3 -1.7 -0.0 0.4 -0.1 0.2 0.4 -0.1 -0.0 0.4 -0.1 0.3 0.4 0.5 0.1 0.5
Medication: Lansoprazole 0.7 0.8 2.1 0.6 0.9 1.0 1.4 -0.5 -0.4 0.5 1.5 0.5 0.8 0.6 -0.8 0.9 1.0 0.6 0.6 1.2 1.1 0.7 1.0 0.4
Prospective memory result 0.2 0.3 3.4 -0.2 -0.2 0.5 -0.7 -0.2 0.3 1.9 -0.5 -0.2 0.2 0.1 0.4 -0.5 0.6 -0.5 -0.2 -0.5 -0.4 -0.3 -0.4 -0.1
Lung cancer (father) 0.3 0.4 3.2 -0.3 -0.2 1.8 0.4 0.9 0.1 0.7 0.1 0.3 -0.1 0.7 0.3 -1.0 -0.2 0.8 0.0 0.1 0.1 0.2 0.1 0.1
Illnesses of mother 1.2 1.5 6.6 -1.2 -1.3 -0.9 -1.2 -1.6 -0.7 -1.0 -0.7 -0.9 -1.9 -2.6 1.5 -0.5 -0.8 -0.6 -0.7 -1.7 -1.2 -0.7 -1.1 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.4 2.3 -0.1 0.8 -0.3 0.4 1.5 -0.2 0.8 0.6 0.7 0.7 0.6 -0.2 0.3 0.1 0.6 0.6 0.7 0.9 0.7 0.6 0.5
Pulse wave Arterial Stiffness index 0.5 0.6 1.6 -0.3 -0.7 -0.9 -0.8 0.8 -0.5 -0.2 -1.1 -0.3 -0.8 0.0 0.7 -0.8 -1.2 -1.3 -0.8 -0.8 -0.9 -0.7 -0.8 -0.7
Impedance of arm (left) 0.5 2.2 8.3 -1.0 -1.6 -2.5 -1.2 -2.9 -2.6 -1.5 -0.9 -1.5 -1.2 -1.7 1.8 -0.7 -1.1 -0.4 -1.3 -1.4 -0.9 -0.6 -1.2 -0.5
Arm fat mass (right) 0.1 0.5 1.4 -0.6 -0.7 0.9 -0.2 1.2 -0.1 0.3 -0.3 -1.0 -0.9 0.3 0.3 -0.7 -0.9 -0.5 -0.7 -0.4 -0.6 -0.9 -0.6 -1.0
Trunk predicted mass 0.3 2.0 24.6 0.2 0.6 0.6 0.5 2.3 1.7 1.4 -0.1 1.2 1.1 5.0 -0.5 -0.6 -0.8 0.2 0.1 1.1 0.8 0.1 0.4 -0.4
Standing height 0.4 3.6 50.4 -0.4 -0.1 -2.8 -0.4 0.2 -0.1 1.1 -0.9 1.1 1.1 7.1 1.3 -1.8 -2.2 0.5 -0.9 0.6 1.0 0.3 -0.3 -0.8
Length of working week for main job 0.8 0.9 2.4 -0.5 -0.8 -0.5 -0.6 -1.1 -1.1 1.5 -0.8 -1.4 -0.7 0.2 0.1 -0.2 -1.1 -1.2 -0.9 -0.6 -1.1 -1.5 -0.8 -1.3
Exposure to tobacco smoke at home 1.7 1.9 4.9 -1.4 -1.8 0.5 -1.4 -0.8 -0.3 -0.6 -1.4 -1.7 -1.4 -0.1 1.3 -2.2 -0.7 -1.8 -1.8 -1.1 -1.4 -1.7 -1.6 -1.8
Breastfed as a baby 1.8 2.2 6.1 2.5 1.3 2.2 1.9 -1.0 0.3 2.1 1.5 0.1 1.4 1.6 -2.0 1.3 1.5 0.7 1.1 2.0 1.3 0.6 1.6 0.3
Tense / ‘highly strung’ 0.4 0.7 3.4 -0.4 -0.6 0.3 -0.6 1.8 1.3 -1.9 -0.6 -0.6 -0.8 0.6 0.4 -0.7 -0.3 -0.4 -0.5 -0.6 -0.6 -0.6 -0.6 -0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.4 3.2 -1.8 0.0 1.2 -0.4 -0.2 -0.3 -1.4 -0.2 -0.2 -0.3 0.2 -0.1 0.2 0.1 -0.4 0.0 -0.0 -0.2 -0.2 -0.2 -0.3
Hair/balding pattern: Pattern 4 0.7 1.8 25.2 -0.2 -0.6 1.5 -0.4 0.2 5.0 -1.9 -0.5 -0.4 -1.0 1.5 0.2 -0.3 0.2 -0.5 -0.3 -0.7 -0.8 -0.7 -0.5 -0.3
Birth weight of first child 0.2 0.4 1.8 0.8 0.5 0.1 0.7 0.8 -0.2 0.9 0.5 0.1 0.8 0.6 -1.0 0.8 1.4 -0.2 0.6 0.6 0.1 0.3 0.5 0.4
Peak expiratory flow (PEF) 0.6 1.3 5.9 -1.1 -1.3 -1.1 -0.9 0.2 -2.4 -0.1 -0.8 -1.2 -1.3 -1.1 1.0 -1.1 -1.8 -0.6 -1.1 -0.7 -0.8 -1.1 -1.0 -1.1
Pulse wave reflection index 1.1 1.3 4.6 2.1 1.1 1.0 1.2 0.7 -0.7 1.8 1.1 0.8 1.1 0.6 -1.6 1.2 1.2 0.4 1.1 1.3 0.9 0.8 1.2 0.8
Ever highly irritable/argumentative for 2 days 1.2 1.5 6.2 -0.6 -1.1 -0.1 -1.3 0.2 0.4 0.3 -1.5 -0.8 -1.5 -2.5 0.6 -1.1 -0.8 -1.8 -1.0 -1.5 -1.7 -1.5 -1.3 -1.2
Loud music exposure frequency 0.4 0.4 2.5 0.3 0.3 0.0 0.3 1.6 1.2 1.2 0.3 0.8 0.9 0.2 -0.9 0.1 -0.5 0.0 0.6 0.5 0.3 0.2 0.4 0.2
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 1.8 -0.1 -0.6 -0.8 -0.5 0.9 0.6 1.4 -0.2 -0.9 -0.4 -0.5 0.6 -0.1 -1.2 -0.1 -0.7 -0.5 -0.6 -0.6 -0.7 -0.7
Mouth/teeth dental problems: Bleeding gums 0.5 0.7 5.0 0.6 0.8 2.2 0.7 0.1 0.6 -0.2 0.4 0.6 0.2 1.2 -1.3 0.1 0.3 0.8 0.7 0.9 0.6 0.3 0.9 0.1
Blood clot in the leg (DVT) 0.3 0.4 2.1 -0.4 0.0 1.5 0.8 -0.2 -0.9 -1.4 0.4 -0.0 -0.1 -0.7 0.2 -0.7 0.3 0.3 -0.2 0.1 -0.0 -0.0 -0.1 -0.1
Medication: Paracetamol 1.7 2.8 7.3 2.2 1.8 0.1 1.2 -0.2 2.6 0.3 1.5 2.5 1.2 1.5 -2.0 1.1 2.7 1.1 2.1 1.2 1.3 1.6 1.7 1.8
Headache pain in last month 0.2 0.4 1.5 -0.8 -0.6 -0.1 -0.9 -0.2 1.2 -0.6 -1.0 -0.0 -0.8 -0.0 0.4 -0.4 0.2 -0.8 -0.3 -0.7 -0.5 -0.3 -0.4 -0.1
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 5.0 -0.2 -0.4 -0.7 -0.2 1.4 -0.1 -0.4 -0.4 -1.0 -0.7 -0.9 0.0 -0.5 -2.2 0.3 -0.2 -0.4 -0.6 -0.4 -0.2 -0.2
Glaucoma (self-reported) 0.2 0.3 1.2 0.0 -0.7 0.2 0.1 -1.0 1.1 0.6 -0.0 -0.3 -0.5 -0.8 0.3 -0.6 0.4 -0.1 -0.5 -0.4 -0.6 -0.4 -0.4 -0.4
Gout (self-reported) 1.1 1.6 6.3 -1.7 -0.8 2.1 -0.4 -2.1 2.5 -0.3 -0.4 -1.6 -1.0 -0.8 1.3 -0.3 0.0 -0.8 -1.3 -0.8 -0.7 -1.0 -1.2 -1.3
Hypothyroidism/myxoedema (self-reported) 0.2 0.3 3.4 0.3 0.2 -0.2 0.8 -0.3 1.1 0.2 0.4 -0.5 -0.0 1.9 -0.4 -0.2 0.8 -0.4 -0.1 0.1 -0.2 -0.3 0.1 -0.2
Medication: Amlodipine 0.9 1.3 11.1 0.4 1.1 0.8 0.8 -0.3 0.4 2.2 0.9 0.7 1.4 0.5 -0.8 1.1 3.3 0.6 0.5 1.0 1.0 0.6 0.8 0.4
Medication: Ventolin 100micrograms inhaler 1.4 1.8 3.8 1.0 1.3 0.8 1.7 -1.0 1.9 0.3 1.6 1.4 1.4 0.2 -1.2 1.6 1.5 1.4 1.5 1.4 1.4 1.5 1.4 1.5
Birth weight 0.3 0.7 5.1 -0.1 -0.1 -1.2 -0.8 0.2 -2.3 0.3 -0.9 -1.3 -0.4 0.6 -0.2 -0.5 0.2 -1.1 -0.5 0.0 -0.5 -0.8 -0.4 -1.0
Chronic bronchitis/emphysema (mother) 1.1 1.2 3.6 -0.1 1.1 -0.3 0.9 1.1 1.0 -0.6 1.1 1.9 1.2 0.8 -1.0 1.0 0.4 1.0 1.2 1.4 1.5 1.4 1.3 1.3
High blood pressure (siblings) 0.3 0.4 3.5 0.6 0.3 -0.3 0.1 1.0 0.8 1.9 0.0 0.4 0.7 0.5 -0.1 0.0 0.8 0.3 -0.0 0.6 0.6 0.4 0.2 -0.0
Forced vital capacity (FVC), Best measure 0.4 1.3 3.3 0.1 1.4 -0.5 0.9 0.5 1.6 1.1 1.2 1.2 1.5 1.8 -0.4 1.2 1.1 0.7 1.0 1.2 1.6 1.4 1.1 1.1
Body fat percentage 0.0 0.2 0.9 -0.4 -0.4 0.4 0.0 0.6 -1.0 0.2 0.1 -0.9 -0.4 -0.0 0.2 -0.1 -0.7 0.0 -0.3 -0.0 -0.2 -0.4 -0.2 -0.5
Leg fat percentage (right) 0.1 0.4 2.5 0.5 0.4 0.4 0.7 1.6 -0.7 0.3 0.8 -0.1 0.2 -0.0 -1.0 0.4 -0.1 0.6 0.7 0.5 0.3 0.2 0.6 0.3
Arm fat-free mass (right) 0.5 2.4 27.1 0.6 0.7 0.6 0.4 3.0 1.9 2.2 -0.1 0.9 1.2 5.2 -0.6 -0.3 -0.7 0.3 0.2 1.2 0.8 0.1 0.4 -0.5
Exposure to tobacco smoke outside home 0.4 0.5 3.7 -0.3 -0.5 1.3 -0.1 -0.5 -0.9 -1.9 -0.4 -0.8 -0.9 -0.6 -0.4 -0.3 -0.0 -0.7 -0.0 -0.3 -0.7 -0.7 -0.2 -0.2
Comparative body size at age 10 1.0 2.8 6.2 1.5 2.1 0.3 1.5 2.5 -0.8 1.3 1.9 1.7 1.9 0.3 -1.7 2.2 1.4 1.5 1.8 1.8 1.9 1.8 1.9 1.6
Number of full brothers 2.1 2.7 5.9 -0.8 -1.6 -0.6 -1.8 0.0 0.9 -0.2 -2.0 -2.4 -1.6 -2.0 1.6 -1.4 -1.9 -2.0 -2.1 -1.4 -1.5 -1.9 -1.8 -2.2
Worry too long after embarrassment 0.6 1.0 5.4 -0.2 -1.1 0.5 -1.1 0.7 2.3 -1.3 -1.1 -1.0 -1.1 -0.6 -0.1 -0.8 -0.7 -0.8 -0.6 -0.7 -1.1 -1.2 -0.6 -0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 1.3 -0.5 -0.4 1.1 0.5 0.8 0.5 -0.8 0.8 0.2 -0.2 0.6 0.5 -0.0 0.3 0.5 -0.3 -0.1 -0.0 0.2 -0.1 0.1
Wheeze or whistling in the chest in last year 0.8 1.3 3.2 1.4 1.3 1.5 1.6 -0.9 1.8 -0.8 1.8 0.6 0.8 0.9 -0.3 1.3 1.5 0.5 0.5 1.3 1.3 1.0 0.9 0.6
Number of children fathered 2.1 2.4 6.6 -1.3 -1.4 -2.0 -1.2 -2.1 -2.1 1.0 -1.5 -1.9 -0.8 -0.8 0.8 -0.2 -1.3 -2.6 -1.7 -0.8 -1.4 -1.8 -1.4 -1.9
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 1.6 0.6 0.2 0.5 -0.2 -0.5 1.3 -0.1 -0.3 0.3 0.4 0.3 0.2 1.0 0.9 -0.2 -0.1 0.3 0.4 0.3 0.1 0.0
Age at first live birth 0.6 1.0 4.6 -0.7 -0.8 -1.2 -0.8 -1.2 -1.2 2.1 -0.8 -1.1 0.1 0.3 0.7 -1.1 -1.6 -0.3 -1.2 0.1 -0.2 -0.8 -0.6 -1.4
Pulse wave peak to peak time 0.6 0.7 2.0 0.5 0.7 0.7 0.8 -0.8 0.3 0.4 1.0 0.3 1.0 0.6 -0.7 0.8 1.1 1.4 0.8 0.9 1.0 0.8 0.9 0.7
Health satisfaction 0.4 0.6 5.1 0.6 -0.0 0.2 -0.0 1.7 2.3 -0.0 -0.3 0.5 0.1 1.4 -0.4 -1.1 0.0 0.2 0.0 0.1 -0.2 -0.2 0.1 -0.2
Shortness of breath walking on level ground 0.5 0.5 5.2 -0.9 -0.3 0.1 -0.7 -1.0 2.3 0.3 -0.6 0.1 -0.4 1.0 0.6 -0.6 0.1 -0.3 -0.5 -0.3 -0.3 -0.3 -0.6 -0.7
Qualifications: College or University degree 0.2 0.6 5.1 0.1 -0.2 -2.2 0.5 0.7 -0.3 1.9 0.7 -0.1 0.3 1.0 0.1 0.1 -0.5 0.3 -0.1 0.7 0.4 0.1 0.1 -0.2
Eye problems/disorders: None of the above 0.3 0.3 2.4 -0.3 0.4 0.7 0.1 -0.8 -0.1 -1.6 0.2 0.4 -0.4 -0.3 0.7 0.3 0.9 0.2 0.1 -0.2 0.4 0.6 0.2 0.6
Mouth/teeth dental problems: Loose teeth 1.3 1.5 3.5 -1.2 -1.3 -0.6 -1.2 -0.4 0.8 -1.1 -1.4 -1.0 -1.8 -0.6 0.8 -1.9 -0.9 -1.3 -1.1 -1.2 -1.5 -1.6 -1.4 -1.4
Emphysema/chronic bronchitis 0.7 0.8 2.1 -1.5 -0.8 -0.1 -0.6 0.4 0.5 -1.1 -0.7 -0.7 -0.8 -0.3 1.4 -0.8 -1.3 -1.0 -1.3 -0.6 -0.5 -0.7 -1.0 -1.0
Medication for pain relief, constipation, heartburn 0.5 0.8 2.6 -0.9 -0.8 -0.5 -0.5 0.3 -1.6 -1.1 -0.7 -1.3 -0.6 -1.2 1.2 -0.8 -1.6 0.5 -1.1 -0.6 -0.5 -0.5 -0.6 -0.6
Neck or shoulder pain in last month 0.6 0.8 1.8 1.0 0.6 1.3 1.4 0.3 0.2 -0.8 1.3 0.8 0.6 0.8 -0.2 1.3 0.8 0.2 0.6 1.0 1.2 1.2 1.0 1.0
Medication: Blood pressure 0.7 1.2 7.8 1.3 0.8 -0.2 0.4 -1.7 -0.2 1.2 0.8 1.3 1.3 1.4 -0.8 0.8 2.8 0.3 0.7 0.9 0.9 0.8 0.7 0.8
Angina (self-reported) 0.6 0.8 2.1 0.6 0.7 0.8 1.3 -0.5 -1.0 -1.4 1.2 0.7 0.8 0.3 -0.1 1.3 1.5 0.7 0.7 0.4 0.6 1.0 0.7 1.1
Migraine (self-reported) 1.3 1.7 9.2 -2.1 -1.4 0.2 -1.2 -1.2 -0.9 -3.0 -1.0 -0.4 -1.7 -1.5 1.4 -0.4 -1.0 -1.1 -0.7 -1.4 -0.8 -0.7 -1.1 -0.5
Medication: Ibuprofen 0.3 0.3 1.5 -1.1 -0.4 1.2 -0.6 0.4 0.9 0.3 -0.7 0.4 -0.3 -0.2 0.2 0.1 0.1 -0.9 0.3 -0.6 -0.4 -0.3 -0.3 0.2
Medication: Allopurinol 0.4 0.6 4.4 -0.6 0.2 1.0 0.5 -2.1 1.9 -0.5 0.5 -0.4 -0.1 0.2 0.4 0.8 0.9 0.0 -0.2 0.0 0.2 0.1 -0.1 -0.0
Medication: Omeprazole 0.4 0.5 4.5 0.0 0.1 0.5 0.4 1.3 2.1 -0.3 0.2 -0.3 -0.1 -1.0 0.3 -0.1 -1.1 -0.4 -0.4 0.3 0.2 -0.1 -0.1 -0.3
Medication: Seretide 50 evohaler 0.5 0.6 3.3 -0.1 0.4 1.4 0.4 -0.4 1.8 0.0 0.4 0.8 0.6 0.3 0.4 1.6 0.5 0.3 0.4 0.3 0.7 0.9 0.3 0.7
Mean time to correctly identify matches 0.2 0.3 1.6 0.6 0.1 1.0 -0.1 -1.0 0.0 0.5 -0.0 0.0 0.5 0.5 -0.5 1.3 1.0 -0.2 0.2 0.4 0.1 -0.1 0.1 -0.2
Heart disease (mother) 0.2 0.3 1.9 0.5 0.2 0.5 -0.1 1.0 -1.0 -0.1 -0.3 0.4 0.3 1.4 -0.2 -0.3 0.7 -0.1 -0.2 0.1 0.0 -0.0 -0.1 -0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.8 2.1 0.7 1.0 -1.1 0.3 -0.4 1.4 -0.7 0.5 1.0 0.9 0.5 -1.3 1.4 0.9 0.3 1.1 0.7 0.5 0.5 0.8 1.0
Whole body fat mass 0.1 0.4 1.6 -0.5 -0.4 0.5 -0.0 1.2 -0.5 0.6 -0.1 -0.8 -0.2 1.3 0.3 -0.3 -1.0 -0.2 -0.6 0.1 -0.1 -0.6 -0.3 -0.9
Leg fat mass (right) 0.1 0.3 2.8 -0.1 -0.0 0.7 0.4 1.7 -0.4 0.5 0.3 -0.3 -0.1 1.1 -0.2 -0.1 -0.7 0.1 -0.0 0.3 0.1 -0.2 0.1 -0.4
Arm predicted mass (right) 0.4 2.2 26.7 0.4 0.6 0.9 0.4 2.8 1.8 1.6 -0.1 1.0 1.0 5.2 -0.4 -0.5 -0.6 0.3 0.1 1.0 0.7 0.2 0.4 -0.4
Pulse rate, automated reading 1.4 4.5 45.6 -3.3 1.4 0.9 1.3 1.6 2.2 -6.8 1.0 2.0 -0.2 -0.4 0.8 1.1 0.4 1.2 1.4 0.9 2.2 2.0 1.2 2.0
Alcohol intake frequency. 0.3 0.8 7.1 0.3 -0.3 2.7 -0.0 1.6 1.3 -0.1 -0.2 -0.7 -0.3 1.3 -0.2 -0.7 0.7 -0.2 -0.5 0.1 -0.3 -0.6 -0.2 -0.8
Comparative height size at age 10 0.3 1.8 23.6 -0.2 0.1 -2.0 -0.7 0.5 -0.0 0.2 -0.7 1.1 0.3 4.9 1.3 -0.9 -1.6 0.4 -0.6 0.3 0.9 0.4 -0.2 -0.4
Number of full sisters 1.0 1.3 3.0 1.7 1.0 1.6 1.1 0.8 -1.0 0.6 1.3 1.4 0.8 0.2 -0.6 1.1 1.7 0.5 1.2 0.5 0.9 1.4 1.1 1.5
Suffer from ‘nerves’ 0.1 0.2 0.8 -0.6 -0.1 0.7 -0.2 -0.1 0.2 0.4 0.1 -0.4 -0.2 0.9 -0.2 -0.0 0.6 -0.6 -0.2 0.3 0.0 -0.3 0.1 -0.7
Overall health rating 0.6 1.3 5.2 0.7 0.4 2.2 0.7 2.1 2.3 -0.9 0.6 1.2 0.3 1.8 -0.6 -0.2 1.8 -0.2 0.4 0.7 0.4 0.3 0.4 0.2
Chest pain or discomfort 0.3 0.4 1.6 -0.2 0.1 1.0 -0.2 0.3 1.3 0.3 -0.1 -0.4 -0.1 0.5 1.0 -0.1 -1.1 -1.1 -0.8 0.1 0.3 -0.3 -0.4 -0.9
Had major operations 0.4 0.5 0.7 0.8 0.6 0.5 0.7 -0.9 0.4 0.8 0.8 0.8 0.2 -0.5 -0.6 0.7 0.8 0.7 0.7 0.8 0.9 0.8 0.7 0.6
Age at last live birth 1.6 2.3 5.8 -2.0 -1.5 0.3 -1.8 -0.8 -1.0 -0.4 -1.6 -1.6 -1.3 -0.5 2.2 -1.8 -2.4 -1.2 -2.0 -1.1 -1.0 -1.3 -1.7 -1.8
Family relationship satisfaction 0.6 0.7 3.3 -0.2 0.4 0.7 0.8 1.0 1.8 -1.4 0.9 1.2 0.5 1.2 -0.3 -0.2 -0.2 0.9 0.4 0.6 0.7 0.7 0.5 0.6
Leg pain on walking 0.7 0.9 4.5 0.2 1.0 2.1 0.4 1.3 1.1 2.0 0.3 0.1 0.8 0.7 -0.7 0.7 1.1 0.5 0.4 0.9 0.7 0.2 0.5 -0.2
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 4.6 0.0 -0.1 2.1 -0.3 -0.7 -0.7 -0.5 -0.1 -0.4 -0.3 -0.2 0.5 0.1 0.7 -1.1 -0.7 0.2 -0.0 -0.5 -0.3 -0.9
Commuting to job workplace: Car/motor vehicle 0.7 0.8 1.5 1.2 1.1 0.1 1.2 0.7 0.1 -0.0 1.1 0.9 1.1 -0.5 -0.7 0.8 0.9 1.0 0.9 1.0 1.0 1.0 1.0 0.7
Illness, injury, bereavement, stress in last 2 years 1.4 1.7 4.1 -2.0 -1.2 -1.7 -2.0 -0.3 -0.7 -0.3 -1.7 -1.2 -1.2 -0.9 1.3 -0.8 -1.0 -1.2 -1.3 -1.3 -1.2 -1.3 -1.6 -1.6
Medication: Aspirin 1.0 1.3 8.2 0.9 0.7 1.6 1.1 -0.3 0.6 1.5 1.2 0.9 1.3 2.9 -0.6 0.8 1.8 -0.0 0.6 1.2 1.1 0.8 0.7 0.4
Supplements: Vitamin C 0.2 0.3 1.1 0.5 0.5 -0.2 0.3 0.2 0.5 0.4 0.8 0.2 0.2 0.7 -1.0 0.8 0.7 -0.2 0.3 0.9 0.4 -0.2 0.3 -0.3
Knee pain experienced in last month 0.9 1.3 3.3 -0.9 -1.2 1.3 -1.1 0.3 1.7 -0.3 -1.1 -0.5 -1.7 -0.9 0.6 -1.8 -0.5 -1.6 -0.8 -1.4 -1.4 -1.3 -1.1 -1.0
Hypertension (Self-reported) 0.4 1.1 7.1 0.6 0.0 1.0 0.6 -1.9 0.9 2.7 0.8 0.2 0.6 1.0 -0.4 -0.6 2.5 -0.6 -0.3 0.5 0.1 -0.2 0.1 -0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 1.9 0.1 0.4 0.1 0.3 0.7 0.6 -1.1 0.5 1.4 -0.0 0.2 -0.2 -0.7 0.0 -0.1 0.5 0.2 0.5 0.7 0.5 0.8
Illnesses of father: Heart disease 0.3 0.4 2.1 -0.5 -0.5 -0.3 -0.5 1.1 0.5 -0.5 -0.1 0.3 -1.1 0.0 0.5 -1.4 0.8 0.2 -0.2 -0.7 -0.3 -0.0 -0.3 0.2
Illnesses of siblings: Diabetes 0.4 0.5 3.6 0.1 -0.0 -0.1 0.1 1.1 -0.0 1.0 0.3 -1.0 0.1 1.9 0.8 -0.6 0.5 -0.2 -1.1 0.2 0.1 -0.2 -0.5 -0.9
Smoking status: Previous 0.4 0.6 6.8 -0.4 0.0 -1.5 0.5 -0.1 -2.6 0.5 0.3 -0.3 0.7 0.3 -0.1 0.7 -0.9 -0.1 -0.3 0.7 0.5 0.1 0.3 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.1 8.8 0.4 0.9 0.7 1.0 0.6 1.4 -1.1 0.7 1.3 0.8 3.0 -0.1 0.4 0.3 1.0 0.6 0.6 0.9 1.1 0.8 1.1
Whole body fat-free mass 0.3 1.8 22.7 -0.1 0.4 0.8 0.3 2.4 1.5 1.2 -0.2 0.8 0.7 4.8 -0.2 -0.7 -1.0 0.0 -0.2 0.8 0.5 -0.1 0.1 -0.7
Leg fat-free mass (right) 0.2 1.2 14.8 -0.4 -0.1 1.2 0.1 1.9 1.1 0.8 -0.3 0.4 0.1 3.9 0.4 -0.8 -0.8 -0.1 -0.5 0.3 0.2 -0.3 -0.2 -0.7
Arm fat percentage (left) 0.1 0.6 2.1 -0.6 -0.7 1.1 -0.2 1.1 -0.4 -0.3 -0.1 -1.5 -1.0 -1.0 0.3 -0.2 -0.8 -0.5 -0.6 -0.6 -0.7 -0.9 -0.6 -0.8
Average weekly red wine intake 0.5 0.8 2.0 0.1 1.2 0.4 0.8 1.3 -0.6 -0.7 0.4 0.4 0.7 1.2 -1.4 0.9 0.6 0.9 1.1 1.0 0.8 0.6 1.0 0.7
Handedness (chirality/laterality): Left-handed 0.3 0.4 1.7 0.1 0.2 -0.7 -0.9 0.3 -1.3 1.1 -0.5 -0.2 0.1 -0.7 -0.7 0.0 -0.8 -0.2 0.0 0.1 -0.3 -0.7 -0.1 -0.8
Mood swings 0.3 0.6 4.2 -0.6 -0.2 1.6 -0.9 1.4 0.6 -2.0 -0.9 0.5 -0.4 -0.1 0.0 -0.6 -0.3 -0.8 -0.1 -0.3 -0.3 -0.3 -0.3 -0.3
Loneliness, isolation 0.7 1.0 4.1 -1.2 -0.8 0.6 -1.0 0.9 -1.2 -2.0 -1.0 -0.9 -0.7 0.2 0.4 -0.5 -1.6 -0.9 -0.8 -0.6 -0.9 -1.1 -0.8 -1.0
Long-standing illness, disability or infirmity 1.1 1.7 4.4 0.6 1.4 2.1 1.3 1.4 1.9 -0.7 1.5 1.3 1.2 1.8 -0.8 1.1 1.7 0.6 1.1 1.1 1.3 1.3 1.1 1.1
Ever had bowel cancer screening 0.8 0.9 3.3 -1.0 -0.9 0.3 -0.9 -1.8 -0.5 -0.4 -0.7 -0.9 -0.9 -1.2 0.6 -1.1 -0.4 -1.4 -1.1 -0.7 -1.0 -1.1 -0.9 -1.2
Diabetes diagnosed by doctor 3.6 5.9 17.2 3.2 2.5 1.5 2.5 2.3 1.6 1.8 2.8 1.8 2.3 4.2 -3.1 2.8 2.8 1.5 2.4 2.7 2.1 1.7 2.3 1.7
Ever had stillbirth, spontaneous miscarriage or termination 1.8 2.0 4.0 0.8 1.6 0.6 1.6 -1.0 0.9 0.6 1.7 1.9 1.7 1.5 -0.3 0.7 1.6 1.5 1.2 1.4 2.0 1.9 1.5 1.5
Friendships satisfaction 0.2 0.3 1.8 0.7 0.2 0.8 0.1 1.4 -0.6 -0.2 -0.1 0.0 0.2 0.5 -0.7 0.4 -1.1 -0.5 0.2 0.6 0.2 -0.1 0.2 -0.4
Qualifications: nursing, teaching 0.3 0.4 4.7 0.4 0.2 -1.2 -0.6 0.4 0.4 2.2 -0.0 -0.4 0.6 0.1 0.1 0.5 -0.4 -0.1 -0.3 0.4 0.4 0.0 -0.0 -0.3
Commuting to job workplace: Walk 4.4 4.8 12.0 -3.0 -2.5 0.4 -2.0 -0.7 -0.9 -1.2 -2.0 -2.3 -2.3 -1.2 1.7 -2.3 -3.5 -2.5 -2.4 -2.2 -2.5 -2.7 -2.4 -2.6
Eye problems/disorders: Cataract 0.3 0.3 2.8 0.2 0.2 -1.7 0.0 0.3 0.5 0.8 0.1 0.2 0.5 0.0 -0.2 0.7 -0.5 0.6 0.1 0.6 0.7 0.7 0.4 0.4
Mouth/teeth dental problems: Mouth ulcers 2.6 4.1 16.8 0.4 1.9 4.1 2.2 0.9 4.1 -0.1 2.1 2.0 1.3 1.9 -1.2 1.0 2.7 1.2 1.6 1.9 2.1 1.7 1.7 1.4
Medication for cholesterol 0.9 1.4 7.4 -0.1 -0.7 -2.7 -1.2 -2.0 -1.8 -1.4 -1.0 -1.0 -1.0 -1.8 0.3 0.1 -1.8 -0.1 -0.4 -0.8 -0.7 -0.6 -0.6 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.8 1.8 0.5 0.8 0.8 1.0 0.2 0.6 -1.0 1.1 1.2 0.6 1.2 -1.3 0.9 1.3 0.3 1.2 0.5 0.4 0.8 0.9 1.2
Back pain experienced in last month 0.9 1.3 9.5 1.1 0.7 1.5 1.1 3.1 1.8 -1.6 0.7 0.8 0.8 1.0 -0.3 0.7 -0.2 0.1 0.5 0.9 0.9 0.8 0.8 0.7
Mineral and other dietary supplements 1.2 1.7 3.8 -1.9 -1.5 0.5 -1.5 0.2 -0.1 0.4 -1.6 -0.9 -1.4 -1.7 2.0 -1.8 -1.1 -0.7 -1.5 -1.6 -1.2 -0.9 -1.4 -0.9
Breast cancer (self-reported) 1.7 2.0 3.6 1.1 1.7 -0.3 1.6 -0.8 -1.3 1.1 1.6 1.3 1.7 0.4 -1.1 1.5 1.6 1.3 1.4 1.7 1.9 1.7 1.7 1.4
Asthma (self-reported) 0.8 1.6 6.9 0.9 1.2 0.3 1.7 0.1 2.6 -1.6 1.6 0.7 0.9 0.7 -0.4 2.1 1.0 1.2 0.9 1.0 1.2 1.2 1.0 1.1
Osteoporosis (self-reported) 1.3 1.6 3.7 -1.5 -1.4 -1.0 -1.5 -1.3 -0.8 -0.5 -1.7 -1.1 -1.9 -0.9 1.2 -1.0 0.1 -1.7 -1.1 -1.4 -1.3 -1.1 -1.4 -1.0
Osteoarthritis (self-reported) 0.6 0.8 3.4 -0.2 -0.3 -0.2 -0.5 1.9 1.8 0.9 -0.6 -0.0 -0.3 -1.3 0.3 -1.4 -0.6 -0.7 -0.4 -0.9 -1.0 -0.9 -0.8 -0.8
Medication: Aspirin 0.6 0.8 6.2 0.6 0.2 1.1 0.9 -0.3 0.7 0.9 1.0 0.5 0.9 2.5 0.0 0.7 1.4 -0.2 0.2 0.8 0.9 0.6 0.4 0.2
Medication: Gliclazide 0.2 0.3 2.6 0.3 0.1 0.8 -0.3 1.6 -0.0 0.7 -0.2 -0.1 -0.2 0.1 -0.2 -0.7 0.9 -0.2 0.1 -0.3 -0.3 -0.2 -0.2 -0.1
Illnesses of father: None of the above (group 1) 0.7 0.9 3.3 -0.8 -0.4 1.0 -0.5 -0.3 -1.7 0.7 -0.7 -0.7 -0.2 -1.8 1.1 -1.1 -1.2 -0.5 -0.9 -0.9 -0.8 -0.8 -0.9 -0.9
Smoking status: Current 0.8 1.2 3.8 -1.1 -1.1 -0.8 -1.7 -0.7 0.2 -2.0 -1.4 -0.5 -1.5 -0.5 1.5 -0.1 -1.2 -1.1 -1.0 -1.3 -0.8 -0.6 -1.2 -0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 3.7 -1.3 0.4 0.5 0.1 1.9 -0.4 -0.3 0.4 -0.3 0.2 -1.6 -0.2 1.3 0.2 -0.3 0.3 0.1 0.1 -0.0 0.1 0.2
Whole body water mass 0.3 1.8 22.3 -0.0 0.4 0.9 0.3 2.5 1.5 1.3 -0.2 0.8 0.7 4.7 -0.2 -0.7 -0.9 0.1 -0.2 0.8 0.5 -0.1 0.2 -0.7
Leg predicted mass (right) 0.2 1.2 15.3 -0.4 -0.1 1.3 0.1 1.9 1.0 0.8 -0.4 0.4 0.1 3.9 0.4 -0.8 -0.8 -0.1 -0.5 0.3 0.2 -0.3 -0.2 -0.7
Arm fat mass (left) 0.1 0.5 1.7 -0.5 -0.7 0.9 -0.3 1.3 0.1 0.4 -0.3 -1.1 -0.8 0.4 0.3 -0.6 -1.1 -0.5 -0.7 -0.4 -0.7 -0.9 -0.6 -1.0
Number of self-reported non-cancer illnesses 0.5 0.9 3.1 -1.2 -0.7 1.8 -0.5 -1.1 1.6 0.9 -0.4 -0.7 -0.6 -0.1 1.2 0.3 0.9 -1.4 -1.2 -0.3 -0.3 -0.6 -0.9 -1.3
Average weekly champagne plus white wine intake 0.7 1.0 8.1 -0.1 -1.0 -2.8 -0.8 -0.0 -0.9 0.8 -1.0 -1.1 -0.7 0.1 0.5 -0.7 -0.8 -0.6 -1.0 -0.5 -0.8 -1.1 -1.0 -1.3
Miserableness 0.4 0.8 4.1 -0.7 -1.0 0.5 -0.8 0.4 1.3 -2.0 -1.1 -0.7 -1.1 0.0 0.9 -0.6 -0.7 -0.7 -0.7 -0.9 -0.8 -0.5 -0.7 -0.4
Guilty feelings 0.3 0.4 2.9 -0.0 0.4 1.1 0.2 1.7 1.5 -1.0 0.1 0.3 0.1 0.5 -0.7 0.3 -0.1 0.3 0.5 0.5 0.3 0.2 0.4 0.2
Wears glasses or contact lenses 0.3 0.3 2.7 0.3 -0.6 -0.1 0.1 -1.6 -0.2 -1.2 -0.0 -0.6 -0.7 0.2 -0.0 0.6 -0.5 0.0 -0.3 -0.5 -0.7 -0.3 -0.2 -0.1
Ever taken oral contraceptive pill 5.9 6.5 12.8 3.0 3.1 1.7 2.7 1.7 -0.8 1.4 2.6 2.0 3.3 2.4 -3.6 2.7 1.9 2.6 2.9 3.4 2.8 2.1 3.1 1.9
Hearing aid user 2.1 2.3 4.6 -2.0 -1.6 -1.3 -1.6 -1.2 0.4 -0.3 -1.3 -1.7 -1.5 -0.7 2.1 -1.0 -1.1 -2.1 -1.9 -1.7 -1.5 -1.5 -1.9 -1.6
Mother’s age at death 0.7 0.9 8.7 0.7 -0.5 -1.2 -0.3 -3.0 -0.9 2.4 -0.1 -0.5 0.1 0.8 0.4 0.7 0.1 -0.4 -0.2 -0.6 -0.4 -0.1 -0.3 0.0
Financial situation satisfaction 0.2 0.2 1.1 -0.1 -0.0 0.0 0.2 -0.1 -0.0 -0.2 -0.1 0.1 -0.1 0.8 -1.0 -0.9 -0.3 -0.6 -0.1 0.2 -0.5 -0.8 -0.0 -0.6
Tinnitus: Yes, now most or all of the time 0.2 0.2 1.1 0.7 -0.1 -0.7 -0.1 -0.7 -0.4 1.1 0.1 0.2 -0.4 -0.5 -0.5 0.1 0.7 -0.3 0.3 -0.5 -0.5 -0.0 0.2 0.6
Commuting to job workplace: Public transport 0.6 0.7 2.0 -0.8 -1.1 -0.3 -0.9 0.1 0.2 0.7 -0.8 -1.4 -1.0 0.3 1.4 -1.1 -1.1 -0.3 -1.2 -0.7 -0.5 -0.7 -1.0 -0.8
Eye problems/disorders: Glaucoma 0.3 0.4 1.7 1.1 0.2 -0.2 0.5 -1.0 0.7 0.9 0.4 0.5 0.6 -0.3 -0.4 0.3 1.3 0.5 0.5 0.2 0.1 0.4 0.4 0.5
Medication: Blood pressure 1.0 1.9 8.2 0.5 0.8 2.9 2.3 1.3 1.4 1.8 1.9 0.8 1.2 1.6 -0.9 -0.3 2.2 0.9 0.6 1.3 0.9 0.6 1.0 0.2
Pain type(s) experienced in last month: Hip pain 0.6 0.7 6.0 0.3 0.2 0.4 0.5 2.5 1.9 -0.8 0.2 1.1 -0.0 0.6 0.4 -0.6 -0.3 0.5 0.3 -0.3 0.2 0.7 0.2 0.8
Supplements: Fish oil (including cod liver oil) 3.1 4.1 9.3 3.0 2.1 -0.1 2.4 -0.7 -0.4 0.5 2.5 2.0 2.2 1.9 -2.3 2.3 2.0 1.8 2.5 2.1 2.0 2.1 2.3 2.2
High cholesterol (Self-reported) 2.1 3.6 9.4 -2.2 -2.0 -0.2 -1.9 -2.4 0.3 -0.0 -2.0 -1.9 -1.9 -0.8 2.1 -1.2 -0.7 -3.1 -2.3 -2.0 -2.1 -2.2 -2.5 -2.5
Medication: Bendroflumethiazide 1.6 2.5 5.5 1.0 1.6 2.3 1.6 1.9 2.3 0.6 1.8 1.4 1.5 1.9 -1.9 0.5 2.1 1.1 1.6 1.7 1.3 1.2 1.6 0.9
Medication: Paracetamol 1.8 2.7 6.3 1.8 1.9 0.8 1.2 0.2 2.1 0.1 1.7 2.2 1.4 2.0 -1.8 1.4 2.5 1.1 2.1 1.5 1.6 1.7 1.7 1.6
Medication: Lisinopril 0.7 0.8 4.5 0.8 0.6 1.0 0.8 -1.0 2.1 1.0 0.8 1.0 0.4 0.2 -0.7 0.9 1.5 0.6 0.9 0.4 0.5 0.7 0.6 0.9
Medication: Atorvastatin 0.3 0.4 2.5 -0.1 -0.4 0.9 -0.2 -0.3 1.6 -1.3 0.2 0.1 -0.7 0.6 0.1 -0.3 1.2 -0.7 -0.0 -0.3 -0.3 -0.2 -0.2 -0.0
Illnesses of father: High blood pressure 1.6 2.0 6.2 -1.7 -1.6 -2.5 -1.7 -0.5 -0.7 0.1 -1.4 -0.9 -1.5 -1.4 1.3 -0.6 -1.2 -2.0 -1.4 -1.8 -1.6 -1.3 -1.6 -1.2
Alcohol drinker status: Never 0.1 0.2 0.7 0.2 -0.2 -0.7 -0.0 0.7 0.4 -0.6 -0.3 -0.3 -0.3 -0.2 0.2 -0.9 -0.2 -0.1 -0.4 0.2 0.0 -0.4 -0.2 -0.7
Ever smoked 0.5 0.9 5.4 -0.9 -0.6 -2.3 -0.9 -0.6 -1.9 -0.0 -0.8 -0.3 -0.2 -0.1 0.9 0.5 -1.8 -0.6 -0.6 -0.5 -0.1 -0.1 -0.4 -0.2
Basal metabolic rate 0.3 1.5 19.0 -0.2 0.2 0.8 0.2 2.3 1.3 1.1 -0.3 0.6 0.5 4.4 -0.1 -0.8 -1.0 -0.0 -0.3 0.6 0.4 -0.2 0.0 -0.7
Leg fat percentage (left) 0.1 0.5 2.4 0.4 0.7 0.8 0.8 1.5 -0.7 0.4 0.9 0.0 0.5 0.2 -0.9 0.8 -0.0 0.7 0.8 0.8 0.6 0.4 0.8 0.4
Arm fat-free mass (left) 0.3 1.7 19.8 -0.1 0.4 0.9 0.2 2.6 1.3 1.5 -0.3 0.8 0.8 4.5 -0.3 -0.8 -0.9 0.0 -0.1 0.9 0.5 -0.2 0.2 -0.8
Number of operations (self-reported) 0.5 0.8 5.7 0.6 0.1 -1.0 0.2 -1.1 -2.4 2.2 0.3 0.0 0.4 -1.0 -0.2 1.0 0.7 -0.3 0.1 0.3 0.2 0.1 0.1 0.0
Average weekly beer plus cider intake 0.5 0.7 4.0 1.1 0.7 0.5 0.7 2.0 -0.2 -1.3 0.4 0.2 0.5 -0.6 -1.0 1.3 -0.3 0.1 0.9 0.5 0.4 0.6 0.8 1.0
Irritability 0.4 0.7 2.6 0.8 0.8 0.5 0.4 1.6 1.0 -1.4 0.2 1.3 0.6 1.3 -0.3 0.3 0.2 0.1 0.8 0.3 0.6 0.8 0.6 0.7
Risk taking 0.7 1.0 3.5 -0.7 -0.9 -0.8 -0.9 -1.9 -0.9 0.4 -1.1 -1.0 -1.1 -0.8 0.4 -1.1 -0.8 -1.2 -0.9 -0.6 -1.0 -1.3 -1.0 -1.1
Ever had prostate specific antigen (PSA) test 0.5 0.6 3.4 -0.3 -0.3 -0.0 0.4 -1.8 1.6 1.8 0.1 0.1 0.9 0.4 0.0 0.5 0.5 -0.5 -0.1 0.6 0.5 0.1 0.1 -0.2
Fractured/broken bones in last 5 years 0.1 0.2 1.5 0.2 -0.3 -0.2 -0.2 0.1 -1.2 0.5 0.1 -0.1 -0.4 -0.6 -0.1 -0.4 0.2 -0.5 -0.3 0.1 -0.1 -0.5 -0.2 -0.6
Age started oral contraceptive pill 0.7 0.8 6.6 1.1 0.6 -1.2 0.6 2.6 -0.7 1.2 0.8 0.1 0.5 0.1 -0.8 0.2 -0.3 1.3 0.7 0.5 0.5 0.6 0.7 0.6
Diastolic blood pressure, automated reading 0.2 0.7 3.0 -0.3 0.7 -0.3 1.3 -1.7 -0.6 -0.1 1.1 1.1 0.4 -0.5 -0.2 -0.3 1.1 1.0 0.8 0.6 0.9 0.9 0.9 0.9
Ever depressed for a whole week 0.4 0.5 1.9 -1.1 -0.5 -0.3 -0.7 -1.4 1.4 0.3 -0.4 -0.1 -0.5 -0.5 0.5 -0.8 -0.4 -1.0 -0.4 -1.0 -0.9 -0.5 -0.7 -0.2
Unable to work because of sickness or disability 1.5 1.9 5.0 0.9 1.4 1.8 1.8 0.3 1.0 0.3 1.7 0.7 1.7 1.6 -1.2 1.2 2.2 1.1 1.0 2.1 1.8 1.2 1.5 0.9
Commuting to job workplace: Cycle 0.2 0.3 2.5 0.1 0.3 -0.8 -0.4 0.2 0.3 1.0 -0.3 0.3 0.5 1.6 -0.5 0.4 -0.0 0.1 0.5 0.3 0.3 0.2 0.2 0.3
Myopia 0.5 0.7 2.7 1.0 0.8 -1.6 0.5 -0.9 1.6 -1.4 0.6 0.2 0.3 1.1 -0.5 0.7 0.5 0.8 0.5 0.5 0.6 0.5 0.5 0.3
Vascular/heart problems diagnosed by doctor 0.4 1.1 7.0 -0.4 -0.4 -1.7 -0.8 1.4 -0.8 -2.1 -0.8 -0.4 -0.9 -1.5 0.4 0.0 -2.6 0.2 0.0 -0.9 -0.6 -0.1 -0.3 0.3
Cholesterol lowering medication 0.5 0.8 7.6 -0.1 0.5 1.4 0.8 0.3 1.2 0.7 0.6 0.1 0.7 2.8 -0.0 0.3 1.6 -0.6 0.0 0.5 0.3 0.1 0.1 -0.3
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 2.9 0.5 0.9 0.5 0.7 0.9 1.7 -0.1 0.5 0.2 0.6 -0.8 -0.5 0.6 -0.4 -0.4 0.3 0.9 0.8 0.4 0.6 0.2
Pain experienced in last month 0.5 0.8 5.6 -0.2 0.0 -1.9 -0.8 -1.1 -1.9 2.4 -0.2 -0.9 0.1 -0.3 0.0 -0.3 -0.3 0.3 -0.4 -0.2 -0.2 -0.3 -0.4 -0.5
Supplements: Calcium 0.3 0.3 1.4 1.2 0.3 -0.6 0.4 -0.2 -0.8 1.2 0.4 -0.7 0.4 0.9 0.0 0.4 0.6 0.1 -0.4 0.5 0.2 -0.1 0.1 -0.6
Basal cell carcinoma (self-reported) 1.8 2.1 5.5 -0.6 -1.3 -0.2 -1.1 1.8 2.0 -1.5 -0.9 -1.3 -1.3 0.8 0.6 -2.0 -2.3 -1.6 -1.6 -0.9 -1.4 -1.8 -1.4 -1.8
Heart attack/myocardial infarction (self-reported) 2.7 3.4 7.9 -2.8 -1.9 0.2 -2.1 -1.0 -0.7 -2.7 -2.2 -1.9 -1.9 -1.0 2.3 -1.2 -0.9 -2.1 -2.0 -2.0 -1.8 -1.8 -2.2 -1.8
Deep venous thrombosis (DVT) (self-reported) 0.2 0.3 1.8 -0.3 -0.1 1.2 0.7 -0.3 -0.7 -1.3 0.3 -0.3 -0.3 -0.9 0.5 -0.7 0.3 0.2 -0.4 -0.1 -0.2 -0.1 -0.3 -0.2
Heart disease (siblings) 0.5 0.6 3.4 0.3 -0.6 -0.2 -0.1 1.4 0.2 -1.8 -0.2 -0.3 -1.0 -1.1 0.8 -1.4 -0.2 -0.3 -0.5 -0.9 -0.6 -0.3 -0.7 -0.1
Alcohol drinker status: Previous 0.3 0.4 2.4 0.8 -0.1 1.6 -0.0 0.6 -0.6 1.2 0.0 -0.9 0.4 0.9 -0.4 0.5 -0.1 -0.4 -0.3 0.3 -0.1 -0.4 0.1 -0.6
Pack years of smoking 0.5 0.8 4.5 0.6 0.8 1.4 0.6 2.1 1.7 -0.2 0.6 0.2 0.4 0.5 -0.2 1.1 0.1 0.7 0.5 0.7 0.9 0.8 0.8 0.8
Impedance of whole body 0.3 1.4 7.7 -0.5 -0.9 -2.8 -0.9 -2.5 -2.4 -1.2 -0.6 -0.8 -0.6 -1.0 1.2 -0.3 -1.0 0.1 -0.7 -0.7 -0.3 -0.1 -0.6 -0.1
Leg fat mass (left) 0.1 0.4 3.1 -0.1 0.2 1.0 0.5 1.8 -0.3 0.7 0.5 -0.1 0.1 1.3 -0.2 0.2 -0.6 0.3 0.1 0.5 0.4 -0.0 0.2 -0.3
Arm predicted mass (left) 0.3 1.7 18.3 -0.3 0.2 0.5 -0.0 2.6 1.2 1.8 -0.5 0.6 0.7 4.3 -0.2 -0.8 -1.1 -0.1 -0.3 0.7 0.3 -0.4 -0.0 -0.9