Best TWAS P=9.79e-12 · Best GWAS P=1.71e-13 conditioned to 0.00161
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MLIP | 0.14 | 0.06 | enet | 16 | 0.11 | 1.1e-13 | -6.4 | 5.4 | 7.4e-08 | -0.65 | 0.74 | 0.26 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | MLIP | 0.08 | 0.00 | bslmm | 635 | 0.03 | 3.1e-05 | -6.3 | 5.3 | 9.9e-08 | -0.61 | 0.10 | 0.82 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | C6orf142 | 0.06 | 0.01 | blup | 181 | 0.02 | 1.0e-02 | -6.4 | 6.8 | 9.8e-12 | -0.81 | 0.02 | 0.63 | TRUE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | C6orf142 | 0.27 | 0.01 | blup | 184 | 0.08 | 1.3e-03 | -7.1 | 6.4 | 1.5e-10 | -0.77 | 0.02 | 0.52 | FALSE |